This is a Validated Antibody Database (VAD) review about human GPX1, based on 26 published articles (read how Labome selects the articles), using GPX1 antibody in all methods. It is aimed to help Labome visitors find the most suited GPX1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GPX1 synonym: GPXD; GSHPX1

Abcam
domestic rabbit monoclonal (EPR3312)
  • western blot; mouse; 1:500; loading ...; fig 5d
Abcam GPX1 antibody (Abcam, ab-108427) was used in western blot on mouse samples at 1:500 (fig 5d). Antioxidants (Basel) (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4f
Abcam GPX1 antibody (Abcam, ab22604) was used in western blot on mouse samples (fig 4f). Mol Metab (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; rat; loading ...; fig 7k
  • western blot; rat; 1:100; fig 7a
Abcam GPX1 antibody (Abcam, Ab22604) was used in immunohistochemistry on rat samples (fig 7k) and in western blot on rat samples at 1:100 (fig 7a). Aging (Albany NY) (2021) ncbi
domestic rabbit monoclonal (EPR3312)
  • immunoprecipitation; human; loading ...; fig 6d
  • western blot; human; 1:2000; loading ...; fig 6a
Abcam GPX1 antibody (Abcam, ab108427) was used in immunoprecipitation on human samples (fig 6d) and in western blot on human samples at 1:2000 (fig 6a). Mol Med Rep (2021) ncbi
domestic rabbit monoclonal (EPR3312)
  • western blot; human; loading ...; fig 6a
Abcam GPX1 antibody (Abcam, ab108427) was used in western blot on human samples (fig 6a). J Clin Invest (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 5e, 5s2c
Abcam GPX1 antibody (Abcam, ab22604) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 5e, 5s2c). elife (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 6d
Abcam GPX1 antibody (Abcam, Ab22604) was used in western blot on mouse samples (fig 6d). Cell (2018) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 5c
  • western blot; human; 1:100; loading ...; fig 5a
Abcam GPX1 antibody (Abcam, ab22604) was used in immunohistochemistry - paraffin section on human samples (fig 5c) and in western blot on human samples at 1:100 (fig 5a). Biochim Biophys Acta Proteins Proteom (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 2a
Abcam GPX1 antibody (Abcam, ab22604) was used in western blot on human samples (fig 2a). Placenta (2017) ncbi
domestic rabbit monoclonal (EPR3312)
  • western blot; human; 1:1000; loading ...; fig 3a
Abcam GPX1 antibody (Abcam, ab108427) was used in western blot on human samples at 1:1000 (fig 3a). Front Physiol (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; fig 5a
Abcam GPX1 antibody (Abcam, ab22604) was used in western blot on rat samples (fig 5a). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6a
In order to examine the changes to heat shock proteins after blood flow restricted exercise, Abcam GPX1 antibody (Abcam, ab22604) was used in western blot on human samples (fig 6a). Scand J Med Sci Sports (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 6
Abcam GPX1 antibody (Abcam, ab22604) was used in western blot on mouse samples (fig 6). Redox Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 3
Abcam GPX1 antibody (Abcam, ab22604) was used in western blot on mouse samples at 1:1000 (fig 3). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 4b
Abcam GPX1 antibody (Abcam, ab22604) was used in western blot on human samples at 1:1000 (fig 4b). Mol Med Rep (2016) ncbi
domestic rabbit monoclonal (EPR3311)
  • western blot; human; 1:1000
In order to measure nuclear and cytoplasmic protein abundances in human IMR90 fibroblasts subjected to mild oxidative stress using a subcellular spatial razor approach, Abcam GPX1 antibody (Abcam, ab108429) was used in western blot on human samples at 1:1000. J Proteome Res (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (E-7)
  • western blot; mouse; 1:500; loading ...; fig 5c
