This is a Validated Antibody Database (VAD) review about human G substrate, based on 38 published articles (read how Labome selects the articles), using G substrate antibody in all methods. It is aimed to help Labome visitors find the most suited G substrate antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
G substrate synonym: C7orf16; GSBS

Cell Signaling Technology
domestic rabbit monoclonal (100G7E)
  • western blot; mouse; 1:1000; fig 2e, 6b
Cell Signaling Technology G substrate antibody (Cell Signaling, 9624S) was used in western blot on mouse samples at 1:1000 (fig 2e, 6b). elife (2022) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; mouse; 1:500; loading ...; fig 6d
Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in western blot on mouse samples at 1:500 (fig 6d). elife (2021) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology G substrate antibody (Cell Signaling Technology, 9624) was used in western blot on human samples (fig 3b). Cell Death Differ (2021) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; mouse; 1:10,000; loading ...; fig s4-1a
Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in western blot on mouse samples at 1:10,000 (fig s4-1a). elife (2021) ncbi
domestic rabbit monoclonal (100G7E)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig s2a
Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in immunohistochemistry on mouse samples at 1:1000 (fig s2a). Cell Rep (2021) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; mouse; 1:1000; loading ...; fig 1d
Cell Signaling Technology G substrate antibody (Cell Signaling Technology, 100G7E) was used in western blot on mouse samples at 1:1000 (fig 1d). elife (2020) ncbi
domestic rabbit monoclonal (D23H2/D69H5)
  • western blot; mouse; loading ...; fig 6c
  • western blot; human; loading ...; fig 1d
Cell Signaling Technology G substrate antibody (Cell Signaling, 9607) was used in western blot on mouse samples (fig 6c) and in western blot on human samples (fig 1d). Cancers (Basel) (2019) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; rat; 1:1000; loading ...; fig 5b
Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in western blot on rat samples at 1:1000 (fig 5b). Aging Cell (2020) ncbi
domestic rabbit monoclonal (D23H2/D69H5)
  • western blot; human; 1:1000; loading ...; fig 1a
Cell Signaling Technology G substrate antibody (Cell Signaling Technology, 9607) was used in western blot on human samples at 1:1000 (fig 1a). Cancer Discov (2019) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in western blot on human samples (fig 2c). Sci Adv (2019) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human; 1:1000; loading ...; fig 5a
Cell Signaling Technology G substrate antibody (Cell signaling, 9624) was used in western blot on human samples at 1:1000 (fig 5a). elife (2019) ncbi
domestic rabbit monoclonal (D23H2/D69H5)
  • western blot; human; 1:1000; loading ...; fig s4b
Cell Signaling Technology G substrate antibody (Cell Signaling, 9607) was used in western blot on human samples at 1:1000 (fig s4b). Sci Adv (2019) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human; 1:1000; loading ...; fig 1s1b
Cell Signaling Technology G substrate antibody (Cell signaling, 9624) was used in western blot on human samples at 1:1000 (fig 1s1b). elife (2019) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; mouse; 1:1000; loading ...; fig 5b
Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in western blot on mouse samples at 1:1000 (fig 5b). Nat Commun (2019) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human; loading ...; fig 4g
Cell Signaling Technology G substrate antibody (CST, 9624) was used in western blot on human samples (fig 4g). EMBO J (2019) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; mouse; 1:1000; loading ...; fig st2
Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in western blot on mouse samples at 1:1000 (fig st2). Gastroenterology (2017) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human; 1:1000; loading ...; fig 2c
Cell Signaling Technology G substrate antibody (Cell Signaling, 100G7E) was used in western blot on human samples at 1:1000 (fig 2c). Science (2017) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human; loading ...; fig 6c
Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in western blot on human samples (fig 6c). Oncotarget (2017) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human; loading ...; tbl 4
Cell Signaling Technology G substrate antibody (Cell signaling, 9624) was used in western blot on human samples (tbl 4). Transl Psychiatry (2016) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human; loading ...; fig 3b
In order to study phosphorylation of p12, Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in western blot on human samples (fig 3b). J Virol (2016) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human
In order to describe the effects of long- and short-term exposure to erythropoietin on white adipose tissue, Cell Signaling Technology G substrate antibody (Cell signaling, 9624) was used in western blot on human samples . Lipids Health Dis (2016) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human; loading ...; fig 4g
In order to analyze pro- and anti-lipolytic signaling pathways in adipocytes after in vivo endotoxin exposure, Cell Signaling Technology G substrate antibody (Cell signaling, 9624) was used in western blot on human samples (fig 4g). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; mouse; loading ...; fig s2b
Cell Signaling Technology G substrate antibody (CST, 9624) was used in western blot on mouse samples (fig s2b). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D9V5N)
  • western blot; human; 1:1000; fig 9
Cell Signaling Technology G substrate antibody (Cell Signaling Tech, 14371) was used in western blot on human samples at 1:1000 (fig 9). Nat Commun (2016) ncbi
domestic rabbit monoclonal (100G7E)
In order to describe a signaling pathway from beta-adrenergic receptor and protein kinase A via mTORC1 that is required for adipose browning by catecholamines, Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used . J Clin Invest (2016) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology G substrate antibody (Cell Signaling Technologies, 9624) was used in western blot on mouse samples at 1:1000 (fig 6). Nat Commun (2016) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human; fig 4
Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in western blot on human samples (fig 4). Mol Endocrinol (2016) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; rat; 1:2000; loading ...; fig s3a
In order to report the effects of manganese exposure on the developing dopaminergic system in the striatum of rats, Cell Signaling Technology G substrate antibody (Cell signalling, 9624) was used in western blot on rat samples at 1:2000 (fig s3a). Metallomics (2016) ncbi
domestic rabbit monoclonal (100G7E)
  • chromatin immunoprecipitation; African green monkey
Cell Signaling Technology G substrate antibody (Cell Signaling Technology, 9624) was used in chromatin immunoprecipitation on African green monkey samples . J Cell Sci (2016) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; human; 1:1000; fig 1
Cell Signaling Technology G substrate antibody (Cell Signaling Tech, 9624S) was used in western blot on human samples at 1:1000 (fig 1). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; mouse; 1:1000; fig 4
Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in western blot on mouse samples at 1:1000 (fig 4). Nat Cell Biol (2015) ncbi
domestic rabbit monoclonal (100G7E)
Cell Signaling Technology G substrate antibody (Cell Signaling Technology, 9624) was used . PLoS ONE (2015) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; mouse; 1:1000
In order to investigate serotonin signaling in adipose tissue, Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in western blot on mouse samples at 1:1000. Nat Med (2015) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; mouse; fig 1,2,3,4,5,6
In order to determine the role of progesterone receptor activation in increasing protein turnover and downregulation of GATA3 transcriptional repression which promotes breast tumor growth, Cell Signaling Technology G substrate antibody (cell signaling, 100G7E) was used in western blot on mouse samples (fig 1,2,3,4,5,6). Breast Cancer Res (2014) ncbi
