This is a Validated Antibody Database (VAD) review about human Grb2, based on 24 published articles (read how Labome selects the articles), using Grb2 antibody in all methods. It is aimed to help Labome visitors find the most suited Grb2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Grb2 synonym: ASH; EGFRBP-GRB2; Grb3-3; MST084; MSTP084; NCKAP2; growth factor receptor-bound protein 2; HT027; SH2/SH3 adapter GRB2; abundant SRC homology; epidermal growth factor receptor-binding protein GRB2; growth factor receptor-bound protein 3; protein Ash

Santa Cruz Biotechnology
mouse monoclonal (E-1)
  • western blot; rat; loading ...
Santa Cruz Biotechnology Grb2 antibody (Santa Cruz, sc-17813) was used in western blot on rat samples . Front Neurosci (2016) ncbi
mouse monoclonal (C-7)
  • western blot; human; 1:200; fig 2
In order to study CD133+ subpopulations in pancreatic cancer, Santa Cruz Biotechnology Grb2 antibody (Santa Cruz, sc-8034) was used in western blot on human samples at 1:200 (fig 2). Oncol Lett (2016) ncbi
mouse monoclonal (1-68)
  • immunoprecipitation; human; fig 2g
  • immunocytochemistry; human; 1:500; fig s3h
  • western blot; human; 1:1000; fig 5a
Santa Cruz Biotechnology Grb2 antibody (Santa Cruz Biotechnology, sc-503) was used in immunoprecipitation on human samples (fig 2g), in immunocytochemistry on human samples at 1:500 (fig s3h) and in western blot on human samples at 1:1000 (fig 5a). Nat Commun (2016) ncbi
R&D Systems
mouse monoclonal (669604)
  • western blot; human; fig 4s3
In order to analyze Src homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases by time-resolved multimodal analysis, R&D Systems Grb2 antibody (R&D Systems, 669604) was used in western blot on human samples (fig 4s3). elife (2016) ncbi
mouse monoclonal (481021)
  • western blot; human
R&D Systems Grb2 antibody (R&D systems, MAB3846) was used in western blot on human samples . Biochem Biophys Res Commun (2014) ncbi
Abcam
rabbit monoclonal (Y301)
  • western blot; mouse; 1:2000
Abcam Grb2 antibody (Abcam, ab32111) was used in western blot on mouse samples at 1:2000. Acta Neuropathol (2015) ncbi
LifeSpan Biosciences
rabbit polyclonal
  • immunocytochemistry; human; fig s1
LifeSpan Biosciences Grb2 antibody (Lifespan Biosciences, LB-B4079) was used in immunocytochemistry on human samples (fig s1). J Cell Sci (2016) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; pig; fig 5
In order to investigate the protein profile of pseudorabies virus-infected PK15 cells using isobaric tags for relative and absolute quantification technology, Proteintech Group Grb2 antibody (Proteintech Group, 10254-2-AP) was used in western blot on pig samples (fig 5). Sci Rep (2017) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; loading ...; fig 4c
Cell Signaling Technology Grb2 antibody (Cell Signaling, 3972) was used in western blot on human samples (fig 4c). Cancer Res (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2a
In order to elucidate the role of SCIMP in Toll-like receptor signaling, Cell Signaling Technology Grb2 antibody (Cell Signaling, 3972) was used in western blot on mouse samples at 1:1000 (fig 2a). Nat Commun (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 8
Cell Signaling Technology Grb2 antibody (Cell Signaling Technology, 3972S) was used in western blot on human samples (fig 8). J Biol Chem (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 5
Cell Signaling Technology Grb2 antibody (Cell Signaling, 3972) was used in western blot on mouse samples (fig 5). Front Cell Neurosci (2016) ncbi
BD Biosciences
mouse monoclonal (81/GRB2)
  • immunocytochemistry; human; fig s12
