This is a Validated Antibody Database (VAD) review about human HSPA1B, based on 174 published articles (read how Labome selects the articles), using HSPA1B antibody in all methods. It is aimed to help Labome visitors find the most suited HSPA1B antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HSPA1B synonym: HSP70-1; HSP70-1B; HSP70-2; HSP70.1; HSP70.2; HSP72; HSPA1; HSX70
Knockout validation
StressMarq Biosciences mouse monoclonal (3303) |
| StressMarq Biosciences HSPA1B antibody (StressMarq, SMC-100B) was used in western blot on human samples at 1:3000 (fig 1) and in western blot knockout validation on mouse samples at 1:3000 (fig 2). ASN Neuro (2015) ncbi |
Santa Cruz Biotechnology
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa, sc-24) was used in western blot on human samples at 1:500 (fig 2h). Cell Rep (2021) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, W27) was used in western blot on human samples at 1:1000 (fig 3d, 3e) and in western blot on mouse samples at 1:1000 (fig 3d). J Biomed Sci (2021) ncbi |
mouse monoclonal (2A4) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa, Sc-59570) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 5a). Mol Neurodegener (2021) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, W27) was used in western blot on mouse samples (fig 2a). Sci Rep (2021) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in immunohistochemistry on human samples at 1:200 (fig 4). Acta Neuropathol (2021) ncbi |
mouse monoclonal (C92F3A-5) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-66048) was used in western blot on human samples (fig 2d, 4e). iScience (2021) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, sc-24) was used in western blot on human samples at 1:5000 (fig 6a). elife (2020) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, SC24) was used in western blot on mouse samples (fig 3c). BMC Cancer (2020) ncbi |
mouse monoclonal (C92F3A-5) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-66048) was used in western blot on human samples (fig 7a) and in western blot on mouse samples (fig 4d). J Clin Invest (2020) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (santa cruz, W27) was used in western blot on mouse samples (fig 1b). Biochem Biophys Res Commun (2018) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on mouse samples (fig 4i) and in western blot on human samples (fig 4h). Science (2018) ncbi |
mouse monoclonal (3A3) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, 3A3) was used in western blot on human samples (fig 5b). Virology (2018) ncbi |
mouse monoclonal (C92F3A-5) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa, sc-66048) was used in western blot on human samples at 1:1000 (fig ex1m). Nature (2018) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa, W27) was used in western blot on human samples at 1:1000 (fig 7i). Mol Cell Biol (2018) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (SantaCruz, sc-24) was used in western blot on human samples (fig s4g). Cell (2018) ncbi |
mouse monoclonal (W27) |
| In order to investigate the involvement of HspBP1 in the neuronal susceptibility towards misfolded proteins, Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on human samples (fig s2b), in immunohistochemistry on mouse samples (fig s3c) and in western blot on mouse samples (fig s3a). Proc Natl Acad Sci U S A (2017) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, SC24) was used in western blot on human samples at 1:500 (fig 1). Sci Rep (2017) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on human samples (fig s3a). Oncoimmunology (2016) ncbi |
mouse monoclonal (W27) |
| In order to demonstrate that some mitochondrial enzymes associated with the tricarboxylic acid cycle are essential for epigenetic remodeling and transiently localize to the nucleus, Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc24) was used in immunohistochemistry on mouse samples at 1:50 (fig s6g). Cell (2017) ncbi |
mouse monoclonal (W27) |
| In order to report that cathepsin S inhibition sensitizes cancer cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis, Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on human samples (fig 6d). Antioxid Redox Signal (2017) ncbi |
mouse monoclonal (4E7) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-69705) was used in western blot on human samples (fig 5a). Sci Rep (2016) ncbi |
mouse monoclonal (F-3) |
| Santa Cruz Biotechnology HSPA1B antibody (SantaCruz, sc-373867) was used in immunocytochemistry on mouse samples (fig 4h). EBioMedicine (2016) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on human samples (fig 2a). Oncotarget (2016) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, W27) was used in immunohistochemistry on mouse samples (fig s3). Sci Rep (2016) ncbi |
mouse monoclonal (W27) |
| In order to determine the effect of a mixture of two monoclonal antibodies against non-overlapping epitopes of HER2 on HER2 stability and localization, Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, W27) was used in western blot on human samples (fig 5a). J Cell Mol Med (2016) ncbi |
