This is a Validated Antibody Database (VAD) review about human Histone H1, based on 42 published articles (read how Labome selects the articles), using Histone H1 antibody in all methods. It is aimed to help Labome visitors find the most suited Histone H1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Histone H1 synonym: H1.2; H1C; H1F2; H1s-1; histone H1.2; H1 histone family, member 2; histone 1, H1c; histone H1c; histone H1d; histone H1s-1; histone cluster 1, H1c

Knockout validation
Proteintech Group
rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 3d
Proteintech Group Histone H1 antibody (Proteintech, 19649-1-AP) was used in western blot knockout validation on human samples (fig 3d). Front Immunol (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (AE-4)
  • western blot; human; loading ...; fig 4f
Santa Cruz Biotechnology Histone H1 antibody (SantaCruz, sc-8030) was used in western blot on human samples (fig 4f). Oncogene (2017) ncbi
mouse monoclonal (AE-4)
  • western blot; mouse; loading ...; fig s4
Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz Biotechnology, AE-4) was used in western blot on mouse samples (fig s4). J Cell Sci (2017) ncbi
mouse monoclonal (AE-4)
  • western blot; human; loading ...; fig 6f
Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz, sc-8030) was used in western blot on human samples (fig 6f). Sci Rep (2017) ncbi
mouse monoclonal (AE-4)
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 4a
  • immunocytochemistry; human; 1:50; fig 3
In order to examine histones as a potential nuclear proaggregant factor for alpha-synuclein aggregation in both apoptotic neurons and brains with alpha-synuclein pathology, Santa Cruz Biotechnology Histone H1 antibody (Santa, sc-8030) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 4a) and in immunocytochemistry on human samples at 1:50 (fig 3). Acta Neuropathol (2017) ncbi
mouse monoclonal (AE-4)
  • western blot; human; 1:1000; fig 3
Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz, sc-8030) was used in western blot on human samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
mouse monoclonal (AE-4)
  • western blot; mouse; loading ...; fig 9d
Santa Cruz Biotechnology Histone H1 antibody (SantaCruz, Sc-8030) was used in western blot on mouse samples (fig 9d). Am J Pathol (2016) ncbi
mouse monoclonal (AE-4)
  • western blot; mouse; 1:500; fig 3
Santa Cruz Biotechnology Histone H1 antibody (santa Cruz, sc-8030) was used in western blot on mouse samples at 1:500 (fig 3). J Am Heart Assoc (2016) ncbi
mouse monoclonal (AE-4)
  • western blot; mouse; fig 2
  • western blot; human; fig s1
Santa Cruz Biotechnology Histone H1 antibody (anta Cruz Biotechnology, SC-8030) was used in western blot on mouse samples (fig 2) and in western blot on human samples (fig s1). Nat Commun (2016) ncbi
mouse monoclonal (AE-4)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Histone H1 antibody (SCBT, AE-4) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (AE-4)
  • western blot; human; 1:250; fig 3
In order to elucidate the relationship between MITF and c-Jun in melanoma, Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz, sc-8030) was used in western blot on human samples at 1:250 (fig 3). Nat Commun (2015) ncbi
mouse monoclonal (AE-4)
  • western blot; human; 1:500; fig 1
In order to discuss the consequences of Diabetes Associated Protein in Insulin-sensitive Tissues overexpression, Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz, sc-8030) was used in western blot on human samples at 1:500 (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (AE-4)
  • western blot; human; 1:250
Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz, sc-8030) was used in western blot on human samples at 1:250. J Virol (2015) ncbi
mouse monoclonal (AE-4)
  • immunocytochemistry; mouse; fig s1
