This is a Validated Antibody Database (VAD) review about human HNRNPA1, based on 33 published articles (read how Labome selects the articles), using HNRNPA1 antibody in all methods. It is aimed to help Labome visitors find the most suited HNRNPA1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HNRNPA1 synonym: ALS19; ALS20; HNRPA1; HNRPA1L3; IBMPFD3; UP 1; hnRNP A1; hnRNP-A1

Santa Cruz Biotechnology
mouse monoclonal (4B10)
  • immunohistochemistry; mouse; loading ...; fig s8c
Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, sc-32301) was used in immunohistochemistry on mouse samples (fig s8c). Nat Neurosci (2021) ncbi
mouse monoclonal (4B10)
  • western blot; human; loading ...; fig 4a
Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, sc-32301) was used in western blot on human samples (fig 4a). Theranostics (2021) ncbi
mouse monoclonal (4B10)
  • western blot; human; 1:200; loading ...; fig 4s2a
Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, sc-32301) was used in western blot on human samples at 1:200 (fig 4s2a). elife (2020) ncbi
mouse monoclonal (D-4)
  • western blot; human; loading ...; fig 5b
Santa Cruz Biotechnology HNRNPA1 antibody (SCBT, sc-374526) was used in western blot on human samples (fig 5b). Mol Cell (2019) ncbi
mouse monoclonal (4B10)
  • western blot; human; loading ...; fig s4c
Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, sc-32301) was used in western blot on human samples (fig s4c). Nucleic Acids Res (2018) ncbi
mouse monoclonal (4B10)
  • western blot; human; loading ...; fig s5a
In order to investigate the role of ILF2 in RNA splicing and DNA damage response in multiple myeloma, Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, sc-32301) was used in western blot on human samples (fig s5a). Cancer Cell (2017) ncbi
mouse monoclonal (4B10)
  • western blot; human; 1:1000; loading ...; fig 5
Santa Cruz Biotechnology HNRNPA1 antibody (Santa cruz, 4B10) was used in western blot on human samples at 1:1000 (fig 5). J Mol Biol (2017) ncbi
mouse monoclonal (4B10)
  • western blot; human; loading ...; fig 3a
Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz Biotechnology, sc-32301) was used in western blot on human samples (fig 3a). Genes Dev (2017) ncbi
mouse monoclonal (9H10)
  • western blot; human; 1:2000; loading ...; fig 6
In order to demonstrate that 2Apro activity is required for nuclear localization of 3CD, Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, 56700) was used in western blot on human samples at 1:2000 (fig 6). J Virol (2016) ncbi
mouse monoclonal (4B10)
  • western blot; human; loading ...; fig 9h
In order to investigate alternative RNA splicing of HPV18 pre-mRNAs, Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, 4B10) was used in western blot on human samples (fig 9h). J Virol (2016) ncbi
mouse monoclonal (4B10)
  • immunohistochemistry - paraffin section; human; 1:2000; fig 1
  • western blot; human; 1:2000; fig 1
In order to compare colorectal and gastric cancer and their expression patterns and diagnostic efficacies of SR splicing factors and HNRNPA1, Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz Biotechnology, sc-32301) was used in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 1) and in western blot on human samples at 1:2000 (fig 1). BMC Cancer (2016) ncbi
mouse monoclonal (4B10)
  • western blot; human; loading ...; fig 3e
In order to analyze the different isoforms of human CD46, Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, sc-32301) was used in western blot on human samples (fig 3e). J Biol Chem (2016) ncbi
mouse monoclonal (4B10)
  • cross-linking immunoprecipitation; human; fig 6
  • western blot; human; fig 6
Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, sc-32301) was used in cross-linking immunoprecipitation on human samples (fig 6) and in western blot on human samples (fig 6). Genes Dev (2016) ncbi