mouse monoclonal (C92F3A-5) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, SC-66048) was used in western blot on mouse samples at 1:200 (fig 3). Front Microbiol (2016) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on human samples (fig 3). Sci Rep (2016) ncbi |
mouse monoclonal (4G4) |
| In order to characterize novel pancreas-targeting activity through the binding of Sec 61 by Apratoxin A, Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, 4G4) was used in immunoprecipitation on human samples (fig 3). Mol Cancer Ther (2016) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on rat samples (fig 5e). Cell Signal (2016) ncbi |
mouse monoclonal (4G4) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-59569) was used in western blot on human samples . J Mol Med (Berl) (2016) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on mouse samples at 1:1000 (fig 8). Oncotarget (2016) ncbi |
mouse monoclonal (C92F3A-5) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnologies, C92F3A-5) was used in western blot on mouse samples at 1:1000 (fig 8). Sci Rep (2016) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (santa Cruz, SC-24) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 2). Cancer Sci (2016) ncbi |
mouse monoclonal (W27) |
| In order to study hepatocellular carcinoma and ectopic lymphoid structures function as microniches for tumor progenitor cells, Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, sc-24) was used in immunohistochemistry - paraffin section on human samples (fig 4). Nat Immunol (2015) ncbi |
mouse monoclonal (W27) |
| In order to discuss factors that contribute to the onset and progression of oculopharyngeal muscular dystrophy, Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on mouse samples . PLoS ONE (2015) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on human samples (fig 2). Int J Mol Sci (2015) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa cruz, sc-24) was used in western blot on human samples (fig 4,5,6). Nucleic Acids Res (2015) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on human samples at 1:1000 (fig 1). J Extracell Vesicles (2015) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, sc-24) was used in western blot on human samples at 1:2000 (fig 5b). Nat Commun (2015) ncbi |
mouse monoclonal (W27) |
| In order to describe a method for the quantification and characterization of exosomes and microvesicles, Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on human samples . J Extracell Vesicles (2015) ncbi |
mouse monoclonal (W27) |
| In order to study the role of melanoma cell surface-associated calreticulin in melphalan-induced antitumor immunity, Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, SC-24) was used in flow cytometry on human samples . Cancer Res (2015) ncbi |
mouse monoclonal (2A4) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-59570) was used in western blot on mouse samples (fig s3). PLoS ONE (2015) ncbi |
mouse monoclonal (B-12) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, sc-137239) was used in western blot on human samples (fig 2). Mol Cancer Ther (2015) ncbi |
mouse monoclonal (BRM-22) |
| In order to investigate how transport Hedgehog via exosomes along cytonemes helps establish a gradient of expression, Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, BRM-22) was used in immunoprecipitation on fruit fly |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, sc-24) was used in western blot on human samples . FEBS Lett (2014) ncbi |
mouse monoclonal (3A3) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, sc32239) was used in western blot on mouse samples . Growth Factors (2015) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, SC-24) was used in western blot on redtail notho samples at 1:1000. Rejuvenation Res (2014) ncbi |
mouse monoclonal (BRM-22) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, SC-59572) was used in western blot on bovine samples at 1:250. J Agric Food Chem (2014) ncbi |
mouse monoclonal (3A3) |
| In order to study prostate cancer growth and the homeostatic regulation between tumor suppressor DAB2IP and ocogenic Skp2, Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, 32239) was used in western blot on human samples (fig 1). Oncotarget (2014) ncbi |
mouse monoclonal (SPM254) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-65521) was used in western blot on human samples . Oncogene (2014) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, sc-24) was used in western blot on rat samples at 1:500. Exp Neurol (2014) ncbi |
mouse monoclonal (B-12) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, B12) was used in western blot on human samples (fig 5). PLoS ONE (2014) ncbi |
mouse monoclonal (C92F3A-5) |