In order to assess induced Bax-regulated nuclear rupture and bubble budding followed by release of nuclear proteins due to cellular stress, Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz, sc-8030) was used in immunocytochemistry on mouse samples (fig s1). Nucleus (2014) ncbi
mouse monoclonal (AE-4)
  • western blot; human; 1:1000
Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz Biotechnology, sc-8030) was used in western blot on human samples at 1:1000. Biochim Biophys Acta (2015) ncbi
mouse monoclonal (AE-4)
  • western blot; human; 1:250
In order to test if integrin alphavbeta3 signaling promotes the release of intracellular calcium and contributes to viral entry and spread, Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz Biotechnology, sc-8030) was used in western blot on human samples at 1:250. J Virol (2014) ncbi
mouse monoclonal (AE-4)
  • western blot; human; 1:500; loading ...; fig 8c
Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz Biotechnology, sc-8030) was used in western blot on human samples at 1:500 (fig 8c). PLoS ONE (2014) ncbi
mouse monoclonal (AE-4)
  • immunohistochemistry; human
In order to study the eigenetic role of PARP-1 as a memory marker in mitotic chromatin, Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz, sc8030) was used in immunohistochemistry on human samples . Nucleic Acids Res (2014) ncbi
mouse monoclonal (AE-4)
  • western blot; mouse
Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz Biotechnology, A-E4) was used in western blot on mouse samples . Genetics (2014) ncbi
mouse monoclonal (AE-4)
  • western blot; mouse; fig 6
Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz Biotechnology, sc-8030) was used in western blot on mouse samples (fig 6). Endocrinology (2014) ncbi
mouse monoclonal (AE-4)
  • immunoprecipitation; human
  • western blot; human
Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz, sc-8030) was used in immunoprecipitation on human samples and in western blot on human samples . Cell Signal (2014) ncbi
mouse monoclonal (AE-4)
  • western blot; human; 1:500
Santa Cruz Biotechnology Histone H1 antibody (Santa Cruz, sc-8030) was used in western blot on human samples at 1:500. Int J Cancer (2011) ncbi
Abcam
rabbit monoclonal (EPR12691)
  • western blot; human; 1:2000; loading ...; fig 5b
Abcam Histone H1 antibody (Abcam, ab181977) was used in western blot on human samples at 1:2000 (fig 5b). elife (2018) ncbi
rabbit monoclonal
  • western blot; mouse; 1:2000; loading ...; fig s1a
Abcam Histone H1 antibody (Abcam, ab181973) was used in western blot on mouse samples at 1:2000 (fig s1a). Nucleic Acids Res (2018) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 6g
  • western blot; human; loading ...; fig 8a
In order to determine the molecular mechanisms that enable JAK2/signal transducer and activator of transcription 5 to access promoters of genes implicated in breast cancer pathogenesis, Abcam Histone H1 antibody (Abcam, ab4086) was used in chromatin immunoprecipitation on human samples (fig 6g) and in western blot on human samples (fig 8a). J Biol Chem (2017) ncbi
rabbit polyclonal
  • immunoprecipitation; human; fig 2
  • western blot; human; fig 1
In order to examine histones as a potential nuclear proaggregant factor for alpha-synuclein aggregation in both apoptotic neurons and brains with alpha-synuclein pathology, Abcam Histone H1 antibody (Abcam, ab17677) was used in immunoprecipitation on human samples (fig 2) and in western blot on human samples (fig 1). Acta Neuropathol (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
In order to detection by RNA-Seq of conserved senescence associated genes and pathways in primary human fibroblasts, Abcam Histone H1 antibody (Abcam, ab17677) was used in western blot on human samples at 1:1000. PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Abcam Histone H1 antibody (Abcam, ab17677) was used in western blot on human samples (fig 2). Nature (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 6
