This is a Validated Antibody Database (VAD) review about human GPX2, based on 8 published articles (read how Labome selects the articles), using GPX2 antibody in all methods. It is aimed to help Labome visitors find the most suited GPX2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GPX2 synonym: GI-GPx; GPRP; GPRP-2; GPx-2; GPx-GI; GSHPX-GI; GSHPx-2; glutathione peroxidase 2; gastrointestinal glutathione peroxidase; glutathione peroxidase 2 (gastrointestinal); glutathione peroxidase-related protein 2

Santa Cruz Biotechnology
mouse monoclonal (E-7)
  • western blot; mouse; 1:500; loading ...; fig 5c
In order to propose that long-term quercetin consumption benefits the dystrophic heart, Santa Cruz Biotechnology GPX2 antibody (Santa Cruz Biotechnology, sc-74498) was used in western blot on mouse samples at 1:500 (fig 5c). Am J Physiol Heart Circ Physiol (2017) ncbi
mouse monoclonal (B-6)
  • western blot; human; loading ...; fig 9a
In order to present the effect thiosemicarbazones and inhibitors of thioredoxin reductase on mitochondrial peroxide defense, Santa Cruz Biotechnology GPX2 antibody (Santa Cruz, sc-133160) was used in western blot on human samples (fig 9a). Free Radic Biol Med (2016) ncbi
mouse monoclonal (E-7)
  • western blot; human; 1:300; fig s4
Santa Cruz Biotechnology GPX2 antibody (Santa Cruz, sc-74498) was used in western blot on human samples at 1:300 (fig s4). Redox Biol (2015) ncbi
mouse monoclonal (D-12)
  • western blot; mouse
In order to study the mechanism for 2-hydroxyethyl methacrylate-induced apoptosis, Santa Cruz Biotechnology GPX2 antibody (Santa Cruz, sc-133152) was used in western blot on mouse samples . Biomaterials (2014) ncbi
mouse monoclonal (B-6)
  • western blot; human
Santa Cruz Biotechnology GPX2 antibody (Santa Cruz Biotechnology, sc-133160) was used in western blot on human samples . J Biol Chem (2012) ncbi
Invitrogen
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; fig 2
  • western blot; human; 1:1000; fig 2
In order to assess the use of GPX2 as a biomarker for esophageal squamous cell carcinoma, Invitrogen GPX2 antibody (Thermo Fisher, PA5-27150) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2) and in western blot on human samples at 1:1000 (fig 2). BMC Cancer (2016) ncbi
Abcam
rabbit monoclonal (EPR8175(2))
  • western blot; mouse; loading ...; fig 7e
Abcam GPX2 antibody (Abcam, ab140130) was used in western blot on mouse samples (fig 7e). Mediators Inflamm (2016) ncbi
R&D Systems
mouse monoclonal (496010)
  • western blot; mouse; 1:200
R&D Systems GPX2 antibody (R&D Systems, MAB5470) was used in western blot on mouse samples at 1:200. Free Radic Biol Med (2015) ncbi
Articles Reviewed
  1. Geraghty P, Baumlin N, SALATHE M, Foronjy R, D Armiento J. Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure. Mediators Inflamm. 2016;2016:9461289 pubmed publisher
  2. Ballmann C, Denney T, Beyers R, Quindry T, Romero M, Amin R, et al. Lifelong quercetin enrichment and cardioprotection in Mdx/Utrn+/- mice. Am J Physiol Heart Circ Physiol. 2017;312:H128-H140 pubmed publisher
  3. Lei Z, Tian D, Zhang C, Zhao S, Su M. Clinicopathological and prognostic significance of GPX2 protein expression in esophageal squamous cell carcinoma. BMC Cancer. 2016;16:410 pubmed publisher
  4. Myers C. Enhanced targeting of mitochondrial peroxide defense by the combined use of thiosemicarbazones and inhibitors of thioredoxin reductase. Free Radic Biol Med. 2016;91:81-92 pubmed publisher
  5. Bagulho A, Vilas Boas F, Pena A, Peneda C, Santos F, Jerónimo A, et al. The extracellular matrix modulates H2O2 degradation and redox signaling in endothelial cells. Redox Biol. 2015;6:454-60 pubmed publisher
  6. Wang J, Shanmugam A, Markand S, Zorrilla E, Ganapathy V, Smith S. Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc(-), the Na(+)-independent glutamate-cystine exchanger. Free Radic Biol Med. 2015;86:25-36 pubmed publisher
  7. Schweikl H, Petzel C, Bolay C, Hiller K, Buchalla W, Krifka S. 2-Hydroxyethyl methacrylate-induced apoptosis through the ATM- and p53-dependent intrinsic mitochondrial pathway. Biomaterials. 2014;35:2890-904 pubmed publisher
  8. Wu C, Tang S, Wang P, Lee H, Ko J. Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation. J Biol Chem. 2012;287:25292-302 pubmed publisher