This is a Validated Antibody Database (VAD) review about human H4, based on 38 published articles (read how Labome selects the articles), using H4 antibody in all methods. It is aimed to help Labome visitors find the most suited H4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
H4 synonym: FO108; H4; H4-16; H4/n; H4C1; H4C11; H4C12; H4C13; H4C15; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4F2; H4FN; HIST2H4; HIST2H4A

Abcam
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:100; loading ...; fig 6a
Abcam H4 antibody (abcam, ab9053) was used in immunocytochemistry on human samples at 1:100 (fig 6a). Int J Mol Sci (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 4b
Abcam H4 antibody (Abcam, ab46983) was used in western blot on human samples at 1:500 (fig 4b). Cell Death Dis (2019) ncbi
domestic rabbit polyclonal
  • western blot; brewer's yeast; 1:2000; loading ...; fig 3c
Abcam H4 antibody (Abcam, ab46983) was used in western blot on brewer's yeast samples at 1:2000 (fig 3c). J Vis Exp (2019) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:500; loading ...; fig 3c
Abcam H4 antibody (Abcam, ab9053) was used in immunocytochemistry on mouse samples at 1:500 (fig 3c). Cancer Res (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5a
Abcam H4 antibody (Abcam, ab17339) was used in western blot on human samples at 1:1000 (fig 5a). Cell Death Dis (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5a
Abcam H4 antibody (Abcam, ab5823) was used in western blot on human samples at 1:1000 (fig 5a). Cell Death Dis (2019) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 6a
Abcam H4 antibody (abcam, ab7311) was used in immunoprecipitation on human samples (fig 6a). Mol Cell Biol (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 7c
In order to examine the effects of the arginine methyltransferase PRMT5 on homologous recombination-mediated double-strand break repair, Abcam H4 antibody (Abcam, AB7311) was used in western blot on human samples (fig 7c). Mol Cell (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 4c
Abcam H4 antibody (Abcam, ab9053) was used in western blot on mouse samples (fig 4c). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 2b
Abcam H4 antibody (Abcam, ab9053) was used in chromatin immunoprecipitation on human samples (fig 2b). J Biol Chem (2017) ncbi
domestic rabbit polyclonal
  • other; human; 1:200; loading ...; fig 3
Abcam H4 antibody (Abcam, ab9052) was used in other on human samples at 1:200 (fig 3). Nat Chem Biol (2017) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 2e
Abcam H4 antibody (Abcam, ab9053) was used in chromatin immunoprecipitation on human samples (fig 2e). Nucleic Acids Res (2017) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 5c
In order to determine the molecular mechanisms that enable JAK2/signal transducer and activator of transcription 5 to access promoters of genes implicated in breast cancer pathogenesis, Abcam H4 antibody (Abcam, ab7311) was used in chromatin immunoprecipitation on human samples (fig 2b) and in western blot on human samples (fig 5c). J Biol Chem (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 4
Abcam H4 antibody (Abcam, AB7311) was used in western blot on mouse samples at 1:1000 (fig 4). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4b
In order to propose that acrolein alters chromatin assembly by reacting with lysine residues of histones, Abcam H4 antibody (Abcam, ab61238) was used in western blot on human samples (fig 4b). Mol Cell Biol (2016) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 2c
  • western blot; human; loading ...; fig 2c
Abcam H4 antibody (Abcam, ab5823) was used in chromatin immunoprecipitation on human samples (fig 2c) and in western blot on human samples (fig 2c). Oncogene (2017) ncbi
domestic rabbit polyclonal
  • western blot; brewer's yeast; fig 4C
In order to elucidate the interaction between Eaf3/5/7, NuA4, and RNA polymerase II, Abcam H4 antibody (Abcam, ab7311) was used in western blot on brewer's yeast samples (fig 4C). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig st3
In order to study the contribution of SFMBT2 to prostate cancer metastasis, Abcam H4 antibody (Abcam, ab9052) was used in chromatin immunoprecipitation on human samples (fig st3). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; fig 3
Abcam H4 antibody (Abcam, ab9053) was used in immunoprecipitation on human samples (fig 3). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; fig s4
Abcam H4 antibody (Abcam, 9053) was used in chromatin immunoprecipitation on human samples (fig s4). Cell Rep (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:500; fig 10
