This is a Validated Antibody Database (VAD) review about human HIST1H2BO, based on 15 published articles (read how Labome selects the articles), using HIST1H2BO antibody in all methods. It is aimed to help Labome visitors find the most suited HIST1H2BO antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HIST1H2BO synonym: H2B.2; H2B/n; H2BFN; dJ193B12.2; histone H2B type 1-O; H2B histone family, member N; histone 1, H2bo; histone H2B.2; histone H2B.n; histone cluster 1, H2bo

Active Motif
mouse monoclonal (56)
  • chromatin immunoprecipitation; fission yeast; fig 1e
Active Motif HIST1H2BO antibody (Active Motif, 39623) was used in chromatin immunoprecipitation on fission yeast samples (fig 1e). elife (2016) ncbi
mouse monoclonal (56)
  • western blot; fission yeast
Active Motif HIST1H2BO antibody (Active Motif, 39623) was used in western blot on fission yeast samples . Mol Cell Biol (2013) ncbi
mouse monoclonal (5HH2-2A8)
  • western blot; human
Active Motif HIST1H2BO antibody (Active Motif, 61037) was used in western blot on human samples . Proc Natl Acad Sci U S A (2013) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human
  • western blot; human
Active Motif HIST1H2BO antibody (Active Motif, 39121) was used in chromatin immunoprecipitation on human samples and in western blot on human samples . Epigenetics (2011) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human
  • western blot; human
Active Motif HIST1H2BO antibody (Active Motif, 39119) was used in chromatin immunoprecipitation on human samples and in western blot on human samples . Epigenetics (2011) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; 3 ug/time
Active Motif HIST1H2BO antibody (Active Motif, 39121) was used in chromatin immunoprecipitation on human samples at 3 ug/time. Cell Cycle (2010) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; 3 ug/time
Active Motif HIST1H2BO antibody (Active Motif, 39119) was used in chromatin immunoprecipitation on human samples at 3 ug/time. Cell Cycle (2010) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human
In order to study the mechanism for the regulatory function of histone H2B on gene expression and silencing, Active Motif HIST1H2BO antibody (Active Motif, 39125) was used in chromatin immunoprecipitation on human samples . Mol Cell Biol (2010) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human
In order to study the mechanism for the regulatory function of histone H2B on gene expression and silencing, Active Motif HIST1H2BO antibody (Active Motif, 39567) was used in chromatin immunoprecipitation on human samples . Mol Cell Biol (2010) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human
In order to study the mechanism for the regulatory function of histone H2B on gene expression and silencing, Active Motif HIST1H2BO antibody (Active Motif, 39571) was used in chromatin immunoprecipitation on human samples . Mol Cell Biol (2010) ncbi
LifeSpan Biosciences
rabbit polyclonal
  • immunocytochemistry; zebrafish ; 1:100; fig s1
  • western blot; zebrafish ; 1:500; fig s1
LifeSpan Biosciences HIST1H2BO antibody (LifeSpan BioSciences, LS-B2035) was used in immunocytochemistry on zebrafish samples at 1:100 (fig s1) and in western blot on zebrafish samples at 1:500 (fig s1). Sci Rep (2016) ncbi
Cell Signaling Technology
mouse monoclonal (53H3)
  • western blot; mouse; 1:2000; loading ...; fig 4e
Cell Signaling Technology HIST1H2BO antibody (Cell Signaling, 2934) was used in western blot on mouse samples at 1:2000 (fig 4e). Science (2017) ncbi
mouse monoclonal (53H3)
  • western blot; human; loading ...; fig 1c
In order to study the role of ACK1/TNK2 in histone H4 Tyr88-phosphorylation and androgen receptor expression in prostate cancer, Cell Signaling Technology HIST1H2BO antibody (Cell Signaling, 2934) was used in western blot on human samples (fig 1c). Cancer Cell (2017) ncbi
mouse monoclonal (53H3)
  • western blot; human; 1:2000; loading ...; fig 1a
Cell Signaling Technology HIST1H2BO antibody (Cell Signaling, 2934) was used in western blot on human samples at 1:2000 (fig 1a). Nucleic Acids Res (2017) ncbi
mouse monoclonal (53H3)
