This is a Validated Antibody Database (VAD) review about human HER2, based on 229 published articles (read how Labome selects the articles), using HER2 antibody in all methods. It is aimed to help Labome visitors find the most suited HER2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HER2 synonym: CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1
Knockout validation
| Cell Signaling Technology domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2165) was used in western blot knockout validation on human samples at 1:200 (fig 1a). Cancers (Basel) (2021) ncbi |
Invitrogen
| mouse monoclonal (e2-4001, 3B5) |
| Invitrogen HER2 antibody (ThermoFisher, MA5-14057) was used in western blot on human samples at 1:1000 (fig 5s2a). elife (2020) ncbi |
| domestic rabbit monoclonal (K.929.9) |
| Invitrogen HER2 antibody (Thermo Fisher, MA5-15050) was used in other on human samples at 1:100 (fig 1b, 1s1a). elife (2020) ncbi |
| mouse monoclonal (2G11) |
| Invitrogen HER2 antibody (Thermo Fisher, BMS120BT) was used in other on human samples at 1:100 (fig 4c). elife (2020) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| Invitrogen HER2 antibody (Thermo Fisher, MA5-14057) was used in immunocytochemistry on human samples at 1:200 (fig 4a) and in western blot on human samples at 1:500 (fig 1). Biomolecules (2020) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| Invitrogen HER2 antibody (Thermo Scientific, MA5-14057) was used in western blot on human samples (fig 1a). Nat Commun (2019) ncbi |
| mouse monoclonal (e2-4001) |
| Invitrogen HER2 antibody (Lab Vision, MS-325-P1) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi |
| domestic rabbit recombinant (SP3) |
| Invitrogen HER2 antibody (Thermo Fisher Scientific, RM-9103-S1) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2a). Cell (2018) ncbi |
| domestic rabbit polyclonal |
| In order to develop a microfluidic immunostaining system for the standardization of immunohistochemical assays, Invitrogen HER2 antibody (Thermo Fisher, PA5-16305) was used in immunohistochemistry - paraffin section on human samples (fig 3d). Sci Rep (2017) ncbi |
| mouse monoclonal (e2-4001) |
| In order to describe a microfluidic western blot for an eight-plex protein panel for individual circulating tumor cells derived from estrogen receptor-positive breast cancer patients, Invitrogen HER2 antibody (Pierce, MA513105) was used in western blot on human samples at 1:10 (fig 2a). Nat Commun (2017) ncbi |
| mouse monoclonal (e2-4001) |
| In order to characterize the molecular identity of uterine carcinosarcomas., Invitrogen HER2 antibody (Lab Vision, MS-325-P1) was used in reverse phase protein lysate microarray on human samples (fig 7a). Cancer Cell (2017) ncbi |
| mouse monoclonal (e2-4001) |
| In order to describe the features of 228 primary cervical cancers, Invitrogen HER2 antibody (Lab Vision, MS-325-P1) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi |
| mouse monoclonal (e2-4001) |
| In order to analyze the context specificity of signaling networks within a causal conceptual framework using reverse-phase protein array time-course assays and network analysis approaches, Invitrogen HER2 antibody (Lab Vision, MS-325-P1) was used in western blot on human samples . Cell Syst (2017) ncbi |
| domestic rabbit monoclonal (K.929.9) |
| In order to determine if PIK3CA mutations contribute to tumor initiation, Invitrogen HER2 antibody (Thermo Scientific, MA5-15050) was used in immunohistochemistry - paraffin section on mouse samples (fig 1b). Oncogenesis (2016) ncbi |
| mouse monoclonal (9G6.10) |
| In order to perform Raman-encoded molecular imaging with five nanoparticle flavors, Invitrogen HER2 antibody (Thermo Scientific, MS-229-PABX) was used in immunohistochemistry on human samples (fig 3a). PLoS ONE (2016) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to optimize in vivo and ex vivo fluorescence imaging for the preclinical development and characterization of therapeutic monoclonal antibodies, Invitrogen HER2 antibody (Thermo Fisher Scientific, SP3) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1c). MAbs (2017) ncbi |
| mouse monoclonal (N12) |
| In order to describe the role of Anks1a in COPII-mediated EphA2 export from the endoplasmic reticulum, Invitrogen HER2 antibody (Neomarkers, MA5-12998) was used in immunocytochemistry on human samples at 1:100 (fig s8), in western blot on human samples at 1:100 (fig s8), in immunocytochemistry on mouse samples at 1:100 (fig s7) and in western blot on mouse samples at 1:100 (fig s7). Nat Commun (2016) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to assess the use of HER2-HER3 dimerization as a biomarker for breast cancer, Invitrogen HER2 antibody (ThermoScientific, e2-4001+3B5) was used in immunocytochemistry on human samples (fig 1b) and in immunohistochemistry on human samples (fig 2a). Oncotarget (2016) ncbi |
| mouse monoclonal (PN2A) |
| In order to identify a role for S100P in the development of trastuzumab-resistance, Invitrogen HER2 antibody (Fisher, MS-1072-P0) was used in western blot on human samples at 1:500 (fig 2d). Oncotarget (2016) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to classify triple-negative breast cancer into subtypes, Invitrogen HER2 antibody (Neomarkers, SP3) was used in immunohistochemistry - paraffin section on human samples at 1:200 (tbl 5). Oncol Lett (2016) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to investigate Bayesian methods for the analysis of exponential decay data, Invitrogen HER2 antibody (Thermo Fisher Scientific, e2-4001+3B5) was used in immunohistochemistry on human samples . PLoS ONE (2016) ncbi |
| mouse monoclonal (e2-4001) |
| In order to develop a new affibody-drug conjugate against HER2-positive cell lines., Invitrogen HER2 antibody (Thermo Scientific Pierce Antibodies, e2-4001) was used in western blot on human samples (fig 5A). J Immunother (2016) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to examine the association between pretreatment molecular and clinical factors and axillary lymph node metastases in early breast cancer, Invitrogen HER2 antibody (Thermo, SP3) was used in immunohistochemistry - paraffin section on human samples at 1:100 (tbl 1). Medicine (Baltimore) (2016) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to identify genetic features regulating cell survival after exposure to radiation., Invitrogen HER2 antibody (Thermo Fisher, MS730P0) was used in western blot on human samples at 1:2000. Nat Commun (2016) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to test if septins contribute to cancer by stabilizing ErbB2, Invitrogen HER2 antibody (Thermo Fisher Scientific, Ab-17) was used in immunoprecipitation on human samples (fig 2b), in immunocytochemistry on human samples at 1:100 (fig 3b) and in western blot on human samples at 1:1000 (fig 1). Biochem J (2016) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to explore the relationship between tumor-infiltrating lymphocytes and the clinical outcomes of triple-negative breast cancers, Invitrogen HER2 antibody (Thermoscientific, SP3) was used in immunohistochemistry on human samples at 1:200. Breast Cancer Res Treat (2016) ncbi |
| mouse monoclonal (2G11) |
| In order to determine how hepatitis C virus activates a neuregulin-driven circuit to modify surface expression of growth factor receptors of the ErbB family, Invitrogen HER2 antibody (eBioscience, BMS120FI) was used in flow cytometry on human samples (fig 5). PLoS ONE (2016) ncbi |
| mouse monoclonal (9G6.10) |
| In order to learn about intraoperative guidance of breast cancer lumpectomy by quantitative molecular phenotyping with topically applied SERS nanoparticles, Invitrogen HER2 antibody (Thermo Scientific, MS-229-PABX) was used in flow cytometry on human samples (fig 5). Sci Rep (2016) ncbi |
| mouse monoclonal (e2-4001) |
