This is a Validated Antibody Database (VAD) review about human HIST2H2AC, based on 36 published articles (read how Labome selects the articles), using HIST2H2AC antibody in all methods. It is aimed to help Labome visitors find the most suited HIST2H2AC antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HIST2H2AC synonym: H2A; H2A-GL101; H2A/q; H2AFQ; histone H2A type 2-C; H2A histone family, member Q; histone 2, H2ac; histone H2A-GL101; histone H2A/q; histone IIa; histone cluster 2, H2ac

Abcam
rabbit monoclonal (EP856Y)
  • western blot; human
Abcam HIST2H2AC antibody (Abcam, ab45152) was used in western blot on human samples . Mol Cell Biochem (2014) ncbi
rabbit monoclonal (EP856Y)
  • chromatin immunoprecipitation; human
  • western blot; human; 1:2000
Abcam HIST2H2AC antibody (Abcam, ab45152) was used in chromatin immunoprecipitation on human samples and in western blot on human samples at 1:2000. Nat Struct Mol Biol (2011) ncbi
Invitrogen
rabbit monoclonal (J.924.2)
  • immunocytochemistry; common tobacco; 1:200; fig 2
In order to study how chromosomal changes contribute to cytomixis, Invitrogen HIST2H2AC antibody (Thermo Scientific, MA5-11195) was used in immunocytochemistry on common tobacco samples at 1:200 (fig 2). Front Plant Sci (2015) ncbi
EMD Millipore
mouse monoclonal (E6C5)
  • western blot; human; 1:5000; loading ...; fig 2f
EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in western blot on human samples at 1:5000 (fig 2f). Nat Cell Biol (2018) ncbi
mouse monoclonal (E6C5)
  • ChIP-Seq; mouse; loading ...; fig 3a
EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in ChIP-Seq on mouse samples (fig 3a). elife (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 1d
EMD Millipore HIST2H2AC antibody (Millipore, 07-146) was used in western blot on human samples at 1:2000 (fig 1d). Nucleic Acids Res (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3B
In order to investigate the role of the PTEN phosphatase in DNA interstrand crosslink repair, EMD Millipore HIST2H2AC antibody (Millipore, 07-146) was used in western blot on human samples (fig 3B). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig s4a
EMD Millipore HIST2H2AC antibody (Millipore, 07-146) was used in western blot on human samples (fig s4a). Nature (2016) ncbi
mouse monoclonal (E6C5)
In order to characterize male XX chromosomes that recombine and undergo pachytene chromatin inactivation as a form of unique sex chromosome systems in Ellobius, EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used . Sci Rep (2016) ncbi
mouse monoclonal (E6C5)
  • chromatin immunoprecipitation; human; loading ...; fig st3
In order to study the contribution of SFMBT2 to prostate cancer metastasis, EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in chromatin immunoprecipitation on human samples (fig st3). Oncotarget (2016) ncbi
mouse monoclonal (E6C5)
  • immunocytochemistry; rat; 1:100; fig 2
  • western blot; rat; 1:1000; fig 2
EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in immunocytochemistry on rat samples at 1:100 (fig 2) and in western blot on rat samples at 1:1000 (fig 2). Acta Neuropathol Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; fig s1
EMD Millipore HIST2H2AC antibody (Merck Millipore, 07-146) was used in western blot on human samples (fig s1). PLoS Genet (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:5000; fig 4
EMD Millipore HIST2H2AC antibody (Millipore, 07-146) was used in western blot on human samples at 1:5000 (fig 4). Nat Genet (2016) ncbi
mouse monoclonal (E6C5)
  • immunocytochemistry; human; fig 5
EMD Millipore HIST2H2AC antibody (Millipore, 05-C678) was used in immunocytochemistry on human samples (fig 5). Nucleic Acids Res (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 4
EMD Millipore HIST2H2AC antibody (Millipore, 07-146) was used in western blot on human samples (fig 4). Nature (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2
