This is a Validated Antibody Database (VAD) review about human GATA-4, based on 40 published articles (read how Labome selects the articles), using GATA-4 antibody in all methods. It is aimed to help Labome visitors find the most suited GATA-4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GATA-4 synonym: ASD2; TACHD; TOF; VSD1

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (G-4)
  • immunohistochemistry knockout validation; mouse; 1:100; fig 1
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 1
  • chromatin immunoprecipitation; mouse
In order to study the roles of GATA4 and GATA6 in mouse pancreas organogenesis, Santa Cruz Biotechnology GATA-4 antibody (Santa, Sc-25310) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig 1), in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1) and in chromatin immunoprecipitation on mouse samples . J Clin Invest (2012) ncbi
Santa Cruz Biotechnology
mouse monoclonal (G-4)
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, sc-25310) was used . Science (2020) ncbi
mouse monoclonal (G-4)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6b
  • western blot; mouse; loading ...; fig 6a
  • western blot; rat; loading ...; fig 1c
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, G-4) was used in immunohistochemistry - paraffin section on mouse samples (fig 6b), in western blot on mouse samples (fig 6a) and in western blot on rat samples (fig 1c). Cell Death Dis (2019) ncbi
mouse monoclonal (G-4)
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 3d
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, sc-25310) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 3d). Asian J Androl (2020) ncbi
mouse monoclonal (G-4)
  • immunohistochemistry; mouse; 1:50; loading ...; fig 3c
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, SC-25310) was used in immunohistochemistry on mouse samples at 1:50 (fig 3c). Stem Cell Res Ther (2018) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; mouse; fig 7f
Santa Cruz Biotechnology GATA-4 antibody (SantaCruz, sc-25310) was used in immunocytochemistry on mouse samples (fig 7f). Cell (2018) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; mouse; loading ...; fig 1a
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz Biotechnology Inc, sc-25310) was used in immunocytochemistry on mouse samples (fig 1a). Mol Med Rep (2018) ncbi
mouse monoclonal (G-4)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 4
Santa Cruz Biotechnology GATA-4 antibody (SantaCruz, sc-25310) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 4). Oncotarget (2017) ncbi
mouse monoclonal (G-4)
  • western blot; rat; fig 3c
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, sc-25310) was used in western blot on rat samples (fig 3c). Am J Transl Res (2016) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; human; fig 5c
In order to examine the influence of xeno-free expansion media on biological properties of umbilical cord mesenchymal stem cells and their extracellular vesicles, Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz Biotechnology, G-4) was used in immunocytochemistry on human samples (fig 5c). J Mol Med (Berl) (2017) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; human; 1:100; fig 2
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, sc-25310) was used in immunocytochemistry on human samples at 1:100 (fig 2). Sci Rep (2016) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; human; 1:50; fig 1A
In order to develop strategies to assess and characterize sporadic cases of Alzheimer's disease, Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, sc-25310) was used in immunocytochemistry on human samples at 1:50 (fig 1A). Stem Cell Res (2016) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; human; 1:50; fig 1A
In order to develop methods to study and characterize sporadic cases of Alzheimer's disease, Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, sc-25310) was used in immunocytochemistry on human samples at 1:50 (fig 1A). Stem Cell Res (2016) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; human; 1:50; fig 1A
