This is a Validated Antibody Database (VAD) review about human GALC, based on 28 published articles (read how Labome selects the articles), using GALC antibody in all methods. It is aimed to help Labome visitors find the most suited GALC antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GALC synonym: galactocerebrosidase; GALCERase; galactocerebroside beta-galactosidase; galactosylceramide beta-galactosidase; galactosylceraminidase; testis tissue sperm-binding protein Li 88E; testis tissue sperm-binding protein Li 89A

EMD Millipore
mouse monoclonal (mGalc)
  • immunohistochemistry - frozen section; human; loading ...; fig 5a
EMD Millipore GALC antibody (Sigma-Aldrich, MAB342) was used in immunohistochemistry - frozen section on human samples (fig 5a). J Lipid Res (2018) ncbi
mouse monoclonal (mGalc)
  • immunocytochemistry; rat; loading ...; fig s2c
In order to probe the role of mTOR-dependent signaling among neuronal and nonneuronal cells in myelin regulation, EMD Millipore GALC antibody (EMD Millipore, MAB342) was used in immunocytochemistry on rat samples (fig s2c). J Exp Med (2017) ncbi
mouse monoclonal (mGalc)
  • immunohistochemistry - frozen section; rat; 1:100; loading ...; fig 7
In order to investigate 2-methylcitrate-induced brain toxicity, EMD Millipore GALC antibody (Millipore, MAB342) was used in immunohistochemistry - frozen section on rat samples at 1:100 (fig 7). Mol Genet Metab (2016) ncbi
mouse monoclonal (mGalc)
  • immunohistochemistry - free floating section; human; fig 2
In order to characterize nuclear indentations that are tau-positive in P301S tauopathy mice, EMD Millipore GALC antibody (Chemicon, MAB342) was used in immunohistochemistry - free floating section on human samples (fig 2). Brain Pathol (2017) ncbi
mouse monoclonal (mGalc)
  • immunohistochemistry - frozen section; mouse; 1:500; fig s13a
In order to study neocrotical development and promotion of astrocytogenesis by Zbtb20, EMD Millipore GALC antibody (Millipore, MAB342) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig s13a). Nat Commun (2016) ncbi
mouse monoclonal (mGalc)
  • flow cytometry; human; fig 4
EMD Millipore GALC antibody (Millipore, MAB342A4) was used in flow cytometry on human samples (fig 4). Int J Oncol (2015) ncbi
mouse monoclonal (mGalc)
  • immunocytochemistry; rat; 1:50
EMD Millipore GALC antibody (EMD Millipore, MAB342) was used in immunocytochemistry on rat samples at 1:50. Mol Med Rep (2015) ncbi
mouse monoclonal (mGalc)
  • immunocytochemistry; rat; 1:500
EMD Millipore GALC antibody (Millipore, MAB342) was used in immunocytochemistry on rat samples at 1:500. J Neurosci (2015) ncbi
mouse monoclonal (mGalc)
  • other; mouse; fig 5
EMD Millipore GALC antibody (Millipore, MAB342) was used in other on mouse samples (fig 5). Nat Commun (2015) ncbi
mouse monoclonal (mGalc)
  • immunocytochemistry; mouse; fig 7
EMD Millipore GALC antibody (EMD Millipore, MAB342) was used in immunocytochemistry on mouse samples (fig 7). Nat Commun (2014) ncbi
mouse monoclonal (mGalc)
  • immunocytochemistry; human; 1:200
In order to evaluate a co-culture system for studying the neurovascular unit, EMD Millipore GALC antibody (Millipore, MAB342) was used in immunocytochemistry on human samples at 1:200. PLoS ONE (2014) ncbi
mouse monoclonal (mGalc)
  • immunocytochemistry; mouse; 1:200
EMD Millipore GALC antibody (Millipore, MAB342) was used in immunocytochemistry on mouse samples at 1:200. Glia (2014) ncbi
mouse monoclonal (mGalc)
  • flow cytometry; human
EMD Millipore GALC antibody (Millipore, MAB342A4) was used in flow cytometry on human samples . J Comp Neurol (2014) ncbi
mouse monoclonal (mGalc)
  • immunohistochemistry; mouse; 1:1000
In order to confirm the role of PTEN signaling in Olig2 expressing neural progenitor cells and oligodendrocytes, EMD Millipore GALC antibody (Milipore, MAB342) was used in immunohistochemistry on mouse samples at 1:1000. Stem Cells (2014) ncbi
mouse monoclonal (mGalc)
  • immunohistochemistry - free floating section; rat; 1:200
In order to study the alpha-synuclein transfers from neurons to oligodendrocytes, EMD Millipore GALC antibody (Millipore, MAB342A4) was used in immunohistochemistry - free floating section on rat samples at 1:200. Glia (2014) ncbi
mouse monoclonal (mGalc)
  • immunocytochemistry; human; 1:200
