This is a Validated Antibody Database (VAD) review about human HIST1H2AI, based on 18 published articles (read how Labome selects the articles), using HIST1H2AI antibody in all methods. It is aimed to help Labome visitors find the most suited HIST1H2AI antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HIST1H2AI synonym: H2A/c; H2AFC; histone H2A type 1; H2A histone family, member C; H2A.1; histone 1, H2ai; histone H2A/ptl; histone cluster 1, H2ai

Cell Signaling Technology
rabbit monoclonal (D6O3A)
  • western blot; mouse; 1:1000; loading ...; fig 4c
Cell Signaling Technology HIST1H2AI antibody (Cell signaling technology, 12349) was used in western blot on mouse samples at 1:1000 (fig 4c). Nat Commun (2018) ncbi
mouse monoclonal (L88A6)
  • western blot; human; loading ...; fig 1c
In order to study the role of ACK1/TNK2 in histone H4 Tyr88-phosphorylation and androgen receptor expression in prostate cancer, Cell Signaling Technology HIST1H2AI antibody (Cell Signaling, 3636) was used in western blot on human samples (fig 1c). Cancer Cell (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig s4
Cell Signaling Technology HIST1H2AI antibody (cell signalling, 2578) was used in western blot on mouse samples (fig s4). J Cell Sci (2017) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4c
Cell Signaling Technology HIST1H2AI antibody (cell signalling, 2576P) was used in western blot on mouse samples (fig 4c). J Clin Invest (2017) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4c
Cell Signaling Technology HIST1H2AI antibody (cell signalling, 2578P) was used in western blot on mouse samples (fig 4c). J Clin Invest (2017) ncbi
mouse monoclonal (L88A6)
  • western blot; human; loading ...
In order to investigate the role of FACT in sensing DNA torsional stress, Cell Signaling Technology HIST1H2AI antibody (Cell Signaling, 3636S) was used in western blot on human samples . Nucleic Acids Res (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 2
Cell Signaling Technology HIST1H2AI antibody (Cell Signaling, 2578) was used in western blot on mouse samples at 1:1000 (fig 2). Sci Rep (2016) ncbi
rabbit monoclonal (D6O3A)
  • western blot; human; 1:1000
Cell Signaling Technology HIST1H2AI antibody (Cell Signaling, 12349) was used in western blot on human samples at 1:1000. PLoS ONE (2016) ncbi
mouse monoclonal (L88A6)
  • western blot; mouse; fig 4b
Cell Signaling Technology HIST1H2AI antibody (Cell Signaling, 3636s) was used in western blot on mouse samples (fig 4b). Proc Natl Acad Sci U S A (2016) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; rat; fig 5
  • western blot; rat; fig 5
Cell Signaling Technology HIST1H2AI antibody (cell Signaling, 2576) was used in chromatin immunoprecipitation on rat samples (fig 5) and in western blot on rat samples (fig 5). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 4a
In order to elucidate the function of TRIM29 in double stranded break repair, Cell Signaling Technology HIST1H2AI antibody (Cell Signaling, 2,578) was used in western blot on human samples at 1:1000 (fig 4a). Nat Commun (2015) ncbi
rabbit polyclonal
  • flow cytometry; human
In order to elucidate the function of TRIM29 in double stranded break repair, Cell Signaling Technology HIST1H2AI antibody (Cell Signaling, 2,576) was used in flow cytometry on human samples . Nat Commun (2015) ncbi
mouse monoclonal (L88A6)
  • western blot; human; 1:1000
Cell Signaling Technology HIST1H2AI antibody (Cell Signaling, 3636) was used in western blot on human samples at 1:1000. Endocrinology (2015) ncbi
rabbit polyclonal
  • immunoprecipitation; human
In order to study the interaction between BRCA1 tumor suppressor and inositol 1,4,5-trisphosphate receptors and its effect on apoptotic calcium release, Cell Signaling Technology HIST1H2AI antibody (Cell Signaling Technology, 2576) was used in immunoprecipitation on human samples . J Biol Chem (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; human; fig s2
Cell Signaling Technology HIST1H2AI antibody (Cell Signalling, 2578) was used in immunohistochemistry on human samples (fig s2). Aging Cell (2015) ncbi
mouse monoclonal (L88A6)
  • western blot; human; fig 1
Cell Signaling Technology HIST1H2AI antibody (Cell Signaling Technology, L88A6) was used in western blot on human samples (fig 1). Mol Cell Biol (2015) ncbi
mouse monoclonal (L88A6)
  • western blot; human
