This is a Validated Antibody Database (VAD) review about human HCK, based on 4 published articles (read how Labome selects the articles), using HCK antibody in all methods. It is aimed to help Labome visitors find the most suited HCK antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HCK synonym: JTK9; p59Hck; p61Hck; tyrosine-protein kinase HCK; hematopoietic cell kinase; hemopoietic cell kinase; p59-HCK/p60-HCK
Abcam
rabbit polyclonal |
| In order to characterize a new specific pharmacological hematopoietic cell kinase inhibitor, Abcam HCK antibody (Abcam, ab61055) was used in western blot on human samples (fig 1d). Biochim Biophys Acta Mol Basis Dis (2017) ncbi |
rabbit monoclonal (EP2415Y) |
| In order to characterize a new specific pharmacological hematopoietic cell kinase inhibitor, Abcam HCK antibody (Abcam, ab75839) was used in western blot on human samples (fig 1d). Biochim Biophys Acta Mol Basis Dis (2017) ncbi |
Santa Cruz Biotechnology
mouse monoclonal (3D12E10) |
| In order to determine the response threshold of immunoreceptor tyrosine-based activation motifs, Santa Cruz Biotechnology HCK antibody (Santa Cruz, 1428) was used in immunoprecipitation on mouse samples (fig 9) and in western blot on mouse samples (fig 7). elife (2015) ncbi |
BD Biosciences
mouse monoclonal (18/Hck) |
| In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences HCK antibody (BD, 18) was used in other on human samples (fig st1) and in western blot on human samples (fig st4). Mol Cell Proteomics (2016) ncbi |
mouse monoclonal (18/Hck) |
| In order to elucidate the acquired motility and invasiveness of T. annulata-infected cells, BD Biosciences HCK antibody (BD, 610278) was used in western blot on cow samples at 1:1000 (fig 3b). PLoS Pathog (2014) ncbi |
Articles Reviewed
- Roversi F, Pericole F, Machado Neto J, da Silva Santos Duarte A, Longhini A, Corrocher F, et al. Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathway. Biochim Biophys Acta Mol Basis Dis. 2017;1863:450-461 pubmed publisher