mouse monoclonal (4B10)
  • western blot; human; 1:2000; fig 5
Santa Cruz Biotechnology HNRNPA1 antibody (santa Cruz, sc-32301) was used in western blot on human samples at 1:2000 (fig 5). Nat Commun (2016) ncbi
mouse monoclonal (4B10)
  • RNA immunoprecipitation; human
In order to develop reagents to study RNA binding proteins, Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, sc-32301) was used in RNA immunoprecipitation on human samples . Mol Cell (2016) ncbi
mouse monoclonal (4B10)
In order to characterize human osteosarcoma U2OS cells for genome landscape of SRSF3-regulated splicing events and gene expression, Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz Biotechnology, 4B10) was used . Nucleic Acids Res (2016) ncbi
mouse monoclonal (4B10)
  • western blot; human; 1:1000
In order to study the efficacy of (-)-Epicatechin in the prevention of tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity, Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz Biotechnology, sc-32301) was used in western blot on human samples at 1:1000. Arch Biochem Biophys (2015) ncbi
mouse monoclonal (F-8)
  • western blot; human
In order to investigate the mechanism for the RNautophagy/DNautophagy effect of LAMP2C, Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, sc-365486) was used in western blot on human samples . Biochem Biophys Res Commun (2015) ncbi
mouse monoclonal (4B10)
  • RNA immunoprecipitation; human; loading ...; fig 6a
Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, sc-32301) was used in RNA immunoprecipitation on human samples (fig 6a). Mol Cancer (2014) ncbi
mouse monoclonal (4B10)
  • immunoprecipitation; human; fig 4
Santa Cruz Biotechnology HNRNPA1 antibody (Santa Cruz, sc-32301) was used in immunoprecipitation on human samples (fig 4). ACS Chem Biol (2014) ncbi
Abcam
domestic rabbit monoclonal (EPR12768)
  • immunocytochemistry; human; loading ...; fig 5a
Abcam HNRNPA1 antibody (Abcam, ab198535) was used in immunocytochemistry on human samples (fig 5a). Molecules (2021) ncbi
domestic rabbit monoclonal (EPR12768)
  • immunocytochemistry; human; loading ...; fig 4
Abcam HNRNPA1 antibody (Abcam, ab198535) was used in immunocytochemistry on human samples (fig 4). Front Cell Dev Biol (2020) ncbi
domestic rabbit monoclonal (EPR12768)
  • western blot; human; fig 5b
Abcam HNRNPA1 antibody (Abcam, ab177152) was used in western blot on human samples (fig 5b). Aging (Albany NY) (2019) ncbi
Novus Biologicals
mouse monoclonal (4B10)
  • western blot; human; 1:2000; loading ...; fig s3b
Novus Biologicals HNRNPA1 antibody (Novus Biologicals, NB100-672) was used in western blot on human samples at 1:2000 (fig s3b). Nat Commun (2016) ncbi
mouse monoclonal (4B10)
  • western blot; human; loading ...; fig 2
In order to elucidate how Fused in Sarcoma/Translocated in Liposarcoma contributes to disease, Novus Biologicals HNRNPA1 antibody (Novus, NB100-672) was used in western blot on human samples (fig 2). Biochim Biophys Acta (2016) ncbi
mouse monoclonal (4B10)
  • immunocytochemistry; human; loading ...; fig 7c
  • western blot; human; loading ...; fig 5b
In order to study the translational regulation of sST2, Novus Biologicals HNRNPA1 antibody (Novus Biologicals, NB100-672) was used in immunocytochemistry on human samples (fig 7c) and in western blot on human samples (fig 5b). Biochim Biophys Acta (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; 1:3000; loading ...; fig s1e
In order to study the function of SAF-A in interphase chromosome structure integrity and its mechanism, Invitrogen HNRNPA1 antibody (Invitrogen, PA5-19431) was used in western blot on human samples at 1:3000 (fig s1e). Cell (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D21H11)
  • western blot; human; 1:2000; loading ...; fig 2c
