This is a Validated Antibody Database (VAD) review about human HNRNPK, based on 32 published articles (read how Labome selects the articles), using HNRNPK antibody in all methods. It is aimed to help Labome visitors find the most suited HNRNPK antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HNRNPK synonym: AUKS; CSBP; HNRPK; TUNP

Abcam
mouse monoclonal (F45 P9 C7)
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 3b
Abcam HNRNPK antibody (Abcam, Ab23644) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 3b). Acta Neuropathol (2021) ncbi
mouse monoclonal (F45 P9 C7)
  • immunocytochemistry; human; loading ...; fig 5a
Abcam HNRNPK antibody (Abcam, ab204456) was used in immunocytochemistry on human samples (fig 5a). Molecules (2021) ncbi
domestic rabbit monoclonal (EP943Y)
  • western blot; mouse; 1:10,000; fig s2
Abcam HNRNPK antibody (Abcam, ab52600) was used in western blot on mouse samples at 1:10,000 (fig s2). J Biol Chem (2021) ncbi
mouse monoclonal (F45 P9 C7)
  • immunocytochemistry; human; loading ...; fig 4
Abcam HNRNPK antibody (Abcam, ab204456) was used in immunocytochemistry on human samples (fig 4). Front Cell Dev Biol (2020) ncbi
mouse monoclonal (F45 P9 C7)
  • western blot; mouse; 1:1000; loading ...; fig 4a
Abcam HNRNPK antibody (Abcam, ab23644) was used in western blot on mouse samples at 1:1000 (fig 4a). Hum Mol Genet (2018) ncbi
domestic rabbit monoclonal (EP943Y)
  • western blot; mouse; 1:10,000; fig 6
Abcam HNRNPK antibody (Abcam, ab52600) was used in western blot on mouse samples at 1:10,000 (fig 6). PLoS ONE (2016) ncbi
mouse monoclonal (F45 P9 C7)
  • immunoprecipitation; human; fig 3b
  • immunocytochemistry; human; fig 3b
  • western blot; human; fig 3b
Abcam HNRNPK antibody (Abcam, ab23644) was used in immunoprecipitation on human samples (fig 3b), in immunocytochemistry on human samples (fig 3b) and in western blot on human samples (fig 3b). J Transl Med (2015) ncbi
domestic rabbit monoclonal (EP943Y)
  • immunohistochemistry - paraffin section; human; loading ...; fig 3
Abcam HNRNPK antibody (Abcam, ab52600) was used in immunohistochemistry - paraffin section on human samples (fig 3). Acta Neuropathol (2015) ncbi
mouse monoclonal (F45 P9 C7)
  • immunohistochemistry - paraffin section; human; 1:5000; fig st1
Abcam HNRNPK antibody (Abcam, ab23644) was used in immunohistochemistry - paraffin section on human samples at 1:5000 (fig st1). Oncogenesis (2015) ncbi
domestic rabbit monoclonal (EP943Y)
  • western blot; human; fig 6b
In order to investigate the function of the alanine repeat-containing C-terminal domain of RNA-binding motif protein 4, Abcam HNRNPK antibody (Abcam, ab52600) was used in western blot on human samples (fig 6b). Nucleic Acids Res (2014) ncbi
domestic rabbit monoclonal (EP943Y)
  • western blot; pigs ; 1:500
In order to study hepatitis E pathogenesis and virulence mechanisms, Abcam HNRNPK antibody (Abcam, ab52600) was used in western blot on pigs samples at 1:500. J Virol (2015) ncbi
mouse monoclonal (F45 P9 C7)
  • immunohistochemistry - paraffin section; human; 1:5000
Abcam HNRNPK antibody (Abcam, ab23644) was used in immunohistochemistry - paraffin section on human samples at 1:5000. Int J Cancer (2014) ncbi
mouse monoclonal (3C2)
  • western blot; human
Abcam HNRNPK antibody (Abcam, ab39975) was used in western blot on human samples . Mol Cell Proteomics (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F45 P9 C7)
  • immunocytochemistry; human; loading ...; fig s4g
  • western blot; human; 1:1000; loading ...; fig s4f
Santa Cruz Biotechnology HNRNPK antibody (Santa cruz, sc53620) was used in immunocytochemistry on human samples (fig s4g) and in western blot on human samples at 1:1000 (fig s4f). Nat Commun (2021) ncbi
mouse monoclonal (3C2)
  • western blot; human; 1:10,000; loading ...; fig 5a
Santa Cruz Biotechnology HNRNPK antibody (Santa Cruz Biotechnology, 32307) was used in western blot on human samples at 1:10,000 (fig 5a). Front Mol Biosci (2020) ncbi