| In order to demonstrate that p38MAPK activation elevates mitochondrial ROS levels, Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, sc-66048) was used in western blot on mouse samples (fig 1, 2). Cell Commun Signal (2014) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-24) was used in western blot on human samples (fig 2b). Int J Oncol (2014) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, sc-24) was used in western blot on bee |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz Biotechnology, sc-24) was used in western blot on human samples at 1:1000. Neuromolecular Med (2014) ncbi |
mouse monoclonal (W27) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa cruz, sc-24) was used in western blot on human samples (fig 8b). Oncogene (2014) ncbi |
mouse monoclonal (3A3) |
| Santa Cruz Biotechnology HSPA1B antibody (Santa Cruz, sc-32239) was used in western blot on human samples at 1:1000. Mol Pharmacol (2013) ncbi |
Invitrogen
mouse monoclonal (JG1) |
| Invitrogen HSPA1B antibody (Thermo Fisher Scientific, MA3-028) was used in western blot on mouse samples (fig 1e). Cell Res (2020) ncbi |
mouse monoclonal (JG1) |
| Invitrogen HSPA1B antibody (Thermo Fisher Scientific, MA3-028) was used in western blot on mouse samples (fig 7a). J Biol Chem (2018) ncbi |
mouse monoclonal (JG1) |
| In order to elucidate the regulatory mechanisms of FAM5C biosynthesis, Invitrogen HSPA1B antibody (Thermo Fisher Scientific, MA3-028) was used in immunocytochemistry on human samples (fig 2c). Biochem Biophys Res Commun (2017) ncbi |
mouse monoclonal (JG1) |
| In order to determine that HSPA9 knockdown is associated with increased TP53 expression and activity, Invitrogen HSPA1B antibody (Affinity BioReagents, MA3-028) was used in western blot on human samples (fig 1a). PLoS ONE (2017) ncbi |
mouse monoclonal (JG1) |
| In order to identify components of mitochondrial RNA granules, Invitrogen HSPA1B antibody (Thermo Fisher Scientific, MA3-028) was used in western blot on human samples (fig 3c). J Biol Chem (2017) ncbi |
mouse monoclonal (3A3) |
| In order to elucidate the antiproliferative and pro-apoptotic effects of thiazine[6,5-b]indole, Invitrogen HSPA1B antibody (Affinity BioReagents, MA3-006) was used in western blot on human samples at 1:200 (fig 5). Biomed Pharmacother (2017) ncbi |
mouse monoclonal (3A3) | In order to measure biochemical and organismal responses to acute heat stress on two neritic copepods, Invitrogen HSPA1B antibody (Thermo Scientific, MA3-006) was used . Comp Biochem Physiol A Mol Integr Physiol (2017) ncbi | |
mouse monoclonal (2A4) |
| In order to demonstrate the bipartite role of Hsp90 in chaperoning CRAF kinase, Invitrogen HSPA1B antibody (Thermo Pierce, MA3-008) was used in western blot on human samples at 1:5000 (fig 1a). J Biol Chem (2016) ncbi |
mouse monoclonal (JG1) |
| In order to test if mitochondrial calcium uniporter concentrated at the mitochondria-sarcoplasmic reticulum interface promotes calcium transfer, Invitrogen HSPA1B antibody (Thermo Scientific, MA3-028) was used in immunohistochemistry on rat samples at 1:50 and in western blot on rat samples at 1:500 (fig 8b). J Biol Chem (2016) ncbi |
mouse monoclonal (JG1) |
| In order to report that E4F1 is a master regulator of the pyruvate dehydrogenase complex, Invitrogen HSPA1B antibody (Thermo Fisher, MA3- 028) was used in western blot on mouse samples (fig 4h). Proc Natl Acad Sci U S A (2016) ncbi |
mouse monoclonal (3A3) |
| In order to test if exposure to non-lethal heat shock increases the tolerance of Artemia franciscana to subsequent metal exposure, Invitrogen HSPA1B antibody (Affinity BioReagents, 3A3) was used in western blot on Artemia franciscana samples at 1:5000 (fig 2a) and in western blot on human samples at 1:5000. Environ Res (2016) ncbi |
mouse monoclonal (JG1) |
| In order to demonstrate that DGAT2 and MGAT2 are substrates of the endoplasmic reticulum-associated degradation pathway, Invitrogen HSPA1B antibody (Thermo Pierce, MA3-028) was used in western blot on human samples (fig 1c). Biochem J (2016) ncbi |
domestic rabbit polyclonal |
| In order to test if Hsp70 and the 20S proteasome cooperate to selectively degrade oxidatively damaged proteins, Invitrogen HSPA1B antibody (Thermo Fisher Scientific, PA5-28003) was used in western blot on mouse samples (fig 6a). Free Radic Biol Med (2016) ncbi |
mouse monoclonal (3A3) |
| In order to investigate the function of extended synaptotagmins in knock out mice, Invitrogen HSPA1B antibody (Thermo Scientific, MA3-0066) was used in western blot on mouse samples at 1:1000 (fig 3c). PLoS ONE (2016) ncbi |
mouse monoclonal (MB-H1) |
| In order to investigate evidence for two distinct pathogenetic pathways by studing the squamous cell carcinoma of the oral cavity and cytokeratin and protein expression patterns, Invitrogen HSPA1B antibody (Invitrogen, 33-3800) was used in immunohistochemistry - paraffin section on human samples at 1:40 (tbl 3). Oncol Lett (2016) ncbi |
mouse monoclonal (3A3) | In order to assess the effect of salinity on catfish's susceptibility to bacterial infection, Invitrogen HSPA1B antibody (ThermoScientific, 3A3) was used . Fish Shellfish Immunol (2016) ncbi | |
mouse monoclonal (3A3) |