| In order to determine the mechanisms of resistance to the pan-HER family inhibitor AZD8931, Invitrogen HER2 antibody (Invitrogen, AHO1011) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 2). Dis Model Mech (2016) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to assess non-small cell lung cancers using a breast cancer-risk predictor gene signature, Invitrogen HER2 antibody (Thermo Scientific, MS-730) was used in immunohistochemistry - paraffin section on human samples at 1:400 (tbl 4). Neoplasia (2015) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to elucidate the role of Runx2 during the early stages of breast cancer and metastasis, Invitrogen HER2 antibody (Thermo Scientific, e2-4001 + 3B5) was used in immunohistochemistry - paraffin section on human samples at 1:200 (tbl 1). Pathol Oncol Res (2016) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to characterize distinct binding preferences for constitutive and stress-induced HSP90 isoforms and conformationally restricted mutants in regards to client proteins and small molecule inhibitors, Invitrogen HER2 antibody (Thermo Scientific, MS-730-P1) was used in western blot on human samples (fig 3). PLoS ONE (2015) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to discuss how to improve treatment of pancreatic ductal adenocarcinomas with trastuzumab emtansine, Invitrogen HER2 antibody (Thermo Fisher Scientific, e2-4001 + 3B5) was used in western blot on human samples at 1:1000 (fig 2). BMC Cancer (2015) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to evaluate the expression of CD24, CD44, CD133 and ALDH1 in invasive ductal carcinoma of the breast, Invitrogen HER2 antibody (Thermo Scientific, RM-9103-R7) was used in immunohistochemistry on human samples at ready to use. Pathol Res Pract (2015) ncbi |
| domestic rabbit monoclonal (EP1045Y) |
| In order to evaluate the expression of CD24, CD44, CD133 and ALDH1 in invasive ductal carcinoma of the breast, Invitrogen HER2 antibody (Thermo Scientific, RM-2111-R7) was used in immunohistochemistry on human samples at ready to use. Pathol Res Pract (2015) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to develop a non-cross-reactive multiplex to measure 8 common breast cancer biomarkers, Invitrogen HER2 antibody (Thermo Fisher, MA5-14509) was used in immunohistochemistry - paraffin section on human samples (fig 1f). Appl Immunohistochem Mol Morphol (2016) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to study breast cancer cell lines and chemomodulatory effects of didox and resveratrol on herceptin cytotoxicity, Invitrogen HER2 antibody (Thermo Scientific, MS-730-PCS) was used in immunocytochemistry on human samples (fig 3). Sci Rep (2015) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to characterize triple-negative breast cancer and the role of epithelial-mesenchymal transition markers, Invitrogen HER2 antibody (Thermo Lab Vision, RM-9103-S) was used in immunohistochemistry - paraffin section on human samples at 1:200 (tbl 2). Breast Cancer Res Treat (2015) ncbi |
| mouse monoclonal (PN2A) |
| In order to study anti-tumor activity of breast cancer models resistant to anti-HER2 drugs due to a dual fatty acid synthase and HER2 signaling blockade, Invitrogen HER2 antibody (Thermo Scientific, MS-1072-P1) was used in western blot on human samples at 1:200 (fig 1). PLoS ONE (2015) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to assess the clinicopathological and immunohistochemical characteristics, and the clinical outcomes, between screen-detected and symptomatic DCIS, Invitrogen HER2 antibody (Thermo Scientific Lab Vision, RM-9103-S) was used in immunohistochemistry - paraffin section on human samples at 1:200. Breast Cancer Res Treat (2015) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to characterize nine mutations in the receptor tyrosine kinase ERBB4 identified in lung adenocarcinoma, Invitrogen HER2 antibody (Thermo Scientific, MA5-14057) was used in immunoprecipitation on human samples at 1 ug/time. Oncogene (2016) ncbi |
| domestic rabbit recombinant (SP3) |
| Invitrogen HER2 antibody (Thermo Scientific, SP3) was used in immunohistochemistry on human samples at 1:100. Breast (2015) ncbi |
| mouse monoclonal (e2-4001) |
| In order to evaluate expression of receptor tyrosine kinases, their ligands, and mutational status and correlate with features observed in solitary fibrous tumors, Invitrogen HER2 antibody (Lab vision, MS-325-PO) was used in immunohistochemistry on human samples at 1:200. Hum Pathol (2015) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to report that gemcitabine treatment increases HER2 expression by low HER2-expressing breast cancer cells, Invitrogen HER2 antibody (Thermo Fisher Scientific, e2-4001 + 3B5) was used in western blot on human samples at 1:1000 (fig 2b). Oncol Rep (2015) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to discuss how to treat the four types of breast cancer, Invitrogen HER2 antibody (Thermo Scientific Lab Vision, SP3) was used in immunohistochemistry - paraffin section on human samples . Niger J Clin Pract (2015) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| Invitrogen HER2 antibody (Thermo Scientific, e2-4001-3B5) was used in immunohistochemistry - paraffin section on human samples at 1:500. Turk J Gastroenterol (2014) ncbi |
| mouse monoclonal (e2-4001) |
| In order to characterize human solid salivary adenoid cystic carcinoma and high frequency of loss of PTEN expression as a targeted therapy, Invitrogen HER2 antibody (Thermo Scientific, MS325B0) was used in immunohistochemistry - paraffin section on human samples (fig 2). Oncotarget (2015) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| Invitrogen HER2 antibody (Lab Vision, e2-4001+ 3B5) was used in immunohistochemistry - paraffin section on human samples at 1:100. World J Urol (2015) ncbi |
| mouse monoclonal (3B5) |
| In order to determine the best method to assess HER2 status in breast cancer samples, Invitrogen HER2 antibody (LabVision, Ab15) was used in immunohistochemistry on human samples . Breast Cancer Res (2015) ncbi |
| mouse monoclonal (e2-4001) |
| In order to determine the best method to assess HER2 status in breast cancer samples, Invitrogen HER2 antibody (LabVision, Ab8) was used in immunohistochemistry on human samples . Breast Cancer Res (2015) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to analyze breast cancer subtypes and retrospective analysis of metastatic behaviour, Invitrogen HER2 antibody (Thermo Scientific, SP3) was used in immunohistochemistry - paraffin section on human samples (tbl 2). Breast Cancer Res Treat (2015) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to determine the rate of human epidermal growth factor receptor-2 discordance and its effect on treatment decisions in patients with advanced gastric cancer, Invitrogen HER2 antibody (Thermo, e2 4001+3B5) was used in immunohistochemistry - paraffin section on human samples . Jpn J Clin Oncol (2015) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to evaluate the presence of cancer stem cells and EMT markers as prognostic markers for breast metaplastic carcinoma, Invitrogen HER2 antibody (Neomarker, RM-9103-R7) was used in immunohistochemistry on human samples at 1:200. Breast Cancer Res Treat (2015) ncbi |
| mouse monoclonal (e2-4001) |
| In order to elucidate the dimerization of ErbB2, Invitrogen HER2 antibody (Neomarkers, Ab8) was used in immunoprecipitation on human samples (fig 3D) and in western blot on human samples (fig 3D). Oncotarget (2015) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to elucidate the dimerization of ErbB2, Invitrogen HER2 antibody (Neomarkers, Ab8) was used in immunoprecipitation on human samples (fig 3D) and in western blot on human samples (fig 3D). Oncotarget (2015) ncbi |
| domestic rabbit recombinant (SP3) |
| Invitrogen HER2 antibody (Lab Vision Corporation, SP3) was used in immunohistochemistry - paraffin section on human samples . Exp Ther Med (2015) ncbi |
| domestic rabbit recombinant (SP3) |
| Invitrogen HER2 antibody (Thermo Scientific, SP3) was used in immunohistochemistry on human samples at 1:100. BMC Womens Health (2014) ncbi |
| mouse monoclonal (9G6.10) |
| Invitrogen HER2 antibody (Thermo Scientific, 9G6.10) was used in western blot on human samples . J Biol Chem (2014) ncbi |
| mouse monoclonal (e2-4001) |
| In order to study mechanism of resistance to the FGFR inhibitor BGJ398 and the FGFR inhibitor ponatinib, Invitrogen HER2 antibody (NeoMarkers, e2-4001) was used in immunoprecipitation on human samples and in western blot on human samples . Oncogene (2015) ncbi |
| mouse monoclonal (e2-4001, 3B5) | In order to study the role of flotillin in the oncogenic effect of ErbB, Invitrogen HER2 antibody (Thermo Fisher Scientific, Ab-17) was used . Biochim Biophys Acta (2014) ncbi | |
| mouse monoclonal (e2-4001) |
| Invitrogen HER2 antibody (LabVision, e2-4001) was used in immunohistochemistry - paraffin section on human samples at 1:300. Head Neck (2015) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to investigate the expression and activity of receptor tyrosine kinases, MAP kinase, AKT, or Hippo pathways in human schwannomas, Invitrogen HER2 antibody (LabVision, Ab-17) was used in immunohistochemistry - paraffin section on human samples . Neuro Oncol (2014) ncbi |