In order to present methods to characterize cells from sporadic cases of Alzheimer's disease, Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, sc-25310) was used in immunocytochemistry on human samples at 1:50 (fig 1A). Stem Cell Res (2016) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; human; 1:50; fig 1A
In order to present a technique to study sporadic cases of Alzheimer's disease, Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, sc-25310) was used in immunocytochemistry on human samples at 1:50 (fig 1A). Stem Cell Res (2016) ncbi
mouse monoclonal (G-4)
  • immunohistochemistry; rat; 1:50; fig 2b
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, sc-25310) was used in immunohistochemistry on rat samples at 1:50 (fig 2b). Sci Rep (2016) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; 1:1000; fig s3
In order to determine regulation of pancreatic endoderm identity through inhibition of hedgehog signaling by GATA4 and GATA6, Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, SC-25310) was used in western blot on mouse samples at 1:1000 (fig s3). Development (2016) ncbi
mouse monoclonal (G-4)
  • immunohistochemistry; mouse; fig 1c
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, 25310) was used in immunohistochemistry on mouse samples (fig 1c). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; human; fig 4
Santa Cruz Biotechnology GATA-4 antibody (santa Cruz, SC-25310) was used in immunocytochemistry on human samples (fig 4). Stem Cell Reports (2015) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; mouse; 1:100
In order to study how Wnt/beta-catenin regulates embryonic stem cell fate, Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, G4) was used in immunocytochemistry on mouse samples at 1:100. Stem Cell Reports (2015) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; mouse
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, SC-25310) was used in immunocytochemistry on mouse samples . Cell Res (2015) ncbi
mouse monoclonal (G-4)
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 3
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz Biotechnology, sc-25310) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 3). Cell Death Dis (2015) ncbi
mouse monoclonal (G-4)
  • immunohistochemistry - paraffin section; mouse
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz Biotechnology, sc-25310) was used in immunohistochemistry - paraffin section on mouse samples . PLoS Genet (2015) ncbi
mouse monoclonal (G-4)
  • western blot; rat; 1:1000
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, sc-25310) was used in western blot on rat samples at 1:1000. Cell Death Dis (2014) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; mouse; 1:200
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, 25310) was used in immunocytochemistry on mouse samples at 1:200. Cell Reprogram (2014) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; 1:200
In order to investigate the mechanisms by which disruption of the Gata4 and Tbx5 interaction in the myocardium contributes to cardiac septation defects, Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, sc-25310) was used in western blot on mouse samples at 1:200. Hum Mol Genet (2014) ncbi
mouse monoclonal (G-4)
  • immunoprecipitation; rat
Santa Cruz Biotechnology GATA-4 antibody (Santa, sc-25310) was used in immunoprecipitation on rat samples . J Biol Chem (2014) ncbi
mouse monoclonal (G-4)
  • immunohistochemistry; bovine
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz Biotechnology, sc-25310) was used in immunohistochemistry on bovine samples . Vet Microbiol (2014) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; human; 1:200
Santa Cruz Biotechnology GATA-4 antibody (Santa Cruz, SC-25310) was used in immunocytochemistry on human samples at 1:200. Stem Cell Rev (2013) ncbi