EMD Millipore GALC antibody (Millipore, MAB342) was used in immunocytochemistry on human samples at 1:200. Neuro Oncol (2014) ncbi
mouse monoclonal (mGalc)
  • immunocytochemistry; mouse
EMD Millipore GALC antibody (Millipore, MAB342) was used in immunocytochemistry on mouse samples . Anal Chem (2013) ncbi
mouse monoclonal (mGalc)
  • immunohistochemistry; mouse; 1:250
EMD Millipore GALC antibody (Millipore, MAB342) was used in immunohistochemistry on mouse samples at 1:250. Stem Cells Dev (2014) ncbi
mouse monoclonal (mGalc)
  • immunocytochemistry; mouse; 1:300
EMD Millipore GALC antibody (Chemicon, MAB342) was used in immunocytochemistry on mouse samples at 1:300. Methods Mol Biol (2013) ncbi
mouse monoclonal (mGalc)
  • western blot; human; 1:2000
In order to investigate the effect of valproate in the activation of FGF1 gene promoter, EMD Millipore GALC antibody (EMD Millipore, MAB342) was used in western blot on human samples at 1:2000. J Neurochem (2013) ncbi
mouse monoclonal (mGalc)
  • immunocytochemistry; rat
EMD Millipore GALC antibody (Chemicon, MAB342) was used in immunocytochemistry on rat samples . Exp Neurol (2013) ncbi
mouse monoclonal (mGalc)
  • immunocytochemistry; Burton's mouthbrooder; 1:100
In order to evaluate a culture system for astroglial cells derived from brain of adult cichlid fish, EMD Millipore GALC antibody (Millipore, Mab342) was used in immunocytochemistry on Burton's mouthbrooder samples at 1:100. J Neurosci Methods (2013) ncbi
mouse monoclonal (mGalc)
  • chromatin immunoprecipitation; human
EMD Millipore GALC antibody (EMD Millipore, MAB342) was used in chromatin immunoprecipitation on human samples . J Neurosci Res (2013) ncbi
mouse monoclonal (mGalc)
  • immunohistochemistry; rat; 1:500
In order to evaluate integration-deficient lentiviral vectors for gene transfer in the spinal cord, EMD Millipore GALC antibody (Millipore, MAB342) was used in immunohistochemistry on rat samples at 1:500. Gene Ther (2013) ncbi
mouse monoclonal (mGalc)
  • immunohistochemistry - frozen section; mouse; 1:200
In order to study the self-renewal and differentiation of reactive astrocyte-derived neural stem/progenitor cells isolated after stroke, EMD Millipore GALC antibody (Millipore, MAB342) was used in immunohistochemistry - frozen section on mouse samples at 1:200. J Neurosci (2012) ncbi
mouse monoclonal (mGalc)
  • immunohistochemistry - free floating section; mouse; 1:200
EMD Millipore GALC antibody (Millipore, MAB342) was used in immunohistochemistry - free floating section on mouse samples at 1:200. J Comp Neurol (2011) ncbi
mouse monoclonal (mGalc)
  • immunocytochemistry; mouse; 1:200
EMD Millipore GALC antibody (Chemicon, MAB342) was used in immunocytochemistry on mouse samples at 1:200. J Comp Neurol (2009) ncbi
Sigma-Aldrich
rabbit polyclonal
  • immunocytochemistry; mouse; 1:200; loading ...; fig 2c
Sigma-Aldrich GALC antibody (Sigma, G9152) was used in immunocytochemistry on mouse samples at 1:200 (fig 2c). Neurochem Res (2018) ncbi
Articles Reviewed
  1. Allende M, Cook E, Larman B, Nugent A, Brady J, Golebiowski D, et al. Cerebral organoids derived from Sandhoff disease-induced pluripotent stem cells exhibit impaired neurodifferentiation. J Lipid Res. 2018;59:550-563 pubmed publisher
  2. Jana M, Ghosh S, Pahan K. Upregulation of Myelin Gene Expression by a Physically-Modified Saline via Phosphatidylinositol 3-Kinase-Mediated Activation of CREB: Implications for Multiple Sclerosis. Neurochem Res. 2018;43:407-419 pubmed publisher
  3. Ercan E, Han J, Di Nardo A, Winden K, Han M, Hoyo L, et al. Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex. J Exp Med. 2017;214:681-697 pubmed publisher
  4. Cudré Cung H, Zavadakova P, Do Vale Pereira S, Remacle N, Henry H, Ivanisevic J, et al. Ammonium accumulation is a primary effect of 2-methylcitrate exposure in an in vitro model for brain damage in methylmalonic aciduria. Mol Genet Metab. 2016;119:57-67 pubmed publisher
  5. Fernández Nogales M, Santos Galindo M, Merchán Rubira J, Hoozemans J, Rábano A, Ferrer I, et al. Tau-positive nuclear indentations in P301S tauopathy mice. Brain Pathol. 2017;27:314-322 pubmed publisher
  6. Nagao M, Ogata T, Sawada Y, Gotoh Y. Zbtb20 promotes astrocytogenesis during neocortical development. Nat Commun. 2016;7:11102 pubmed publisher