Abcam Histone H1 antibody (Abcam, ab17677) was used in western blot on human samples at 1:1000 (fig 6). Biomed Res Int (2015) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3b
Abcam Histone H1 antibody (Abcam, ab17677) was used in western blot on human samples (fig 3b). Nucleic Acids Res (2015) ncbi
rabbit polyclonal
  • western blot; human
Abcam Histone H1 antibody (Abcam, ab17677) was used in western blot on human samples . J Biol Chem (2015) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human
Abcam Histone H1 antibody (Abcam, ab4086) was used in chromatin immunoprecipitation on human samples . Nucleic Acids Res (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Abcam Histone H1 antibody (Abcam, ab17677) was used in western blot on human samples at 1:1000. Cell Death Dis (2013) ncbi
rabbit polyclonal
  • western blot; rat
Abcam Histone H1 antibody (Abcam, ab17677) was used in western blot on rat samples . Biol Reprod (2013) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human
  • western blot; human
Abcam Histone H1 antibody (Abcam, ab4086) was used in chromatin immunoprecipitation on human samples and in western blot on human samples . Oncogene (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Abcam Histone H1 antibody (Abcam, ab17677) was used in western blot on human samples (fig 4). PLoS ONE (2013) ncbi
rabbit polyclonal
  • western blot; human
Abcam Histone H1 antibody (Abcam, Ab17677) was used in western blot on human samples . EMBO J (2013) ncbi
rabbit polyclonal
  • immunocytochemistry; human
Abcam Histone H1 antibody (Abcam, ab17677) was used in immunocytochemistry on human samples . Pulm Circ (2012) ncbi
Proteintech Group
rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 3d
Proteintech Group Histone H1 antibody (Proteintech, 19649-1-AP) was used in western blot knockout validation on human samples (fig 3d). Front Immunol (2017) ncbi
Active Motif
rabbit polyclonal
  • western blot; mouse; 1:1000
Active Motif Histone H1 antibody (Active Motif, 39707) was used in western blot on mouse samples at 1:1000. PLoS ONE (2013) ncbi
EMD Millipore
rabbit polyclonal
  • immunocytochemistry; mouse; 1:300; loading ...
In order to identify Ret as a downstream mediator of DUX4 signaling, EMD Millipore Histone H1 antibody (Thermo Fisher Scientific, 06-597) was used in immunocytochemistry on mouse samples at 1:300. elife (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:300; loading ...; fig 4b
In order to investigate the contribution of DUX4 constructs to cell proliferation and differentiation, EMD Millipore Histone H1 antibody (Millipore, 06-597) was used in immunocytochemistry on mouse samples at 1:300 (fig 4b). J Cell Sci (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3b
EMD Millipore Histone H1 antibody (Upstate Biotechnology, 06-597) was used in western blot on mouse samples (fig 3b). Cell Death Dis (2016) ncbi
rabbit polyclonal
  • immunoprecipitation; mouse
  • western blot; mouse; fig 3
In order to study reduction of hyperphosphorilated Tau by beta-secretase 1's targeting implying autophagy actors in 3xTg-AD mice, EMD Millipore Histone H1 antibody (Millipore, 06-597) was used in immunoprecipitation on mouse samples and in western blot on mouse samples (fig 3). Front Cell Neurosci (2015) ncbi
Articles Reviewed
  1. Ivanyi Nagy R, Ahmed S, Peter S, Ramani P, Ong P, Dreesen O, et al. The RNA interactome of human telomerase RNA reveals a coding-independent role for a histone mRNA in telomere homeostasis. elife. 2018;7: pubmed publisher
  2. Hangas A, Aasumets K, Kekäläinen N, Paloheinä M, Pohjoismäki J, Gerhold J, et al. Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2. Nucleic Acids Res. 2018;46:9625-9636 pubmed publisher
  3. Jiang X, Bao Y, Liu H, Kou X, Zhang Z, Sun F, et al. VPS34 stimulation of p62 phosphorylation for cancer progression. Oncogene. 2017;36:6850-6862 pubmed publisher