Cell Signaling Technology HNRNPA1 antibody (Cell Signalling, D21H11) was used in western blot on human samples at 1:2000 (fig 2c). Nat Commun (2019) ncbi
domestic rabbit monoclonal (D21H11)
  • flow cytometry; human; 1:30
In order to characterize enhancement of transcriptome variability and metastatic fitness by highly variable cancer subpopulations, Cell Signaling Technology HNRNPA1 antibody (Cell Signalling, D21H11) was used in flow cytometry on human samples at 1:30. Nat Commun (2016) ncbi
domestic rabbit monoclonal (D21H11)
  • western blot; human; fig 5
Cell Signaling Technology HNRNPA1 antibody (Cell Signaling, 8443) was used in western blot on human samples (fig 5). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D21H11)
  • western blot; human; fig 4
Cell Signaling Technology HNRNPA1 antibody (Cell Signaling, 8443) was used in western blot on human samples (fig 4). J Proteome Res (2015) ncbi
domestic rabbit monoclonal (D21H11)
  • immunocytochemistry; hamsters
Cell Signaling Technology HNRNPA1 antibody (Cell Signaling, 8443) was used in immunocytochemistry on hamsters samples . J Virol (2012) ncbi
MilliporeSigma
mouse monoclonal (4B10)
  • western blot; human; 1:8000; loading ...; fig 2a
MilliporeSigma HNRNPA1 antibody (Sigma-Aldrich, 4B10) was used in western blot on human samples at 1:8000 (fig 2a). Acta Neuropathol (2020) ncbi
Articles Reviewed
  1. Pham T, Liao R, Labaer J, Guo J. Multiplexed In Situ Protein Profiling with High-Performance Cleavable Fluorescent Tyramide. Molecules. 2021;26: pubmed publisher
  2. Van Alstyne M, Tattoli I, Delestrée N, Recinos Y, Workman E, Shihabuddin L, et al. Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit. Nat Neurosci. 2021;24:930-940 pubmed publisher
  3. Liao R, Mondal M, Nazaroff C, Mastroeni D, Coleman P, Labaer J, et al. Highly Sensitive and Multiplexed Protein Imaging With Cleavable Fluorescent Tyramide Reveals Human Neuronal Heterogeneity. Front Cell Dev Biol. 2020;8:614624 pubmed publisher
  4. Zhu S, Chen W, Wang J, Qi L, Pan H, Feng Z, et al. SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing. Theranostics. 2021;11:3359-3375 pubmed publisher
  5. Hayes L, Duan L, Bowen K, Kalab P, Rothstein J. C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import. elife. 2020;9: pubmed publisher
  6. Nihei Y, Mori K, Werner G, Arzberger T, Zhou Q, Khosravi B, et al. Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3. Acta Neuropathol. 2020;139:99-118 pubmed publisher
  7. Jia Q, Nie H, Yu P, Xie B, Wang C, Yang F, et al. HNRNPA1-mediated 3' UTR length changes of HN1 contributes to cancer- and senescence-associated phenotypes. Aging (Albany NY). 2019;11:4407-4437 pubmed publisher
  8. Sajini A, Choudhury N, Wagner R, Bornelöv S, Selmi T, Spanos C, et al. Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation. Nat Commun. 2019;10:2550 pubmed publisher
  9. Lee S, Mayr C. Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. Mol Cell. 2019;: pubmed publisher
  10. Liu H, Lorenzini P, Zhang F, Xu S, Wong M, Zheng J, et al. Alternative splicing analysis in human monocytes and macrophages reveals MBNL1 as major regulator. Nucleic Acids Res. 2018;46:6069-6086 pubmed publisher
  11. Marchesini M, Ogoti Y, Fiorini E, Aktaş Samur A, Nezi L, D Anca M, et al. ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma. Cancer Cell. 2017;32:88-100.e6 pubmed publisher
  12. Nozawa R, Boteva L, Soares D, Naughton C, Dun A, Buckle A, et al. SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs. Cell. 2017;169:1214-1227.e18 pubmed publisher
  13. Kumar S, Downie Ruiz Velasco A, Michlewski G. Oleic Acid Induces MiR-7 Processing through Remodeling of Pri-MiR-7/Protein Complex. J Mol Biol. 2017;429:1638-1649 pubmed publisher