| mouse monoclonal (PN2A) |
| In order to establish a tissue quality index as an intrinsic control for measurement of different effects of preanalytical variables on FFPE tissue, Invitrogen HER2 antibody (Thermo, PN2A) was used in immunohistochemistry - paraffin section on human samples . Lab Invest (2014) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to study non-natural amino acid antibody drug conjugates, Invitrogen HER2 antibody (Thermo, SP3) was used in immunohistochemistry - paraffin section on human samples at 1:200. PLoS ONE (2014) ncbi |
| mouse monoclonal (e2-4001, 3B5) | In order to study the role of neuregulin-1/glial growth factor in Schwann cell migration and its mechanism, Invitrogen HER2 antibody (Thermo Scientific, Ab-17) was used . Genes Cells (2014) ncbi | |
| domestic rabbit monoclonal (EP1045Y) |
| In order to report the clinicopathological features of 9 breast malignant fibrous histiocytoma patients, Invitrogen HER2 antibody (Lab Vision, EP1045Y) was used in immunohistochemistry - paraffin section on human samples at 1:100 (tbl 2). Sci Rep (2013) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to review the contribution of Yes Associated Protein to various types of cancer, Invitrogen HER2 antibody (Neomarkers, SP3) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2). Cell Oncol (Dordr) (2013) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to learn about a new potential marker for low risk of invasion in ductal carcinoma in situ is called basal cytokeratin, Invitrogen HER2 antibody (Thermo Scientific, SP3) was used in immunohistochemistry - paraffin section on human samples at 1:100 (tbl 1). Clinics (Sao Paulo) (2013) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to study targeting sEcad for treatment of breast cancer, Invitrogen HER2 antibody (Thermo Fisher Scientific, Ab-17) was used in immunohistochemistry on mouse samples at 1:1000. Mol Carcinog (2014) ncbi |
| mouse monoclonal (e2-4001) |
| In order to investigate factors that regulate ErbB2-ErbB3 heterodimerization, Invitrogen HER2 antibody (Thermo, Ab-8 (clone e2-4001)) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 1). Carcinogenesis (2013) ncbi |
| mouse monoclonal (e2-4001, 3B5) | In order to study the role of HER2/neu in vasculogenic mimicry in invasive breast carcinoma, Invitrogen HER2 antibody (Thermo SCIENTIFIC, MS-730-P0) was used . J Cell Mol Med (2013) ncbi | |
| mouse monoclonal (e2-4001) |
| In order to study the influence of oncogene expression on cellular lipid profile, Invitrogen HER2 antibody (Biosource, AHO1011) was used in flow cytometry on human samples (fig 5). Biochim Biophys Acta (2012) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to study EGFR gene in triple negative breast cancer and its therapeutic application, Invitrogen HER2 antibody (Neomarker, RM9103-S) was used in immunohistochemistry - paraffin section on human samples at 1:200. Breast Cancer Res (2011) ncbi |
| mouse monoclonal (3B5) |
| In order to demonstrate that the beta4-dependent signaling in human squamous carcinoma cells is dependent on the syndecan family of matrix receptors, Invitrogen HER2 antibody (Fisher, 3B5) was used in immunoprecipitation on human samples (fig 7d) and in western blot on human samples (fig 6a). J Biol Chem (2010) ncbi |
| domestic rabbit recombinant (SP3) |
| In order to study the role of CLDN2 expression in breast cancer development and progression, Invitrogen HER2 antibody (NeoMarkers, SP3) was used in immunohistochemistry - paraffin section on human samples at 1:400 (tbl 3) and in immunohistochemistry on human samples at 1:400. Histopathology (2008) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to examine the role of E-cadherin and ADAM15 in ErbB receptor signaling, Invitrogen HER2 antibody (Lab Vision, e2-4001 + 3B5) was used in immunoprecipitation on human samples and in western blot on human samples . J Biol Chem (2008) ncbi |
| mouse monoclonal (e2-4001, 3B5) |
| In order to investigate ErbB2 internalization, Invitrogen HER2 antibody (Neomarkers, Ab-17) was used in western blot on human samples at 1:3000 (fig 7). J Cell Sci (2006) ncbi |
| mouse monoclonal (9G6.10) |
| In order to suggest that AEE788 is an anticancer agent that deregulates tumor cell proliferation and angiogenic parameters, Invitrogen HER2 antibody (NeoMarkers, MS229-PABX) was used in ELISA on human samples (tbl 2). Cancer Res (2004) ncbi |
Santa Cruz Biotechnology
| mouse monoclonal (3B5) |
| Santa Cruz Biotechnology HER2 antibody (Santa Cruz, 3B5) was used in immunohistochemistry on mouse samples at 1:50 (fig 4b). BMC Dev Biol (2021) ncbi |
| mouse monoclonal |
| Santa Cruz Biotechnology HER2 antibody (Santa Cruz, 3B5) was used in immunohistochemistry on mouse samples at 1:50 (fig 4b). BMC Dev Biol (2021) ncbi |
| mouse monoclonal (3B5) |
| Santa Cruz Biotechnology HER2 antibody (Santa Cruz, sc-33684) was used in western blot on human samples (fig 4g). Theranostics (2021) ncbi |
| mouse monoclonal (3B5) |
| Santa Cruz Biotechnology HER2 antibody (Santa Cruz, sc-33684) was used in flow cytometry on human samples (fig s4b). MBio (2017) ncbi |
| mouse monoclonal (3B5) |
| Santa Cruz Biotechnology HER2 antibody (Santa Cruz Biotechnology, 3B5) was used in ChIP-Seq on mouse samples (fig s3a), in chromatin immunoprecipitation on mouse samples (fig s3b), in ChIP-Seq on human samples (fig s3c) and in chromatin immunoprecipitation on human samples (fig s3e). PLoS Genet (2017) ncbi |
| mouse monoclonal |
| Santa Cruz Biotechnology HER2 antibody (Santa Cruz Biotechnology, 3B5) was used in ChIP-Seq on mouse samples (fig s3a), in chromatin immunoprecipitation on mouse samples (fig s3b), in ChIP-Seq on human samples (fig s3c) and in chromatin immunoprecipitation on human samples (fig s3e). PLoS Genet (2017) ncbi |
| mouse monoclonal (9G6) |
| Santa Cruz Biotechnology HER2 antibody (Santa Cruz, sc-08) was used in western blot on human samples at 1:500 (fig 5d). Sci Rep (2017) ncbi |
| mouse monoclonal (3B5) |
| In order to assess the role of Nrg1 signaling to Alzheimer's disease pathogenesis, Santa Cruz Biotechnology HER2 antibody (Santa Cruz, sc-33684) was used in western blot on human samples at 1:1000 (fig 2). Mol Med Rep (2016) ncbi |
| mouse monoclonal (19G5) |
| In order to determine the effect of a mixture of two monoclonal antibodies against non-overlapping epitopes of HER2 on HER2 stability and localization, Santa Cruz Biotechnology HER2 antibody (Santa Cruz, 19G5) was used in western blot on human samples (fig 5c). J Cell Mol Med (2016) ncbi |
| mouse monoclonal (3B5) |
| In order to study the alterations of brain Neuregulin-1 signaling during neuroinflammation, Santa Cruz Biotechnology HER2 antibody (Santa Cruz, sc-33684) was used in western blot on mouse samples at 1:500 (fig 2). Mol Med Rep (2016) ncbi |
| mouse monoclonal (7F8) |
| In order to study the alterations of brain Neuregulin-1 signaling during neuroinflammation, Santa Cruz Biotechnology HER2 antibody (Santa Cruz, sc-81508) was used in western blot on mouse samples at 1:500 (fig 2). Mol Med Rep (2016) ncbi |
| mouse monoclonal (F-11) |
| Santa Cruz Biotechnology HER2 antibody (Santa Cruz, sc-7301) was used in immunoprecipitation on human samples (fig 1). Oncogenesis (2016) ncbi |
| mouse monoclonal (24D2) |
| Santa Cruz Biotechnology HER2 antibody (Santa Cruz Biotechnology, SC-23864) was used in flow cytometry on mouse samples (fig 5). Analyst (2015) ncbi |
| mouse monoclonal (3B5) |
| Santa Cruz Biotechnology HER2 antibody (SantaCruz, sc-33684) was used in immunohistochemistry - paraffin section on human samples (tbl 3). Genes Cancer (2015) ncbi |
| mouse monoclonal (F-11) |
| In order to elucidate the dimerization of ErbB2, Santa Cruz Biotechnology HER2 antibody (Santa Cruz, sc-7301) was used in western blot on human samples (fig 3A). Oncotarget (2015) ncbi |
| mouse monoclonal (3B5) |
| Santa Cruz Biotechnology HER2 antibody (Santa Cruz Biotechnology, sc-33684) was used in western blot on human samples . Int J Oncol (2014) ncbi |
| mouse monoclonal (9G6) |
| Santa Cruz Biotechnology HER2 antibody (Santa Cruz, sc-08) was used in immunohistochemistry - paraffin section on human samples at 1:100. J Biol Chem (2014) ncbi |
Abcam
| domestic rabbit monoclonal (EPR19547-12) |
| Abcam HER2 antibody (Abcam, ab214275) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig s1c). Sci Adv (2022) ncbi |
| domestic rabbit monoclonal (EP2324Y) |
