This is a Validated Antibody Database (VAD) review about human HPRT1, based on 10 published articles (read how Labome selects the articles), using HPRT1 antibody in all methods. It is aimed to help Labome visitors find the most suited HPRT1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HPRT1 synonym: HGPRT; HPRT; hypoxanthine-guanine phosphoribosyltransferase; HGPRTase; hypoxanthine-guanine phosphoribosyltransferase 1; testicular tissue protein Li 89

Abcam
rabbit monoclonal (EPR5299)
  • western blot; human; 1:10,000; loading ...; fig s1d
In order to understand the contribution of floor-plate-derived netrin-1 to commissural axon guidance, Abcam HPRT1 antibody (Abcam, ab109021) was used in western blot on human samples at 1:10,000 (fig s1d). Nature (2017) ncbi
rabbit polyclonal
  • western blot; rat; fig 1
Abcam HPRT1 antibody (Abcam, ab10479) was used in western blot on rat samples (fig 1). Sci Rep (2016) ncbi
rabbit monoclonal (EPR5299)
  • western blot; mouse
In order to assess the role of receptor-interacting protein 2 in VEGF signalling and myocardial ischaemia/reperfusion injury, Abcam HPRT1 antibody (Abcam, ab109021) was used in western blot on mouse samples . Cardiovasc Res (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Abcam HPRT1 antibody (Abcam, ab10479) was used in western blot on mouse samples . PLoS ONE (2013) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3
Abcam HPRT1 antibody (Abcam, ab10479) was used in western blot on mouse samples (fig 3). PLoS Genet (2013) ncbi
rabbit polyclonal
  • western blot; dog; 1:1000
Abcam HPRT1 antibody (Abcam, ab10479) was used in western blot on dog samples at 1:1000. Mol Pharmacol (2013) ncbi
rabbit monoclonal (EPR5299)
  • western blot; mouse; fig 4
Abcam HPRT1 antibody (Abcam, ab109021) was used in western blot on mouse samples (fig 4). PLoS ONE (2012) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-1)
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology HPRT1 antibody (Santa Cruz, sc-376938) was used in western blot on human samples (fig 2a). J Cell Physiol (2017) ncbi
mouse monoclonal (F-1)
  • western blot; mouse; fig 2b
In order to investigate the impact of ORMDL3 to the mast cell physiology, Santa Cruz Biotechnology HPRT1 antibody (Santa Cruz, sc-376938) was used in western blot on mouse samples (fig 2b). Cell Mol Life Sci (2016) ncbi
Invitrogen
mouse monoclonal (1F8D11)
  • flow cytometry; human; loading ...; fig 1c
  • immunocytochemistry; human; loading ...; fig 4a
  • immunohistochemistry; human; loading ...; fig 7b
In order to investigate the role of salvage pathway in lung cancer, Invitrogen HPRT1 antibody (Thermo Fisher Scientific, 1F8D11) was used in flow cytometry on human samples (fig 1c), in immunocytochemistry on human samples (fig 4a) and in immunohistochemistry on human samples (fig 7b). Onco Targets Ther (2017) ncbi
Articles Reviewed
  1. Dominici C, Moreno Bravo J, Puiggros S, Rappeneau Q, Rama N, Vieugué P, et al. Floor-plate-derived netrin-1 is dispensable for commissural axon guidance. Nature. 2017;545:350-354 pubmed publisher
  2. Townsend M, Anderson M, Weagel E, Velazquez E, Weber K, Robison R, et al. Non-small-cell lung cancer cell lines A549 and NCI-H460 express hypoxanthine guanine phosphoribosyltransferase on the plasma membrane. Onco Targets Ther. 2017;10:1921-1932 pubmed publisher
  3. Squillaro T, Antonucci I, Alessio N, Esposito A, Cipollaro M, Melone M, et al. Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes. J Cell Physiol. 2017;232:3454-3467 pubmed publisher
  4. Meek S, Thomson A, Sutherland L, Sharp M, Thomson J, Bishop V, et al. Reduced levels of dopamine and altered metabolism in brains of HPRT knock-out rats: a new rodent model of Lesch-Nyhan Disease. Sci Rep. 2016;6:25592 pubmed publisher
  5. Bugajev V, Hálová I, Dráberová L, Bambousková M, Potůčková L, Draberova H, et al. Negative regulatory roles of ORMDL3 in the FcεRI-triggered expression of proinflammatory mediators and chemotactic response in murine mast cells. Cell Mol Life Sci. 2016;73:1265-85 pubmed publisher
  6. Andersson L, Scharin Täng M, Lundqvist A, Lindbom M, Mardani I, Fogelstrand P, et al. Rip2 modifies VEGF-induced signalling and vascular permeability in myocardial ischaemia. Cardiovasc Res. 2015;107:478-86 pubmed publisher
  7. Jamsai D, Clark B, Smith S, Whittle B, Goodnow C, Ormandy C, et al. A missense mutation in the transcription factor ETV5 leads to sterility, increased embryonic and perinatal death, postnatal growth restriction, renal asymmetry and polydactyly in the mouse. PLoS ONE. 2013;8:e77311 pubmed publisher
  8. O Bryan M, Clark B, McLaughlin E, D Sylva R, O Donnell L, Wilce J, et al. RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility. PLoS Genet. 2013;9:e1003628 pubmed publisher
  9. Naesens L, Guddat L, Keough D, van Kuilenburg A, Meijer J, Vande Voorde J, et al. Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir). Mol Pharmacol. 2013;84:615-29 pubmed publisher
  10. Nagpal P, Plant P, Correa J, Bain A, Takeda M, Kawabe H, et al. The ubiquitin ligase Nedd4-1 participates in denervation-induced skeletal muscle atrophy in mice. PLoS ONE. 2012;7:e46427 pubmed publisher