This is a Validated Antibody Database (VAD) review about human GATA-2, based on 15 published articles (read how Labome selects the articles), using GATA-2 antibody in all methods. It is aimed to help Labome visitors find the most suited GATA-2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GATA-2 synonym: DCML; IMD21; MONOMAC; NFE1B; endothelial transcription factor GATA-2

Abcam
rabbit monoclonal (EPR2822(2))
  • western blot; mouse; loading ...; fig 2b
Abcam GATA-2 antibody (Abcam, ab109241) was used in western blot on mouse samples (fig 2b). elife (2018) ncbi
rabbit monoclonal (EPR2822(2))
  • western blot; mouse; 1:1000; loading ...; fig 5a
  • western blot; human; 1:1000; loading ...; fig 9a
In order to study the involvement of SENP1-mediated GATA2 deSUMOylation in graft arteriosclerosis, Abcam GATA-2 antibody (Abcam, ab109241) was used in western blot on mouse samples at 1:1000 (fig 5a) and in western blot on human samples at 1:1000 (fig 9a). Nat Commun (2017) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:100; loading ...; fig 1d
In order to study the involvement of SENP1-mediated GATA2 deSUMOylation in graft arteriosclerosis, Abcam GATA-2 antibody (Abcam, ab173817) was used in immunohistochemistry on human samples at 1:100 (fig 1d). Nat Commun (2017) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse; fig 4
  • western blot; mouse; fig 3
Abcam GATA-2 antibody (Abcam, ab22849) was used in chromatin immunoprecipitation on mouse samples (fig 4) and in western blot on mouse samples (fig 3). Autophagy (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Abcam GATA-2 antibody (Abcam, ab22849) was used in western blot on mouse samples . J Biol Chem (2015) ncbi
rabbit monoclonal (EPR2822(2))
  • immunoprecipitation; human
In order to demonstrate that Fbw7 is an E3 ubiquitin ligase for GATA2 in vivo, Abcam GATA-2 antibody (Abcam, ab109241) was used in immunoprecipitation on human samples . J Biol Chem (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (CG2-96)
  • western blot; mouse; 1:500; loading ...; fig 6b
In order to research the role of microRNA miR-34a in pluripotent stem cells, Santa Cruz Biotechnology GATA-2 antibody (Santa Cruz, CG2-96) was used in western blot on mouse samples at 1:500 (fig 6b). Science (2017) ncbi
mouse monoclonal (CG2-96)
  • ChIP-Seq; mouse; fig 1
Santa Cruz Biotechnology GATA-2 antibody (Santa Cruz, sc267) was used in ChIP-Seq on mouse samples (fig 1). Dev Cell (2016) ncbi
mouse monoclonal (CG2-96)
  • western blot; mouse; fig 5c
Santa Cruz Biotechnology GATA-2 antibody (Santa, sc-267) was used in western blot on mouse samples (fig 5c). J Clin Invest (2011) ncbi
Abnova
mouse monoclonal (2D11)
  • flow cytometry; human; 1:100; loading ...; fig 2a
Abnova GATA-2 antibody (Abnova, H00002624-M01) was used in flow cytometry on human samples at 1:100 (fig 2a). Genome Biol (2017) ncbi
Invitrogen
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; fig 8
In order to investigate the developmental processes that regulate the formation of unique inner ear cell types, Invitrogen GATA-2 antibody (ThermoFisher Scientific, PA1?C100) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 8). Nat Commun (2015) ncbi
MilliporeSigma
rabbit polyclonal
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, MilliporeSigma GATA-2 antibody (SIGMA, AV31855) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (2D11)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, MilliporeSigma GATA-2 antibody (SIGMA, 2D11) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; fig 1b
Cell Signaling Technology GATA-2 antibody (Cell Signaling, 4595) was used in western blot on human samples (fig 1b). Nat Genet (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4d
In order to show the Nogo-B receptor promotes accumulation of prenylated Ras at the plasma membrane, Cell Signaling Technology GATA-2 antibody (cell signalling, 4595) was used in western blot on human samples (fig 4d). Oncogene (2017) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; fig 2
  • western blot; mouse; fig 2
Cell Signaling Technology GATA-2 antibody (Cell Signaling, 4595) was used in immunohistochemistry on mouse samples (fig 2) and in western blot on mouse samples (fig 2). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology GATA-2 antibody (Cell signaling, 4595S) was used in western blot on human samples (fig 5). Oncogene (2016) ncbi
Articles Reviewed
  1. Bergiers I, Andrews T, Vargel Bölükbaşı Ö, Buness A, Janosz E, Lopez Anguita N, et al. Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis. elife. 2018;7: pubmed publisher
  2. van Groningen T, Koster J, Valentijn L, Zwijnenburg D, Akogul N, Hasselt N, et al. Neuroblastoma is composed of two super-enhancer-associated differentiation states. Nat Genet. 2017;49:1261-1266 pubmed publisher
  3. Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, et al. The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. Nat Commun. 2017;8:15426 pubmed publisher
  4. Litzenburger U, Buenrostro J, Wu B, Shen Y, Sheffield N, Kathiria A, et al. Single-cell epigenomic variability reveals functional cancer heterogeneity. Genome Biol. 2017;18:15 pubmed publisher
  5. Choi Y, Lin C, Risso D, Chen S, Kim T, Tan M, et al. Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells. Science. 2017;355: pubmed publisher
  6. Zhao B, Hu W, Kumar S, Gonyo P, Rana U, Liu Z, et al. The Nogo-B receptor promotes Ras plasma membrane localization and activation. Oncogene. 2017;36:3406-3416 pubmed publisher
  7. Xiao L, Feng Q, Zhang Z, Wang F, Lydon J, Ittmann M, et al. The essential role of GATA transcription factors in adult murine prostate. Oncotarget. 2016;7:47891-47903 pubmed publisher
  8. Goode D, Obier N, Vijayabaskar M, Lie A Ling M, Lilly A, Hannah R, et al. Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation. Dev Cell. 2016;36:572-87 pubmed publisher
  9. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  10. Zhao J, Fong K, Jin H, Yang Y, Kim J, Yu J. FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression. Oncogene. 2016;35:4335-44 pubmed publisher
  11. Burns J, Kelly M, Hoa M, Morell R, Kelley M. Single-cell RNA-Seq resolves cellular complexity in sensory organs from the neonatal inner ear. Nat Commun. 2015;6:8557 pubmed publisher
  12. Yuan J, Zhang Y, Sheng Y, Fu X, Cheng H, Zhou R. MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals. Autophagy. 2015;11:1081-98 pubmed publisher
  13. Majumder A, Syed K, Joseph S, Scambler P, Dutta D. Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1. J Biol Chem. 2015;290:13053-63 pubmed publisher
  14. Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, et al. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2. J Biol Chem. 2015;290:10368-81 pubmed publisher
  15. Yang Y, Ahn Y, Gibbons D, Zang Y, Lin W, Thilaganathan N, et al. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J Clin Invest. 2011;121:1373-85 pubmed publisher