In order to develop a new multiplex dSTORM imaging strategy to localize epitopes on activated T-cells, BD Biosciences Grb2 antibody (BD Biosciences, 610112) was used in immunocytochemistry on human samples (fig s12). Mol Biol Cell (2016) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; loading ...; fig 6b
In order to establish an integrated multilayered proteomics approach to study receptor signaling, BD Biosciences Grb2 antibody (BD Biosciences, 610111) was used in western blot on human samples (fig 6b). Nat Struct Mol Biol (2016) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human
BD Biosciences Grb2 antibody (Transduction Lab, 610111) was used in western blot on human samples . Sci Rep (2016) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; fig 4
In order to determine how sensitivity is restored in resistant ovarian cancer cells by targeting the Ras-MAPK pathway by miR-634, BD Biosciences Grb2 antibody (BD Pharmingen, 610111) was used in western blot on human samples (fig 4). Mol Cancer (2015) ncbi
mouse monoclonal (81/GRB2)
  • western blot; mouse; fig 1
  • western blot; human; fig 2
BD Biosciences Grb2 antibody (BD Bioscience, 610111) was used in western blot on mouse samples (fig 1) and in western blot on human samples (fig 2). Nat Med (2015) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; 1:1000; fig 2
BD Biosciences Grb2 antibody (BD Transduction Laboratories, 610112) was used in western blot on human samples at 1:1000 (fig 2). Oncotarget (2015) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; fig 3
BD Biosciences Grb2 antibody (BD Biosciences, 610112) was used in western blot on human samples (fig 3). Nat Commun (2015) ncbi
mouse monoclonal (81/GRB2)
  • western blot; mouse; fig 2
BD Biosciences Grb2 antibody (BD Bioscience, 610112) was used in western blot on mouse samples (fig 2). Cancer Res (2015) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; fig 4
BD Biosciences Grb2 antibody (BD Transduction, 610112) was used in western blot on human samples (fig 4). J Cell Sci (2015) ncbi
mouse monoclonal (81/GRB2)
  • western blot; mouse; 1:1000; fig 5D
BD Biosciences Grb2 antibody (BD, 610112) was used in western blot on mouse samples at 1:1000 (fig 5D). DNA Repair (Amst) (2015) ncbi
mouse monoclonal (81/GRB2)
  • immunoprecipitation; mouse; fig 7
  • western blot; mouse; 1:2000; fig 7
BD Biosciences Grb2 antibody (BD Transduction Laboratories, 610112) was used in immunoprecipitation on mouse samples (fig 7) and in western blot on mouse samples at 1:2000 (fig 7). PLoS ONE (2014) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; 1:2000
BD Biosciences Grb2 antibody (BD Biosciences, 610111) was used in western blot on human samples at 1:2000. FEBS Lett (2013) ncbi
Articles Reviewed
  1. Vaishnavi A, Schubert L, Rix U, Marek L, Le A, Keysar S, et al. EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases. Cancer Res. 2017;77:3551-3563 pubmed publisher
  2. Yang S, Pei Y, Zhao A. iTRAQ-based Proteomic Analysis of Porcine Kidney Epithelial PK15 cells Infected with Pseudorabies virus. Sci Rep. 2017;7:45922 pubmed publisher
  3. Luo L, Bokil N, Wall A, Kapetanovic R, Lansdaal N, Marceline F, et al. SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages. Nat Commun. 2017;8:14133 pubmed publisher
  4. Pandini G, Satriano C, Pietropaolo A, Gianì F, Travaglia A, La Mendola D, et al. The Inorganic Side of NGF: Copper(II) and Zinc(II) Affect the NGF Mimicking Signaling of the N-Terminus Peptides Encompassing the Recognition Domain of TrkA Receptor. Front Neurosci. 2016;10:569 pubmed publisher
  5. Yi J, Manna A, Barr V, Hong J, Neuman K, Samelson L. madSTORM: a superresolution technique for large-scale multiplexing at single-molecule accuracy. Mol Biol Cell. 2016;27:3591-3600 pubmed