  • immunocytochemistry; mouse; 1:500; fig 10
Abcam H4 antibody (Abcam, ab9053) was used in immunocytochemistry on human samples at 1:500 (fig 10) and in immunocytochemistry on mouse samples at 1:500 (fig 10). elife (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:200; fig 3s1
In order to study zygotic genome activation and maternal LSD1/KDM1A as an essential regulator of chromatin and transcription landscapes, Abcam H4 antibody (Abcam, ab 9053) was used in immunocytochemistry on mouse samples at 1:200 (fig 3s1). elife (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; Entamoeba histolytica; 1:300; fig 3
  • western blot; Entamoeba histolytica; 1:2000
  • western blot; bovine; 1:2000
Abcam H4 antibody (Abcam, ab61238) was used in immunocytochemistry on Entamoeba histolytica samples at 1:300 (fig 3), in western blot on Entamoeba histolytica samples at 1:2000 and in western blot on bovine samples at 1:2000. Parasit Vectors (2016) ncbi
domestic rabbit polyclonal
  • western blot; bovine; 1:500; fig 2
  • immunocytochemistry; Entamoeba histolytica; 1:200; fig 3
  • western blot; Entamoeba histolytica; 1:500; fig 2
Abcam H4 antibody (Abcam, ab17339) was used in western blot on bovine samples at 1:500 (fig 2), in immunocytochemistry on Entamoeba histolytica samples at 1:200 (fig 3) and in western blot on Entamoeba histolytica samples at 1:500 (fig 2). Parasit Vectors (2016) ncbi
Invitrogen
mouse monoclonal (S.99.5)
  • western blot; human; 1:10,000; fig 2a
Invitrogen H4 antibody (Thermo Fisher Scientific, MA5-14816) was used in western blot on human samples at 1:10,000 (fig 2a). Sci Rep (2017) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 3e
In order to test if miR-29b suppresses histone deacetylases, Invitrogen H4 antibody (Thermo Fisher, PA1-84526) was used in chromatin immunoprecipitation on human samples (fig 3e). Mol Cancer Ther (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (6F8-D9)
  • other; human; 1:400; loading ...; fig 3
Santa Cruz Biotechnology H4 antibody (Santa Cruz, sc-134216) was used in other on human samples at 1:400 (fig 3). Nat Chem Biol (2017) ncbi
mouse monoclonal (6F8-D9)
  • immunohistochemistry - paraffin section; mouse
Santa Cruz Biotechnology H4 antibody (Santa Cruz Biotechnology, sc-134216) was used in immunohistochemistry - paraffin section on mouse samples . J Reprod Dev (2014) ncbi
Active Motif
domestic rabbit polyclonal
  • western blot; human; 1:5000; loading ...; fig 6a
Active Motif H4 antibody (Active Motif, 39167) was used in western blot on human samples at 1:5000 (fig 6a). elife (2020) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D84D2)
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology H4 antibody (Cell signaling, D84D2) was used in western blot on human samples at 1:1000 (fig 3b). Aging (Albany NY) (2019) ncbi
mouse monoclonal (L64C1)
  • western blot; mouse; loading ...; fig s1d
Cell Signaling Technology H4 antibody (Cell Signalling, L64C1) was used in western blot on mouse samples (fig s1d). Nucleic Acids Res (2019) ncbi
mouse monoclonal (L64C1)
  • western blot; mouse; loading ...; fig 3e
Cell Signaling Technology H4 antibody (Cell Signaling, 2935) was used in western blot on mouse samples (fig 3e). Cell (2019) ncbi
mouse monoclonal (L64C1)
  • western blot; human; loading ...; fig 1c
In order to study the role of ACK1/TNK2 in histone H4 Tyr88-phosphorylation and androgen receptor expression in prostate cancer, Cell Signaling Technology H4 antibody (Cell Signaling, 2935) was used in western blot on human samples (fig 1c). Cancer Cell (2017) ncbi
domestic rabbit monoclonal (D12B3)
  • chromatin immunoprecipitation; rat; loading ...; fig 7c
In order to research the role of HDAC9 in regulating kidney angiotensinogen expression, Cell Signaling Technology H4 antibody (Cell Signaling, 8647) was used in chromatin immunoprecipitation on rat samples (fig 7c). Biol Sex Differ (2017) ncbi
mouse monoclonal (L64C1)
  • western blot; mouse; loading ...; fig 5
Cell Signaling Technology H4 antibody (cell signalling, L64C1) was used in western blot on mouse samples (fig 5). J Cell Sci (2017) ncbi
domestic rabbit polyclonal
  • other; human; 1:100; loading ...; fig 3
Cell Signaling Technology H4 antibody (Cell Signal, 9724) was used in other on human samples at 1:100 (fig 3). Nat Chem Biol (2017) ncbi
domestic rabbit polyclonal
  • other; human; 1:1000; loading ...; fig s9
Cell Signaling Technology H4 antibody (Cell Signal, 2594) was used in other on human samples at 1:1000 (fig s9). Nat Chem Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...