In order to propose that long-term quercetin consumption benefits the dystrophic heart, Santa Cruz Biotechnology GPX1 antibody (Santa Cruz Biotechnology, sc-74498) was used in western blot on mouse samples at 1:500 (fig 5c). Am J Physiol Heart Circ Physiol (2017) ncbi
mouse monoclonal (B-6)
  • western blot; human; loading ...; fig 9a
In order to present the effect thiosemicarbazones and inhibitors of thioredoxin reductase on mitochondrial peroxide defense, Santa Cruz Biotechnology GPX1 antibody (Santa Cruz, sc-133160) was used in western blot on human samples (fig 9a). Free Radic Biol Med (2016) ncbi
mouse monoclonal (E-7)
  • western blot; human; 1:300; fig s4
Santa Cruz Biotechnology GPX1 antibody (Santa Cruz, sc-74498) was used in western blot on human samples at 1:300 (fig s4). Redox Biol (2015) ncbi
mouse monoclonal (D-12)
  • western blot; mouse
In order to study the mechanism for 2-hydroxyethyl methacrylate-induced apoptosis, Santa Cruz Biotechnology GPX1 antibody (Santa Cruz, sc-133152) was used in western blot on mouse samples . Biomaterials (2014) ncbi
mouse monoclonal (B-6)
  • western blot; human
Santa Cruz Biotechnology GPX1 antibody (Santa Cruz Biotechnology, sc-133160) was used in western blot on human samples . J Biol Chem (2012) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C8C4)
Cell Signaling Technology GPX1 antibody (CST, 3286S) was used . Antioxidants (Basel) (2021) ncbi
domestic rabbit monoclonal (C8C4)
Cell Signaling Technology GPX1 antibody (Cell Signaling Technologies, 3286S) was used . J Virol (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5d
Cell Signaling Technology GPX1 antibody (Cell signaling, 3206) was used in western blot on human samples at 1:1000 (fig 5d). Front Physiol (2020) ncbi
domestic rabbit monoclonal (C8C4)
  • western blot; human
Cell Signaling Technology GPX1 antibody (Cell Signaling, 3286) was used in western blot on human samples . Am J Physiol Heart Circ Physiol (2013) ncbi
MBL International
  • western blot; African green monkey
MBL International GPX1 antibody (MBL, M015-3) was used in western blot on African green monkey samples . Proteomics (2014) ncbi
Articles Reviewed
  1. Wang L, Lavier J, Hua W, Wang Y, Gong L, Wei H, et al. High-Intensity Interval Training and Moderate-Intensity Continuous Training Attenuate Oxidative Damage and Promote Myokine Response in the Skeletal Muscle of ApoE KO Mice on High-Fat Diet. Antioxidants (Basel). 2021;10: pubmed publisher
  2. Hauffe R, Rath M, Schell M, Ritter K, Kappert K, Deubel S, et al. HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue. Mol Metab. 2021;53:101276 pubmed publisher
  3. Garcia Mesa Y, Xu H, Vance P, Gruenewald A, Garza R, Midkiff C, et al. Dimethyl Fumarate, an Approved Multiple Sclerosis Treatment, Reduces Brain Oxidative Stress in SIV-Infected Rhesus Macaques: Potential Therapeutic Repurposing for HIV Neuroprotection. Antioxidants (Basel). 2021;10: pubmed publisher
  4. Huang Y, Xiao X, Xiao H, Hu Z, Tan F. CUEDC2 ablation enhances the efficacy of mesenchymal stem cells in ameliorating cerebral ischemia/reperfusion insult. Aging (Albany NY). 2021;13:4335-4356 pubmed publisher
  5. Zhang X, Zhao H, Wang Y, Di L, Liu X, Qian F, et al. Zenglv Fumai Granule protects cardiomyocytes against hypoxia/reoxygenation-induced apoptosis via inhibiting TRIM28 expression. Mol Med Rep. 2021;23: pubmed publisher
  6. Garcia Mesa Y, Garza R, Diaz Ortiz M, Gruenewald A, Bastien B, Lobrovich R, et al. Regional Brain Recovery from Acute Synaptic Injury in Simian Immunodeficiency Virus-Infected Rhesus Macaques Associates with Heme Oxygenase Isoform Expression. J Virol. 2020;94: pubmed publisher
  7. Arc Chagnaud C, Py G, Fovet T, Roumanille R, Demangel R, Pagano A, et al. Evaluation of an Antioxidant and Anti-inflammatory Cocktail Against Human Hypoactivity-Induced Skeletal Muscle Deconditioning. Front Physiol. 2020;11:71 pubmed publisher
