This is a Validated Antibody Database (VAD) review about human GARS, based on 24 published articles (read how Labome selects the articles), using GARS antibody in all methods. It is aimed to help Labome visitors find the most suited GARS antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GARS synonym: CMT2D; DSMAV; GlyRS; HMN5; SMAD1; glycine--tRNA ligase; AP-4-A synthetase; Charcot-Marie-Tooth neuropathy 2D; Charcot-Marie-Tooth neuropathy, neuronal type, D; diadenosine tetraphosphate synthetase

Santa Cruz Biotechnology
mouse monoclonal (D-10)
  • immunoprecipitation; human; loading ...; fig 3c
Santa Cruz Biotechnology GARS antibody (Santa cruz, D-10) was used in immunoprecipitation on human samples (fig 3c). Nat Struct Mol Biol (2016) ncbi
Abnova
mouse polyclonal
  • western blot; human; loading ...; fig 3c
Abnova GARS antibody (Abnova, B01P) was used in western blot on human samples (fig 3c). Nat Struct Mol Biol (2016) ncbi
mouse polyclonal
  • western blot; mouse; 1:1000; fig s5b
In order to elucidate the link between CMT2D neuropathy and glycyl-tRNA synthetase, Abnova GARS antibody (Abnova, H00002617-B01P) was used in western blot on mouse samples at 1:1000 (fig s5b). Nature (2015) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; fruit fly; 1:100
In order to develop a Drosophila model for Charcot-Marie-Tooth by mutating glycyl-tRNA synthetase, Proteintech Group GARS antibody (Proteintech, 15831-1-AP) was used in western blot on fruit fly samples at 1:100. Nat Commun (2015) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; loading ...; fig 2f
Cell Signaling Technology GARS antibody (Cell Signaling, 9743S) was used in western blot on human samples (fig 2f). Nat Commun (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1e
In order to study the oncogenic role of ERK1 in glioma, Cell Signaling Technology GARS antibody (CST, 9743) was used in western blot on human samples (fig 1e). J Immunol (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2d
Cell Signaling Technology GARS antibody (Cell Signaling, 9743S) was used in western blot on mouse samples at 1:1000 (fig 2d). Blood (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 2b
Cell Signaling Technology GARS antibody (Cell Signaling Technology, 9743) was used in western blot on human samples at 1:1000 (fig 2b). Nat Commun (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig s5a
Cell Signaling Technology GARS antibody (Cell Signaling, 9743) was used in western blot on mouse samples (fig s5a). PLoS Genet (2017) ncbi
rabbit polyclonal
  • western blot; mouse; fig 8
Cell Signaling Technology GARS antibody (Cell Signaling, 97435) was used in western blot on mouse samples (fig 8). Exp Cell Res (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:500; fig 6
Cell Signaling Technology GARS antibody (Cell Signaling, 9743) was used in western blot on mouse samples at 1:500 (fig 6). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunoprecipitation; mouse; 1:100; loading ...; fig 8c
  • western blot; mouse; 1:1000; loading ...; fig 7c
In order to investigate the contribution of YAP in mouse neocortical astrocytic differentiation and proliferation, Cell Signaling Technology GARS antibody (Cell Signaling, 9743) was used in immunoprecipitation on mouse samples at 1:100 (fig 8c) and in western blot on mouse samples at 1:1000 (fig 7c). Development (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; chicken; 1:100; fig 1
  • western blot; chicken; 1:100; fig 2
In order to determine regulation of neural tube closure by modulating tight junctions by cell-cycle-dependent TGFbeta-BMP antagonism, Cell Signaling Technology GARS antibody (Cell signaling, 9743S) was used in immunohistochemistry on chicken samples at 1:100 (fig 1) and in western blot on chicken samples at 1:100 (fig 2). J Cell Sci (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 5
Cell Signaling Technology GARS antibody (cell Signaling Tech, 9743s) was used in western blot on human samples at 1:1000 (fig 5). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig s1
Cell Signaling Technology GARS antibody (Cell Signaling, 9743S) was used in western blot on human samples at 1:1000 (fig s1). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 5
Cell Signaling Technology GARS antibody (Cell signaling, 9743) was used in western blot on human samples at 1:1000 (fig 5). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 6
Cell Signaling Technology GARS antibody (Cell Signaling, 9743) was used in western blot on human samples at 1:1000 (fig 6). Am J Physiol Gastrointest Liver Physiol (2015) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3b
Cell Signaling Technology GARS antibody (Cell Signaling Technology, 9743) was used in western blot on mouse samples (fig 3b). J Mol Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology GARS antibody (Cell Signalling, 9743) was used in western blot on mouse samples . Stem Cells (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology GARS antibody (Cell Signaling, 9743) was used in western blot on mouse samples . Biochim Biophys Acta (2015) ncbi
rabbit polyclonal
  • western blot; rat; 1:500
Cell Signaling Technology GARS antibody (Cell Signaling, 9743) was used in western blot on rat samples at 1:500. Biochim Biophys Acta (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology GARS antibody (Cell Signaling Technology , 9743) was used in western blot on human samples (fig 1). FASEB J (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology GARS antibody (Cell Signal, 9743) was used in western blot on human samples at 1:1000. Stem Cells Dev (2014) ncbi