| Abcam HER2 antibody (Abcam, ab237060) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 9i). J Clin Invest (2022) ncbi |
| domestic rabbit monoclonal (EPR19547-12) |
| Abcam HER2 antibody (Abcam, ab214275) was used in immunohistochemistry on human samples at 1:1000 (fig s4). NPJ Breast Cancer (2021) ncbi |
| domestic rabbit monoclonal (EP1045Y) |
| Abcam HER2 antibody (Abcam, ab134182) was used in western blot on human samples at 1:1000 (fig 7c). Theranostics (2020) ncbi |
| domestic rabbit monoclonal |
| Abcam HER2 antibody (Abcam, ab53290) was used in other on human samples at 1:100 (fig 2d). elife (2020) ncbi |
| domestic rabbit polyclonal |
| Abcam HER2 antibody (Abcam, ab47262) was used in western blot on rat samples at 1:500 (fig 5a). Biomed Res Int (2019) ncbi |
| mouse monoclonal (3B5) |
| Abcam HER2 antibody (Abcam, AB16901) was used in immunohistochemistry on mouse samples (fig 2g). Nature (2017) ncbi |
| domestic rabbit monoclonal (EP1045Y) |
| In order to develop a microfluidic immunostaining system for the standardization of immunohistochemical assays, Abcam HER2 antibody (Abcam, ab134182) was used in immunohistochemistry - paraffin section on human samples (fig 3d). Sci Rep (2017) ncbi |
| mouse monoclonal (9G6) | Abcam HER2 antibody (abcam, ab16899) was used . PLoS ONE (2017) ncbi | |
| domestic rabbit monoclonal (EP2324Y) |
| Abcam HER2 antibody (Abcam, ab108371) was used in immunohistochemistry on mouse samples at 1:100 (fig 5a). J Clin Invest (2016) ncbi |
| domestic rabbit monoclonal (SP3) |
| In order to investigate the interaction between breast cancer subtype and treatment using data from a breast cancer trial randomizing women to adjuvant chemotherapy, Abcam HER2 antibody (Abcam, SP3) was used in immunohistochemistry - paraffin section on human samples (fig 2b). Clin Cancer Res (2017) ncbi |
| domestic rabbit polyclonal |
| Abcam HER2 antibody (Abcam, ab47262) was used in immunohistochemistry - paraffin section on mouse samples (fig 6). Oncotarget (2016) ncbi |
| Abcam HER2 antibody (Abcam, ab131104) was used in western blot on human samples (fig 1). Breast Cancer Res (2015) ncbi |
BioLegend
| mouse monoclonal (24D2) |
| BioLegend HER2 antibody (BioLegend, 324404) was used in flow cytometry on human samples . Front Immunol (2022) ncbi |
| mouse monoclonal (24D2) |
| BioLegend HER2 antibody (BioLegend, 324408) was used in flow cytometry on human samples at 1:100 (fig s6d). J Immunother Cancer (2022) ncbi |
| mouse monoclonal (24D2) |
| BioLegend HER2 antibody (BioLegend, 324412) was used in flow cytometry on human samples (fig 2). Life (Basel) (2021) ncbi |
| mouse monoclonal (24D2) |
| BioLegend HER2 antibody (BioLegend, cat324412) was used in western blot on human samples at 1:100 (fig ex7d). Nat Med (2019) ncbi |
| mouse monoclonal (24D2) |
| BioLegend HER2 antibody (Biolegend, 324412) was used in flow cytometry on mouse samples at 1:100 (fig 1m). Nat Cell Biol (2019) ncbi |
| mouse monoclonal (24D2) |
| BioLegend HER2 antibody (BioLegend, 324402) was used in other on human samples at 500 ug/ml (fig 1). J Extracell Vesicles (2016) ncbi |
| mouse monoclonal (24D2) | BioLegend HER2 antibody (Biolegend, 324405) was used . Sci Rep (2015) ncbi | |
| mouse monoclonal (24D2) |
| In order to discuss how to improve treatment of pancreatic ductal adenocarcinomas with trastuzumab emtansine, BioLegend HER2 antibody (BioLegend, 24D2) was used in flow cytometry on human samples (fig 2). BMC Cancer (2015) ncbi |
| mouse monoclonal (24D2) |
| In order to report that gemcitabine treatment increases HER2 expression by low HER2-expressing breast cancer cells, BioLegend HER2 antibody (BioLegend, 24D2) was used in flow cytometry on human samples (fig 4). Oncol Rep (2015) ncbi |
R&D Systems
| mouse monoclonal (191924) |
| R&D Systems HER2 antibody (R&D Catalog, FAB1129A) was used in flow cytometry on human samples (fig s2c, s2d). Nat Commun (2022) ncbi |
| domestic goat polyclonal |
| R&D Systems HER2 antibody (Biotechne, BAF1129) was used in flow cytometry on human samples at 1:200 (fig s4a). Cancer Res (2021) ncbi |
OriGene
| mouse monoclonal (UMAB36) |
| OriGene HER2 antibody (OriGene Technologies, UMAB36) was used in western blot on human samples at 1:2000 (fig 1c). Biochem Biophys Res Commun (2017) ncbi |
| mouse monoclonal (OTI4F10) |
| In order to investigate the role of channel gating in mammalian proteasomes, OriGene HER2 antibody (OriGene, TA503443) was used in western blot on human samples at 1:1000 (fig s8). Nat Commun (2016) ncbi |
Novus Biologicals
| domestic rabbit polyclonal (MT1/410) |
| Novus Biologicals HER2 antibody (Novus Biologicals, NBP1-84584) was used in immunohistochemistry on mouse samples (fig 6a). Cell Mol Gastroenterol Hepatol (2019) ncbi |
Cell Signaling Technology
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (CST, 8609) was used in western blot on human samples at 1:1000 (fig 1f) and in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig s5a). Allergy Asthma Immunol Res (2022) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 4290S) was used in western blot on human samples at 1:1000 (fig 4a). Nature (2022) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (CST, 4290) was used in western blot on human samples (fig 6a, 6b, 6c, 6d). Cell Oncol (Dordr) (2022) ncbi |
| domestic rabbit monoclonal (D66B7) |
| Cell Signaling Technology HER2 antibody (CST, 6942) was used in western blot on human samples (fig 6a, 6b, 6c, 6d). Cell Oncol (Dordr) (2022) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 4290) was used in immunohistochemistry - paraffin section on mouse samples (fig 2a). Cancers (Basel) (2022) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in immunohistochemistry on mouse samples at 1:500. Nat Commun (2022) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 4290S) was used in western blot on human samples (fig 3a). Thorac Cancer (2022) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2243T) was used in western blot on human samples (fig 3a). Thorac Cancer (2022) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (CST, 2242) was used in western blot on human samples (fig 4). Cancers (Basel) (2022) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (CST, 2165) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 4b). Nat Cancer (2022) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in immunoprecipitation on mouse samples at 1:100 (fig 11) and in western blot on mouse samples at 1:1000 (fig 9e). J Clin Invest (2022) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on mouse samples at 1:1000 (fig 9e). J Clin Invest (2022) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell signaling, 29D8) was used in western blot on human samples at 1:1000 (fig 3b, s4c) and in western blot on mouse samples at 1:1000 (fig 3a). Proc Natl Acad Sci U S A (2021) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (CST, 4290) was used in western blot on human samples at 1:1000 (fig s1a). NPJ Breast Cancer (2021) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (CST, 3250s) was used in western blot on mouse samples (fig 4b). J Cell Mol Med (2021) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2242S) was used in immunohistochemistry on human samples at 1:50. BMC Cancer (2021) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 4290) was used in western blot on human samples (fig 6a). J Exp Clin Cancer Res (2021) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 4290) was used in western blot on human samples (fig 1c). Am J Cancer Res (2021) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 4290) was used in western blot on mouse samples at 1:1000 (fig 3c, 3e, 3f). Arterioscler Thromb Vasc Biol (2021) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in immunohistochemistry on mouse samples at 1:500 (fig 1g). Oncogene (2021) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2165) was used in immunocytochemistry on human samples (fig 2b) and in western blot on human samples (fig 2c). Theranostics (2021) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2165) was used in western blot knockout validation on human samples at 1:200 (fig 1a). Cancers (Basel) (2021) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on mouse samples . Cell Rep (2021) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in immunohistochemistry on mouse samples (fig s2a) and in western blot on mouse samples (fig s2b). Cell Rep (2021) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 1c). Nat Commun (2021) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig s2f). Mol Oncol (2021) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2241) was used in western blot on mouse samples at 1:1000 (fig 4a). Cancer Sci (2021) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on mouse samples at 1:1000 (fig 4a). Cancer Sci (2021) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 29D8) was used in western blot on mouse samples at 1:1000 (fig 8b). J Clin Invest (2021) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig 3a). Cancer Res (2021) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2243S) was used in other on human samples at 1:100 (fig 2d). elife (2020) ncbi |