  4. Liu X, Yang C, Hu Y, Lei E, Lin X, Zhao L, et al. HIST1H1C Regulates Interferon-? and Inhibits Influenza Virus Replication by Interacting with IRF3. Front Immunol. 2017;8:350 pubmed publisher
  5. Jha K, Tripurani S, Johnson G. TSSK6 is required for γH2AX formation and the histone-to-protamine transition during spermiogenesis. J Cell Sci. 2017;130:1835-1844 pubmed publisher
  6. Dattilo V, D Antona L, Talarico C, Capula M, Catalogna G, Iuliano R, et al. SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: a new route of epigenomic regulation. Sci Rep. 2017;7:45361 pubmed publisher
  7. Schauwecker S, Kim J, Licht J, Clevenger C. Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells. J Biol Chem. 2017;292:2237-2254 pubmed publisher
  8. Jiang P, Gan M, Yen S, McLean P, Dickson D. Histones facilitate α-synuclein aggregation during neuronal apoptosis. Acta Neuropathol. 2017;133:547-558 pubmed publisher
  9. Moyle L, Blanc E, Jaka O, Prueller J, Banerji C, Tedesco F, et al. Ret function in muscle stem cells points to tyrosine kinase inhibitor therapy for facioscapulohumeral muscular dystrophy. elife. 2016;5: pubmed publisher
  10. Knopp P, Krom Y, Banerji C, Panamarova M, Moyle L, den Hamer B, et al. DUX4 induces a transcriptome more characteristic of a less-differentiated cell state and inhibits myogenesis. J Cell Sci. 2016;129:3816-3831 pubmed
  11. Liu C, Lin S, Hsu H, Yang S, Lin C, Yang M, et al. Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Nat Commun. 2016;7:11798 pubmed publisher
  12. Shen Z, Liu Y, Dewidar B, Hu J, Park O, Feng T, et al. Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression. Am J Pathol. 2016;186:1874-1889 pubmed publisher
  13. Marthandan S, Baumgart M, Priebe S, Groth M, Schaer J, Kaether C, et al. Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq. PLoS ONE. 2016;11:e0154531 pubmed publisher
  14. Nishikido T, Oyama J, Shiraki A, Komoda H, Node K. Deletion of Apoptosis Inhibitor of Macrophage (AIM)/CD5L Attenuates the Inflammatory Response and Infarct Size in Acute Myocardial Infarction. J Am Heart Assoc. 2016;5:e002863 pubmed publisher
  15. Datan E, Roy S, Germain G, Zali N, McLean J, Golshan G, et al. Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation. Cell Death Dis. 2016;7:e2127 pubmed publisher
  16. Thornton T, Delgado P, Chen L, Salas B, Krementsov D, Fernández M, et al. Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response. Nat Commun. 2016;7:10553 pubmed publisher
  17. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  18. Piedrahita D, Castro Álvarez J, Boudreau R, Villegas Lanau A, Kosik K, Gallego Gómez J, et al. β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice. Front Cell Neurosci. 2015;9:498 pubmed publisher
  19. Riesenberg S, Groetchen A, Siddaway R, Bald T, Reinhardt J, Smorra D, et al. MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment. Nat Commun. 2015;6:8755 pubmed publisher
  20. Thorslund T, Ripplinger A, Hoffmann S, Wild T, Uckelmann M, Villumsen B, et al. Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage. Nature. 2015;527:389-93 pubmed publisher
  21. Marthandan S, Priebe S, Baumgart M, Groth M, Cellerino A, Guthke R, et al. Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts. Biomed Res Int. 2015;2015:731938 pubmed publisher
  22. Mishima Y, Jayasinghe C, Lu K, Otani J, Shirakawa M, Kawakami T, et al. Nucleosome compaction facilitates HP1γ binding to methylated H3K9. Nucleic Acids Res. 2015;43:10200-12 pubmed publisher
  23. Kontro H, Cannino G, Rustin P, Dufour E, Kainulainen H. DAPIT Over-Expression Modulates Glucose Metabolism and Cell Behaviour in HEK293T Cells. PLoS ONE. 2015;10:e0131990 pubmed publisher
  24. Mues M, Cheshenko N, Wilson D, Gunther Cummins L, Herold B. Dynasore disrupts trafficking of herpes simplex virus proteins. J Virol. 2015;89:6673-84 pubmed publisher
