This is a Validated Antibody Database (VAD) review about human GLI2, based on 18 published articles (read how Labome selects the articles), using GLI2 antibody in all methods. It is aimed to help Labome visitors find the most suited GLI2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GLI2 synonym: CJS; HPE9; PHS2; THP1; THP2; zinc finger protein GLI2; GLI family zinc finger protein 2; GLI-Kruppel family member GLI2; glioma-associated oncogene family zinc finger 2; oncogene GLI2; tax helper protein 1; tax helper protein 2; tax-responsive element-2 holding protein; tax-responsive element-25-bp sequence binding protein

Abcam
rabbit polyclonal
  • immunocytochemistry; mouse; 1:100; fig 8
Abcam GLI2 antibody (abcam, ab167389) was used in immunocytochemistry on mouse samples at 1:100 (fig 8). Nat Commun (2016) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; fig 5
  • western blot; human; fig s5
Abcam GLI2 antibody (Abcam, ab26056) was used in chromatin immunoprecipitation on human samples (fig 5) and in western blot on human samples (fig s5). Cell Death Dis (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100
Abcam GLI2 antibody (Abcam, ab26056) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. Cell Death Dis (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Abcam GLI2 antibody (Abcam, ab26056) was used in western blot on human samples (fig 5). Cell Signal (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:100
Abcam GLI2 antibody (Abcam, AB26056) was used in immunocytochemistry on mouse samples at 1:100. Toxicol Appl Pharmacol (2014) ncbi
rabbit polyclonal
  • immunoprecipitation; human; fig 3
  • western blot; human; fig 2
In order to elucidate the contribution of lncRNA BCAR4 in breast cancer metastasis, Abcam GLI2 antibody (Abcam, ab26056) was used in immunoprecipitation on human samples (fig 3) and in western blot on human samples (fig 2). Cell (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 2
  • western blot; mouse; 1:1000; fig 2
In order to report a regulatory role for the Ptc1-Gli1 complex in adult neural circuit integrity of the brain, Abcam GLI2 antibody (Abcam, ab26056) was used in western blot on human samples at 1:1000 (fig 2) and in western blot on mouse samples at 1:1000 (fig 2). Hum Mol Genet (2014) ncbi
rabbit polyclonal
  • western blot; fruit fly
Abcam GLI2 antibody (Abcam, ab26056) was used in western blot on fruit fly samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human
Abcam GLI2 antibody (Abcam, ab26056) was used in western blot on human samples . Biol Pharm Bull (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
Abcam GLI2 antibody (Abcam, ab26056) was used in western blot on mouse samples at 1:1000. Differentiation (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; human
  • western blot; human
Abcam GLI2 antibody (Abcam, ab26056) was used in immunocytochemistry on human samples and in western blot on human samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:200
Abcam GLI2 antibody (Abcam, ab26056) was used in immunocytochemistry on mouse samples at 1:200. Genomics (2013) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:200
Abcam GLI2 antibody (Abcam, ab26056) was used in immunocytochemistry on human samples at 1:200. Oncogene (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human
Abcam GLI2 antibody (Abcam, Ab26056) was used in immunohistochemistry - paraffin section on human samples . Am J Pathol (2012) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-10)
  • immunocytochemistry; mouse; 1:100; loading ...; fig 2g
Santa Cruz Biotechnology GLI2 antibody (Santa Cruz Biotechnology, sc-271786) was used in immunocytochemistry on mouse samples at 1:100 (fig 2g). PLoS ONE (2017) ncbi
mouse monoclonal (C-10)
  • western blot; human; 1:1000; loading ...; fig s9c
Santa Cruz Biotechnology GLI2 antibody (Santa Cruz, sc-271786) was used in western blot on human samples at 1:1000 (fig s9c). Science (2016) ncbi
mouse monoclonal (C-10)
  • chromatin immunoprecipitation; human; fig 5
Santa Cruz Biotechnology GLI2 antibody (Santa Cruz, sc-271786) was used in chromatin immunoprecipitation on human samples (fig 5). Cell Death Dis (2016) ncbi
mouse monoclonal (C-10)
  • western blot; human; fig 4a
Santa Cruz Biotechnology GLI2 antibody (Santa Cruz Biotechnology, sc-271786) was used in western blot on human samples (fig 4a). Oncotarget (2015) ncbi
mouse monoclonal (C-10)
