This is a Validated Antibody Database (VAD) review about human HBB, based on 11 published articles (read how Labome selects the articles), using HBB antibody in all methods. It is aimed to help Labome visitors find the most suited HBB antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HBB synonym: CD113t-C; beta-globin; hemoglobin subunit beta; beta globin chain; hemoglobin, beta

Santa Cruz Biotechnology
mouse monoclonal (37-8)
  • western blot; human; loading ...; fig 2d
Santa Cruz Biotechnology HBB antibody (SantaCruz, sc-21757) was used in western blot on human samples (fig 2d). Stem Cells Transl Med (2018) ncbi
mouse monoclonal (37-8)
  • western blot; human; 1:2000; loading ...; fig 2a
Santa Cruz Biotechnology HBB antibody (Santa Cruz Biotechnology, SC-21757) was used in western blot on human samples at 1:2000 (fig 2a). Nat Commun (2017) ncbi
mouse monoclonal (37-8)
  • western blot; mouse; 1:1000; fig 4
In order to characterize modulation of retinal iron homeostasis by facilitating the update of transferrin-bound iron by alpha-synuclein which may be a visual manifestation of Parkinson's disease, Santa Cruz Biotechnology HBB antibody (Santa Cruz Biotechnology, sc-21757) was used in western blot on mouse samples at 1:1000 (fig 4). Free Radic Biol Med (2016) ncbi
mouse monoclonal (37-8)
  • western blot; human; 1:200; fig 7
Santa Cruz Biotechnology HBB antibody (santa Cruz, sc-21757) was used in western blot on human samples at 1:200 (fig 7). Biomed Res Int (2015) ncbi
mouse monoclonal (37-8)
  • flow cytometry; mouse; loading ...; fig 2
Santa Cruz Biotechnology HBB antibody (Santa Cruz, sc-21757) was used in flow cytometry on mouse samples (fig 2). Mol Ther Methods Clin Dev (2015) ncbi
mouse monoclonal (37-8)
  • western blot; scFv; fig 1
Santa Cruz Biotechnology HBB antibody (Santa Cruz, sc-21757) was used in western blot on scFv samples (fig 1). Mol Cell Biol (2015) ncbi
mouse monoclonal (37-8)
  • immunocytochemistry; human; 1:75
  • western blot; human; 1:100
Santa Cruz Biotechnology HBB antibody (Santa Cruz, SC-21757) was used in immunocytochemistry on human samples at 1:75 and in western blot on human samples at 1:100. Int J Oncol (2014) ncbi
mouse monoclonal (37-8)
  • western blot; human; 1:500
Santa Cruz Biotechnology HBB antibody (Santa Cruz, sc-21757) was used in western blot on human samples at 1:500. Exp Ther Med (2013) ncbi
mouse monoclonal (37-8)
  • flow cytometry; human
In order to describe a method to generate red blood cells ex vivo using human erythroid precursors, Santa Cruz Biotechnology HBB antibody (Santa Cruz Biotechnology, sc-21757) was used in flow cytometry on human samples . Mol Ther (2014) ncbi
Abcam
mouse polyclonal
  • immunocytochemistry; human; loading ...; fig 7b
  • western blot; human; loading ...; fig 7c
Abcam HBB antibody (Abcam, ab172019) was used in immunocytochemistry on human samples (fig 7b) and in western blot on human samples (fig 7c). PLoS ONE (2017) ncbi
Bio-Rad
human monoclonal (AbD05988)
  • western blot; human; 1:100
Bio-Rad HBB antibody (Serotec, HCA042) was used in western blot on human samples at 1:100. Int J Oncol (2014) ncbi
Proteintech Group
rabbit polyclonal
  • immunocytochemistry; mouse; fig 2
Proteintech Group HBB antibody (Proteintech, 16216-1-AP) was used in immunocytochemistry on mouse samples (fig 2). Sci Rep (2016) ncbi
Articles Reviewed
  1. Cai L, Bai H, Mahairaki V, Gao Y, He C, Wen Y, et al. A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease. Stem Cells Transl Med. 2018;7:87-97 pubmed publisher
  2. Trakarnsanga K, Griffiths R, Wilson M, Blair A, Satchwell T, Meinders M, et al. An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells. Nat Commun. 2017;8:14750 pubmed publisher
  3. Saha D, Koli S, Patgaonkar M, Reddy K. Expression of hemoglobin-α and β subunits in human vaginal epithelial cells and their functional significance. PLoS ONE. 2017;12:e0171084 pubmed publisher
  4. Baksi S, Tripathi A, Singh N. Alpha-synuclein modulates retinal iron homeostasis by facilitating the uptake of transferrin-bound iron: Implications for visual manifestations of Parkinson's disease. Free Radic Biol Med. 2016;97:292-306 pubmed publisher
  5. Chen I, Caprioli A, Ohnuki H, Kwak H, Porcher C, Tosato G. EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta. Sci Rep. 2016;6:27195 pubmed publisher
  6. Breveglieri G, Mancini I, Bianchi N, Lampronti I, Salvatori F, Fabbri E, et al. Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation. Biomed Res Int. 2015;2015:687635 pubmed publisher
  7. Romero Z, Campo Fernandez B, Wherley J, Kaufman M, Urbinati F, Cooper A, et al. The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells. Mol Ther Methods Clin Dev. 2015;2:15012 pubmed publisher
  8. Muniz L, Davidson L, West S. Poly(A) Polymerase and the Nuclear Poly(A) Binding Protein, PABPN1, Coordinate the Splicing and Degradation of a Subset of Human Pre-mRNAs. Mol Cell Biol. 2015;35:2218-30 pubmed publisher
  9. Emara M, Turner A, Allalunis Turner J. Adult, embryonic and fetal hemoglobin are expressed in human glioblastoma cells. Int J Oncol. 2014;44:514-20 pubmed publisher
  10. Peng L, Liu J, Li Y, Huang Z, Wang P, Gu Y, et al. Serum proteomics analysis and comparisons using iTRAQ in the progression of hepatitis B. Exp Ther Med. 2013;6:1169-1176 pubmed
  11. Huang X, Shah S, Wang J, Ye Z, Dowey S, Tsang K, et al. Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors. Mol Ther. 2014;22:451-463 pubmed publisher