This is a Validated Antibody Database (VAD) review about human HEXB, based on 3 published articles (read how Labome selects the articles), using HEXB antibody in all methods. It is aimed to help Labome visitors find the most suited HEXB antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HEXB synonym: ENC-1AS; HEL-248; HEL-S-111; beta-hexosaminidase subunit beta; HCC-7; N-acetyl-beta-glucosaminidase subunit beta; beta-N-acetylhexosaminidase subunit beta; beta-hexosaminidase beta-subunit; cervical cancer proto-oncogene 7 protein; epididymis luminal protein 248; epididymis secretory protein Li 111; hexosaminidase B (beta polypeptide); hexosaminidase subunit B

Santa Cruz Biotechnology
mouse monoclonal (D-9)
  • western blot; human; fig 3a
Santa Cruz Biotechnology HEXB antibody (SantaCruz, sc-376781) was used in western blot on human samples (fig 3a). Hum Mol Genet (2017) ncbi
mouse monoclonal (D-9)
  • western blot; human; 1:500; loading ...; fig 8d
In order to test if glucocerebrosidase activation reduces alpha-synuclein levels, Santa Cruz Biotechnology HEXB antibody (SantaCruz, sc-376781) was used in western blot on human samples at 1:500 (fig 8d). J Neurosci (2016) ncbi
Abcam
rabbit monoclonal (EPR7978)
  • western blot; human
Abcam HEXB antibody (Abcam, ab140649) was used in western blot on human samples . J Hum Genet (2013) ncbi
Articles Reviewed
  1. Kim M, Deng H, Wong Y, Siddique T, Krainc D. The Parkinson's disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking. Hum Mol Genet. 2017;26:729-741 pubmed publisher
  2. Mazzulli J, Zunke F, Tsunemi T, Toker N, Jeon S, Burbulla L, et al. Activation of ?-Glucocerebrosidase Reduces Pathological ?-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons. J Neurosci. 2016;36:7693-706 pubmed publisher
  3. Yasui N, Takaoka Y, Nishio H, Nurputra D, Sekiguchi K, Hamaguchi H, et al. Molecular pathology of Sandhoff disease with p.Arg505Gln in HEXB: application of simulation analysis. J Hum Genet. 2013;58:611-7 pubmed publisher