In order to elucidate the regulation and dynamics of H2A-T120 phosphorylation by Bub1, EMD Millipore HIST2H2AC antibody (Millipore, 07-146) was used in western blot on human samples (fig 2). Nat Commun (2015) ncbi
mouse monoclonal (E6C5)
  • western blot; mouse; fig 1a
EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in western blot on mouse samples (fig 1a). EMBO J (2015) ncbi
rabbit polyclonal
  • western blot; human; fig s10
In order to identify proteins associated with EBNA3A, EBNA3B, and EBNA3C in lymphoblastoid cells, EMD Millipore HIST2H2AC antibody (Millipore, #07-146) was used in western blot on human samples (fig s10). PLoS Pathog (2015) ncbi
mouse monoclonal (E6C5)
  • chromatin immunoprecipitation; human; fig s10
In order to identify proteins associated with EBNA3A, EBNA3B, and EBNA3C in lymphoblastoid cells, EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in chromatin immunoprecipitation on human samples (fig s10). PLoS Pathog (2015) ncbi
mouse monoclonal (E6C5)
  • chromatin immunoprecipitation; mouse
In order to examine the association of the FBXL10/KDM2B scaffolding protein with novel polycomb repressive complex-1 and its role in adipogenesis, EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in chromatin immunoprecipitation on mouse samples . J Biol Chem (2015) ncbi
mouse monoclonal (E6C5)
  • western blot; fruit fly; 1:250
EMD Millipore HIST2H2AC antibody (Merck, E6C5) was used in western blot on fruit fly samples at 1:250. PLoS ONE (2014) ncbi
mouse monoclonal (E6C5)
  • western blot; human
EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in western blot on human samples . J Biol Chem (2014) ncbi
mouse monoclonal (E6C5)
  • western blot; human
EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in western blot on human samples . Oncotarget (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 0.5 ug/mL
In order to study the effect of the freshwater cyanotoxin cylindrospermopsin on chromatin remodelling, EMD Millipore HIST2H2AC antibody (Millipore, 07-290) was used in immunocytochemistry on human samples at 0.5 ug/mL. PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human
EMD Millipore HIST2H2AC antibody (Millipore, 07-290) was used in western blot on human samples . Mol Cell Biochem (2014) ncbi
mouse monoclonal (E6C5)
  • chromatin immunoprecipitation; human
  • western blot; human; 1:500
In order to study the Involvement of EED in the organization of polycomb group complexes, EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in chromatin immunoprecipitation on human samples and in western blot on human samples at 1:500. Nat Commun (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:5000
In order to study the Involvement of EED in the organization of polycomb group complexes, EMD Millipore HIST2H2AC antibody (Millipore, 07-146) was used in western blot on human samples at 1:5000. Nat Commun (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
In order to investigate the murine tau isoforms in brain and peripheral organs, EMD Millipore HIST2H2AC antibody (Millipore, 07-146) was used in western blot on mouse samples at 1:1000. PLoS ONE (2013) ncbi
rabbit polyclonal
  • western blot; human
In order to study the role of an amino terminal FANCD2 nuclear localization signal in the coordinated nuclear localization of both FANCD2 and FANCI, EMD Millipore HIST2H2AC antibody (Millipore, 07-146) was used in western blot on human samples . PLoS ONE (2013) ncbi
mouse monoclonal (E6C5)
  • chromatin immunoprecipitation; human
  • chromatin immunoprecipitation; mouse
EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in chromatin immunoprecipitation on human samples and in chromatin immunoprecipitation on mouse samples . J Clin Invest (2013) ncbi
mouse monoclonal (E6C5)
  • immunocytochemistry; human
  • western blot; human
EMD Millipore HIST2H2AC antibody (EMB Millipore, 05-678) was used in immunocytochemistry on human samples and in western blot on human samples . Cell Cycle (2014) ncbi