Cell Signaling Technology HIST1H2AI antibody (Cell Signaling Technology, 3636) was used in western blot on human samples . J Biol Chem (2014) ncbi
EMD Millipore
rabbit polyclonal
  • western blot; human; fig 4
EMD Millipore HIST1H2AI antibody (Merck Millipore, ABE569) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; mouse
EMD Millipore HIST1H2AI antibody (Millipore, ABE327) was used in western blot on mouse samples . Neurobiol Aging (2015) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse; fig 2
In order to show that geriatric satellite cells do not maintain their normal quiescent state in muscle homeostatic conditions and that this irreversibly affects their intrinsic regenerative and self-renewal capacities, EMD Millipore HIST1H2AI antibody (Millipore, ABE569) was used in chromatin immunoprecipitation on mouse samples (fig 2). Nature (2014) ncbi
Articles Reviewed
  1. Panda S, Gekara N. The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex. Nat Commun. 2018;9:4654 pubmed publisher
  2. Mahajan K, Malla P, Lawrence H, Chen Z, Kumar Sinha C, Malik R, et al. ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer. Cancer Cell. 2017;31:790-803.e8 pubmed publisher
  3. Jha K, Tripurani S, Johnson G. TSSK6 is required for γH2AX formation and the histone-to-protamine transition during spermiogenesis. J Cell Sci. 2017;130:1835-1844 pubmed publisher
  4. Wu N, Jia D, Bates B, Basom R, Eberhart C, MacPherson D. A mouse model of MYCN-driven retinoblastoma reveals MYCN-independent tumor reemergence. J Clin Invest. 2017;127:888-898 pubmed publisher
  5. Safina A, Cheney P, Pal M, Brodsky L, Ivanov A, Kirsanov K, et al. FACT is a sensor of DNA torsional stress in eukaryotic cells. Nucleic Acids Res. 2017;45:1925-1945 pubmed publisher
  6. Baleriola J, Álvarez Lindo N, de la Villa P, Bernad A, Blanco L, Suárez T, et al. Increased neuronal death and disturbed axonal growth in the Polμ-deficient mouse embryonic retina. Sci Rep. 2016;6:25928 pubmed publisher
  7. Wu T, Li Y, Liu B, Zhang S, Wu L, Zhu X, et al. Expression of Ferritin Light Chain (FTL) Is Elevated in Glioblastoma, and FTL Silencing Inhibits Glioblastoma Cell Proliferation via the GADD45/JNK Pathway. PLoS ONE. 2016;11:e0149361 pubmed publisher
  8. Ramasamy S, Saez B, Mukhopadhyay S, Ding D, Ahmed A, Chen X, et al. Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway. Proc Natl Acad Sci U S A. 2016;113:1871-6 pubmed publisher
  9. Zhao M, Song Y, Niu H, Tian Y, Yang X, Xie K, et al. Adenovirus-mediated downregulation of the ubiquitin ligase RNF8 sensitizes bladder cancer to radiotherapy. Oncotarget. 2016;7:8956-67 pubmed publisher
  10. Ouyang S, Song Y, Tian Y, Chen Y, Yu X, Wang D. RNF8 deficiency results in neurodegeneration in mice. Neurobiol Aging. 2015;36:2850-2860 pubmed publisher
  11. Namachivayam K, Mohankumar K, Arbach D, Jagadeeswaran R, Jain S, Natarajan V, et al. All-Trans Retinoic Acid Induces TGF-β2 in Intestinal Epithelial Cells via RhoA- and p38α MAPK-Mediated Activation of the Transcription Factor ATF2. PLoS ONE. 2015;10:e0134003 pubmed publisher
  12. Masuda Y, Takahashi H, Sato S, Tomomori Sato C, Saraf A, Washburn M, et al. TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin. Nat Commun. 2015;6:7299 pubmed publisher
  13. Zhong X, Liao Y, Chen L, Liu G, Feng Y, Zeng T, et al. The MicroRNAs in the Pathogenesis of Metabolic Memory. Endocrinology. 2015;156:3157-68 pubmed publisher
  14. Hedgepeth S, Garcia M, Wagner L, Rodriguez A, Chintapalli S, Snyder R, et al. The BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium release. J Biol Chem. 2015;290:7304-13 pubmed publisher
  15. Gibbs Seymour I, Markiewicz E, Bekker Jensen S, Mailand N, Hutchison C. Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage. Aging Cell. 2015;14:162-9 pubmed publisher
  16. Lecona E, Narendra V, Reinberg D. USP7 cooperates with SCML2 to regulate the activity of PRC1. Mol Cell Biol. 2015;35:1157-68 pubmed publisher
  17. Hock A, Vigneron A, Vousden K. Ubiquitin-specific peptidase 42 (USP42) functions to deubiquitylate histones and regulate transcriptional activity. J Biol Chem. 2014;289:34862-70 pubmed publisher
  18. Sousa Victor P, Gutarra S, García Prat L, Rodriguez Ubreva J, Ortet L, Ruiz Bonilla V, et al. Geriatric muscle stem cells switch reversible quiescence into senescence. Nature. 2014;506:316-21 pubmed publisher