| domestic rabbit monoclonal (D66B7) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 6942S) was used in other on human samples at 1:100 (fig 2d). elife (2020) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 4290) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2). BMC Cancer (2020) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (CST, 29D8) was used in western blot on human samples (fig 1b, 2b). EBioMedicine (2020) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2242) was used in western blot on mouse samples at 1:1000 (fig s1d). Nat Commun (2019) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (CST, 2165) was used in western blot on human samples (fig 1a). Cell Commun Signal (2019) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Signalling Technology, 2241) was used in western blot on mouse samples at 1:1000 (fig 3d). Breast Cancer Res (2019) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (CST, 2243S) was used in western blot on human samples at 1:1000 (fig 3c, 3d, s8b). Science (2019) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on human samples (fig 5f). Breast Cancer Res (2019) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signalling, D8F12) was used in western blot on mouse samples (fig 4c). Nutrients (2019) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 4290) was used in western blot on human samples (fig s2). Breast Cancer Res (2019) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on human samples (fig s3b). Oncogene (2019) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig s3b). Oncogene (2019) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 4290) was used in western blot on human samples (fig 5e). Cell Res (2018) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on human samples (fig 5e). Cell Res (2018) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (CST, 4290) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 6c). Nat Commun (2018) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 4290) was used in western blot on human samples at 1:1000 (fig 1e). Science (2018) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on human samples (fig 2b). Oncotarget (2017) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2247) was used in western blot on human samples (fig 2b). Oncotarget (2017) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2242) was used in western blot on human samples (fig 1c). Oncotarget (2017) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (cell signaling, 2249) was used in western blot on mouse samples at 1:1000 (fig 3c). Oncogene (2017) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to observe a novel role for ErbB4 in macrophage apoptosis, Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on mouse samples at 1:1000 (fig 1g). Cell Death Dis (2017) ncbi |
| domestic rabbit monoclonal (D8F12) |
| In order to report that lactate dehydrogenase A phosphorylation results in pro-invasive, anti-anoikis, and pro-metastatic advantages to cancer cells, Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 4290) was used in immunohistochemistry on human samples at 1:500 (fig 7b) and in western blot on human samples (fig 3c). Oncogene (2017) ncbi |
| domestic rabbit polyclonal |
| In order to report that lactate dehydrogenase A phosphorylation results in pro-invasive, anti-anoikis, and pro-metastatic advantages to cancer cells, Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2247) was used in western blot on human samples (fig 3c). Oncogene (2017) ncbi |
| domestic rabbit monoclonal (D66B7) |
| In order to discover regions of rare genetic variation that contribute to emphysema with severe airflow obstruction, Cell Signaling Technology HER2 antibody (Cell Signaling, 6942) was used in western blot on human samples (fig 5a). Am J Respir Crit Care Med (2017) ncbi |
| domestic rabbit monoclonal (D8F12) |
| In order to discover regions of rare genetic variation that contribute to emphysema with severe airflow obstruction, Cell Signaling Technology HER2 antibody (Cell Signaling, 4290) was used in western blot on human samples (fig 5a). Am J Respir Crit Care Med (2017) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2241) was used in western blot on human samples (fig s6). Sci Rep (2016) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 4290) was used in immunocytochemistry on human samples at 1:100 (fig 2b) and in western blot on human samples (fig 2a). Sci Rep (2016) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on human samples (fig s6). Sci Rep (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to assess the contribution of amphiregulin, epidermal growth factor, heparin-binding epidermal growth factor, and transforming growth factor alpha in the responsiveness of gastric cancer cell lines to cetuximab and trastuzumab, Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on human samples at 1:1000 (fig 3). J Cancer Res Clin Oncol (2017) ncbi |
| domestic rabbit polyclonal |
| In order to assess the contribution of amphiregulin, epidermal growth factor, heparin-binding epidermal growth factor, and transforming growth factor alpha in the responsiveness of gastric cancer cell lines to cetuximab and trastuzumab, Cell Signaling Technology HER2 antibody (Cell Signaling, 2247) was used in western blot on human samples at 1:1000 (fig 3). J Cancer Res Clin Oncol (2017) ncbi |
| domestic rabbit polyclonal |
| In order to show that 2-hydroxyoleic acid treatment alters cell signaling and intracellular transport, Cell Signaling Technology HER2 antibody (Cell Signaling, 2241) was used in western blot on human samples (fig 3a). Oncotarget (2016) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2242) was used in western blot on human samples at 1:2000 (fig s6a). Nat Cell Biol (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to demonstrate the bipartite role of Hsp90 in chaperoning CRAF kinase, Cell Signaling Technology HER2 antibody (Cell Signaling, 2165S) was used in western blot on human samples at 1:1000 (fig 4g). J Biol Chem (2016) ncbi |
| domestic rabbit monoclonal (6B12) |
| In order to demonstrate the bipartite role of Hsp90 in chaperoning CRAF kinase, Cell Signaling Technology HER2 antibody (Cell Signaling, 2243S) was used in western blot on human samples at 1:1000 (fig 4g). J Biol Chem (2016) ncbi |
| domestic rabbit polyclonal |
| In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology HER2 antibody (Cell Signaling, 2241) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 29D8) was used in flow cytometry on human samples (fig 1a), in immunocytochemistry on human samples and in immunohistochemistry on human samples . Nature (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to study how CUB domain-containing protein1 contributes to metastasis and drug resistance, Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig 2a). Breast Cancer Res (2016) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell signaling, D8F12) was used in immunohistochemistry - paraffin section on human samples (tbl 1). Oncotarget (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to determine the effect of a mixture of two monoclonal antibodies against non-overlapping epitopes of HER2 on HER2 stability and localization, Cell Signaling Technology HER2 antibody (Cell signaling, 29D8) was used in immunoprecipitation on human samples (fig s8). J Cell Mol Med (2016) ncbi |
| domestic rabbit polyclonal |
| In order to identify a role for S100P in the development of trastuzumab-resistance, Cell Signaling Technology HER2 antibody (Cell Signaling, 2242S) was used in western blot on human samples at 1:1000 (fig 2c). Oncotarget (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to assess the importance of the IGF1R tyrosine kinase in triple-negative gastric cancer with and without oncogenic KRAS, BRAF or PI3K3CA mutations, Cell Signaling Technology HER2 antibody (Cell signaling, 2165) was used in western blot on human samples (fig 1a). Oncotarget (2016) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2249) was used in western blot on human samples at 1:500 (fig s2). Nat Commun (2016) ncbi |