  • western blot; mouse; loading ...; fig 1a
  • western blot; human; fig 4b
Santa Cruz Biotechnology GLI2 antibody (Santa, SC-271786) was used in western blot on mouse samples (fig 1a) and in western blot on human samples (fig 4b). Neoplasia (2015) ncbi
mouse monoclonal (C-10)
  • immunohistochemistry - paraffin section; mouse; 1:400
  • western blot; mouse; 1:200
Santa Cruz Biotechnology GLI2 antibody (Santa Cruz, SC-271786) was used in immunohistochemistry - paraffin section on mouse samples at 1:400 and in western blot on mouse samples at 1:200. Toxicol Appl Pharmacol (2014) ncbi
R&D Systems
sheep polyclonal
  • chromatin immunoprecipitation; human; fig 4
In order to elucidate the contribution of lncRNA BCAR4 in breast cancer metastasis, R&D Systems GLI2 antibody (R&D, AF3526) was used in chromatin immunoprecipitation on human samples (fig 4). Cell (2014) ncbi
Articles Reviewed
  1. Drannik A, MARTIN J, Peterson R, Ma X, Jiang F, Turnbull J. Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function. PLoS ONE. 2017;12:e0171668 pubmed publisher
  2. Yan B, Zhang Z, Jin D, Cai C, Jia C, Liu W, et al. mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation. Nat Commun. 2016;7:11151 pubmed publisher
  3. Pattabiraman D, Bierie B, Kober K, Thiru P, Krall J, Zill C, et al. Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science. 2016;351:aad3680 pubmed publisher
  4. Vlčková K, Ondrušová L, Vachtenheim J, Réda J, Dundr P, Zadinová M, et al. Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cells. Cell Death Dis. 2016;7:e2048 pubmed publisher
  5. Inaguma S, Ito H, Riku M, Ikeda H, Kasai K. Addiction of pancreatic cancer cells to zinc-finger transcription factor ZIC2. Oncotarget. 2015;6:28257-68 pubmed publisher
  6. Bora Singhal N, Perumal D, Nguyen J, Chellappan S. Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer. Neoplasia. 2015;17:538-51 pubmed publisher
  7. Pan Y, Gong Y, Ruan H, Pan L, Wu X, Tang C, et al. Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth. Cell Death Dis. 2015;6:e1653 pubmed publisher
  8. Tang C, Pan Y, Luo H, Xiong W, Zhu H, Ruan H, et al. Hedgehog signaling stimulates the conversion of cholesterol to steroids. Cell Signal. 2015;27:487-97 pubmed publisher
  9. Liu J, Bain L. Arsenic inhibits hedgehog signaling during P19 cell differentiation. Toxicol Appl Pharmacol. 2014;281:243-53 pubmed publisher
  10. Xing Z, Lin A, Li C, Liang K, Wang S, Liu Y, et al. lncRNA directs cooperative epigenetic regulation downstream of chemokine signals. Cell. 2014;159:1110-1125 pubmed publisher
  11. He P, Staufenbiel M, Li R, Shen Y. Deficiency of patched 1-induced Gli1 signal transduction results in astrogenesis in Swedish mutated APP transgenic mice. Hum Mol Genet. 2014;23:6512-27 pubmed publisher
  12. Shahi M, Holt R, Rebhun R. Blocking signaling at the level of GLI regulates downstream gene expression and inhibits proliferation of canine osteosarcoma cells. PLoS ONE. 2014;9:e96593 pubmed publisher
  13. Matsumoto T, Tabata K, Suzuki T. The GANT61, a GLI inhibitor, induces caspase-independent apoptosis of SK-N-LO cells. Biol Pharm Bull. 2014;37:633-41 pubmed
  14. Romani S, Illi B, De Mori R, Savino M, Gleeson J, Valente E. The ciliary proteins Meckelin and Jouberin are required for retinoic acid-dependent neural differentiation of mouse embryonic stem cells. Differentiation. 2014;87:134-146 pubmed publisher
  15. Chen Q, Xu R, Zeng C, Lu Q, Huang D, Shi C, et al. Down-regulation of Gli transcription factor leads to the inhibition of migration and invasion of ovarian cancer cells via integrin ?4-mediated FAK signaling. PLoS ONE. 2014;9:e88386 pubmed publisher
  16. Li Y, Drnevich J, Akraiko T, Band M, Li D, Wang F, et al. Gene expression profiling reveals the heterogeneous transcriptional activity of Oct3/4 and its possible interaction with Gli2 in mouse embryonic stem cells. Genomics. 2013;102:456-67 pubmed publisher
  17. Bosco Clément G, Zhang F, Chen Z, Zhou H, Li H, Mikami I, et al. Targeting Gli transcription activation by small molecule suppresses tumor growth. Oncogene. 2014;33:2087-97 pubmed publisher
  18. Cigna N, Farrokhi Moshai E, Brayer S, Marchal Sommé J, Wemeau Stervinou L, Fabre A, et al. The hedgehog system machinery controls transforming growth factor-?-dependent myofibroblastic differentiation in humans: involvement in idiopathic pulmonary fibrosis. Am J Pathol. 2012;181:2126-37 pubmed publisher