mouse monoclonal (D-6)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
  • immunoprecipitation; human; loading ...; fig 3a
  • immunocytochemistry; human; loading ...; fig 4b
  • western blot; human; loading ...; fig 5a
Santa Cruz Biotechnology HNRNPK antibody (Santa Cruz, sc-28) was used in immunohistochemistry - paraffin section on human samples (fig 1a), in immunoprecipitation on human samples (fig 3a), in immunocytochemistry on human samples (fig 4b) and in western blot on human samples (fig 5a). BMC Cancer (2019) ncbi
mouse monoclonal (D-6)
  • western blot; human; loading ...; fig s5a
In order to investigate the role of ILF2 in RNA splicing and DNA damage response in multiple myeloma, Santa Cruz Biotechnology HNRNPK antibody (Santa Cruz, sc-28380) was used in western blot on human samples (fig s5a). Cancer Cell (2017) ncbi
mouse monoclonal (3C2)
  • western blot; human; loading ...; fig 2b
Santa Cruz Biotechnology HNRNPK antibody (SantaCruz, sc-32307) was used in western blot on human samples (fig 2b). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (3C2)
  • western blot; human; loading ...; fig 1b
Santa Cruz Biotechnology HNRNPK antibody (Santa cruz, sc-32307) was used in western blot on human samples (fig 1b). Nucleic Acids Res (2017) ncbi
mouse monoclonal (D-6)
  • RNA immunoprecipitation; human; tbl 2
In order to identify factors that promote in MOR mRNA stability, Santa Cruz Biotechnology HNRNPK antibody (SantaCruz, sc-28380) was used in RNA immunoprecipitation on human samples (tbl 2). Gene (2017) ncbi
mouse monoclonal (D-6)
  • immunocytochemistry; human; 1:100; fig 1
  • immunohistochemistry; human; 1:500; fig 6
  • western blot; human; fig 4
Santa Cruz Biotechnology HNRNPK antibody (Santa Cruz, sc-28380) was used in immunocytochemistry on human samples at 1:100 (fig 1), in immunohistochemistry on human samples at 1:500 (fig 6) and in western blot on human samples (fig 4). Sci Rep (2016) ncbi
mouse monoclonal (D-6)
  • western blot; pigs ; loading ...; fig 7c
Santa Cruz Biotechnology HNRNPK antibody (Santa Cruz, D-6) was used in western blot on pigs samples (fig 7c). Mol Neurodegener (2015) ncbi
mouse monoclonal (3C2)
  • immunoprecipitation; human; fig 2
In order to report that autoimmune regulator is induced in human and mouse tumor keratinocytes in a K17-dependent manner and results in Gli2-induced skin tumorigenesis in mice, Santa Cruz Biotechnology HNRNPK antibody (Santa Cruz, SC-32307) was used in immunoprecipitation on human samples (fig 2). Nat Genet (2015) ncbi
mouse monoclonal (D-6)
  • immunocytochemistry; human; fig 7d
  • western blot; human; 1:1000
Santa Cruz Biotechnology HNRNPK antibody (Santa, sc-28380) was used in immunocytochemistry on human samples (fig 7d) and in western blot on human samples at 1:1000. Nature (2014) ncbi
Invitrogen
mouse monoclonal (F45 P9 C7)
  • western blot; mouse; 1:1000; loading ...; fig 2c, e4a
  • western blot; human; 1:1000; loading ...; fig e7c
Invitrogen HNRNPK antibody (Invitrogen, MA1-087) was used in western blot on mouse samples at 1:1000 (fig 2c, e4a) and in western blot on human samples at 1:1000 (fig e7c). Nat Med (2022) ncbi
ImmuQuest
mouse monoclonal (7h2/1)
  • western blot; human; fig 8
ImmuQuest HNRNPK antibody (ImmuQuest, IQ284) was used in western blot on human samples (fig 8). Mol Cell Proteomics (2015) ncbi
mouse monoclonal (1.00E+11)
  • western blot; human; fig 1a
ImmuQuest HNRNPK antibody (ImmuQuest, 10E10) was used in western blot on human samples (fig 1a). Mol Cell Biol (2014) ncbi
mouse monoclonal (7h2/1)
  • western blot; human
In order to study a novel Fanconi anemia subtype in which SLX4 is mutated, ImmuQuest HNRNPK antibody (ImmuQuest, IQ284) was used in western blot on human samples . Nat Genet (2011) ncbi
mouse monoclonal (2G10/3)
  • immunoprecipitation; human
  • western blot; human