| domestic rabbit polyclonal |
| In order to investigate the interaction between MUC13 and HER2, Cell Signaling Technology HER2 antibody (Cell Signaling, 2247) was used in western blot on human samples (fig 3a). Oncogene (2017) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (cell signalling, 2243) was used in western blot on human samples (fig 4b). Oncotarget (2016) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (cell signalling, 2242) was used in western blot on human samples (fig 4a). Oncotarget (2016) ncbi |
| domestic rabbit polyclonal |
| In order to identify genetic features regulating cell survival after exposure to radiation., Cell Signaling Technology HER2 antibody (Cell Signalling, 2247) was used in western blot on human samples at 1:1000 (fig 5f). Nat Commun (2016) ncbi |
| domestic rabbit monoclonal (29D8) | Cell Signaling Technology HER2 antibody (CST, 2165S) was used . Oncogenesis (2016) ncbi | |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell signaling, 2165) was used in western blot on human samples at 1:500 (fig 2). elife (2016) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 4290) was used in immunohistochemistry - paraffin section on mouse samples (fig 6). Oncotarget (2016) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on human samples (fig 1). Oncogenesis (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to determine how hepatitis C virus activates a neuregulin-driven circuit to modify surface expression of growth factor receptors of the ErbB family, Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig 1b). PLoS ONE (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2165) was used in western blot on human samples (fig 1). Oncogene (2016) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2249) was used in western blot on human samples (fig 3b). Oncogene (2016) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2242) was used in immunocytochemistry on human samples (fig s2) and in western blot on human samples (fig s3a). Oncogene (2016) ncbi |
| domestic rabbit polyclonal |
| In order to characterize colorectal cancer and nuclear localization of YBX1 and uncoupling of EGFR-RAS signaling, Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2242) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 2). Oncogenesis (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signalling, 2165S) was used in immunocytochemistry on human samples (fig 2) and in western blot on human samples (fig 2). Oxid Med Cell Longev (2016) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Signalling, 2241S) was used in immunocytochemistry on mouse samples and in western blot on human samples (fig 4). Oxid Med Cell Longev (2016) ncbi |
| domestic rabbit monoclonal (6B12) |
| In order to study the interactions between PMCA2 and HER2 in breast cancer cells, Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2243) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 1). Proc Natl Acad Sci U S A (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to demonstrate that receptor tyrosine kinase-like orphan receptor 1 is a scaffold for cavin-1 and caveolin-1, Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on human samples at 1:200 (fig 2b). Nat Commun (2016) ncbi |
| mouse monoclonal (44E7) |
| In order to determine the mechanisms of resistance to the pan-HER family inhibitor AZD8931, Cell Signaling Technology HER2 antibody (Cell Signaling, 2248) was used in western blot on human samples at 1:1000. Dis Model Mech (2016) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell signaling, 2243) was used in western blot on human samples (fig 3a). Oncotarget (2016) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 4290S) was used in western blot on dogs samples at 1:1000 (fig 5). PLoS ONE (2015) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to test if ado-trastuzumab emtansine overcomes trastuzumab resistance in murine models of brain metastases, Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on human samples at 1:1000 (fig 7e). J Natl Cancer Inst (2016) ncbi |
| domestic rabbit monoclonal (6B12) |
| In order to test if ado-trastuzumab emtansine overcomes trastuzumab resistance in murine models of brain metastases, Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on human samples at 1:1000 (fig 7e). J Natl Cancer Inst (2016) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology HER2 antibody (Cell Sgnaling, 2247) was used in western blot on human samples at 1:1000 (fig 5C; S6B). Mol Oncol (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Sgnaling, 29D8) was used in western blot on human samples at 1:1000 (fig 5C; S6B). Mol Oncol (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in immunocytochemistry on human samples (fig 4). PLoS ONE (2015) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell signaling, 4290) was used in western blot on human samples (fig 4a). J Biol Chem (2015) ncbi |
| domestic rabbit monoclonal (D66B7) |
| Cell Signaling Technology HER2 antibody (Cell signaling, 6942) was used in western blot on human samples (fig 2a). J Biol Chem (2015) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to develop a non-cross-reactive multiplex to measure 8 common breast cancer biomarkers, Cell Signaling Technology HER2 antibody (Cell Signaling, 29D8) was used in immunohistochemistry - paraffin section on human samples (fig 1f). Appl Immunohistochem Mol Morphol (2016) ncbi |
| mouse monoclonal (44E7) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2248) was used in western blot on human samples (fig 5b) and in western blot on mouse samples (fig 5b). Mol Ther (2015) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2243) was used in western blot on mouse samples (fig 5b). Mol Ther (2015) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig 4). EBioMedicine (2015) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on human samples (fig 4). EBioMedicine (2015) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on human samples (fig 2). Oncotarget (2015) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to develop and characterize patient-derived primary xenografts to a model of muscle invasive bladder cancer, Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in immunohistochemistry - paraffin section on human samples at 1:25. Oncotarget (2015) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to study the role of Tn expression and post-translationally modifications in pancreatic ductal adenocarcinoma, Cell Signaling Technology HER2 antibody (Cell Signaling, #2165) was used in western blot on human samples at 1:100. Mol Cancer (2015) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on mouse samples at 1:1000 (fig 5b). PLoS ONE (2015) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2165) was used in western blot on human samples (fig 4f, 4g, 4h). Oncotarget (2015) ncbi |
| domestic rabbit monoclonal (29D8) | In order to characterize capabilities and potentials of extracellular vesicle (EV) array, Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2165) was used . J Extracell Vesicles (2015) ncbi | |
| domestic rabbit monoclonal (6B12) |
| In order to elucidate the dimerization of ErbB2, Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on human samples (fig 3A). Oncotarget (2015) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2165) was used in western blot on human samples . J Diabetes (2016) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 1). Breast Cancer Res (2015) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig s1). Oncogene (2015) ncbi |
| mouse monoclonal (44E7) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2248) was used in western blot on human samples at 1:1000 (fig 2). elife (2014) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to identify mechanisms by which metastatic gastroesophageal adenocarcinomas develop resistance to ERBB2 inhibition, Cell Signaling Technology HER2 antibody (Cell Signaling Technologies, 2165) was used in western blot on human samples . PLoS ONE (2014) ncbi |
| domestic rabbit monoclonal (6B12) |
| In order to identify mechanisms by which metastatic gastroesophageal adenocarcinomas develop resistance to ERBB2 inhibition, Cell Signaling Technology HER2 antibody (Cell Signaling Technologies, 2243) was used in western blot on human samples . PLoS ONE (2014) ncbi |
| domestic rabbit monoclonal (D8F12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 4290) was used in western blot on human samples . Cancer Res (2014) ncbi |