  25. Mayor R, Izquierdo Bouldstridge A, Millán Ariño L, Bustillos A, Sampaio C, Luque N, et al. Genome distribution of replication-independent histone H1 variants shows H1.0 associated with nucleolar domains and H1X associated with RNA polymerase II-enriched regions. J Biol Chem. 2015;290:7474-91 pubmed publisher
  26. Lindenboim L, Sasson T, Worman H, Borner C, Stein R. Cellular stress induces Bax-regulated nuclear bubble budding and rupture followed by nuclear protein release. Nucleus. 2014;5:527-41 pubmed publisher
  27. Kim T, Kim H, Kang Y, Yoon S, Lee J, Choi W, et al. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochim Biophys Acta. 2015;1850:401-10 pubmed publisher
  28. Cheshenko N, Trepanier J, González P, Eugenin E, Jacobs W, Herold B. Herpes simplex virus type 2 glycoprotein H interacts with integrin ?v?3 to facilitate viral entry and calcium signaling in human genital tract epithelial cells. J Virol. 2014;88:10026-38 pubmed publisher
  29. Clauzure M, Valdivieso A, Massip Copiz M, Schulman G, Teiber M, Santa Coloma T. Disruption of interleukin-1? autocrine signaling rescues complex I activity and improves ROS levels in immortalized epithelial cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function. PLoS ONE. 2014;9:e99257 pubmed publisher
  30. Kadota S, Nagata K. Silencing of IFN-stimulated gene transcription is regulated by histone H1 and its chaperone TAF-I. Nucleic Acids Res. 2014;42:7642-53 pubmed publisher
  31. Lodhi N, Kossenkov A, Tulin A. Bookmarking promoters in mitotic chromatin: poly(ADP-ribose)polymerase-1 as an epigenetic mark. Nucleic Acids Res. 2014;42:7028-38 pubmed publisher
  32. Mundia M, Desai V, Magwood A, Baker M. Nascent DNA synthesis during homologous recombination is synergistically promoted by the rad51 recombinase and DNA homology. Genetics. 2014;197:107-19 pubmed publisher
  33. Vellaichamy E, Das S, Subramanian U, Maeda N, Pandey K. Genetically altered mutant mouse models of guanylyl cyclase/natriuretic peptide receptor-A exhibit the cardiac expression of proinflammatory mediators in a gene-dose-dependent manner. Endocrinology. 2014;155:1045-56 pubmed publisher
  34. Severino V, Alessio N, Farina A, Sandomenico A, Cipollaro M, Peluso G, et al. Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells. Cell Death Dis. 2013;4:e911 pubmed publisher
  35. Ahmed S, Prigent S. A nuclear export signal and oxidative stress regulate ShcD subcellular localisation: a potential role for ShcD in the nucleus. Cell Signal. 2014;26:32-40 pubmed publisher
  36. Maselli J, Hales B, Robaire B. The effects of chemotherapy with bleomycin, etoposide, and cis-platinum (BEP) on rat sperm chromatin remodeling, fecundity and testicular gene expression in the progeny. Biol Reprod. 2013;89:85 pubmed publisher
  37. Shan L, Li X, Liu L, Ding X, Wang Q, Zheng Y, et al. GATA3 cooperates with PARP1 to regulate CCND1 transcription through modulating histone H1 incorporation. Oncogene. 2014;33:3205-16 pubmed publisher
  38. Tinnikov A, Samuels H. A novel cell lysis approach reveals that caspase-2 rapidly translocates from the nucleus to the cytoplasm in response to apoptotic stimuli. PLoS ONE. 2013;8:e61085 pubmed publisher
  39. Hagarman J, Motley M, Kristjansdottir K, Soloway P. Coordinate regulation of DNA methylation and H3K27me3 in mouse embryonic stem cells. PLoS ONE. 2013;8:e53880 pubmed publisher
  40. Grundy G, Rulten S, Zeng Z, Arribas Bosacoma R, Iles N, Manley K, et al. APLF promotes the assembly and activity of non-homologous end joining protein complexes. EMBO J. 2013;32:112-25 pubmed publisher
  41. Talati M, Seeley E, Ihida Stansbury K, Delisser H, McDonald H, Ye F, et al. Altered expression of nuclear and cytoplasmic histone H1 in pulmonary artery and pulmonary artery smooth muscle cells in patients with IPAH. Pulm Circ. 2012;2:340-51 pubmed publisher
  42. Wang R, Dashwood W, Nian H, LOHR C, Fischer K, Tsuchiya N, et al. NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Int J Cancer. 2011;128:2581-90 pubmed publisher