  6. Sousa A, Rei M, Freitas R, Ricardo S, Caffrey T, David L, et al. Effect of MUC1/?-catenin interaction on the tumorigenic capacity of pancreatic CD133+ cells. Oncol Lett. 2016;12:1811-1817 pubmed
  7. Liu L, Phua Y, Lee R, Ma X, Jenkins Y, Novy K, et al. Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases. J Biol Chem. 2016;291:21571-21583 pubmed
  8. Daubon T, Spuul P, Alonso F, Fremaux I, Genot E. VEGF-A stimulates podosome-mediated collagen-IV proteolysis in microvascular endothelial cells. J Cell Sci. 2016;129:2586-98 pubmed publisher
  9. Francavilla C, Papetti M, Rigbolt K, Pedersen A, Sigurdsson J, Cazzamali G, et al. Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking. Nat Struct Mol Biol. 2016;23:608-18 pubmed publisher
  10. Jadwin J, Oh D, Curran T, Ogiue Ikeda M, Jia L, White F, et al. Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases. elife. 2016;5:e11835 pubmed publisher
  11. Osinalde N, Sánchez Quiles V, Blagoev B, Kratchmarova I. Changes in Gab2 phosphorylation and interaction partners in response to interleukin (IL)-2 stimulation in T-lymphocytes. Sci Rep. 2016;6:23530 pubmed publisher
  12. Zhang X, Peng D, Xi Y, Yuan C, Sagum C, Klein B, et al. G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression. Nat Commun. 2016;7:10810 pubmed publisher
  13. Balakrishnan S, Niebert M, Richter D. Rescue of Cyclic AMP Mediated Long Term Potentiation Impairment in the Hippocampus of Mecp2 Knockout (Mecp2(-/y) ) Mice by Rolipram. Front Cell Neurosci. 2016;10:15 pubmed publisher
  14. van Jaarsveld M, van Kuijk P, Boersma A, Helleman J, Van Ijcken W, Mathijssen R, et al. miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway. Mol Cancer. 2015;14:196 pubmed publisher
  15. Wen Q, Yang Q, Goldenson B, Malinge S, Lasho T, Schneider R, et al. Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition. Nat Med. 2015;21:1473-80 pubmed publisher
  16. Xing M, Wang X, Palmai Pallag T, Shen H, Helleday T, Hickson I, et al. Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response. Oncotarget. 2015;6:37638-46 pubmed publisher
  17. Capuani F, Conte A, Argenzio E, Marchetti L, Priami C, Polo S, et al. Quantitative analysis reveals how EGFR activation and downregulation are coupled in normal but not in cancer cells. Nat Commun. 2015;6:7999 pubmed publisher
  18. Kratochvill F, Gratz N, Qualls J, Van De Velde L, Chi H, Kovarik P, et al. Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner. Cancer Res. 2015;75:3054-64 pubmed publisher
  19. Parodi B, Rossi S, Morando S, Cordano C, Bragoni A, Motta C, et al. Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS. Acta Neuropathol. 2015;130:279-95 pubmed publisher
  20. Diesenberg K, Beerbaum M, Fink U, Schmieder P, Krauss M. SEPT9 negatively regulates ubiquitin-dependent downregulation of EGFR. J Cell Sci. 2015;128:397-407 pubmed publisher
  21. Uringa E, Baldeyron C, Odijk H, Wassenaar E, van Cappellen W, Maas A, et al. A mRad51-GFP antimorphic allele affects homologous recombination and DNA damage sensitivity. DNA Repair (Amst). 2015;25:27-40 pubmed publisher
  22. Tao W, Moore R, Smith E, Xu X. Hormonal induction and roles of Disabled-2 in lactation and involution. PLoS ONE. 2014;9:e110737 pubmed publisher
  23. Kim K, Lee S, Ryu S, Han D. Efficient isolation and elution of cellular proteins using aptamer-mediated protein precipitation assay. Biochem Biophys Res Commun. 2014;448:114-9 pubmed publisher
  24. Kodigepalli K, Dutta P, Bauckman K, Nanjundan M. SnoN/SkiL expression is modulated via arsenic trioxide-induced activation of the PI3K/AKT pathway in ovarian cancer cells. FEBS Lett. 2013;587:5-16 pubmed publisher