domestic rabbit monoclonal (D23H2/D69H5)
  • western blot; rat
Cell Signaling Technology G substrate antibody (Cell Signaling Technology, 9607) was used in western blot on rat samples . Life Sci (2015) ncbi
domestic rabbit monoclonal (D23H2/D69H5)
  • western blot; human; 1:1000; fig 7d
In order to show that the zinc finger E-box binding homeobox 1 regulates radiosensitivity and the DNA damage response in breast cancer cells, Cell Signaling Technology G substrate antibody (Cell Signaling Technology,, 9607) was used in western blot on human samples at 1:1000 (fig 7d). Nat Cell Biol (2014) ncbi
domestic rabbit monoclonal (100G7E)
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse
Cell Signaling Technology G substrate antibody (Cell Signaling Technology, 9624) was used in immunohistochemistry - paraffin section on mouse samples and in western blot on mouse samples . PLoS ONE (2012) ncbi
domestic rabbit monoclonal (100G7E)
  • western blot; mouse
Cell Signaling Technology G substrate antibody (Cell Signaling, 9624) was used in western blot on mouse samples . Nature (2012) ncbi
Articles Reviewed
  1. Patritti Cram J, Wu J, Coover R, Rizvi T, Chaney K, Ravindran R, et al. P2RY14 cAMP signaling regulates Schwann cell precursor self-renewal, proliferation, and nerve tumor initiation in a mouse model of neurofibromatosis. elife. 2022;11: pubmed publisher
  2. Reynoso S, Castillo V, Katkar G, López Sánchez I, Taheri S, Espinoza C, et al. GIV/Girdin, a non-receptor modulator for Gαi/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility. elife. 2021;10: pubmed publisher
  3. Grisan F, Iannucci L, Surdo N, Gerbino A, Zanin S, Di Benedetto G, et al. PKA compartmentalization links cAMP signaling and autophagy. Cell Death Differ. 2021;28:2436-2449 pubmed publisher
  4. Wang F, Gervasi M, Boskovic A, Sun F, Rinaldi V, Yu J, et al. Deficient spermiogenesis in mice lacking Rlim. elife. 2021;10: pubmed publisher
  5. Schlein C, Fischer A, Sass F, Worthmann A, Tödter K, Jaeckstein M, et al. Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution. Cell Rep. 2021;34:108624 pubmed publisher
  6. Chen C, Soto G, Dumrongprechachan V, BANNON N, Kang S, Kozorovitskiy Y, et al. Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations. elife. 2020;9: pubmed publisher
  7. Song Y, Lu H, Wang Q, Xiang R. Targeting Angiogenesis by Blocking the ATM-SerRS-VEGFA Pathway for UV-Induced Skin Photodamage and Melanoma Growth. Cancers (Basel). 2019;11: pubmed publisher
  8. Ye J, Yin Y, Liu H, Fang L, Tao X, Wei L, et al. Tau inhibits PKA by nuclear proteasome-dependent PKAR2α elevation with suppressed CREB/GluA1 phosphorylation. Aging Cell. 2020;19:e13055 pubmed publisher
  9. Zhang J, Lee Y, Dang F, Gan W, Menon A, Katon J, et al. PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discov. 2019;: pubmed publisher
  10. Sun Y, Liu Z, Cao X, Lu Y, Mi Z, He C, et al. Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease. Sci Adv. 2019;5:eaaw3593 pubmed publisher
  11. Jewell J, Fu V, Hong A, Yu F, Meng D, Melick C, et al. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. elife. 2019;8: pubmed publisher
  12. Sonego M, Pellarin I, Costa A, Vinciguerra G, Coan M, Kraut A, et al. USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability. Sci Adv. 2019;5:eaav3235 pubmed publisher
  13. Turnham R, Smith F, Kenerson H, Omar M, Golkowski M, Garcia I, et al. An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma. elife. 2019;8: pubmed publisher
  14. Araiz C, Yan A, Bettedi L, Samuelson I, Virtue S, McGavigan A, et al. Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissue. Nat Commun. 2019;10:1546 pubmed publisher
  15. Gioran A, Piazzesi A, Bertan F, Schroer J, Wischhof L, Nicotera P, et al. Multi-omics identify xanthine as a pro-survival metabolite for nematodes with mitochondrial dysfunction. EMBO J. 2019;38: pubmed publisher
  16. Sundaresan S, Meininger C, Kang A, Photenhauer A, Hayes M, Sahoo N, et al. Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells. Gastroenterology. 2017;153:1555-1567.e15 pubmed publisher