| In order to study salinity and thermal stress in wild and farmed Pacific oysters Crassostrea gigas, Invitrogen HSPA1B antibody (Affinity BioReagents, MA3-006) was used in western blot on Pacific oyster samples at 1:2500 (fig 1). Comp Biochem Physiol A Mol Integr Physiol (2016) ncbi |
mouse monoclonal (JG1) |
| In order to study placental mammal-specific mitochondrial pyruvate carrier subunit called MPC1-like and its expression in post-meiotic male germ cells, Invitrogen HSPA1B antibody (Thermo Scientific, MA3-028) was used in western blot on human samples (fig 2). J Biol Chem (2016) ncbi |
mouse monoclonal (JG1) |
| In order to investigate the contribution of PINK1 and PARKIN to cell death, Invitrogen HSPA1B antibody (Thermo Scientific, JG1) was used in western blot on human samples (fig 2f). J Biol Chem (2016) ncbi |
mouse monoclonal (5A5) |
| In order to determine the affect of cellular bioenergetics in marine molluscs and functional reorganization of mitochondria by intermittent hypoxia, Invitrogen HSPA1B antibody (Affinity Bioreagents, MA3-007) was used in western blot on scallops samples (fig 7). J Exp Biol (2016) ncbi |
mouse monoclonal (JG1) |
| In order to study the reprogramming of glucose metabolism in cancer cells by ROS-mediated stabilization of HIF1alpha via the immunoregulatory protein B7-H3, Invitrogen HSPA1B antibody (Thermo Fisher Scientific, MA3-028) was used in western blot on human samples (fig 5). Cancer Res (2016) ncbi |
mouse monoclonal (JG1) |
| In order to assess the impact of brain endocannabinoid system in male mice by Fabp-1 gene ablation, Invitrogen HSPA1B antibody (Pierce Antibodies, MA3-028) was used in western blot on mouse samples (fig 6). J Neurochem (2016) ncbi |
mouse monoclonal (5A5) |
| In order to calculate how ionizing radiation can promote cell survival in exosomes derived from squamous head and neck cancer, Invitrogen HSPA1B antibody (Affinity Bioreagents, MA3-007) was used in western blot on human samples (fig 1). PLoS ONE (2016) ncbi |
mouse monoclonal (JG1) |
| In order to study increased dissociation of hexokinase II from mitochondrial outer membrane by overexpression or ErbB2 rendering breast cancer cells susceptible to 3-BrPA, Invitrogen HSPA1B antibody (Thermo Scientific, MA3-028) was used in western blot on human samples at 1:1000 (fig 4). Oncol Lett (2016) ncbi |
mouse monoclonal (JG1) |
| In order to study human 'brite/beige' adipocytes and how they develop from capillary networks and how their implantation improves metabolic homeostasis in mice, Invitrogen HSPA1B antibody (ThermoFisher, MA3-028) was used in immunocytochemistry on human samples (fig 2). Nat Med (2016) ncbi |
mouse monoclonal (JG1) |
| In order to elucidate how inhibition of vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation occurs by glucagon-like peptide 1, Invitrogen HSPA1B antibody (ABR, MA3-028) was used in western blot on rat samples at 1:1000 (fig 1). Biochem Pharmacol (2016) ncbi |
mouse monoclonal (JG1) |
| In order to report a role for adenomatous polyposis coli in the transport of mitochondria, Invitrogen HSPA1B antibody (ThermoScientific, MA3-028) was used in immunocytochemistry on human samples at 1:500 (fig s1) and in western blot on human samples at 1:500 (fig 1). Mol Biol Cell (2016) ncbi |
mouse monoclonal (JG1) |
| In order to perform a mutagenesis screen for modifiers of epigenetic gene silencing using a cell line with a mutation in Trim33, Invitrogen HSPA1B antibody (Scoresby VIC, MA3-028) was used in western blot on mouse samples (fig 4). PLoS Genet (2015) ncbi |
mouse monoclonal (3A3) |
| In order to determine the affects of dendritic cell migration in vitro by loss of gadkin, Invitrogen HSPA1B antibody (Affinity Bioreagents, MA3006) was used in western blot on mouse samples at 1:5000 (fig 1). PLoS ONE (2015) ncbi |
mouse monoclonal (JG1) |
| In order to assess how chronic cerebral hypoperfusion and repeated low-dose progesterone treatment affect neurodegenerative processes and behavior, Invitrogen HSPA1B antibody (Thermo Fisher Scientific, MA3-028) was used in western blot on rat samples . Neuroscience (2015) ncbi |
mouse monoclonal (3A3) |
| In order to examine the effect of sun exposure on of thermal refugia, Invitrogen HSPA1B antibody (Thermo Scientific, MA3-006) was used in western blot on common limpet samples at 1:1000. Glob Chang Biol (2016) ncbi |
mouse monoclonal (JG1) |
| In order to identify residues of VDAC2 that are important for Bak recruitment and function, Invitrogen HSPA1B antibody (Thermo Scientific, MA3-028) was used in western blot on mouse samples (fig 1d). Proc Natl Acad Sci U S A (2015) ncbi |
mouse monoclonal (JG1) |
| In order to test if nanocurcumin protects primary human ventricular cardiomyocytes from hypoxia-induced damages, Invitrogen HSPA1B antibody (ThermoFischer Scientific, MA3-028) was used in immunocytochemistry on human samples at 1:100 (fig 7). PLoS ONE (2015) ncbi |
mouse monoclonal (JG1) |
| In order to investigate the role of mitochondrial ATR during the response to UV damage, Invitrogen HSPA1B antibody (Thermo Scientific., MA3-028) was used in western blot on human samples (fig 2a). Mol Cell (2015) ncbi |