mouse monoclonal (E6C5)
  • western blot; human
EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in western blot on human samples . J Biol Chem (2013) ncbi
mouse monoclonal (E6C5)
  • western blot; human
EMD Millipore HIST2H2AC antibody (Millipore, E6C5) was used in western blot on human samples . Nucleic Acids Res (2013) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
EMD Millipore HIST2H2AC antibody (Millipore, 07-146) was used in western blot on mouse samples at 1:1000. J Biol Chem (2013) ncbi
rabbit polyclonal
  • western blot; malaria parasite P. falciparum; 1:1000
EMD Millipore HIST2H2AC antibody (Millipore, 07-146) was used in western blot on malaria parasite P. falciparum samples at 1:1000. Mol Microbiol (2013) ncbi
rabbit polyclonal
  • western blot; human
EMD Millipore HIST2H2AC antibody (Millipore, 07-146) was used in western blot on human samples . Mech Ageing Dev (2012) ncbi
mouse monoclonal (E6C5)
  • immunocytochemistry; mouse; loading ...; fig s3j
EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in immunocytochemistry on mouse samples (fig s3j). Dev Cell (2012) ncbi
mouse monoclonal (E6C5)
  • western blot; mouse
EMD Millipore HIST2H2AC antibody (Millipore, 05-678) was used in western blot on mouse samples . Mol Cell Biol (2010) ncbi
mouse monoclonal (E6C5)
  • immunocytochemistry; mouse; 1:100
EMD Millipore HIST2H2AC antibody (Upstate, E6C5) was used in immunocytochemistry on mouse samples at 1:100. Development (2007) ncbi
Articles Reviewed
  1. Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, et al. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nat Cell Biol. 2018;20:1181-1192 pubmed publisher
  2. Endoh M, Endo T, Shinga J, Hayashi K, Farcas A, Ma K, et al. PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes. elife. 2017;6: pubmed publisher
  3. Maskey R, Flatten K, Sieben C, Peterson K, Baker D, Nam H, et al. Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis. Nucleic Acids Res. 2017;45:4564-4576 pubmed publisher
  4. Vuono E, Mukherjee A, Vierra D, Adroved M, Hodson C, Deans A, et al. The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair. Sci Rep. 2016;6:36439 pubmed publisher
  5. Wang D, Kon N, Lasso G, Jiang L, Leng W, Zhu W, et al. Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode. Nature. 2016;538:118-122 pubmed publisher
  6. Matveevsky S, Bakloushinskaya I, Kolomiets O. Unique sex chromosome systems in Ellobius: How do male XX chromosomes recombine and undergo pachytene chromatin inactivation?. Sci Rep. 2016;6:29949 pubmed publisher
  7. Gwak J, Shin J, Lee K, Hong S, Oh S, Goh S, et al. SFMBT2 (Scm-like with four mbt domains 2) negatively regulates cell migration and invasion in prostate cancer cells. Oncotarget. 2016;7:48250-48264 pubmed publisher
  8. Mata Garrido J, Casafont I, Tapia O, Berciano M, Lafarga M. Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterization. Acta Neuropathol Commun. 2016;4:41 pubmed publisher
  9. Byrd P, Stewart G, Smith A, Eaton C, Taylor A, Guy C, et al. A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development. PLoS Genet. 2016;12:e1005945 pubmed publisher
  10. Harley M, Murina O, Leitch A, Higgs M, Bicknell L, Yigit G, et al. TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism. Nat Genet. 2016;48:36-43 pubmed publisher
  11. Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res. 2016;44:1161-78 pubmed publisher
  12. Mursalimov S, Permyakova N, Deineko E, Houben A, Demidov D. Cytomixis doesn't induce obvious changes in chromatin modifications and programmed cell death in tobacco male meiocytes. Front Plant Sci. 2015;6:846 pubmed publisher
  13. Thorslund T, Ripplinger A, Hoffmann S, Wild T, Uckelmann M, Villumsen B, et al. Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage. Nature. 2015;527:389-93 pubmed publisher
  14. Asghar A, Lajeunesse A, Dulla K, Combes G, Thebault P, Nigg E, et al. Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation. Nat Commun. 2015;6:8364 pubmed publisher