  8. Pan C, Jin L, Wang X, Li Y, Chun J, Boese A, et al. Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance. J Clin Invest. 2019;129:2431-2445 pubmed publisher
  9. Basnet H, Tian L, Ganesh K, Huang Y, Macalinao D, Brogi E, et al. Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization. elife. 2019;8: pubmed publisher
  10. Ingold I, Berndt C, Schmitt S, Doll S, Poschmann G, Buday K, et al. Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis. Cell. 2018;172:409-422.e21 pubmed publisher
  11. Jin X, Xu Z, Cao J, Shao P, Zhou M, Qin Z, et al. Proteomics analysis of human placenta reveals glutathione metabolism dysfunction as the underlying pathogenesis for preeclampsia. Biochim Biophys Acta Proteins Proteom. 2017;1865:1207-1214 pubmed publisher
  12. Li M, Cheng W, Luo J, Hu X, Nie T, Lai H, et al. Loss of selenocysteine insertion sequence binding protein 2 suppresses the proliferation, migration/invasion and hormone secretion of human trophoblast cells via the PI3K/Akt and ERK signaling pathway. Placenta. 2017;55:81-89 pubmed publisher
  13. Ahn B, Coblentz P, Beharry A, Patel N, Judge A, Moylan J, et al. Diaphragm Abnormalities in Patients with End-Stage Heart Failure: NADPH Oxidase Upregulation and Protein Oxidation. Front Physiol. 2016;7:686 pubmed publisher
  14. Ballmann C, Denney T, Beyers R, Quindry T, Romero M, Amin R, et al. Lifelong quercetin enrichment and cardioprotection in Mdx/Utrn+/- mice. Am J Physiol Heart Circ Physiol. 2017;312:H128-H140 pubmed publisher
  15. Dubey A, Copeland P. The Selenocysteine-Specific Elongation Factor Contains Unique Sequences That Are Required for Both Nuclear Export and Selenocysteine Incorporation. PLoS ONE. 2016;11:e0165642 pubmed publisher
  16. Cumming K, Ellefsen S, Rønnestad B, Ugelstad I, Raastad T. Acute and long-term effects of blood flow restricted training on heat shock proteins and endogenous antioxidant systems. Scand J Med Sci Sports. 2017;27:1190-1201 pubmed publisher
  17. Shanmugam G, Narasimhan M, Sakthivel R, Kumar R R, Davidson C, Palaniappan S, et al. A biphasic effect of TNF-? in regulation of the Keap1/Nrf2 pathway in cardiomyocytes. Redox Biol. 2016;9:77-89 pubmed publisher
  18. Tweedie D, Fukui K, Li Y, Yu Q, Barak S, Tamargo I, et al. Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms. PLoS ONE. 2016;11:e0156493 pubmed publisher
  19. Li B, Guo W, Hong L, Liu Y, Liu C, Hong S, et al. Role of mechanical strain-activated PI3K/Akt signaling pathway in pelvic organ prolapse. Mol Med Rep. 2016;14:243-53 pubmed publisher
  20. Myers C. Enhanced targeting of mitochondrial peroxide defense by the combined use of thiosemicarbazones and inhibitors of thioredoxin reductase. Free Radic Biol Med. 2016;91:81-92 pubmed publisher
  21. Bagulho A, Vilas Boas F, Pena A, Peneda C, Santos F, Jerónimo A, et al. The extracellular matrix modulates H2O2 degradation and redox signaling in endothelial cells. Redox Biol. 2015;6:454-460 pubmed publisher
  22. Baqader N, Radulovic M, Crawford M, Stoeber K, Godovac Zimmermann J. Nuclear cytoplasmic trafficking of proteins is a major response of human fibroblasts to oxidative stress. J Proteome Res. 2014;13:4398-423 pubmed publisher
  23. Kim S, Lee S, Lee S, Park J, Ryu D. Arsenite-induced changes in hepatic protein abundance in cynomolgus monkeys (Macaca fascicularis). Proteomics. 2014;14:1833-43 pubmed publisher
  24. Schweikl H, Petzel C, Bolay C, Hiller K, Buchalla W, Krifka S. 2-Hydroxyethyl methacrylate-induced apoptosis through the ATM- and p53-dependent intrinsic mitochondrial pathway. Biomaterials. 2014;35:2890-904 pubmed publisher
  25. Stride N, Larsen S, Hey Mogensen M, Hansen C, Prats C, Steinbruchel D, et al. Impaired mitochondrial function in chronically ischemic human heart. Am J Physiol Heart Circ Physiol. 2013;304:H1407-14 pubmed publisher
  26. Wu C, Tang S, Wang P, Lee H, Ko J. Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation. J Biol Chem. 2012;287:25292-302 pubmed publisher