In order to investigate the role of FACT in sensing DNA torsional stress, Cell Signaling Technology H4 antibody (Cell Signaling, 2592P) was used in western blot on human samples . Nucleic Acids Res (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1d
In order to investigate the mechanism by which vorinostat suppresses matrix metallopeptidase-13, Cell Signaling Technology H4 antibody (Cell Signaling, 2592) was used in western blot on human samples at 1:1000 (fig 1d). Am J Pathol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1d
In order to investigate the mechanism by which vorinostat suppresses matrix metallopeptidase-13, Cell Signaling Technology H4 antibody (Cell Signaling, 9672) was used in western blot on human samples at 1:1000 (fig 1d). Am J Pathol (2016) ncbi
domestic rabbit monoclonal (D84D2)
  • immunohistochemistry - paraffin section; human; fig 1
Cell Signaling Technology H4 antibody (Cell Signaling, cs5737) was used in immunohistochemistry - paraffin section on human samples (fig 1). Genome Biol (2016) ncbi
mouse monoclonal (L64C1)
  • western blot; human; loading ...; fig 2b
In order to show that FLCN regulates mTORC1 by modulating the leucine signal in lysosome, Cell Signaling Technology H4 antibody (Cell Signalling, 2935) was used in western blot on human samples (fig 2b). PLoS ONE (2016) ncbi
mouse monoclonal (L64C1)
  • western blot; rat
Cell Signaling Technology H4 antibody (Cell Signaling, 2935) was used in western blot on rat samples . PLoS ONE (2015) ncbi
mouse monoclonal (L64C1)
  • western blot; human
Cell Signaling Technology H4 antibody (Cell Signaling, 2935) was used in western blot on human samples . Eur Respir J (2014) ncbi
Articles Reviewed
  1. Wang Z, Millard C, Lin C, Gurnett J, Wu M, Lee K, et al. Diverse nucleosome site-selectivity among histone deacetylase complexes. elife. 2020;9: pubmed publisher
  2. Gil L, Niño S, Chi Ahumada E, Rodríguez Leyva I, Guerrero C, Rebolledo A, et al. Perinuclear Lamin A and Nucleoplasmic Lamin B2 Characterize Two Types of Hippocampal Neurons through Alzheimer's Disease Progression. Int J Mol Sci. 2020;21: pubmed publisher
  3. Perri A, Agosti V, Olivo E, Concolino A, Angelis M, Tammè L, et al. Histone proteomics reveals novel post-translational modifications in breast cancer. Aging (Albany NY). 2019;11:11722-11755 pubmed publisher
  4. Turberfield A, Kondo T, Nakayama M, Koseki Y, King H, Koseki H, et al. KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity. Nucleic Acids Res. 2019;47:9005-9023 pubmed publisher
  5. Shan C, Lu Z, Li Z, Sheng H, Fan J, Qi Q, et al. 4-hydroxyphenylpyruvate dioxygenase promotes lung cancer growth via pentose phosphate pathway (PPP) flux mediated by LKB1-AMPK/HDAC10/G6PD axis. Cell Death Dis. 2019;10:525 pubmed publisher
  6. Alim I, Caulfield J, Chen Y, Swarup V, Geschwind D, Ivanova E, et al. Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke. Cell. 2019;177:1262-1279.e25 pubmed publisher
  7. Bennett S, Cobos S, Meykler M, Fallah M, Rana N, Chen K, et al. Characterizing Histone Post-translational Modification Alterations in Yeast Neurodegenerative Proteinopathy Models. J Vis Exp. 2019;: pubmed publisher