  15. Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, et al. The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination. EMBO J. 2015;34:2885-902 pubmed publisher
  16. Ohashi M, Holthaus A, Calderwood M, Lai C, Krastins B, Sarracino D, et al. The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth. PLoS Pathog. 2015;11:e1004822 pubmed publisher
  17. Inagaki T, Iwasaki S, Matsumura Y, Kawamura T, Tanaka T, Abe Y, et al. The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis. J Biol Chem. 2015;290:4163-77 pubmed publisher
  18. Fereres S, Simón R, Mohd Sarip A, Verrijzer C, Busturia A. dRYBP counteracts chromatin-dependent activation and repression of transcription. PLoS ONE. 2014;9:e113255 pubmed publisher
  19. Hock A, Vigneron A, Vousden K. Ubiquitin-specific peptidase 42 (USP42) functions to deubiquitylate histones and regulate transcriptional activity. J Biol Chem. 2014;289:34862-70 pubmed publisher
  20. Putiri E, Tiedemann R, Liu C, Choi J, Robertson K. Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome. Oncotarget. 2014;5:6338-52 pubmed
  21. Huguet A, Hatton A, Villot R, Quenault H, Blanchard Y, Fessard V. Modulation of chromatin remodelling induced by the freshwater cyanotoxin cylindrospermopsin in human intestinal caco-2 cells. PLoS ONE. 2014;9:e99121 pubmed publisher
  22. Tafrova J, Tafrov S. Human histone acetyltransferase 1 (Hat1) acetylates lysine 5 of histone H2A in vivo. Mol Cell Biochem. 2014;392:259-72 pubmed publisher
  23. Cao Q, Wang X, Zhao M, Yang R, Malik R, Qiao Y, et al. The central role of EED in the orchestration of polycomb group complexes. Nat Commun. 2014;5:3127 pubmed publisher
  24. Liu C, Götz J. Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus. PLoS ONE. 2013;8:e84849 pubmed publisher
  25. Boisvert R, Rego M, Azzinaro P, Mauro M, Howlett N. Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal. PLoS ONE. 2013;8:e81387 pubmed publisher
  26. Zhou J, Dhawan S, Fu H, Snyder E, Bottino R, Kundu S, et al. Combined modulation of polycomb and trithorax genes rejuvenates ? cell replication. J Clin Invest. 2013;123:4849-58 pubmed
  27. Sharma N, Zhu Q, Wani G, He J, Wang Q, Wani A. USP3 counteracts RNF168 via deubiquitinating H2A and ?H2AX at lysine 13 and 15. Cell Cycle. 2014;13:106-14 pubmed publisher
  28. Yuan G, Ma B, Yuan W, Zhang Z, Chen P, Ding X, et al. Histone H2A ubiquitination inhibits the enzymatic activity of H3 lysine 36 methyltransferases. J Biol Chem. 2013;288:30832-42 pubmed publisher
  29. Sy S, Jiang J, O W, Deng Y, Huen M. The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks. Nucleic Acids Res. 2013;41:8572-80 pubmed publisher
  30. Rass E, Chandramouly G, Zha S, Alt F, Xie A. Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells. J Biol Chem. 2013;288:7086-95 pubmed publisher
  31. Hoeijmakers W, Salcedo Amaya A, Smits A, Fran oijs K, Treeck M, Gilberger T, et al. H2A.Z/H2B.Z double-variant nucleosomes inhabit the AT-rich promoter regions of the Plasmodium falciparum genome. Mol Microbiol. 2013;87:1061-73 pubmed publisher
  32. Lee K, Lau Z, Meredith C, Park J. Decrease of p400 ATPase complex and loss of H2A.Z within the p21 promoter occur in senescent IMR-90 human fibroblasts. Mech Ageing Dev. 2012;133:686-94 pubmed publisher
  33. Modzelewski A, Holmes R, Hilz S, Grimson A, Cohen P. AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germline. Dev Cell. 2012;23:251-64 pubmed publisher
  34. Egelhofer T, Minoda A, Klugman S, Lee K, Kolasinska Zwierz P, Alekseyenko A, et al. An assessment of histone-modification antibody quality. Nat Struct Mol Biol. 2011;18:91-3 pubmed publisher
  35. Li X, Corsa C, Pan P, Wu L, Ferguson D, Yu X, et al. MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1. Mol Cell Biol. 2010;30:5335-47 pubmed publisher
  36. Takada Y, Isono K, Shinga J, Turner J, Kitamura H, Ohara O, et al. Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes. Development. 2007;134:579-90 pubmed