mouse monoclonal (3A3) |
| In order to test if non-lethal heat shock of Perna viridis promotes the production of Hsp70 and enhances its resistance to stresses, Invitrogen HSPA1B antibody (Thermo Scientific, MA3-006) was used in western blot on Asian green mussel samples at 1:5000 (fig 2). PLoS ONE (2015) ncbi |
mouse monoclonal (JG1) |
| In order to investigate centrosome regulation during fever, Invitrogen HSPA1B antibody (Affinity Bioreagents, MA3-028) was used in immunocytochemistry on human samples . Mol Biol Cell (2015) ncbi |
domestic rabbit polyclonal | In order to identify proteins in syncytiotrophoblast extracellular vesicles and determine their role in preeclampsia, Invitrogen HSPA1B antibody (Thermo Fisher, PA5-28003) was used . Cell Physiol Biochem (2015) ncbi | |
mouse monoclonal (W27) |
| In order to investigate ANP32C-Hsp90 interactions, Invitrogen HSPA1B antibody (Thermo Scientific, MA1-90504) was used in western blot on human samples (fig 2). Biochim Biophys Acta (2015) ncbi |
mouse monoclonal (JG1) |
| In order to describe the localization of BARD1 and study its interaction with p53, Invitrogen HSPA1B antibody (Affinity Bioreagents, MA3-028) was used in western blot on human samples at 1:300. Cell Signal (2015) ncbi |
mouse monoclonal (3A3) |
| In order to study HSP70 in Apostichopus japonicus, Invitrogen HSPA1B antibody (Thermo, MA3-006) was used in immunohistochemistry on holothurians samples at 1:200 and in western blot on holothurians samples at 1:1000. Fish Shellfish Immunol (2015) ncbi |
mouse monoclonal (JG1) |
| In order to determine the strain- and sex-dependent glomerular extracellular matrix signatures, Invitrogen HSPA1B antibody (Thermo Fisher Scientific, MA3-028) was used in western blot on mouse samples (fig 1). J Am Soc Nephrol (2015) ncbi |
mouse monoclonal (JG1) |
| In order to assess the effect of matrine on STAT3 signaling in cholangiocarcinoma cells, Invitrogen HSPA1B antibody (Thermo, MA3-028) was used in western blot on human samples . Pharmacol Rep (2015) ncbi |
mouse monoclonal (JG1) |
| In order to study phosphorylation events at sites of adhesion, Invitrogen HSPA1B antibody (Thermo Fisher Scientific, MA3028) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2015) ncbi |
mouse monoclonal (W27) |
| In order to use a cell culture model for aromatase inhibitor-resistant breast cancer to show how fulvestrant treatment and cross-resistance between exemestane and letrozole shows sensitivity, Invitrogen HSPA1B antibody (Neomarkers, MS-482-PO) was used in western blot on human samples (fig 3). Int J Oncol (2015) ncbi |
mouse monoclonal (5A5) |
| In order to elucidate the factors that mediate radiation-induced endothelial dysfunction, Invitrogen HSPA1B antibody (scbt, MA3-007) was used in western blot on mouse samples . J Proteome Res (2015) ncbi |
mouse monoclonal (JG1) |
| In order to assess the effects of Hspa9 haploinsufficiency on hematopoiesis using zebrafish, Invitrogen HSPA1B antibody (Pierce, MA3-028) was used in western blot on mouse samples (fig 1d). Exp Hematol (2015) ncbi |
mouse monoclonal (3A3) |
| In order to study the temporal regulation of MyoD in skeletal muscle differentiation, Invitrogen HSPA1B antibody (ABR Affinity Bio Reagents, MA3-006) was used in western blot on mouse samples (fig 2). Dev Dyn (2015) ncbi |
mouse monoclonal (JG1) |
| In order to determine the effect of zerumbone on p53 signaling and assess if zerumbone has anti-cancer effects on non-small cell lung cancer, Invitrogen HSPA1B antibody (Thermo Scientific, MA3-028) was used in western blot on human samples . Biochimie (2014) ncbi |
mouse monoclonal (JG1) |
| In order to elucidate type I interferon-independent viral immune responses, Invitrogen HSPA1B antibody (Thermo, MA3-028) was used in immunocytochemistry on human samples (fig 5). Nat Immunol (2014) ncbi |
mouse monoclonal (JG1) |
| In order to study the function of mitochondrial ErbB2, Invitrogen HSPA1B antibody (Thermo Scientific, MA3-028) was used in western blot on human samples (fig 2). Nat Commun (2012) ncbi |
mouse monoclonal (5A5) |
| In order to test the thermal co-adaptation hypothesis using Drosophila subobscura, Invitrogen HSPA1B antibody (Thermo Scientific, 5A5) was used in ELISA on fruit fly |
mouse monoclonal (5A5) |
| In order to evaluate if the use of constant temperatures is justified when studying Lycaena tityrus, Invitrogen HSPA1B antibody (Affinity BioReagents, 5A5) was used in ELISA on Lycaena tityrus samples at 1:700 (fig 2c). Oecologia (2011) ncbi |
mouse monoclonal (JG1) |
| In order to investigate the mitochondrial targeting of p14ARF tumor suppressor, Invitrogen HSPA1B antibody (Affinity Bioreagents, JG1) was used in western blot on human samples (fig 1c). Cell Cycle (2010) ncbi |
mouse monoclonal (JG1) |
| In order to report a method to isolate complexes associated with integrin adhesion receptors, Invitrogen HSPA1B antibody (Affinity BioReagents, JG1) was used in western blot on human samples . Sci Signal (2009) ncbi |
mouse monoclonal (JG1) |