mouse monoclonal (G-4)
  • immunohistochemistry knockout validation; mouse; 1:100; fig 1
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 1
  • chromatin immunoprecipitation; mouse
In order to study the roles of GATA4 and GATA6 in mouse pancreas organogenesis, Santa Cruz Biotechnology GATA-4 antibody (Santa, Sc-25310) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig 1), in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1) and in chromatin immunoprecipitation on mouse samples . J Clin Invest (2012) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; fig 5c
Santa Cruz Biotechnology GATA-4 antibody (Santa, sc-25310) was used in western blot on mouse samples (fig 5c). J Clin Invest (2011) ncbi
Abcam
domestic rabbit polyclonal
  • immunocytochemistry; rat; 1:500; loading ...; fig 5a
Abcam GATA-4 antibody (ABCAM, ab84593) was used in immunocytochemistry on rat samples at 1:500 (fig 5a). Aging (Albany NY) (2019) ncbi
domestic rabbit monoclonal (EPR4768)
  • western blot; human; loading ...; fig s1h, s1i
Abcam GATA-4 antibody (Epitomics, ab134057) was used in western blot on human samples (fig s1h, s1i). Nat Commun (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 1g
In order to research the damaging effect of Zika virus on rodent testes, Abcam GATA-4 antibody (Abcam, ab84593) was used in immunohistochemistry on mouse samples (fig 1g). Nature (2016) ncbi
domestic rabbit monoclonal (EPR4768)
  • flow cytometry; mouse; fig 5b
In order to show that macrophages that phagocytose dead mesenchymal stem cells encourage changes in the phenotype and growth factor expression, enhanced proliferation, differentiation, and anti-hypoxic activity of cardiac stem cells, Abcam GATA-4 antibody (Abcam, ab134057) was used in flow cytometry on mouse samples (fig 5b). Int J Mol Sci (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; loading ...; fig 7
In order to study the effects of smoking on the cardiac differentiation of mouse embryonic stem cells, Abcam GATA-4 antibody (Abcam, AB84593) was used in immunocytochemistry on mouse samples (fig 7). Toxicology (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 3
Abcam GATA-4 antibody (Abcam, ab84593) was used in western blot on human samples (fig 3). Oncotarget (2016) ncbi
R&D Systems
mouse monoclonal (532020)
  • immunohistochemistry; common marmoset; fig 2
R&D Systems GATA-4 antibody (R&D Systems, MAB2606) was used in immunohistochemistry on common marmoset samples (fig 2). Hepat Med (2020) ncbi
mouse monoclonal (532020)
  • immunocytochemistry; mouse; fig 1b
  • immunocytochemistry; human; fig s1a
  • western blot; human; fig s1b
R&D Systems GATA-4 antibody (R&D, MAB2606) was used in immunocytochemistry on mouse samples (fig 1b), in immunocytochemistry on human samples (fig s1a) and in western blot on human samples (fig s1b). PLoS ONE (2015) ncbi
Invitrogen
rat monoclonal (eBioEvan)
  • immunocytochemistry; mouse; 1:400; loading ...; fig 1a
In order to investigate the gene expression dynamics of early mouse embryonic stem cell differentiation, Invitrogen GATA-4 antibody (eBiosciences, 14-9980) was used in immunocytochemistry on mouse samples at 1:400 (fig 1a). elife (2017) ncbi
rat monoclonal (eBioEvan)
  • immunocytochemistry; human; 1:200; fig 2
In order to assess the effect of tobacco smoke on CDK14 expression, Invitrogen GATA-4 antibody (Affymetrix eBioscience, 14-9980-80) was used in immunocytochemistry on human samples at 1:200 (fig 2). Toxicol Lett (2015) ncbi
Articles Reviewed
  1. Weber C, Zhou Y, Lee J, Looger L, Qian G, Ge C, et al. Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b. Science. 2020;368:303-306 pubmed publisher
  2. Aravalli R, COLLINS D, Hapke J, Crane A, Steer C. Hepatic Differentiation of Marmoset Embryonic Stem Cells and Functional Characterization of ESC-Derived Hepatocyte-Like Cells. Hepat Med. 2020;12:15-27 pubmed publisher