rabbit polyclonal
  • western blot; mouse
In order to study the role of endothelial-to-mesenchymal transition in the onset and progression of cerebral cavernous malformations, Cell Signaling Technology GARS antibody (Cell Signaling, 9743) was used in western blot on mouse samples . Nature (2013) ncbi
BD Biosciences
rat monoclonal (N6-1233)
  • western blot; human; 1:1000; fig 7c
In order to evaluate the ability of Chrdl1 to suppress bone morphogenetic protein-induced increases in breast cancer cell migration and invasion, BD Biosciences GARS antibody (BD Biosciences, 562508) was used in western blot on human samples at 1:1000 (fig 7c). Mol Cell Biol (2016) ncbi
Articles Reviewed
  1. Dufton N, Peghaire C, Osuna Almagro L, Raimondi C, Kalna V, Chuahan A, et al. Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis. Nat Commun. 2017;8:895 pubmed publisher
  2. Ventura E, Weller M, Burghardt I. Cutting Edge: ERK1 Mediates the Autocrine Positive Feedback Loop of TGF-? and Furin in Glioma-Initiating Cells. J Immunol. 2017;198:4569-4574 pubmed publisher
  3. Wang C, Core A, Canali S, Zumbrennen Bullough K, Ozer S, Umans L, et al. Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice. Blood. 2017;130:73-83 pubmed publisher
  4. Hurst L, Dunmore B, Long L, Crosby A, Al Lamki R, Deighton J, et al. TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling. Nat Commun. 2017;8:14079 pubmed publisher
  5. Jiang C, Diao F, Sang Y, Xu N, Zhu R, Wang X, et al. GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. PLoS Genet. 2017;13:e1006535 pubmed publisher
  6. Zhao G, Zhu P, Renvoisé B, Maldonado Baez L, Park S, Blackstone C. Mammalian knock out cells reveal prominent roles for atlastin GTPases in ER network morphology. Exp Cell Res. 2016;349:32-44 pubmed publisher
  7. Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, et al. Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nat Commun. 2016;7:12503 pubmed publisher
  8. Huang Z, Hu J, Pan J, Wang Y, Hu G, Zhou J, et al. YAP stabilizes SMAD1 and promotes BMP2-induced neocortical astrocytic differentiation. Development. 2016;143:2398-409 pubmed publisher
  9. Mo Z, Zhang Q, Liu Z, Lauer J, Shi Y, Sun L, et al. Neddylation requires glycyl-tRNA synthetase to protect activated E2. Nat Struct Mol Biol. 2016;23:730-7 pubmed publisher
  10. Amarnath S, Agarwala S. Cell-cycle-dependent TGF?-BMP antagonism regulates neural tube closure by modulating tight junctions. J Cell Sci. 2017;130:119-131 pubmed publisher
  11. Cyr Depauw C, Northey J, Tabariès S, Annis M, Dong Z, Cory S, et al. Chordin-Like 1 Suppresses Bone Morphogenetic Protein 4-Induced Breast Cancer Cell Migration and Invasion. Mol Cell Biol. 2016;36:1509-25 pubmed publisher
  12. He W, Bai G, Zhou H, Wei N, White N, Lauer J, et al. CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase. Nature. 2015;526:710-4 pubmed publisher
  13. Huan C, Yang T, Liang J, Xie T, Cheng L, Liu N, et al. Methylation-mediated BMPER expression in fibroblast activation in vitro and lung fibrosis in mice in vivo. Sci Rep. 2015;5:14910 pubmed publisher
  14. Niehues S, Bussmann J, Steffes G, Erdmann I, Köhrer C, Sun L, et al. Impaired protein translation in Drosophila models for Charcot-Marie-Tooth neuropathy caused by mutant tRNA synthetases. Nat Commun. 2015;6:7520 pubmed publisher
  15. Krishnan S, Szabo E, Burghardt I, Frei K, Tabatabai G, Weller M. Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition. Oncotarget. 2015;6:22480-95 pubmed
  16. Aspalter I, Gordon E, Dubrac A, Ragab A, Narloch J, Vizan P, et al. Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch. Nat Commun. 2015;6:7264 pubmed publisher
  17. Alkhateeb A, Buckett P, Gardeck A, Kim J, Byrne S, Fraenkel P, et al. The small molecule ferristatin II induces hepatic hepcidin expression in vivo and in vitro. Am J Physiol Gastrointest Liver Physiol. 2015;308:G1019-26 pubmed publisher
  18. Ruan X, Zuo Q, Jia H, Chau J, Lin J, Ao J, et al. P53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers. J Mol Cell Biol. 2015;7:105-18 pubmed publisher
  19. Galvagni F, Lentucci C, Neri F, Dettori D, De Clemente C, Orlandini M, et al. Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes. Stem Cells. 2015;33:742-50 pubmed publisher
  20. Kim J, Shim M. Prostaglandin F2α receptor (FP) signaling regulates Bmp signaling and promotes chondrocyte differentiation. Biochim Biophys Acta. 2015;1853:500-12 pubmed publisher
  21. Borkham Kamphorst E, Schaffrath C, Van De Leur E, Haas U, Tihaa L, Meurer S, et al. The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-? signaling. Biochim Biophys Acta. 2014;1843:902-14 pubmed publisher
  22. Holtzhausen A, Golzio C, How T, Lee Y, Schiemann W, Katsanis N, et al. Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development. FASEB J. 2014;28:1248-67 pubmed publisher
  23. Feng N, Han Q, Li J, Wang S, Li H, Yao X, et al. Generation of highly purified neural stem cells from human adipose-derived mesenchymal stem cells by Sox1 activation. Stem Cells Dev. 2014;23:515-29 pubmed publisher
  24. Maddaluno L, Rudini N, Cuttano R, Bravi L, Giampietro C, Corada M, et al. EndMT contributes to the onset and progression of cerebral cavernous malformations. Nature. 2013;498:492-6 pubmed publisher