  8. Li H, Petersen S, García Mariscal A, Brakebusch C. Negative Regulation of p53-Induced Senescence by N-WASP Is Crucial for DMBA/TPA-Induced Skin Tumor Formation. Cancer Res. 2019;79:2167-2181 pubmed publisher
  9. Demetriadou C, Pavlou D, Mpekris F, Achilleos C, Stylianopoulos T, Zaravinos A, et al. NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression. Cell Death Dis. 2019;10:236 pubmed publisher
  10. Fujimoto M, Takii R, Katiyar A, Srivastava P, Nakai A. Poly(ADP-Ribose) Polymerase 1 Promotes the Human Heat Shock Response by Facilitating Heat Shock Transcription Factor 1 Binding to DNA. Mol Cell Biol. 2018;38: pubmed publisher
  11. Parira T, Figueroa G, Laverde A, Casteleiro G, Gomez Hernandez M, FERNANDEZ LIMA F, et al. Novel detection of post-translational modifications in human monocyte-derived dendritic cells after chronic alcohol exposure: Role of inflammation regulator H4K12ac. Sci Rep. 2017;7:11236 pubmed publisher
  12. Mahajan K, Malla P, Lawrence H, Chen Z, Kumar Sinha C, Malik R, et al. ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer. Cancer Cell. 2017;31:790-803.e8 pubmed publisher
  13. Bourgeois C, Satou R, Prieto M. HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex difference. Biol Sex Differ. 2017;8:18 pubmed publisher
  14. Jha K, Tripurani S, Johnson G. TSSK6 is required for γH2AX formation and the histone-to-protamine transition during spermiogenesis. J Cell Sci. 2017;130:1835-1844 pubmed publisher
  15. Clarke T, Sanchez Bailon M, Chiang K, Reynolds J, Herrero Ruiz J, Bandeiras T, et al. PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination. Mol Cell. 2017;65:900-916.e7 pubmed publisher
  16. Wu N, Jia D, Bates B, Basom R, Eberhart C, MacPherson D. A mouse model of MYCN-driven retinoblastoma reveals MYCN-independent tumor reemergence. J Clin Invest. 2017;127:888-898 pubmed publisher
  17. Wang Y, Wang Y, Ma L, Nie M, Ju J, Liu M, et al. Heterochromatin Protein 1γ Is a Novel Epigenetic Repressor of Human Embryonic ϵ-Globin Gene Expression. J Biol Chem. 2017;292:4811-4817 pubmed publisher
  18. He Y, Selvaraju S, Curtin M, Jakob C, Zhu H, Comess K, et al. The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. Nat Chem Biol. 2017;13:389-395 pubmed publisher
  19. Asensio Juan E, Fueyo R, PAPPA S, Iacobucci S, Badosa C, Lois S, et al. The histone demethylase PHF8 is a molecular safeguard of the IFNγ response. Nucleic Acids Res. 2017;45:3800-3811 pubmed publisher
  20. Safina A, Cheney P, Pal M, Brodsky L, Ivanov A, Kirsanov K, et al. FACT is a sensor of DNA torsional stress in eukaryotic cells. Nucleic Acids Res. 2017;45:1925-1945 pubmed publisher
  21. Schauwecker S, Kim J, Licht J, Clevenger C. Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells. J Biol Chem. 2017;292:2237-2254 pubmed publisher
  22. Cooper S, Grijzenhout A, Underwood E, Ancelin K, Zhang T, Nesterova T, et al. Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2. Nat Commun. 2016;7:13661 pubmed publisher
