This is a Validated Antibody Database (VAD) review about human HCN4, based on 10 published articles (read how Labome selects the articles), using HCN4 antibody in all methods. It is aimed to help Labome visitors find the most suited HCN4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HCN4 synonym: SSS2

Alomone Labs
domestic rabbit polyclonal
  • immunohistochemistry; shrews; 1:300; fig 2a
Alomone Labs HCN4 antibody (Alomone Labs, APC-052) was used in immunohistochemistry on shrews samples at 1:300 (fig 2a). Front Pharmacol (2021) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; rat; fig 4f
  • immunocytochemistry; rat; 1:200; loading ...; fig 4h
  • western blot; rat; 1:1000; fig 4d
Alomone Labs HCN4 antibody (Alomone, APC-052) was used in immunoprecipitation on rat samples (fig 4f), in immunocytochemistry on rat samples at 1:200 (fig 4h) and in western blot on rat samples at 1:1000 (fig 4d). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:250; fig 4b
Alomone Labs HCN4 antibody (Alomone labs, APC-052) was used in western blot on mouse samples at 1:250 (fig 4b). Int J Mol Sci (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; rat; 1:50; loading ...; fig 3a
In order to suggest that ectopic beats originating in the myocardial sleeves of the pulmonary veins occur only under pathological conditions, Alomone Labs HCN4 antibody (Alomone Labs, APC-052) was used in immunohistochemistry - frozen section on rat samples at 1:50 (fig 3a). Exp Ther Med (2016) ncbi
Invitrogen
rat monoclonal (SHG 1E5)
  • western blot; rat; 1:2000
In order to study burst-firing in TR neurons and spike-and-wave discharges in the Genetic Absence Epilepsy Rats from Strasbourg model, Invitrogen HCN4 antibody (Fisher, MA3-903) was used in western blot on rat samples at 1:2000. Pflugers Arch (2015) ncbi
StressMarq Biosciences
mouse monoclonal (N114/10 (Formerly sold as S114-10))
  • immunocytochemistry; domestic rabbit; 1:200; loading ...; fig 1
StressMarq Biosciences HCN4 antibody (StressMarq Biosciences, SMC-320D) was used in immunocytochemistry on domestic rabbit samples at 1:200 (fig 1). Ann Anat (2016) ncbi
Neuromab
mouse monoclonal (N114/10)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5
Neuromab HCN4 antibody (Neuromab, 75-150) was used in immunohistochemistry on mouse samples at 1:100 (fig 5). Int J Mol Sci (2021) ncbi
mouse monoclonal (N114/10)
  • immunohistochemistry - free floating section; mouse; 1:200; loading ...; tbl 1
Neuromab HCN4 antibody (NeuroMab, 75-150) was used in immunohistochemistry - free floating section on mouse samples at 1:200 (tbl 1). J Comp Neurol (2016) ncbi
mouse monoclonal (N114/10)
  • immunohistochemistry; mouse; fig s6
Neuromab HCN4 antibody (NeuroMab, N114.10) was used in immunohistochemistry on mouse samples (fig s6). Nature (2015) ncbi
mouse monoclonal (N114/10)
  • immunocytochemistry; mouse; 1:200; fig 1
In order to characterize the reprogramming of fibroblasts with cardiac transcription factors by induction of diverse cardiac cell types, Neuromab HCN4 antibody (NeuroMab, 75-150) was used in immunocytochemistry on mouse samples at 1:200 (fig 1). Development (2014) ncbi
mouse monoclonal (N114/10)
  • immunohistochemistry; rat
In order to investigate cyclic nucleotide-gated channel subunits in rat retinal ganglion cells, Neuromab HCN4 antibody (NeuroMab, 73-150) was used in immunohistochemistry on rat samples . J Comp Neurol (2011) ncbi
Articles Reviewed
  1. Zhong W, Darmani N. The HCN Channel Blocker ZD7288 Induces Emesis in the Least Shrew (Cryptotis parva). Front Pharmacol. 2021;12:647021 pubmed publisher
  2. Liu D, Song A, Qi X, van Vliet P, Xiao J, Xiong F, et al. Cohesin-protein Shugoshin-1 controls cardiac automaticity via HCN4 pacemaker channel. Nat Commun. 2021;12:2551 pubmed publisher
  3. Scherschel K, Bräuninger H, Mölders A, Erlenhardt N, Amin E, Jungen C, et al. Characterization of the HCN Interaction Partner TRIP8b/PEX5R in the Intracardiac Nervous System of TRIP8b-Deficient and Wild-Type Mice. Int J Mol Sci. 2021;22: pubmed publisher
  4. Xiao Y, Cai X, Atkinson A, Logantha S, Boyett M, Dobrzynski H. Expression of connexin 43, ion channels and Ca2+-handling proteins in rat pulmonary vein cardiomyocytes. Exp Ther Med. 2016;12:3233-3241 pubmed
  5. Inokaitis H, Pauziene N, Rysevaite Kyguoliene K, Pauza D. Innervation of sinoatrial nodal cells in the rabbit. Ann Anat. 2016;205:113-21 pubmed publisher
  6. Farshi P, Fyk Kolodziej B, Krolewski D, Walker P, Ichinose T. Dopamine D1 receptor expression is bipolar cell type-specific in the mouse retina. J Comp Neurol. 2016;524:2059-79 pubmed publisher
  7. Krishnaswamy A, Yamagata M, Duan X, Hong Y, Sanes J. Sidekick 2 directs formation of a retinal circuit that detects differential motion. Nature. 2015;524:466-470 pubmed publisher
  8. Nam Y, Lubczyk C, Bhakta M, Zang T, Fernandez Perez A, McAnally J, et al. Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors. Development. 2014;141:4267-78 pubmed publisher
  9. Cain S, Tyson J, Jones K, Snutch T. Thalamocortical neurons display suppressed burst-firing due to an enhanced Ih current in a genetic model of absence epilepsy. Pflugers Arch. 2015;467:1367-82 pubmed publisher
  10. Stradleigh T, Ogata G, Partida G, Oi H, Greenberg K, Krempely K, et al. Colocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cells. J Comp Neurol. 2011;519:2546-73 pubmed publisher