In order to study a novel Fanconi anemia subtype in which SLX4 is mutated, ImmuQuest HNRNPK antibody (ImmuQuest, IQ285) was used in immunoprecipitation on human samples and in western blot on human samples . Nat Genet (2011) ncbi
Bio-Rad
mouse monoclonal (F45 P9 C7)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1a
Bio-Rad HNRNPK antibody (Bio-Rad, MCA2622) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1a). Acta Neuropathol (2021) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig e2g
Cell Signaling Technology HNRNPK antibody (Cell Signaling, 4675) was used in western blot on mouse samples at 1:500 (fig e2g). Nat Neurosci (2021) ncbi
domestic rabbit monoclonal (D9A8)
  • western blot; human; loading ...; fig s5a
Cell Signaling Technology HNRNPK antibody (CST, 9081S) was used in western blot on human samples (fig s5a). Oncogenesis (2021) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; 1:4000; fig 4
  • western blot; human; 1:4000; fig 3
Cell Signaling Technology HNRNPK antibody (Cell Signaling, 4675) was used in chromatin immunoprecipitation on human samples at 1:4000 (fig 4) and in western blot on human samples at 1:4000 (fig 3). Nat Commun (2016) ncbi
MBL International
  • RNA immunoprecipitation; human
  • immunocytochemistry; human; 1 ug/ml
  • western blot; human; 0.5 ug/ml
In order to develop reagents to study RNA binding proteins, MBL International HNRNPK antibody (MBLI, RN019P) was used in RNA immunoprecipitation on human samples , in immunocytochemistry on human samples at 1 ug/ml and in western blot on human samples at 0.5 ug/ml. Mol Cell (2016) ncbi
Articles Reviewed
  1. Korobeynikov V, Lyashchenko A, Blanco Redondo B, Jafar Nejad P, Shneider N. Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis. Nat Med. 2022;28:104-116 pubmed publisher
  2. Vacher C, Lacaille H, O Reilly J, Salzbank J, Bakalar D, Sebaoui S, et al. Placental endocrine function shapes cerebellar development and social behavior. Nat Neurosci. 2021;24:1392-1401 pubmed publisher
  3. Ashok C, Ahuja N, Natua S, Mishra J, Samaiya A, Shukla S. E2F1 and epigenetic modifiers orchestrate breast cancer progression by regulating oxygen-dependent ESRP1 expression. Oncogenesis. 2021;10:58 pubmed publisher
  4. Bampton A, Gatt A, Humphrey J, Cappelli S, Bhattacharya D, Foti S, et al. HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing. Acta Neuropathol. 2021;142:609-627 pubmed publisher
  5. Pham T, Liao R, Labaer J, Guo J. Multiplexed In Situ Protein Profiling with High-Performance Cleavable Fluorescent Tyramide. Molecules. 2021;26: pubmed publisher
  6. Zheng F, Chen J, Zhang X, Wang Z, Chen J, Lin X, et al. The HIF-1α antisense long non-coding RNA drives a positive feedback loop of HIF-1α mediated transactivation and glycolysis. Nat Commun. 2021;12:1341 pubmed publisher
  7. Pan Y, Iejima D, Nakayama M, Suga A, Noda T, Kaur I, et al. Binding of Gtf2i-β/δ transcription factors to the ARMS2 gene leads to increased circulating HTRA1 in AMD patients and in vitro. J Biol Chem. 2021;296:100456 pubmed publisher
  8. Liao R, Mondal M, Nazaroff C, Mastroeni D, Coleman P, Labaer J, et al. Highly Sensitive and Multiplexed Protein Imaging With Cleavable Fluorescent Tyramide Reveals Human Neuronal Heterogeneity. Front Cell Dev Biol. 2020;8:614624 pubmed publisher
  9. Sapaly D, Delers P, Coridon J, Salman B, Letourneur F, Dumont F, et al. The Small-Molecule Flunarizine in Spinal Muscular Atrophy Patient Fibroblasts Impacts on the Gemin Components of the SMN Complex and TDP43, an RNA-Binding Protein Relevant to Motor Neuron Diseases. Front Mol Biosci. 2020;7:55 pubmed publisher
  10. Li L, Yan S, Zhang H, Zhang M, Huang G, Chen M. Interaction of hnRNP K with MAP 1B-LC1 promotes TGF-β1-mediated epithelial to mesenchymal transition in lung cancer cells. BMC Cancer. 2019;19:894 pubmed publisher
  11. Pellegrini L, Hauser D, Li Y, Mamais A, Beilina A, Kumaran R, et al. Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice. Hum Mol Genet. 2018;27:3257-3271 pubmed publisher