  17. Smith F, Esseltine J, Nygren P, Veesler D, Byrne D, Vonderach M, et al. Local protein kinase A action proceeds through intact holoenzymes. Science. 2017;356:1288-1293 pubmed publisher
  18. Li G, Fu R, Shen H, Zhou J, Hu X, Liu Y, et al. Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Oncotarget. 2017;8:10359-10374 pubmed publisher
  19. Lopes M, Leal R, Guarnieri R, Schwarzbold M, Hoeller A, Diaz A, et al. A single high dose of dexamethasone affects the phosphorylation state of glutamate AMPA receptors in the human limbic system. Transl Psychiatry. 2016;6:e986 pubmed publisher
  20. Brzezinski J, Felkner R, Modi A, Liu M, Roth M. Phosphorylation Requirement of Murine Leukemia Virus p12. J Virol. 2016;90:11208-11219 pubmed
  21. Christensen B, Nellemann B, Jørgensen J, Pedersen S, Jessen N. Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo. Lipids Health Dis. 2016;15:160 pubmed publisher
  22. Rittig N, Bach E, Thomsen H, Pedersen S, Nielsen T, Jørgensen J, et al. Regulation of Lipolysis and Adipose Tissue Signaling during Acute Endotoxin-Induced Inflammation: A Human Randomized Crossover Trial. PLoS ONE. 2016;11:e0162167 pubmed publisher
  23. Gallardo Montejano V, Saxena G, Kusminski C, Yang C, McAfee J, Hahner L, et al. Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1?/SIRT1-dependent transcriptional regulation of mitochondrial function. Nat Commun. 2016;7:12723 pubmed publisher
  24. Rasmussen M, Lyskjær I, Jersie Christensen R, Tarpgaard L, Primdal Bengtson B, Nielsen M, et al. miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells. Nat Commun. 2016;7:12436 pubmed publisher
  25. Liu D, Bordicchia M, Zhang C, Fang H, Wei W, Li J, et al. Activation of mTORC1 is essential for ?-adrenergic stimulation of adipose browning. J Clin Invest. 2016;126:1704-16 pubmed publisher
  26. Johanns M, Lai Y, Hsu M, Jacobs R, Vertommen D, Van Sande J, et al. AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B. Nat Commun. 2016;7:10856 pubmed publisher
  27. Kaya Okur H, Das A, Taylor R, Bagchi I, Bagchi M. Roles of Estrogen Receptor-α and the Coactivator MED1 During Human Endometrial Decidualization. Mol Endocrinol. 2016;30:302-13 pubmed publisher
  28. Peres T, Ong L, Costa A, Eyng H, Venske D, Colle D, et al. Tyrosine hydroxylase regulation in adult rat striatum following short-term neonatal exposure to manganese. Metallomics. 2016;8:597-604 pubmed publisher
  29. Kilisch M, Lytovchenko O, Arakel E, Bertinetti D, Schwappach B. A dual phosphorylation switch controls 14-3-3-dependent cell surface expression of TASK-1. J Cell Sci. 2016;129:831-42 pubmed publisher
  30. Liu K, Frazier W. Phosphorylation of the BNIP3 C-Terminus Inhibits Mitochondrial Damage and Cell Death without Blocking Autophagy. PLoS ONE. 2015;10:e0129667 pubmed publisher
  31. Iglesias Bartolomé R, Torres D, Marone R, Feng X, Martin D, Simaan M, et al. Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015;17:793-803 pubmed publisher
  32. Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, et al. Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. PLoS ONE. 2015;10:e0119415 pubmed publisher
  33. Crane J, Palanivel R, Mottillo E, Bujak A, Wang H, Ford R, et al. Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis. Nat Med. 2015;21:166-72 pubmed publisher
  34. Izzo F, Mercogliano F, Venturutti L, Tkach M, Inurrigarro G, Schillaci R, et al. Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth. Breast Cancer Res. 2014;16:491 pubmed publisher
  35. Liu H, Xie Q, Xin B, Liu J, Liu Y, Li Y, et al. Inhibition of autophagy recovers cardiac dysfunction and atrophy in response to tail-suspension. Life Sci. 2015;121:1-9 pubmed publisher
  36. Zhang P, Wei Y, Wang L, Debeb B, Yuan Y, Zhang J, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol. 2014;16:864-75 pubmed publisher
  37. Martin S, Fernandez Rojo M, Stanley A, Bastiani M, Okano S, Nixon S, et al. Caveolin-1 deficiency leads to increased susceptibility to cell death and fibrosis in white adipose tissue: characterization of a lipodystrophic model. PLoS ONE. 2012;7:e46242 pubmed publisher
  38. Wang Y, Li G, Goode J, Paz J, Ouyang K, Screaton R, et al. Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature. 2012;485:128-32 pubmed publisher