| domestic rabbit monoclonal (6B12) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 2243) was used in western blot on human samples . Cancer Res (2014) ncbi |
| domestic rabbit monoclonal (D66B7) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 6942) was used in western blot on human samples . Cancer Res (2014) ncbi |
| domestic rabbit monoclonal (6B12) |
| In order to study mechanism of resistance to the FGFR inhibitor BGJ398 and the FGFR inhibitor ponatinib, Cell Signaling Technology HER2 antibody (cell signaling, 2243S) was used in western blot on human samples . Oncogene (2015) ncbi |
| mouse monoclonal (44E7) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 2248) was used in western blot on human samples at 1:1000. Front Endocrinol (Lausanne) (2014) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to study the role of flotillin in the oncogenic effect of ErbB, Cell Signaling Technology HER2 antibody (Cell Signaling, 29D8) was used in immunocytochemistry on human samples and in western blot on human samples . Biochim Biophys Acta (2014) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell signaling, 2165) was used in western blot on human samples (fig 1a). Int J Oncol (2014) ncbi |
| domestic rabbit monoclonal (29D8) |
| In order to study targeting sEcad for treatment of breast cancer, Cell Signaling Technology HER2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig 2). Mol Carcinog (2014) ncbi |
| domestic rabbit monoclonal (6B12) |
| In order to study targeting sEcad for treatment of breast cancer, Cell Signaling Technology HER2 antibody (Cell Signaling, 2243) was used in western blot on human samples (fig 2). Mol Carcinog (2014) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling, 29D8) was used in immunocytochemistry on mouse samples at 1:200 and in western blot on mouse samples at 1:1000. Dev Biol (2013) ncbi |
| domestic rabbit monoclonal (29D8) |
| Cell Signaling Technology HER2 antibody (Cell Signaling Technology, 29D8) was used in immunocytochemistry on human samples at 1:150. Breast Cancer Res (2011) ncbi |
Dako
| domestic rabbit polyclonal |
| Dako HER2 antibody (Dako, A0485) was used in immunohistochemistry - paraffin section on mouse samples (fig 5a). Front Cell Dev Biol (2022) ncbi |
| domestic rabbit polyclonal |
| Dako HER2 antibody (Dako, A0485) was used in immunohistochemistry - paraffin section on mouse samples at 1:250 (fig s2a). Cancer Res (2021) ncbi |
| domestic rabbit polyclonal |
| In order to develop a microfluidic immunostaining system for the standardization of immunohistochemical assays, Dako HER2 antibody (Dako, A0485) was used in immunohistochemistry - paraffin section on human samples at 1.6 ug/ml (fig 3d). Sci Rep (2017) ncbi |
| domestic rabbit polyclonal |
| In order to compare HER2 and prolactin receptor trafficking, Dako HER2 antibody (DAKO, A0485) was used in western blot on human samples (fig 3a). Mol Cancer Ther (2017) ncbi |
| domestic rabbit polyclonal |
| In order to study the architecture of the mouse mammary gland using high-resolution 3D imaging, Dako HER2 antibody (DAKO, A0485) was used in immunohistochemistry - paraffin section on mouse samples (fig 6c). Breast Cancer Res (2016) ncbi |
| domestic rabbit polyclonal |
| In order to suggest that EGFR promotes survival of prostate tumor-initiating cells and circulating tumor cells that metastasize to bone, whereas HER2 supports the growth of prostate cancer cells once they are established at metastatic sites, Dako HER2 antibody (Dako, A0485) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1a). Cancer Res (2017) ncbi |
| domestic rabbit polyclonal |
| In order to investigate the contribution of PI3K/AKT pathway to the development of radiation carcinogenesis, Dako HER2 antibody (DAKO, A0485) was used in immunohistochemistry - paraffin section on rat samples (fig 1). J Radiat Res (2017) ncbi |
| domestic rabbit polyclonal |
| In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Dako HER2 antibody (Dako, A0485) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi |
| domestic rabbit polyclonal |
| In order to describe the effects of HER2 overexpression in breast cancer cells, Dako HER2 antibody (Dako, A0485) was used in western blot on human samples (fig s1). Nat Commun (2016) ncbi |
| domestic rabbit polyclonal |
| Dako HER2 antibody (Dako, A0485) was used in immunohistochemistry - paraffin section on human samples at 1:250 (tbl 1). BMC Cancer (2016) ncbi |
| domestic rabbit polyclonal |
| In order to investigate the interaction between MUC13 and HER2, Dako HER2 antibody (Dako, A0485) was used in immunoprecipitation on human samples (fig 1b), in immunocytochemistry on human samples (fig 1a) and in western blot on human samples (fig 1b). Oncogene (2017) ncbi |
| domestic rabbit polyclonal |
| In order to analyze the production of a synergistic effect on cancer cell proliferation and migration in vitro due to dual targeting of ERBB2 and EGFR pathways, Dako HER2 antibody (Dako, A0485) was used in western blot on dogs samples at 1:1000 (fig 1a). Vet Comp Oncol (2017) ncbi |
| domestic rabbit polyclonal |
| Dako HER2 antibody (Dako, A0485) was used in immunohistochemistry on human samples (fig 1). Mol Imaging Biol (2016) ncbi |
| domestic rabbit polyclonal |
| In order to utilize ovarian cancer xenograft models to study dynamic modulation of phosphoprotein expression, Dako HER2 antibody (Dako, A0485) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig s1). BMC Cancer (2016) ncbi |
| domestic rabbit polyclonal |
| In order to develop an assay to measure serum HER2 in order to diagnose cats with mammary carcinomas, Dako HER2 antibody (Dako, A0485) was used in western blot on cat samples at 1:3,500 (fig 5b). Oncotarget (2016) ncbi |
| domestic rabbit polyclonal |
| In order to use microfluidic immunofluorescence staining to quantify HER2 gene copies, Dako HER2 antibody (Dako, A0485) was used in immunohistochemistry - paraffin section on human samples (tbl s2). Sci Rep (2016) ncbi |
| domestic rabbit polyclonal |
| In order to characterize aggressive tumors in African breast cancer and the strong expression of hypoxia-inducible factor-1 alpha (HIF-1alpha) and its association with Axl expression, Dako HER2 antibody (Dako, A0485) was used in immunohistochemistry - paraffin section on human samples at 1:500. PLoS ONE (2016) ncbi |
Ventana
| domestic rabbit monoclonal (4B5) |
| Ventana HER2 antibody (Ventana, 4B5) was used in immunohistochemistry - paraffin section on mouse samples . Cell Mol Gastroenterol Hepatol (2021) ncbi |
| domestic rabbit monoclonal (4B5) |
| Ventana HER2 antibody (Ventana, 4B5) was used in immunohistochemistry - paraffin section on human samples (fig 3d). Sci Rep (2021) ncbi |
| domestic rabbit monoclonal (4B5) |
| Ventana HER2 antibody (Ventana, 4B5) was used in immunohistochemistry on human samples at 1:250. Mod Pathol (2020) ncbi |
| domestic rabbit monoclonal (4B5) |
| Ventana HER2 antibody (Ventana, 4B5) was used in immunohistochemistry - paraffin section on human samples (fig 1d). Sci Rep (2020) ncbi |
| domestic rabbit monoclonal (4B5) |
| Ventana HER2 antibody (Ventana, 4B5) was used in immunocytochemistry on human samples (fig 1c). Nat Commun (2019) ncbi |
| domestic rabbit monoclonal (4B5) |
| Ventana HER2 antibody (Ventana, 4B5) was used in immunohistochemistry - paraffin section on human samples (tbl s1). Am J Pathol (2017) ncbi |
| domestic rabbit monoclonal (4B5) |
| Ventana HER2 antibody (Ventana, 4B5) was used in immunohistochemistry - paraffin section on human samples (fig 1g) and in western blot on human samples at 1:10 (fig 1c). Biochem Biophys Res Commun (2017) ncbi |
| domestic rabbit monoclonal (4B5) |
| In order to characterize the spindle cell type of metaplastic breast carcinoma with myoepithelial features and report that this subtype exhibits a higher frequency of PIK3CA mutation than other types of metaplastic breast carcinoma, Ventana HER2 antibody (Ventana, 4B5) was used in immunohistochemistry - paraffin section on human samples (tbl 3). Virchows Arch (2016) ncbi |
| domestic rabbit monoclonal (4B5) |
| In order to report the clinicopathological features and prognostic factors of pregnancy-associated gastric cancer, Ventana HER2 antibody (Ventana, 4B5) was used in immunohistochemistry on human samples . Gut Liver (2016) ncbi |
| domestic rabbit monoclonal (4B5) |
| In order to report the demographic characteristics, recurrence pattern, and survival rate in Colombian females with breast cancer, Ventana HER2 antibody (Ventana, 4B5) was used in immunohistochemistry on human samples . Ecancermedicalscience (2015) ncbi |