  12. Marchesini M, Ogoti Y, Fiorini E, Aktaş Samur A, Nezi L, D Anca M, et al. ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma. Cancer Cell. 2017;32:88-100.e6 pubmed publisher
  13. Fei T, Chen Y, Xiao T, Li W, Cato L, Zhang P, et al. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc Natl Acad Sci U S A. 2017;114:E5207-E5215 pubmed publisher
  14. Blank M, Chen S, Poetz F, Schnolzer M, Voit R, Grummt I. SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription. Nucleic Acids Res. 2017;45:2675-2686 pubmed publisher
  15. Hwang C, Wagley Y, Law P, Wei L, Loh H. Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A binding protein (PABP). Gene. 2017;598:113-130 pubmed publisher
  16. Seo J, Singh N, Ottesen E, Sivanesan S, Shishimorova M, Singh R. Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene. PLoS ONE. 2016;11:e0154390 pubmed publisher
  17. Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed publisher
  18. Gao X, Feng J, He Y, Xu F, Fan X, Huang W, et al. hnRNPK inhibits GSK3β Ser9 phosphorylation, thereby stabilizing c-FLIP and contributes to TRAIL resistance in H1299 lung adenocarcinoma cells. Sci Rep. 2016;6:22999 pubmed publisher
  19. Zheng F, Yue C, Li G, He B, Cheng W, Wang X, et al. Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype. Nat Commun. 2016;7:10180 pubmed publisher
  20. Wang G, Yang H, Yan S, Wang C, Liu X, Zhao B, et al. Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain. Mol Neurodegener. 2015;10:42 pubmed publisher
  21. Kumar M, Matta A, Masui O, Srivastava G, Kaur J, Thakar A, et al. Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer. J Transl Med. 2015;13:285 pubmed publisher
  22. Hobbs R, DePianto D, Jacob J, Han M, Chung B, Batazzi A, et al. Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes. Nat Genet. 2015;47:933-8 pubmed publisher
  23. Cooper Knock J, Higginbottom A, Stopford M, Highley J, Ince P, Wharton S, et al. Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy. Acta Neuropathol. 2015;130:63-75 pubmed publisher
  24. Chauhan S, Kaur J, Kumar M, Matta A, Srivastava G, Alyass A, et al. Prediction of recurrence-free survival using a protein expression-based risk classifier for head and neck cancer. Oncogenesis. 2015;4:e147 pubmed publisher
  25. Xiao Z, Chang J, Hendriks I, Sigurðsson J, Olsen J, Vertegaal A. System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability. Mol Cell Proteomics. 2015;14:1419-34 pubmed publisher
  26. Chang S, Chang W, Lu C, Tarn W. Alanine repeats influence protein localization in splicing speckles and paraspeckles. Nucleic Acids Res. 2014;42:13788-98 pubmed publisher
  27. Rogée S, Le Gall M, Chafey P, Bouquet J, Cordonnier N, Frederici C, et al. Quantitative proteomics identifies host factors modulated during acute hepatitis E virus infection in the swine model. J Virol. 2015;89:129-43 pubmed publisher
  28. Fischer Kešo R, Breuninger S, Hofmann S, Henn M, Röhrig T, Ströbel P, et al. Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins. Mol Cell Biol. 2014;34:4244-56 pubmed publisher
  29. Haeusler A, Donnelly C, Periz G, Simko E, Shaw P, Kim M, et al. C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Nature. 2014;507:195-200 pubmed publisher
  30. Kaur J, Matta A, Kak I, Srivastava G, Assi J, Leong I, et al. S100A7 overexpression is a predictive marker for high risk of malignant transformation in oral dysplasia. Int J Cancer. 2014;134:1379-88 pubmed publisher
  31. Fan B, Lu K, Reymond Sutandy F, Chen Y, Konan K, Zhu H, et al. A human proteome microarray identifies that the heterogeneous nuclear ribonucleoprotein K (hnRNP K) recognizes the 5' terminal sequence of the hepatitis C virus RNA. Mol Cell Proteomics. 2014;13:84-92 pubmed publisher
  32. Stoepker C, Hain K, Schuster B, Hilhorst Hofstee Y, Rooimans M, Steltenpool J, et al. SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet. 2011;43:138-41 pubmed publisher