  23. Fang L, Chen D, Yu C, Li H, Brocato J, Huang L, et al. Mechanisms Underlying Acrolein-Mediated Inhibition of Chromatin Assembly. Mol Cell Biol. 2016;36:2995-3008 pubmed publisher
  24. Makki M, Haqqi T. Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1?-Induced Matrix Metallopeptidase-13 Expression by Inhibiting IL-6 in Osteoarthritis Chondrocyte. Am J Pathol. 2016;186:2701-8 pubmed publisher
  25. Deng X, Shao G, Zhang H, Li C, Zhang D, Cheng L, et al. Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth. Oncogene. 2017;36:1223-1231 pubmed publisher
  26. Sathianathan A, Ravichandran P, Lippi J, Cohen L, Messina A, Shaju S, et al. The Eaf3/5/7 Subcomplex Stimulates NuA4 Interaction with Methylated Histone H3 Lys-36 and RNA Polymerase II. J Biol Chem. 2016;291:21195-21207 pubmed
  27. Nelson D, Jaber Hijazi F, Cole J, Robertson N, Pawlikowski J, Norris K, et al. Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biol. 2016;17:158 pubmed publisher
  28. Gwak J, Shin J, Lee K, Hong S, Oh S, Goh S, et al. SFMBT2 (Scm-like with four mbt domains 2) negatively regulates cell migration and invasion in prostate cancer cells. Oncotarget. 2016;7:48250-48264 pubmed publisher
  29. Woolnough J, Atwood B, Liu Z, Zhao R, Giles K. The Regulation of rRNA Gene Transcription during Directed Differentiation of Human Embryonic Stem Cells. PLoS ONE. 2016;11:e0157276 pubmed publisher
  30. Wu X, Zhao L, Chen Z, Ji X, Qiao X, Jin Y, et al. FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1. PLoS ONE. 2016;11:e0157100 pubmed publisher
  31. Amodio N, Stamato M, Gullà A, Morelli E, Romeo E, Raimondi L, et al. Therapeutic Targeting of miR-29b/HDAC4 Epigenetic Loop in Multiple Myeloma. Mol Cancer Ther. 2016;15:1364-75 pubmed publisher
  32. Huang C, Cheng J, Bawa Khalfe T, Yao X, Chin Y, Yeh E. SUMOylated ORC2 Recruits a Histone Demethylase to Regulate Centromeric Histone Modification and Genomic Stability. Cell Rep. 2016;15:147-157 pubmed publisher
  33. Sobecki M, Mrouj K, Camasses A, Parisis N, Nicolas E, Llères D, et al. The cell proliferation antigen Ki-67 organises heterochromatin. elife. 2016;5:e13722 pubmed publisher
  34. Ancelin K, Syx L, Borensztein M, Ranisavljevic N, Vassilev I, Briseño Roa L, et al. Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation. elife. 2016;5: pubmed publisher
  35. Lozano Amado D, Herrera Solorio A, Valdés J, Alemán Lazarini L, Almaraz Barrera M, Luna Rivera E, et al. Identification of repressive and active epigenetic marks and nuclear bodies in Entamoeba histolytica. Parasit Vectors. 2016;9:19 pubmed publisher
  36. Kim B, Serebreni L, Fallica J, Hamdan O, Wang L, Johnston L, et al. Cyclin-dependent kinase five mediates activation of lung xanthine oxidoreductase in response to hypoxia. PLoS ONE. 2015;10:e0124189 pubmed publisher
  37. Shirakata Y, Hiradate Y, Inoue H, Sato E, Tanemura K. Histone h4 modification during mouse spermatogenesis. J Reprod Dev. 2014;60:383-7 pubmed
  38. Sanders Y, Hagood J, Liu H, Zhang W, Ambalavanan N, Thannickal V. Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice. Eur Respir J. 2014;43:1448-58 pubmed publisher