This is a Validated Antibody Database (VAD) review about human GDF11, based on 6 published articles (read how Labome selects the articles), using GDF11 antibody in all methods. It is aimed to help Labome visitors find the most suited GDF11 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GDF11 synonym: BMP-11; BMP11; growth/differentiation factor 11; GDF-11; bone morphogenetic protein 11

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (A-1)
  • western blot knockout validation; sheep; fig 4
Santa Cruz Biotechnology GDF11 antibody (Santa Cruz, sc-398333) was used in western blot knockout validation on sheep samples (fig 4). PLoS ONE (2015) ncbi
Abcam
rabbit monoclonal (EPR4567(2))
  • western blot; rat; 1:1000; loading ...; fig 2b
Abcam GDF11 antibody (Abcam, ab124721) was used in western blot on rat samples at 1:1000 (fig 2b). Exp Ther Med (2018) ncbi
rabbit monoclonal (EPR4567(2))
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 5b
Abcam GDF11 antibody (Abcam, ab124721) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 5b). Dev Cell (2017) ncbi
rabbit monoclonal (EPR4567(2))
  • western blot; mouse; loading ...; fig EV2a
Abcam GDF11 antibody (Abcam, ab124721) was used in western blot on mouse samples (fig EV2a). EMBO Mol Med (2017) ncbi
rabbit monoclonal (EPR4567(2))
  • western blot; mouse; loading ...; fig 1c
In order to examine the role of GDF11 in muscle regeneration, Abcam GDF11 antibody (Abcam, ab124721) was used in western blot on mouse samples (fig 1c). Cell Metab (2015) ncbi
R&D Systems
mouse monoclonal (743833)
  • immunohistochemistry; human; 1:200; loading ...; fig s3o
R&D Systems GDF11 antibody (R&D Systems, MAB19581) was used in immunohistochemistry on human samples at 1:200 (fig s3o). Dev Cell (2017) ncbi
mouse monoclonal (743833)
  • western blot; mouse; loading ...; fig 3b
R&D Systems GDF11 antibody (R&D Systems, MAB19581) was used in western blot on mouse samples (fig 3b). EMBO Mol Med (2017) ncbi
mouse monoclonal (743833)
  • western blot; mouse; fig s3
In order to study the role of GDF11 in bone remodeling, R&D Systems GDF11 antibody (R&D, MAB19581) was used in western blot on mouse samples (fig s3). Nat Commun (2016) ncbi
mouse monoclonal (743833)
  • western blot; human; loading ...; fig s2b
In order to examine the role of GDF11 in muscle regeneration, R&D Systems GDF11 antibody (R&D Systems, 743833) was used in western blot on human samples (fig s2b). Cell Metab (2015) ncbi
Abnova
mouse monoclonal (1E6)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 5j
  • western blot; human; 1:500; loading ...; fig s5d
Abnova GDF11 antibody (Novus Biological, H00010220-M03) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 5j) and in western blot on human samples at 1:500 (fig s5d). Dev Cell (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-1)
  • western blot knockout validation; sheep; fig 4
Santa Cruz Biotechnology GDF11 antibody (Santa Cruz, sc-398333) was used in western blot knockout validation on sheep samples (fig 4). PLoS ONE (2015) ncbi
Articles Reviewed
  1. Yang J, Sun L, Fan X, Yin B, Kang Y, Tang L, et al. Effect of exercise on bone in poorly controlled type 1 diabetes mediated by the ActRIIB/Smad signaling pathway. Exp Ther Med. 2018;16:3686-3693 pubmed publisher
  2. Bajikar S, Wang C, Borten M, Pereira E, Atkins K, Janes K. Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer. Dev Cell. 2017;43:418-435.e13 pubmed publisher
  3. Hammers D, Merscham Banda M, Hsiao J, ENGST S, Hartman J, Sweeney H. Supraphysiological levels of GDF11 induce striated muscle atrophy. EMBO Mol Med. 2017;9:531-544 pubmed publisher
  4. Liu W, Zhou L, Zhou C, Zhang S, Jing J, Xie L, et al. GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation. Nat Commun. 2016;7:12794 pubmed publisher
  5. Crispo M, Mulet A, Tesson L, Barrera N, Cuadro F, Dos Santos Neto P, et al. Efficient Generation of Myostatin Knock-Out Sheep Using CRISPR/Cas9 Technology and Microinjection into Zygotes. PLoS ONE. 2015;10:e0136690 pubmed publisher
  6. Egerman M, Cadena S, Gilbert J, Meyer A, Nelson H, Swalley S, et al. GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration. Cell Metab. 2015;22:164-74 pubmed publisher