  • western blot; mouse; loading ...; tbl 1
In order to identify gephyrin as a druggable target for pancreatic beta cell regeneration, Cell Signaling Technology HIST1H2BO antibody (Cell Signaling, 2934) was used in western blot on mouse samples (tbl 1). Cell (2017) ncbi
mouse monoclonal (53H3)
  • western blot; human; loading ...; fig 1d
In order to report the O-linked N-acetylglucosamine glycoproteome observed in human T cells, Cell Signaling Technology HIST1H2BO antibody (Cell Signaling, 2934) was used in western blot on human samples (fig 1d). J Immunol (2016) ncbi
mouse monoclonal (53H3)
  • western blot; mouse; 1:1000; tbl 1
In order to elucidate a deletion of AMP-activated protein kinase in mouse Sertoli cells that modify germ cell quality, Cell Signaling Technology HIST1H2BO antibody (Cell Signalling, 2934) was used in western blot on mouse samples at 1:1000 (tbl 1). Mol Cell Endocrinol (2016) ncbi
mouse monoclonal (53H3)
  • western blot; human
Cell Signaling Technology HIST1H2BO antibody (Cell Signaling Technology, 2934) was used in western blot on human samples . J Biol Chem (2014) ncbi
EMD Millipore
rabbit polyclonal
  • western blot; mouse
EMD Millipore HIST1H2BO antibody (Millipore, AB1623) was used in western blot on mouse samples . Neurobiol Aging (2015) ncbi
Articles Reviewed
  1. Nguyen A, Prado M, Schmidt P, Sendamarai A, Wilson Grady J, Min M, et al. UBE2O remodels the proteome during terminal erythroid differentiation. Science. 2017;357: pubmed publisher
  2. Mahajan K, Malla P, Lawrence H, Chen Z, Kumar Sinha C, Malik R, et al. ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer. Cancer Cell. 2017;31:790-803.e8 pubmed publisher
  3. Chen S, Jing Y, Kang X, Yang L, Wang D, Zhang W, et al. Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Nucleic Acids Res. 2017;45:1144-1158 pubmed publisher
  4. Li J, Casteels T, Frogne T, Ingvorsen C, Honore C, Courtney M, et al. Artemisinins Target GABAA Receptor Signaling and Impair ? Cell Identity. Cell. 2017;168:86-100.e15 pubmed publisher
  5. Lund P, Elias J, Davis M. Global Analysis of O-GlcNAc Glycoproteins in Activated Human T Cells. J Immunol. 2016;197:3086-3098 pubmed
  6. Spiró Z, Koh A, Tay S, See K, Winkler C. Transcriptional enhancement of Smn levels in motoneurons is crucial for proper axon morphology in zebrafish. Sci Rep. 2016;6:27470 pubmed publisher
  7. Materne P, Vazquez E, Sanchez M, Yague Sanz C, Anandhakumar J, Migeot V, et al. Histone H2B ubiquitylation represses gametogenesis by opposing RSC-dependent chromatin remodeling at the ste11 master regulator locus. elife. 2016;5: pubmed publisher
  8. Bertoldo M, Guibert E, Faure M, Guillou F, Ramé C, Nadal Desbarats L, et al. Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality. Mol Cell Endocrinol. 2016;423:96-112 pubmed publisher
  9. Ouyang S, Song Y, Tian Y, Chen Y, Yu X, Wang D. RNF8 deficiency results in neurodegeneration in mice. Neurobiol Aging. 2015;36:2850-2860 pubmed publisher
  10. Hock A, Vigneron A, Vousden K. Ubiquitin-specific peptidase 42 (USP42) functions to deubiquitylate histones and regulate transcriptional activity. J Biol Chem. 2014;289:34862-70 pubmed publisher
  11. DeGennaro C, Alver B, Marguerat S, Stepanova E, Davis C, Bähler J, et al. Spt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast. Mol Cell Biol. 2013;33:4779-92 pubmed publisher
  12. Murphy P, Cipriany B, Wallin C, Ju C, Szeto K, Hagarman J, et al. Single-molecule analysis of combinatorial epigenomic states in normal and tumor cells. Proc Natl Acad Sci U S A. 2013;110:7772-7 pubmed publisher
  13. Gatta R, Mantovani R. NF-Y affects histone acetylation and H2A.Z deposition in cell cycle promoters. Epigenetics. 2011;6:526-34 pubmed
  14. Gatta R, Mantovani R. Single nucleosome ChIPs identify an extensive switch of acetyl marks on cell cycle promoters. Cell Cycle. 2010;9:2149-59 pubmed
  15. Kyriss M, Jin Y, Gallegos I, Sanford J, Wyrick J. Novel functional residues in the core domain of histone H2B regulate yeast gene expression and silencing and affect the response to DNA damage. Mol Cell Biol. 2010;30:3503-18 pubmed publisher