  3. Qi L, Chi X, Zhang X, Feng X, Chu W, Zhang S, et al. Kindlin-2 suppresses transcription factor GATA4 through interaction with SUV39H1 to attenuate hypertrophy. Cell Death Dis. 2019;10:890 pubmed publisher
  4. Moreno Blas D, Gorostieta Salas E, Pommer Alba A, Muciño Hernández G, Gerónimo Olvera C, Maciel Barón L, et al. Cortical neurons develop a senescence-like phenotype promoted by dysfunctional autophagy. Aging (Albany NY). 2019;11:6175-6198 pubmed publisher
  5. Cao J, Lin Z, Tong M, Zhang Y, Li Y, Zhou Y. Mechanistic target of rapamycin kinase (Mtor) is required for spermatogonial proliferation and differentiation in mice. Asian J Androl. 2020;22:169-176 pubmed publisher
  6. Gao L, Hu Y, Tian Y, Fan Z, Wang K, Li H, et al. Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition. Nat Commun. 2019;10:1665 pubmed publisher
  7. Tu J, Tian G, Cheung H, Wei W, Lee T. Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells. Stem Cell Res Ther. 2018;9:71 pubmed publisher
  8. Han X, Wang R, Zhou Y, Fei L, Sun H, Lai S, et al. Mapping the Mouse Cell Atlas by Microwell-Seq. Cell. 2018;172:1091-1107.e17 pubmed publisher
  9. Tian J, Wang R, Hou Q, Li M, Chen L, Deng X, et al. Optimization and enrichment of induced cardiomyocytes derived from mouse fibroblasts by reprogramming with cardiac transcription factors. Mol Med Rep. 2018;17:3912-3920 pubmed publisher
  10. Ayars M, O Sullivan E, Macgregor Das A, Shindo K, Kim H, Borges M, et al. IL2RG, identified as overexpressed by RNA-seq profiling of pancreatic intraepithelial neoplasia, mediates pancreatic cancer growth. Oncotarget. 2017;8:83370-83383 pubmed publisher
  11. Jang S, Choubey S, Furchtgott L, Zou L, Doyle A, Menon V, et al. Dynamics of embryonic stem cell differentiation inferred from single-cell transcriptomics show a series of transitions through discrete cell states. elife. 2017;6: pubmed publisher
  12. Li F, Li Z, Jiang Z, Tian Y, Wang Z, Yi W, et al. Enhancement of early cardiac differentiation of dedifferentiated fat cells by dimethyloxalylglycine via notch signaling pathway. Am J Transl Res. 2016;8:4791-4801 pubmed
  13. Govero J, Esakky P, Scheaffer S, Fernandez E, Drury A, Platt D, et al. Zika virus infection damages the testes in mice. Nature. 2016;540:438-442 pubmed publisher
  14. Bobis Wozowicz S, Kmiotek K, Kania K, Karnas E, Labedz Maslowska A, Sekula M, et al. Diverse impact of xeno-free conditions on biological and regenerative properties of hUC-MSCs and their extracellular vesicles. J Mol Med (Berl). 2017;95:205-220 pubmed publisher
  15. Pettinato G, Ramanathan R, Fisher R, Mangino M, Zhang N, Wen X. Scalable Differentiation of Human iPSCs in a Multicellular Spheroid-based 3D Culture into Hepatocyte-like Cells through Direct Wnt/?-catenin Pathway Inhibition. Sci Rep. 2016;6:32888 pubmed publisher
  16. Tancos Z, Varga E, Kovacs E, Dinnyes A, Kobolak J. Establishment of induced pluripotent stem cell (iPSC) line from a 75-year old patient with late onset Alzheimer's disease (LOAD). Stem Cell Res. 2016;17:81-83 pubmed publisher
  17. Chandrasekaran A, Varga E, Nemes C, Tancos Z, Kobolak J, Dinnyes A. Establishment of induced pluripotent stem cell (iPSC) line from a 63-year old patient with late onset Alzheimer's disease (LOAD). Stem Cell Res. 2016;17:78-80 pubmed publisher
  18. Tancos Z, Varga E, Kovacs E, Dinnyes A, Kobolak J. Establishment of induced pluripotent stem cell (iPSC) line from an 84-year old patient with late onset Alzheimer's disease (LOAD). Stem Cell Res. 2016;17:75-77 pubmed publisher
  19. Ochalek A, Nemes C, Varga E, Tancos Z, Kobolak J, Dinnyes A. Establishment of induced pluripotent stem cell (iPSC) line from a 57-year old patient with sporadic Alzheimer's disease. Stem Cell Res. 2016;17:72-74 pubmed publisher
  20. Liu L, Jin X, Zhou Z, Shen C. Enhancement of Anti-Hypoxic Activity and Differentiation of Cardiac Stem Cells by Supernatant Fluids from Cultured Macrophages that Phagocytized Dead Mesenchymal Stem Cells. Int J Mol Sci. 2016;17: pubmed publisher
