This is a Validated Antibody Database (VAD) review about human GLRA1, based on 5 published articles (read how Labome selects the articles), using GLRA1 antibody in all methods. It is aimed to help Labome visitors find the most suited GLRA1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GLRA1 synonym: HKPX1; STHE; glycine receptor subunit alpha-1; glycine receptor 48 kDa subunit; glycine receptor strychnine-binding subunit

Synaptic Systems
mouse monoclonal (mAb4a)
  • western blot; mouse; 1:500; loading ...; fig 2a
Synaptic Systems GLRA1 antibody (Synaptic Systems, 146 011) was used in western blot on mouse samples at 1:500 (fig 2a). J Neurosci (2017) ncbi
mouse monoclonal (mAb2b)
  • immunohistochemistry - frozen section; mouse; 1:250; loading ...; fig 4a
Synaptic Systems GLRA1 antibody (Synaptic Systems, 146 111) was used in immunohistochemistry - frozen section on mouse samples at 1:250 (fig 4a). J Neurosci (2017) ncbi
mouse monoclonal (mAb4a)
  • immunocytochemistry; human; 1:500; loading ...; fig 5a
  • western blot; human; loading ...; fig 6a
Synaptic Systems GLRA1 antibody (SYSY, MAb4a) was used in immunocytochemistry on human samples at 1:500 (fig 5a) and in western blot on human samples (fig 6a). J Neurochem (2017) ncbi
mouse monoclonal (mAb4a)
  • western blot; rat; 1:1000; fig 2h
Synaptic Systems GLRA1 antibody (Synaptic Systems, mAb4a) was used in western blot on rat samples at 1:1000 (fig 2h). Eneuro (2017) ncbi
mouse monoclonal (mAb2b)
  • immunocytochemistry; rat; fig 2b
Synaptic Systems GLRA1 antibody (Synaptic Systems, 146-111) was used in immunocytochemistry on rat samples (fig 2b). Eneuro (2017) ncbi
mouse monoclonal (mAb4a)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1a
  • immunohistochemistry; mouse
Synaptic Systems GLRA1 antibody (Synaptic Systems, mAb4a) was used in immunohistochemistry - frozen section on mouse samples (fig 1a) and in immunohistochemistry on mouse samples . Hear Res (2016) ncbi
Invitrogen
rabbit polyclonal
  • immunohistochemistry; human; 1:1000; fig 3
In order to analyze the extracellular domain of cys-loop receptors and the role of an absolutely conserved tryptophan pair, Invitrogen GLRA1 antibody (ThermoFisher, PA1-4661) was used in immunohistochemistry on human samples at 1:1000 (fig 3). ACS Chem Neurosci (2016) ncbi
Articles Reviewed
  1. Schaefer N, Berger A, van Brederode J, Zheng F, Zhang Y, Leacock S, et al. Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease. J Neurosci. 2017;37:7948-7961 pubmed publisher
  2. Langlhofer G, Villmann C. The role of charged residues in independent glycine receptor folding domains for intermolecular interactions and ion channel function. J Neurochem. 2017;142:41-55 pubmed publisher
  3. Nakahata Y, Eto K, Murakoshi H, Watanabe M, Kuriu T, Hirata H, et al. Activation-Dependent Rapid Postsynaptic Clustering of Glycine Receptors in Mature Spinal Cord Neurons. Eneuro. 2017;4: pubmed publisher
  4. Dlugaiczyk J, Hecker D, Neubert C, Buerbank S, Campanelli D, Becker C, et al. Loss of glycine receptors containing the α3 subunit compromises auditory nerve activity, but not outer hair cell function. Hear Res. 2016;337:25-34 pubmed publisher
  5. Braun N, Lynagh T, Yu R, Biggin P, Pless S. Role of an Absolutely Conserved Tryptophan Pair in the Extracellular Domain of Cys-Loop Receptors. ACS Chem Neurosci. 2016;7:339-48 pubmed publisher