| domestic rabbit monoclonal (4B5) |
| Ventana HER2 antibody (Ventana, 4B5) was used in immunohistochemistry - paraffin section on human samples (fig 6c). Oncotarget (2014) ncbi |
BD Biosciences
| mouse monoclonal (Neu 24.7) |
| BD Biosciences HER2 antibody (BD Biosciences, 340552) was used in flow cytometry on human samples at 1:50 (fig 2b, s14e). Sci Transl Med (2021) ncbi |
| mouse monoclonal (3B5) |
| BD Biosciences HER2 antibody (BD Biosciences, 554299) was used in mass cytometry on human samples (fig 3a). Cell (2019) ncbi |
| mouse monoclonal (42/c-erbB-2) |
| BD Biosciences HER2 antibody (BD, 610162) was used in western blot on human samples (fig 3a). Oncogene (2019) ncbi |
| mouse monoclonal (Neu 24.7) |
| BD Biosciences HER2 antibody (BD Biosciences, 340553) was used in flow cytometry on human samples (fig 2a). Cell Stress Chaperones (2017) ncbi |
| mouse monoclonal (Neu 24.7) |
| BD Biosciences HER2 antibody (Becton Dickinson, 340554) was used in immunocytochemistry on human samples at 1:20 (fig 5c). J Clin Invest (2017) ncbi |
| mouse monoclonal (Neu 24.7) |
| In order to suggest that EGFR promotes survival of prostate tumor-initiating cells and circulating tumor cells that metastasize to bone, whereas HER2 supports the growth of prostate cancer cells once they are established at metastatic sites, BD Biosciences HER2 antibody (B.D., Neu24.7) was used in flow cytometry on human samples at 1:133 (fig 4a). Cancer Res (2017) ncbi |
| mouse monoclonal (42/c-erbB-2) |
| In order to determine the effect of a mixture of two monoclonal antibodies against non-overlapping epitopes of HER2 on HER2 stability and localization, BD Biosciences HER2 antibody (BD Biosciences, 42) was used in western blot on human samples (fig 3b). J Cell Mol Med (2016) ncbi |
| mouse monoclonal (Neu 24.7) |
| In order to find cell-surface markers specific to human neutrophils, BD Biosciences HER2 antibody (BD, 340552) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi |
| mouse monoclonal (Neu 24.7) |
| BD Biosciences HER2 antibody (BD Biosciences, 340552) was used in flow cytometry on human samples at 1:50 (fig 1). Cell Death Dis (2016) ncbi |
| mouse monoclonal (9G6) |
| In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences HER2 antibody (BD, 9G6) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi |
| mouse monoclonal (3B5) |
| BD Biosciences HER2 antibody (BD Transduction, 554299) was used in immunocytochemistry on human samples at 1:100 and in western blot on human samples . Clin Exp Metastasis (2015) ncbi |
Leica Biosystems
| mouse monoclonal (CB11) |
| Leica Biosystems HER2 antibody (Novocastra, CB11) was used in immunohistochemistry - paraffin section on cat samples (fig 1c). Sci Rep (2020) ncbi |
| mouse monoclonal (CB11) |
| In order to investigate the use of altered double-strand break repair activities to classify breast cancers, Leica Biosystems HER2 antibody (Leica Biosystems, CB11) was used in immunocytochemistry on human samples at 1:500 (fig s1). FASEB J (2016) ncbi |
| mouse monoclonal (CB11) |
| Leica Biosystems HER2 antibody (Novocastra Laboratories, NCL-CB11) was used in immunohistochemistry - paraffin section on human samples at 1:200 (tbl 2). Braz J Med Biol Res (2016) ncbi |
| monoclonal |
| In order to evaluate the potential protein markers of bone metastases in breast cancer patients, Leica Biosystems HER2 antibody (Novocastra, NCL-L-CB11) was used in immunohistochemistry on human samples at 1:50. Pathol Oncol Res (2015) ncbi |
| mouse monoclonal (CB11) |
| Leica Biosystems HER2 antibody (Novocastra, NCL-CB11) was used in immunohistochemistry - paraffin section on human samples . J Clin Pathol (2015) ncbi |
Articles Reviewed
- Wang J, Zhang Y, Xiao Y, Yuan X, Li P, Wang X, et al. Boosting immune surveillance by low-dose PI3K inhibitor facilitates early intervention of breast cancer. Am J Cancer Res. 2021;11:2005-2024 pubmed
- Kundumani Sridharan V, Subramani J, Owens C, Das K. Nrg1β Released in Remote Ischemic Preconditioning Improves Myocardial Perfusion and Decreases Ischemia/Reperfusion Injury via ErbB2-Mediated Rescue of Endothelial Nitric Oxide Synthase and Abrogation of Trx2 Autophagy. Arterioscler Thromb Vasc Biol. 2021;41:2293-2314 pubmed publisher
- Greer Y, Gilbert S, Gril B, Narwal R, Peacock Brooks D, Tice D, et al. MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer. Breast Cancer Res. 2019;21:27 pubmed publisher
- Lloyd Lewis B, Davis F, Harris O, Hitchcock J, Lourenco F, Pasche M, et al. Imaging the mammary gland and mammary tumours in 3D: optical tissue clearing and immunofluorescence methods. Breast Cancer Res. 2016;18:127 pubmed
- Mitra S, Ghosh B, Gayen N, Roy J, Mandal A. Bipartite Role of Heat Shock Protein 90 (Hsp90) Keeps CRAF Kinase Poised for Activation. J Biol Chem. 2016;291:24579-24593 pubmed
- Deniz M, Kaufmann J, Stahl A, Gundelach T, Janni W, Hoffmann I, et al. In vitro model for DNA double-strand break repair analysis in breast cancer reveals cell type-specific associations with age and prognosis. FASEB J. 2016;30:3786-3799 pubmed
- Liu Y, Wang K, Xing H, Zhai X, Wang L, Wang W. Attempt towards a novel classification of triple-negative breast cancer using immunohistochemical markers. Oncol Lett. 2016;12:1240-1256 pubmed
- de Geus S, Boogerd L, Swijnenburg R, Mieog J, Tummers W, Prevoo H, et al. Selecting Tumor-Specific Molecular Targets in Pancreatic Adenocarcinoma: Paving the Way for Image-Guided Pancreatic Surgery. Mol Imaging Biol. 2016;18:807-819 pubmed
- KapucuoÄŸlu N, Bozkurt K, BaÅŸpınar Å, Koçer M, EroÄŸlu H, Akdeniz R, et al. The clinicopathological and prognostic significance of CD24, CD44, CD133, ALDH1 expressions in invasive ductal carcinoma of the breast: CD44/CD24 expression in breast cancer. Pathol Res Pract. 2015;211:740-7 pubmed publisher
- Hagrass H, Sharaf S, Pasha H, Tantawy E, Mohamed R, Kassem R. Circulating microRNAs - a new horizon in molecular diagnosis of breast cancer. Genes Cancer. 2015;6:281-7 pubmed
- Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed
- Hutchinson K, Johnson D, Johnson A, Sanchez V, Kuba M, Lu P, et al. ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma. Oncotarget. 2015;6:22348-60 pubmed
- Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt A, et al. Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies. Oncotarget. 2015;6:21522-32 pubmed
- Liu H, Du L, Wang R, Wei C, Liu B, Zhu L, et al. High frequency of loss of PTEN expression in human solid salivary adenoid cystic carcinoma and its implication for targeted therapy. Oncotarget. 2015;6:11477-91 pubmed
- Yardley D, Kaufman P, Huang W, Krekow L, Savin M, Lawler W, et al. Quantitative measurement of HER2 expression in breast cancers: comparison with 'real-world' routine HER2 testing in a multicenter Collaborative Biomarker Study and correlation with overall survival. Breast Cancer Res. 2015;17:41 pubmed publisher
- Ferreira R, Law M, Jahn S, Davis B, Heldermon C, Reinhard M, et al. Novel agents that downregulate EGFR, HER2, and HER3 in parallel. Oncotarget. 2015;6:10445-59 pubmed
- Cuello Carrión F, Shortrede J, Alvarez Olmedo D, Cayado Gutiérrez N, Castro G, Zoppino F, et al. HER2 and β-catenin protein location: importance in the prognosis of breast cancer patients and their correlation when breast cancer cells suffer stressful situations. Clin Exp Metastasis. 2015;32:151-68 pubmed publisher
- Hu S, Sun Y, Meng Y, Wang X, Yang W, Fu W, et al. Molecular architecture of the ErbB2 extracellular domain homodimer. Oncotarget. 2015;6:1695-706 pubmed
- Tu J, Yu Y, Liu W, Chen S. Significance of human epidermal growth factor receptor 2 expression in colorectal cancer. Exp Ther Med. 2015;9:17-24 pubmed
- Thomas G, Chardès T, Gaborit N, Mollevi C, Leconet W, Robert B, et al. HER3 as biomarker and therapeutic target in pancreatic cancer: new insights in pertuzumab therapy in preclinical models. Oncotarget. 2014;5:7138-48 pubmed
- Lerdrup M, Hommelgaard A, Grandal M, van Deurs B. Geldanamycin stimulates internalization of ErbB2 in a proteasome-dependent way. J Cell Sci. 2006;119:85-95 pubmed
- Traxler P, Allegrini P, Brandt R, Brueggen J, Cozens R, Fabbro D, et al. AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity. Cancer Res. 2004;64:4931-41 pubmed
articles
contribute
- If you are aware of any publication with knockout studies validating a monoclonal or recombinant antibody, either purchased from a supplier or developed by the author(s), please notify us through feedback.
questions and comments