| In order to identify p38MAPK as an activator of Bax, Invitrogen HSPA1B antibody (Affinity Bioreagents, MA3-028) was used in immunocytochemistry on mouse samples and in western blot on mouse samples (fig 2d). Cell Death Differ (2009) ncbi |
mouse monoclonal (3A3) |
| In order to study the effect of acclimation salinity on the stress protein response in two sibling species of Marenzelleria, Invitrogen HSPA1B antibody (Affinity BioReagents, MA3-006) was used in western blot on human samples at 1:3000 and in western blot on Marenzelleria viridis samples at 1:3000 (fig 7a). Comp Biochem Physiol B Biochem Mol Biol (2006) ncbi |
mouse monoclonal (3A3) |
| In order to find factors that interact with N-myristoylated Arf6, Invitrogen HSPA1B antibody (Affinity Bioreagents, 3A3) was used in western blot on rat samples (fig 2a). Methods Enzymol (2005) ncbi |
mouse monoclonal (JG1) |
| In order to study Bid interactions with Bax during apoptosis, Invitrogen HSPA1B antibody (Affinity Bioreagents, MA3-028) was used in western blot on human samples (fig 4). J Cell Biol (1999) ncbi |
Abcam
mouse monoclonal (3A3) |
| Abcam HSPA1B antibody (Abcam, ab5439) was used in immunocytochemistry on human samples at 1:1000 (fig 4a) and in western blot on human samples at 1:2000 (fig 2b). Cell Mol Life Sci (2022) ncbi |
mouse monoclonal (5A5) |
| Abcam HSPA1B antibody (Abcam, ab2787) was used in western blot on human samples (fig 6e). Cell Death Dis (2021) ncbi |
mouse monoclonal (5A5) |
| Abcam HSPA1B antibody (Abcam, ab2787) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 4a) and in western blot on mouse samples at 1:1000 (fig 2a). Mol Med (2021) ncbi |
mouse monoclonal (5A5) |
| Abcam HSPA1B antibody (Abcam, 2787) was used in immunohistochemistry on mouse samples at 1:200 (fig 7d). J Clin Invest (2021) ncbi |
mouse monoclonal (5A5) |
| Abcam HSPA1B antibody (Abcam, ab2787) was used in western blot on mouse samples at 1:1000 (fig 2c). Acta Neuropathol Commun (2020) ncbi |
mouse monoclonal (5A5) |
| Abcam HSPA1B antibody (Abcam, ab2787) was used in western blot on rat samples at 1:800 (fig 4a). Aging (Albany NY) (2020) ncbi |
domestic rabbit monoclonal (EPR16892) |
| Abcam HSPA1B antibody (Abcam, ab204690) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1f). Nat Cell Biol (2020) ncbi |
domestic rabbit polyclonal |
| Abcam HSPA1B antibody (Abcam, ab79852) was used in western blot on mouse samples at 1:1000 (fig s6c). Sci Adv (2019) ncbi |
mouse monoclonal (3A3) |
| Abcam HSPA1B antibody (Abcam, ab5439) was used in western blot on human samples (fig s2j). Cell (2019) ncbi |
mouse monoclonal (5A5) |
| Abcam HSPA1B antibody (Abcam, ab2787) was used in western blot on human samples (fig s2). BMC Cancer (2019) ncbi |
domestic rabbit monoclonal |
| Abcam HSPA1B antibody (Abcam, ab45133) was used in western blot on human samples (fig 1). Emerg Microbes Infect (2019) ncbi |
mouse monoclonal (3A3) |
| Abcam HSPA1B antibody (Abcam, ab5439) was used in western blot on brewer's yeast samples at 1:1000 (fig 4c). elife (2019) ncbi |
mouse monoclonal (5A5) |
| Abcam HSPA1B antibody (Abcam, ab2787) was used in western blot on human samples at 1:1000 (fig 6d). EMBO Mol Med (2019) ncbi |
mouse monoclonal (3A3) |
| Abcam HSPA1B antibody (Abcam, ab5439) was used in immunocytochemistry on human samples (fig 6b). EMBO J (2018) ncbi |
mouse monoclonal (5A5) |
| Abcam HSPA1B antibody (Abcam, ab2787) was used in western blot on mouse samples (fig 5e). J Lipid Res (2017) ncbi |
domestic rabbit polyclonal |
| Abcam HSPA1B antibody (Abcam, ab79852) was used in western blot on human samples (fig 4b). Mol Syst Biol (2017) ncbi |
domestic rabbit monoclonal (EPR16892) |
| Abcam HSPA1B antibody (abcam, ab181606) was used in western blot on mouse samples (fig 2), in immunocytochemistry on human samples (fig s3) and in western blot on human samples (fig 1). Cell (2016) ncbi |
domestic rabbit monoclonal (EPR16892) |
| In order to test if the combination of dendritic cells and doxorubicin results in tumor growth inhibition in a murine osteosarcoma model, Abcam HSPA1B antibody (Abcam, ab181606) was used in immunocytochemistry on mouse samples at 1:500 (fig 2a) and in immunohistochemistry on mouse samples at 1:200 (fig 4b). Oncol Lett (2016) ncbi |
mouse monoclonal (3A3) |
| In order to characterize dermatomyositis with or without anti-melanoma differentiation-associated gene 5 antibodies that show distinct NOS2 expression but a common interferon signature, Abcam HSPA1B antibody (Abcam, 3A3) was used in immunohistochemistry - frozen section on human samples (fig 5). Am J Pathol (2016) ncbi |
mouse monoclonal (3A3) |
| Abcam HSPA1B antibody (Abcam, ab5439) was used in immunohistochemistry on guinea pig samples (fig 2). Cell Death Dis (2016) ncbi |
mouse monoclonal (3A3) |
| Abcam HSPA1B antibody (Abcam, ab5439) was used in western blot on human samples (fig 2). Sci Rep (2016) ncbi |
mouse monoclonal (5A5) |
| Abcam HSPA1B antibody (Abcam, ab2787) was used in western blot on pigs |
mouse monoclonal (3A3) |
