This is a Validated Antibody Database (VAD) review about human GGA2, based on 7 published articles (read how Labome selects the articles), using GGA2 antibody in all methods. It is aimed to help Labome visitors find the most suited GGA2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GGA2 synonym: VEAR; ADP-ribosylation factor-binding protein GGA2; VHS domain and ear domain of gamma-adaptin; VHS domain and ear domain-containing protein; gamma-adaptin-related protein 2; golgi-localized, gamma ear-containing, ARF-binding protein 2

Sigma-Aldrich
mouse monoclonal (100/3)
  • immunocytochemistry; human; fig 2
Sigma-Aldrich GGA2 antibody (Sigma, 100/3) was used in immunocytochemistry on human samples (fig 2). J Biol Chem (2016) ncbi
mouse monoclonal (100/3)
  • immunocytochemistry; human; 1:100
In order to study the conversion of phosphatidylinositol 3-phosphate to phosphatidylinositol 4-phosphate at endosomes en route to the plasma membrane, Sigma-Aldrich GGA2 antibody (Sigma-Aldrich, 100/3) was used in immunocytochemistry on human samples at 1:100. Nature (2016) ncbi
mouse monoclonal (100/3)
  • immunocytochemistry; human; loading ...; fig 3f
In order to present the role of cathepsin D and its newly identified transport receptor SEZ6L2 on neurite outgrowth, Sigma-Aldrich GGA2 antibody (Sigma, 100/3) was used in immunocytochemistry on human samples (fig 3f). J Cell Sci (2016) ncbi
mouse monoclonal (100/3)
  • immunohistochemistry; mouse; fig s4
In order to investigate the role of BLOC-2 in endosomal tubular transport in melanosomes, Sigma-Aldrich GGA2 antibody (SIGMA, clone 100/3) was used in immunohistochemistry on mouse samples (fig s4). J Cell Biol (2015) ncbi
mouse monoclonal (100/3)
  • immunocytochemistry; African green monkey; fig 2
  • western blot; African green monkey; fig 4
Sigma-Aldrich GGA2 antibody (Sigma, A4200) was used in immunocytochemistry on African green monkey samples (fig 2) and in western blot on African green monkey samples (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (100/3)
  • immunocytochemistry; human; fig 5
In order to characterize the rabaptin-5gamma isoform, Sigma-Aldrich GGA2 antibody (Sigma, 100/3) was used in immunocytochemistry on human samples (fig 5). Biochemistry (Mosc) (2014) ncbi
BD Biosciences
mouse monoclonal (27/GGA2)
  • immunocytochemistry; rat; fig s4
  • western blot; human; fig 2
  • western blot; mouse; fig 5
BD Biosciences GGA2 antibody (BD, 612612) was used in immunocytochemistry on rat samples (fig s4), in western blot on human samples (fig 2) and in western blot on mouse samples (fig 5). PLoS ONE (2015) ncbi
Articles Reviewed
  1. Schütz I, López Hernández T, Gao Q, Puchkov D, Jabs S, Nordmeyer D, et al. Lysosomal Dysfunction Caused by Cellular Accumulation of Silica Nanoparticles. J Biol Chem. 2016;291:14170-84 pubmed publisher
  2. Ketel K, Krauss M, Nicot A, Puchkov D, Wieffer M, Müller R, et al. A phosphoinositide conversion mechanism for exit from endosomes. Nature. 2016;529:408-12 pubmed publisher
  3. Boonen M, Staudt C, Gilis F, Oorschot V, Klumperman J, Jadot M. Cathepsin D and its newly identified transport receptor SEZ6L2 can modulate neurite outgrowth. J Cell Sci. 2016;129:557-68 pubmed publisher
  4. von Einem B, Wahler A, Schips T, Serrano Pozo A, Proepper C, Boeckers T, et al. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1). PLoS ONE. 2015;10:e0129047 pubmed publisher
  5. Dennis M, Mantegazza A, Snir O, Tenza D, Acosta Ruiz A, Delevoye C, et al. BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery. J Cell Biol. 2015;209:563-77 pubmed publisher
  6. Pérez Núñez D, García Urdiales E, Martínez Bonet M, Nogal M, Barroso S, Revilla Y, et al. CD2v Interacts with Adaptor Protein AP-1 during African Swine Fever Infection. PLoS ONE. 2015;10:e0123714 pubmed publisher
  7. Korobko E, Kiselev S, Korobko I. Characterization of Rabaptin-5 γ isoform. Biochemistry (Mosc). 2014;79:856-64 pubmed publisher