This is a Validated Antibody Database (VAD) review about human GSDME, based on 2 published articles (read how Labome selects the articles), using GSDME antibody in all methods. It is aimed to help Labome visitors find the most suited GSDME antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GSDME synonym: DFNA5; ICERE-1; gasdermin-E; DFNA5, deafness associated tumor suppressor; inversely correlated with estrogen receptor expression 1; non-syndromic hearing impairment protein 5; nonsyndromic hearing impairment protein

Knockout validation
Abcam
rabbit monoclonal (EPR19859)
  • western blot knockout validation; human; 1:1000; fig 4f
Abcam GSDME antibody (Abcam, ab215191) was used in western blot knockout validation on human samples at 1:1000 (fig 4f). Biochem Biophys Res Commun (2018) ncbi
Abcam
rabbit monoclonal (EPR19859)
  • western blot knockout validation; human; 1:1000; fig 4f
Abcam GSDME antibody (Abcam, ab215191) was used in western blot knockout validation on human samples at 1:1000 (fig 4f). Biochem Biophys Res Commun (2018) ncbi
Sigma-Aldrich
rabbit polyclonal
  • immunohistochemistry; African green monkey; 1:400; fig 5
In order to compare the expression of deafness genes in mice and the common marmoset, Sigma-Aldrich GSDME antibody (Sigma-Aldrich, HPA011326) was used in immunohistochemistry on African green monkey samples at 1:400 (fig 5). Sci Rep (2016) ncbi
Articles Reviewed
  1. Wang Y, Yin B, Li D, Wang G, Han X, Sun X. GSDME mediates caspase-3-dependent pyroptosis in gastric cancer. Biochem Biophys Res Commun. 2018;495:1418-1425 pubmed publisher
  2. Hosoya M, Fujioka M, Ogawa K, Okano H. Distinct Expression Patterns Of Causative Genes Responsible For Hereditary Progressive Hearing Loss In Non-Human Primate Cochlea. Sci Rep. 2016;6:22250 pubmed publisher