  14. Vancevska A, Douglass K, Pfeiffer V, Manley S, Lingner J. The telomeric DNA damage response occurs in the absence of chromatin decompaction. Genes Dev. 2017;31:567-577 pubmed publisher
  15. Hu J, Khodadadi Jamayran A, Mao M, Shah K, Yang Z, Nasim M, et al. AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors. Nat Commun. 2016;7:13347 pubmed publisher
  16. Walker E, Jensen L, Croft S, Wei K, Fulcher A, Jans D, et al. Rhinovirus 16 2A Protease Affects Nuclear Localization of 3CD during Infection. J Virol. 2016;90:11032-11042 pubmed
  17. Ajiro M, Tang S, Doorbar J, Zheng Z. Serine/Arginine-Rich Splicing Factor 3 and Heterogeneous Nuclear Ribonucleoprotein A1 Regulate Alternative RNA Splicing and Gene Expression of Human Papillomavirus 18 through Two Functionally Distinguishable cis Elements. J Virol. 2016;90:9138-52 pubmed publisher
  18. Kamelgarn M, Chen J, Kuang L, Arenas A, Zhai J, Zhu H, et al. Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS. Biochim Biophys Acta. 2016;1862:2004-14 pubmed publisher
  19. Park W, Kim H, Kang D, Ryu J, Choi K, Lee G, et al. Comparative expression patterns and diagnostic efficacies of SR splicing factors and HNRNPA1 in gastric and colorectal cancer. BMC Cancer. 2016;16:358 pubmed publisher
  20. Tang S, Luo S, Ho J, Ly P, Goh E, Roca X. Characterization of the Regulation of CD46 RNA Alternative Splicing. J Biol Chem. 2016;291:14311-23 pubmed publisher
  21. Kunze M, Benz F, Brauß T, Lampe S, Weigand J, Braun J, et al. sST2 translation is regulated by FGF2 via an hnRNP A1-mediated IRES-dependent mechanism. Biochim Biophys Acta. 2016;1859:848-59 pubmed publisher
  22. Geissler R, Simkin A, Floss D, Patel R, Fogarty E, Scheller J, et al. A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1. Genes Dev. 2016;30:1070-85 pubmed publisher
  23. Nguyen A, Yoshida M, Goodarzi H, Tavazoie S. Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness. Nat Commun. 2016;7:11246 pubmed publisher
  24. Parameswaran R, Ramakrishnan P, Moreton S, Xia Z, Hou Y, Lee D, et al. Repression of GSK3 restores NK cell cytotoxicity in AML patients. Nat Commun. 2016;7:11154 pubmed publisher
  25. Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed publisher
  26. Mori F, Ferraiuolo M, Santoro R, Sacconi A, Goeman F, Pallocca M, et al. Multitargeting activity of miR-24 inhibits long-term melatonin anticancer effects. Oncotarget. 2016;7:20532-48 pubmed publisher
  27. Ajiro M, Jia R, Yang Y, Zhu J, Zheng Z. A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells. Nucleic Acids Res. 2016;44:1854-70 pubmed publisher
  28. Berard A, Coombs K, Severini A. Quantification of the host response proteome after herpes simplex virus type 1 infection. J Proteome Res. 2015;14:2121-42 pubmed publisher
  29. Contreras T, Ricciardi E, Cremonini E, Oteiza P. (-)-Epicatechin in the prevention of tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity. Arch Biochem Biophys. 2015;573:84-91 pubmed publisher
  30. Fujiwara Y, Hase K, Wada K, Kabuta T. An RNautophagy/DNautophagy receptor, LAMP2C, possesses an arginine-rich motif that mediates RNA/DNA-binding. Biochem Biophys Res Commun. 2015;460:281-6 pubmed publisher
  31. DERY K, Kujawski M, Grunert D, Wu X, Ngyuen T, Cheung C, et al. IRF-1 regulates alternative mRNA splicing of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in breast epithelial cells generating an immunoreceptor tyrosine-based inhibition motif (ITIM) containing isoform. Mol Cancer. 2014;13:64 pubmed publisher
  32. Rust H, Subramanian V, West G, Young D, Schultz P, Thompson P. Using unnatural amino acid mutagenesis to probe the regulation of PRMT1. ACS Chem Biol. 2014;9:649-55 pubmed publisher
  33. Akhrymuk I, Kulemzin S, Frolova E. Evasion of the innate immune response: the Old World alphavirus nsP2 protein induces rapid degradation of Rpb1, a catalytic subunit of RNA polymerase II. J Virol. 2012;86:7180-91 pubmed publisher