| Abcam HSPA1B antibody (Abcam, ab5439) was used in immunohistochemistry - frozen section on rat samples at 1:50 and in western blot on rat samples at 1:1000. Theranostics (2013) ncbi |
mouse monoclonal (5A5) |
| Abcam HSPA1B antibody (Abcam, ab2787) was used in western blot on mouse samples . Proteomics (2014) ncbi |
StressMarq Biosciences
mouse monoclonal (3303) |
| StressMarq Biosciences HSPA1B antibody (StressMarq, C92F3A-5) was used in western blot on human samples at 1:1000 (fig 6h, 2g, 6s1e). elife (2019) ncbi |
domestic rabbit polyclonal |
| StressMarq Biosciences HSPA1B antibody (StressMarq Biosciences, SPC-103D) was used in western blot on human samples (fig 6a). Autophagy (2017) ncbi |
mouse monoclonal (3303) |
| StressMarq Biosciences HSPA1B antibody (StressMarq, SMC-100B) was used in western blot on human samples at 1:3000 (fig 1) and in western blot knockout validation on mouse samples at 1:3000 (fig 2). ASN Neuro (2015) ncbi |
mouse monoclonal (3303) |
| StressMarq Biosciences HSPA1B antibody (StressMarq Biosciences Inc, SMC-100B) was used in western blot on rat samples . PLoS ONE (2014) ncbi |
mouse monoclonal (3303) |
| StressMarq Biosciences HSPA1B antibody (StressMarq, SMC-100) was used in western blot on human samples at 1:1000 (fig 6). Cell Death Dis (2013) ncbi |
Agrisera
domestic rabbit polyclonal | Agrisera HSPA1B antibody (Agrisera, AS05 083A) was used . J Exp Biol (2016) ncbi |
Abnova
mouse monoclonal (3B7) |
| In order to examine the relationships among a list of 23 protein biomarkers with CIE-L*a*b* meat color traits and ultimate pH on muscles of Maine-Anjou cows, Abnova HSPA1B antibody (Abnova, 3B7) was used in western blot on bovine samples at 1:3000 (tbl 1). J Agric Food Chem (2017) ncbi |
Novus Biologicals
domestic rabbit polyclonal |
| In order to study how focused, low-intensity ultrasound can reverse tumor-induced T cell tolerance and prevent immune escape, Novus Biologicals HSPA1B antibody (Novus Biologicals, NBP1-77455) was used in immunohistochemistry - frozen section on mouse samples (fig 4). J Immunol (2016) ncbi |
Rockland Immunochemicals
mouse monoclonal (C92F3A-5) |
| Rockland Immunochemicals HSPA1B antibody (Rockland, 200-301-A27) was used in western blot on human samples (fig 4). ASN Neuro (2015) ncbi |
Cell Signaling Technology
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling Technology, 4872T) was used in western blot on mouse samples at 1:1000 (fig 4a). Cells (2021) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4872) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 3b). Cancers (Basel) (2021) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (CST, 4872) was used in western blot on human samples at 1:500 (fig s3b). Nat Commun (2020) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4872) was used in western blot on mouse samples (fig s1c). Sci Adv (2019) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4872) was used in western blot on human samples (fig 6g). Cancer Cell (2018) ncbi |
rat monoclonal (6B3) |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 6B3) was used in immunocytochemistry on human samples at 1:50 (fig 6e) and in western blot on human samples at 1:1000 (fig 6a). Sci Rep (2018) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4876) was used in western blot on mouse samples (fig 3b). Life Sci (2018) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4872) was used in western blot on human samples (fig s5e). Cell (2018) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4872) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4872) was used in western blot on rat samples (fig 4b). J Biol Chem (2018) ncbi |
domestic rabbit polyclonal |
| In order to investigate the involvement of HspBP1 in the neuronal susceptibility towards misfolded proteins, Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4872S) was used in western blot on human samples (fig s2b), in immunohistochemistry on mouse samples (fig s3c) and in western blot on mouse samples (fig s3a). Proc Natl Acad Sci U S A (2017) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (cell signalling, 4876) was used in western blot on human samples (fig 2a). Oxid Med Cell Longev (2017) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4872) was used in western blot on human samples (fig 3b, 3c). Mol Cell (2017) ncbi |
domestic rabbit polyclonal |
| In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology HSPA1B antibody (CST, 4872) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi |
rat monoclonal (6B3) |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4873) was used in western blot on human samples (fig 2a). Oncotarget (2017) ncbi |
rat monoclonal (6B3) |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4873) was used in western blot on mouse samples (fig s2b). J Exp Med (2017) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (Cell Signalling, 4872) was used in western blot on human samples (fig 2a). Oncotarget (2016) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4872S) was used in immunohistochemistry - paraffin section on rat samples (fig 4a) and in western blot on rat samples at 1:1000 (fig 1a). Mol Med Rep (2016) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4876) was used in western blot on human samples (fig 3c). Oncotarget (2016) ncbi |