  21. Cheng W, Zhou R, Feng Y, Wang Y. Mainstream smoke and sidestream smoke affect the cardiac differentiation of mouse embryonic stem cells discriminately. Toxicology. 2016;357-358:1-10 pubmed publisher
  22. Isotani A, Yamagata K, Okabe M, Ikawa M. Generation of Hprt-disrupted rat through mouse?rat ES chimeras. Sci Rep. 2016;6:24215 pubmed publisher
  23. Xuan S, Sussel L. GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling. Development. 2016;143:780-6 pubmed publisher
  24. Cano E, Carmona R, Ruiz Villalba A, Rojas A, Chau Y, Wagner K, et al. Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections. Proc Natl Acad Sci U S A. 2016;113:656-61 pubmed publisher
  25. Wu S, Yang Z, Ye R, An D, Li C, Wang Y, et al. Novel variants in MLL confer to bladder cancer recurrence identified by whole-exome sequencing. Oncotarget. 2016;7:2629-45 pubmed publisher
  26. Agu C, Soares F, Alderton A, Patel M, Ansari R, Patel S, et al. Successful Generation of Human Induced Pluripotent Stem Cell Lines from Blood Samples Held at Room Temperature for up to 48 hr. Stem Cell Reports. 2015;5:660-71 pubmed publisher
  27. Qiu D, Ye S, Ruiz B, Zhou X, Liu D, Zhang Q, et al. Klf2 and Tfcp2l1, Two Wnt/β-Catenin Targets, Act Synergistically to Induce and Maintain Naive Pluripotency. Stem Cell Reports. 2015;5:314-22 pubmed publisher
  28. Fu Y, Huang C, Xu X, Gu H, Ye Y, Jiang C, et al. Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails. Cell Res. 2015;25:1013-24 pubmed publisher
  29. Xu J, Wan P, Wang M, Zhang J, Gao X, Hu B, et al. AIP1-mediated actin disassembly is required for postnatal germ cell migration and spermatogonial stem cell niche establishment. Cell Death Dis. 2015;6:e1818 pubmed publisher
  30. Belian E, Noseda M, Abreu Paiva M, Leja T, Sampson R, Schneider M. Forward Programming of Cardiac Stem Cells by Homogeneous Transduction with MYOCD plus TBX5. PLoS ONE. 2015;10:e0125384 pubmed publisher
  31. Hu Y, Nicholls P, Soh Y, Daniele J, Junker J, van Oudenaarden A, et al. Licensing of primordial germ cells for gametogenesis depends on genital ridge signaling. PLoS Genet. 2015;11:e1005019 pubmed publisher
  32. Pollack D, Xiao Y, Shrivasatava V, Levy A, Andrusier M, D ARMIENTO J, et al. CDK14 expression is down-regulated by cigarette smoke in vivo and in vitro. Toxicol Lett. 2015;234:120-30 pubmed publisher
  33. Aries A, Whitcomb J, Shao W, Komati H, Saleh M, Nemer M. Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate. Cell Death Dis. 2014;5:e1566 pubmed publisher
  34. Ma M, Czepiel M, Krause T, Schafer K, Boddeke E, Copray S. Generation of induced pluripotent stem cells from hair follicle bulge neural crest stem cells. Cell Reprogram. 2014;16:307-13 pubmed publisher
  35. Misra C, Chang S, Basu M, Huang N, Garg V. Disruption of myocardial Gata4 and Tbx5 results in defects in cardiomyocyte proliferation and atrioventricular septation. Hum Mol Genet. 2014;23:5025-35 pubmed publisher
  36. Reineke E, Benham A, Soibam B, Stashi E, Taegtmeyer H, Entman M, et al. Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function. J Biol Chem. 2014;289:17721-31 pubmed publisher
  37. Newcomer B, Toohey Kurth K, Zhang Y, Brodersen B, Marley M, Joiner K, et al. Laboratory diagnosis and transmissibility of bovine viral diarrhea virus from a bull with a persistent testicular infection. Vet Microbiol. 2014;170:246-57 pubmed publisher
  38. Delli Carri A, Onorati M, Castiglioni V, Faedo A, Camnasio S, Toselli M, et al. Human pluripotent stem cell differentiation into authentic striatal projection neurons. Stem Cell Rev. 2013;9:461-74 pubmed publisher
  39. Carrasco M, Delgado I, Soria B, Martin F, Rojas A. GATA4 and GATA6 control mouse pancreas organogenesis. J Clin Invest. 2012;122:3504-15 pubmed publisher
  40. Yang Y, Ahn Y, Gibbons D, Zang Y, Lin W, Thilaganathan N, et al. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J Clin Invest. 2011;121:1373-85 pubmed publisher