This is a Validated Antibody Database (VAD) review about human GCLM, based on 9 published articles (read how Labome selects the articles), using GCLM antibody in all methods. It is aimed to help Labome visitors find the most suited GCLM antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GCLM synonym: GLCLR

Abcam
domestic rabbit monoclonal (EPR6667)
  • western blot; human; loading ...; fig 3b
Abcam GCLM antibody (Abcam, ab126704) was used in western blot on human samples (fig 3b). Sci Adv (2022) ncbi
domestic rabbit monoclonal (EPR6667)
  • western blot; mouse; loading ...; fig 3k
Abcam GCLM antibody (Abcam, ab126704) was used in western blot on mouse samples (fig 3k). Adv Sci (Weinh) (2021) ncbi
domestic rabbit monoclonal (EPR6667)
  • western blot; mouse; 1:2000; loading ...; fig 4b
Abcam GCLM antibody (Abcam, ab126704) was used in western blot on mouse samples at 1:2000 (fig 4b). J Nanobiotechnology (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 7a
Abcam GCLM antibody (Abcam, ab153967) was used in western blot on mouse samples at 1:500 (fig 7a). Cell Mol Gastroenterol Hepatol (2021) ncbi
domestic rabbit monoclonal (EPR6667)
  • western blot; human; loading ...; fig 4d
Abcam GCLM antibody (Abcam, ab126704) was used in western blot on human samples (fig 4d). Cancers (Basel) (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 2d
Abcam GCLM antibody (Abcam, ab153967) was used in western blot on mouse samples at 1:500 (fig 2d). Toxicol Appl Pharmacol (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-8)
  • western blot; human; 1:500; fig 5
Santa Cruz Biotechnology GCLM antibody (Santa Cruz, sc166603) was used in western blot on human samples at 1:500 (fig 5). Biochem Pharmacol (2016) ncbi
mouse monoclonal (E-4)
  • western blot; rat
Santa Cruz Biotechnology GCLM antibody (Santa Cruz Biotechnology, sc-55586) was used in western blot on rat samples . Chem Biol Interact (2009) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunocytochemistry; human; fig 6
In order to study the drive of glutathione (GSH) synthesis underlying intrinsic carboplatin resistance of ovarian clear cell carcinoma (OCCC) by HNF1beta, Invitrogen GCLM antibody (Thermo Scientific, PA5-29384) was used in immunocytochemistry on human samples (fig 6). Tumour Biol (2016) ncbi
Articles Reviewed
  1. von M xe4 ssenhausen A, Zamora Gonzalez N, Maremonti F, Belavgeni A, Tonnus W, Meyer C, et al. Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion. Sci Adv. 2022;8:eabl8920 pubmed publisher
  2. Wang P, Yang W, Guo H, Dong H, Guo Y, Gan H, et al. IL-36γ and IL-36Ra Reciprocally Regulate NSCLC Progression by Modulating GSH Homeostasis and Oxidative Stress-Induced Cell Death. Adv Sci (Weinh). 2021;8:e2101501 pubmed publisher
  3. Xiao J, Tu B, Zhou X, Jiang X, Xu G, Zhang J, et al. Autophagy deficiency exacerbates acute lung injury induced by copper oxide nanoparticles. J Nanobiotechnology. 2021;19:162 pubmed publisher
  4. Buitrago Molina L, Marhenke S, Becker D, Geffers R, Itzel T, Teufel A, et al. p53-Independent Induction of p21 Fails to Control Regeneration and Hepatocarcinogenesis in a Murine Liver Injury Model. Cell Mol Gastroenterol Hepatol. 2021;11:1387-1404 pubmed publisher
  5. Qiu L, Wang M, Hu S, Ru X, Ren Y, Zhang Z, et al. Oncogenic Activation of Nrf2, Though as a Master Antioxidant Transcription Factor, Liberated by Specific Knockout of the Full-Length Nrf1α that Acts as a Dominant Tumor Repressor. Cancers (Basel). 2018;10: pubmed publisher
  6. Wang Y, Chen M, Zhang Y, Huo T, Fang Y, Jiao X, et al. Effects of realgar on GSH synthesis in the mouse hippocampus: Involvement of system XAG(-), system XC(-), MRP-1 and Nrf2. Toxicol Appl Pharmacol. 2016;308:91-101 pubmed publisher
  7. Koyani C, Kitz K, Rossmann C, Bernhart E, Huber E, Trummer C, et al. Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death. Biochem Pharmacol. 2016;104:29-41 pubmed publisher
  8. Lopes Coelho F, Gouveia Fernandes S, Gonçalves L, Nunes C, Faustino I, Silva F, et al. HNF1β drives glutathione (GSH) synthesis underlying intrinsic carboplatin resistance of ovarian clear cell carcinoma (OCCC). Tumour Biol. 2016;37:4813-29 pubmed publisher
  9. Paonessa J, Munday C, Mhawech Fauceglia P, Munday R, Zhang Y. 5,6-Dihydrocyclopenta[c][1,2]-dithiole-3(4H)-thione is a promising cancer chemopreventive agent in the urinary bladder. Chem Biol Interact. 2009;180:119-26 pubmed publisher