domestic rabbit polyclonal |
| In order to assess the effect of shepherdin, a peptido-mimetic that inhibits the heat shock protein-Survivin interaction, in retinoblastoma, Cell Signaling Technology HSPA1B antibody (Cell signaling, 4872) was used in flow cytometry on human samples at 1:25 (fig 1b), in immunohistochemistry on human samples (fig 1a) and in western blot on human samples at 1:500 (fig 1d). Chem Biol Interact (2016) ncbi |
rat monoclonal (6B3) |
| In order to determine limits on FAK-dependent invasion and enhancement of the response to melanoma treatment with BRAF inhibitors due to HSP70 inhibition, Cell Signaling Technology HSPA1B antibody (Cell signaling, 4873S) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 6) and in western blot on human samples (fig 2). Cancer Res (2016) ncbi |
rat monoclonal (6B3) |
| Cell Signaling Technology HSPA1B antibody (Cell signaling, 4873) was used in western blot on human samples (fig 3). Cancer Biol Ther (2015) ncbi |
rat monoclonal (6B3) |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4873) was used in western blot on human samples (fig 7). Autophagy (2015) ncbi |
rat monoclonal (6B3) |
| In order to examine the role of Trx family proteins in neuronal development and recovery after hypoxia/ischemia and reperfusion, Cell Signaling Technology HSPA1B antibody (cst, 4873s) was used in western blot on rat samples . Biochim Biophys Acta (2015) ncbi |
rat monoclonal (6B3) | In order to assess EGF receptor and its signaling using different ligands, Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4873) was used . Growth Factors (2014) ncbi | |
rat monoclonal (6B3) |
| Cell Signaling Technology HSPA1B antibody (Cell Signaling, 4873S) was used in western blot on human samples . Mol Cancer Res (2013) ncbi |
Articles Reviewed
- Mitra S, Ghosh B, Gayen N, Roy J, Mandal A. Bipartite Role of Heat Shock Protein 90 (Hsp90) Keeps CRAF Kinase Poised for Activation. J Biol Chem. 2016;291:24579-24593 pubmed
- de la Fuente S, Fernandez Sanz C, Vail C, Agra E, Holmström K, Sun J, et al. Strategic Positioning and Biased Activity of the Mitochondrial Calcium Uniporter in Cardiac Muscle. J Biol Chem. 2016;291:23343-23362 pubmed
- BRANDT C, McFie P, Stone S. Diacylglycerol acyltransferase-2 and monoacylglycerol acyltransferase-2 are ubiquitinated proteins that are degraded by the 26S proteasome. Biochem J. 2016;473:3621-3637 pubmed
- Frohwitter G, Buerger H, van Diest P, Korsching E, Kleinheinz J, Fillies T. Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways. Oncol Lett. 2016;12:107-113 pubmed
- Schmitz M, Douxfils J, Mandiki S, Morana C, Baekelandt S, Kestemont P. Chronic hyperosmotic stress interferes with immune homeostasis in striped catfish (Pangasianodon hypophthalmus, S.) and leads to excessive inflammatory response during bacterial infection. Fish Shellfish Immunol. 2016;55:550-8 pubmed publisher
- Zheng G, Li N, Jia X, Peng C, Luo L, Deng Y, et al. MYCN-mediated miR-21 overexpression enhances chemo-resistance via targeting CADM1 in tongue cancer. J Mol Med (Berl). 2016;94:1129-1141 pubmed
- Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, et al. Dendritic cells combined with doxorubicin induces immunogenic cell death and exhibits antitumor effects for osteosarcoma. Oncol Lett. 2016;11:2169-2175 pubmed
- Gao S, Chen X, Jin H, Ren S, Liu Z, Fang X, et al. Overexpression of ErbB2 renders breast cancer cells susceptible to 3-BrPA through the increased dissociation of hexokinase II from mitochondrial outer membrane. Oncol Lett. 2016;11:1567-1573 pubmed
- Stanojlović M, Guševac I, Grković I, Zlatković J, Mitrović N, Zarić M, et al. Effects of chronic cerebral hypoperfusion and low-dose progesterone treatment on apoptotic processes, expression and subcellular localization of key elements within Akt and Erk signaling pathways in rat hippocampus. Neuroscience. 2015;311:308-21 pubmed publisher
- Tsai Y, Lai C, Lai C, Chang K, Wu K, Tseng S, et al. The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth. Oncotarget. 2014;5:6425-36 pubmed
- Irvine M, Philipsz S, Frausto M, Mijatov B, Gallagher S, Fung C, et al. Amino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondria. Cell Cycle. 2010;9:829-39 pubmed
- Blank M, Bastrop R, Jürss K. Stress protein response in two sibling species of Marenzelleria (Polychaeta: Spionidae): is there an influence of acclimation salinity?. Comp Biochem Physiol B Biochem Mol Biol. 2006;144:451-62 pubmed
- Krauss M, Haucke V. Functional assay of effectors of ADP ribosylation factor 6 during clathrin/AP-2 coat recruitment to membranes. Methods Enzymol. 2005;404:388-98 pubmed
- Desagher S, Osen Sand A, Nichols A, Eskes R, Montessuit S, Lauper S, et al. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. J Cell Biol. 1999;144:891-901 pubmed
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