  7. Yamamuro S, Sano E, Okamoto Y, Ochiai Y, Ohta T, Ogino A, et al. Antitumorigenic effect of interferon-β by inhibition of undifferentiated glioblastoma cells. Int J Oncol. 2015;47:1647-54 pubmed publisher
  8. Liu R, Wang Z, Gou L, Xu H. A cortical astrocyte subpopulation inhibits axon growth in vitro and in vivo. Mol Med Rep. 2015;12:2598-606 pubmed publisher
  9. Göttle P, Sabo J, Heinen A, Venables G, Torres K, Tzekova N, et al. Oligodendroglial maturation is dependent on intracellular protein shuttling. J Neurosci. 2015;35:906-19 pubmed publisher
  10. Giera S, Deng Y, Luo R, Ackerman S, Mogha A, Monk K, et al. The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development. Nat Commun. 2015;6:6121 pubmed publisher
  11. Pooya S, Liu X, Kumar V, Anderson J, Imai F, Zhang W, et al. The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism. Nat Commun. 2014;5:4993 pubmed publisher
  12. Chou C, Sinden J, Couraud P, Modo M. In vitro modeling of the neurovascular environment by coculturing adult human brain endothelial cells with human neural stem cells. PLoS ONE. 2014;9:e106346 pubmed publisher
  13. Chucair Elliott A, Conrady C, Zheng M, Kroll C, Lane T, Carr D. Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells. Glia. 2014;62:1418-34 pubmed publisher
  14. Nguyen H, Nekanti U, Haus D, Funes G, Moreno D, Kamei N, et al. Induction of early neural precursors and derivation of tripotent neural stem cells from human pluripotent stem cells under xeno-free conditions. J Comp Neurol. 2014;522:2767-83 pubmed publisher
  15. Maire C, Ramkissoon S, Hayashi M, Haidar S, Ramkissoon L, diTomaso E, et al. Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy. Stem Cells. 2014;32:313-26 pubmed publisher
  16. Reyes J, Rey N, Bousset L, Melki R, Brundin P, Angot E. Alpha-synuclein transfers from neurons to oligodendrocytes. Glia. 2014;62:387-98 pubmed publisher
  17. Wolpert F, Tritschler I, Steinle A, Weller M, Eisele G. A disintegrin and metalloproteinases 10 and 17 modulate the immunogenicity of glioblastoma-initiating cells. Neuro Oncol. 2014;16:382-91 pubmed publisher
  18. Lin C, Lee D, Chang H, Chiu I, Hsu C. Single-cell enzyme-free dissociation of neurospheres using a microfluidic chip. Anal Chem. 2013;85:11920-8 pubmed publisher
  19. Momcilovic O, Liu Q, Swistowski A, Russo Tait T, Zhao Y, Rao M, et al. Genome wide profiling of dopaminergic neurons derived from human embryonic and induced pluripotent stem cells. Stem Cells Dev. 2014;23:406-20 pubmed publisher
  20. Azari H. Isolation and enrichment of defined neural cell populations from heterogeneous neural stem cell progeny. Methods Mol Biol. 2013;1059:95-106 pubmed publisher
  21. Kao C, Hsu Y, Liu J, Lee D, Chung Y, Chiu I. The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities. J Neurochem. 2013;126:4-18 pubmed publisher
  22. Pendleton J, Shamblott M, Gary D, Belegu V, Hurtado A, Malone M, et al. Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTP?. Exp Neurol. 2013;247:113-21 pubmed publisher
  23. Mack A, Tiedemann K. Cultures of astroglial cells derived from brain of adult cichlid fish. J Neurosci Methods. 2013;212:269-75 pubmed publisher
  24. Darbinyan A, Kaminski R, White M, Darbinian Sarkissian N, Khalili K. Polyomavirus JC infection inhibits differentiation of oligodendrocyte progenitor cells. J Neurosci Res. 2013;91:116-27 pubmed publisher
  25. Peluffo H, Foster E, Ahmed S, Lago N, Hutson T, Moon L, et al. Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord. Gene Ther. 2013;20:645-57 pubmed publisher
  26. Shimada I, LeComte M, Granger J, Quinlan N, Spees J. Self-renewal and differentiation of reactive astrocyte-derived neural stem/progenitor cells isolated from the cortical peri-infarct area after stroke. J Neurosci. 2012;32:7926-40 pubmed publisher
  27. Bøttger P, Tracz Z, Heuck A, Nissen P, Romero Ramos M, Lykke Hartmann K. Distribution of Na/K-ATPase alpha 3 isoform, a sodium-potassium P-type pump associated with rapid-onset of dystonia parkinsonism (RDP) in the adult mouse brain. J Comp Neurol. 2011;519:376-404 pubmed publisher
  28. Gritti A, Dal Molin M, Foroni C, Bonfanti L. Effects of developmental age, brain region, and time in culture on long-term proliferation and multipotency of neural stem cell populations. J Comp Neurol. 2009;517:333-49 pubmed publisher