This is a Validated Antibody Database (VAD) review about human HRPT2, based on 6 published articles (read how Labome selects the articles), using HRPT2 antibody in all methods. It is aimed to help Labome visitors find the most suited HRPT2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HRPT2 synonym: C1orf28; FIHP; HPTJT; HRPT1; HRPT2; HYX; parafibromin; Paf1/RNA polymerase II complex component; cell division cycle 73 Paf1/RNA polymerase II complex component-like protein; cell division cycle 73, Paf1/RNA polymerase II complex component, homolog; cell division cycle protein 73 homolog; hyperparathyroidism 2 protein

Knockout validation
Bethyl
rabbit polyclonal
  • immunoprecipitation; human; fig 1b
  • western blot; human; 1:1000; fig 1b
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2j
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 6e
Bethyl HRPT2 antibody (Bethyl, A300-170A) was used in immunoprecipitation on human samples (fig 1b), in western blot on human samples at 1:1000 (fig 1b), in western blot knockout validation on mouse samples at 1:1000 (fig 2j) and in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 6e). Nat Commun (2016) ncbi
Bethyl
rabbit polyclonal
  • immunoprecipitation; human; fig 1b
  • western blot; human; 1:1000; fig 1b
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2j
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 6e
Bethyl HRPT2 antibody (Bethyl, A300-170A) was used in immunoprecipitation on human samples (fig 1b), in western blot on human samples at 1:1000 (fig 1b), in western blot knockout validation on mouse samples at 1:1000 (fig 2j) and in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 6e). Nat Commun (2016) ncbi
rabbit polyclonal
  • ChIP-Seq; mouse; fig 2
Bethyl HRPT2 antibody (Bethyl, A300-170A) was used in ChIP-Seq on mouse samples (fig 2). PLoS Genet (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Bethyl HRPT2 antibody (Bethyl Laboratories, A300-170A) was used in western blot on human samples (fig 2). Biochem Biophys Res Commun (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (2H1)
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3c
In order to investigate the role of Wnt4 in zona glomerulosa differentiation, Santa Cruz Biotechnology HRPT2 antibody (SantaCruz, SC-33638) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 3c). Nat Commun (2016) ncbi
mouse monoclonal (2H1)
  • western blot; human; fig 1c
Santa Cruz Biotechnology HRPT2 antibody (Santa Cruz, sc-33638) was used in western blot on human samples (fig 1c). Mol Cell Biol (2015) ncbi
Invitrogen
rabbit polyclonal
  • western blot; mouse; loading ...
In order to show that Eros is essential for host defense via the phagocyte NAPDH oxidase, Invitrogen HRPT2 antibody (Thermo Fisher Scientific, PA5-17159) was used in western blot on mouse samples . J Exp Med (2017) ncbi
Articles Reviewed
  1. Thomas D, Clare S, Sowerby J, Pardo M, Juss J, Goulding D, et al. Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity. J Exp Med. 2017;214:1111-1128 pubmed publisher
  2. Kikuchi I, Takahashi Kanemitsu A, Sakiyama N, Tang C, Tang P, Noda S, et al. Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways. Nat Commun. 2016;7:12887 pubmed publisher
  3. Drelon C, Berthon A, Sahut Barnola I, Mathieu M, Dumontet T, Rodriguez S, et al. PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development. Nat Commun. 2016;7:12751 pubmed publisher
  4. Yang Y, Li W, Hoque M, Hou L, Shen S, Tian B, et al. PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation. PLoS Genet. 2016;12:e1005794 pubmed publisher
  5. Noda S, Takahashi A, Hayashi T, Tanuma S, Hatakeyama M. Determination of the catalytic activity of LEOPARD syndrome-associated SHP2 mutants toward parafibromin, a bona fide SHP2 substrate involved in Wnt signaling. Biochem Biophys Res Commun. 2016;469:1133-9 pubmed publisher
  6. Cao Q, Yamamoto J, Isobe T, Tateno S, Murase Y, Chen Y, et al. Characterization of the Human Transcription Elongation Factor Rtf1: Evidence for Nonoverlapping Functions of Rtf1 and the Paf1 Complex. Mol Cell Biol. 2015;35:3459-70 pubmed publisher