This is a Validated Antibody Database (VAD) review about human FOXC1, based on 9 published articles (read how Labome selects the articles), using FOXC1 antibody in all methods. It is aimed to help Labome visitors find the most suited FOXC1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FOXC1 synonym: ARA; ASGD3; FKHL7; FREAC-3; FREAC3; IGDA; IHG1; IRID1; RIEG3

Knockout validation
Abcam
domestic rabbit monoclonal (EPR20685)
  • western blot knockout validation; human; loading ...; fig 2a
  • immunohistochemistry; human; loading ...; fig 1b
Abcam FOXC1 antibody (Abcam, ab227977) was used in western blot knockout validation on human samples (fig 2a) and in immunohistochemistry on human samples (fig 1b). Front Cell Dev Biol (2021) ncbi
Abcam
domestic rabbit monoclonal (EPR20685)
  • western blot knockout validation; human; loading ...; fig 2a
  • immunohistochemistry; human; loading ...; fig 1b
Abcam FOXC1 antibody (Abcam, ab227977) was used in western blot knockout validation on human samples (fig 2a) and in immunohistochemistry on human samples (fig 1b). Front Cell Dev Biol (2021) ncbi
domestic rabbit monoclonal (EPR20678)
  • immunohistochemistry; human; 1:500; fig 3f
Abcam FOXC1 antibody (Abcam, ab223850) was used in immunohistochemistry on human samples at 1:500 (fig 3f). Nat Commun (2021) ncbi
domestic rabbit monoclonal (EPR20685)
  • immunocytochemistry; human; 1:400; fig 5e
Abcam FOXC1 antibody (Abcam, ab227977) was used in immunocytochemistry on human samples at 1:400 (fig 5e). Cells (2021) ncbi
domestic rabbit monoclonal (EPR20685)
  • immunohistochemistry - paraffin section; human; 1:400; loading ...; fig 4a
  • chromatin immunoprecipitation; human; loading ...; fig 2i
  • western blot; human; 1:1000; loading ...; fig 2f
Abcam FOXC1 antibody (Abcam, ab227977) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 4a), in chromatin immunoprecipitation on human samples (fig 2i) and in western blot on human samples at 1:1000 (fig 2f). J Exp Clin Cancer Res (2021) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 5a
Invitrogen FOXC1 antibody (Thermo Fisher Scientific, PA1-807) was used in western blot on human samples at 1:500 (fig 5a). Mol Ther Nucleic Acids (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D8A6)
  • western blot; human; 1:1000; loading ...; fig s6a
Cell Signaling Technology FOXC1 antibody (Cell Signaling Technology, 8758s) was used in western blot on human samples at 1:1000 (fig s6a). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D8A6)
  • immunohistochemistry; mouse; loading ...; fig 1
Cell Signaling Technology FOXC1 antibody (Cell Signaling, 8758S) was used in immunohistochemistry on mouse samples (fig 1). elife (2020) ncbi
domestic rabbit monoclonal (D8A6)
  • western blot; human; fig s10f
Cell Signaling Technology FOXC1 antibody (Cell Signaling, 8758) was used in western blot on human samples (fig s10f). Nat Genet (2019) ncbi
domestic rabbit monoclonal (D8A6)
  • immunohistochemistry; mouse
Cell Signaling Technology FOXC1 antibody (Cell Signaling, D8A6) was used in immunohistochemistry on mouse samples . Science (2016) ncbi
domestic rabbit monoclonal (D8A6)
  • western blot; human; 1:1000; fig 1B
Cell Signaling Technology FOXC1 antibody (Cell Signaling Technology, 8758) was used in western blot on human samples at 1:1000 (fig 1B). Mol Med Rep (2015) ncbi
Articles Reviewed
  1. Ouyang X, Feng L, Yao L, Xiao Y, Hu X, Zhang G, et al. Testicular orphan receptor 4 (TR4) promotes papillary thyroid cancer invasion via activating circ-FNLA/miR-149-5p/MMP9 signaling. Mol Ther Nucleic Acids. 2021;24:755-767 pubmed publisher
  2. Jiang J, Li J, Yao W, Wang W, Shi B, Yuan F, et al. FOXC1 Negatively Regulates DKK1 Expression to Promote Gastric Cancer Cell Proliferation Through Activation of Wnt Signaling Pathway. Front Cell Dev Biol. 2021;9:662624 pubmed publisher
  3. Huang H, Hu J, Maryam A, Huang Q, Zhang Y, Ramakrishnan S, et al. Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling. Nat Commun. 2021;12:2242 pubmed publisher
  4. Grönroos P, Ilmarinen T, Skottman H. Directed Differentiation of Human Pluripotent Stem Cells towards Corneal Endothelial-Like Cells under Defined Conditions. Cells. 2021;10: pubmed publisher
  5. Lin Z, Huang W, He Q, Li D, Wang Z, Feng Y, et al. FOXC1 promotes HCC proliferation and metastasis by Upregulating DNMT3B to induce DNA Hypermethylation of CTH promoter. J Exp Clin Cancer Res. 2021;40:50 pubmed publisher
  6. Norden P, Sabine A, Wang Y, Demir C, Liu T, Petrova T, et al. Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation. elife. 2020;9: pubmed publisher
  7. Assi S, Imperato M, Coleman D, Pickin A, Potluri S, Ptasinska A, et al. Subtype-specific regulatory network rewiring in acute myeloid leukemia. Nat Genet. 2019;51:151-162 pubmed publisher
  8. Wang L, Siegenthaler J, Dowell R, Yi R. Foxc1 reinforces quiescence in self-renewing hair follicle stem cells. Science. 2016;351:613-7 pubmed publisher
  9. Ou Yang L, Xiao S, Liu P, Yi S, Zhang X, Ou Yang S, et al. Forkhead box C1 induces epithelial‑mesenchymal transition and is a potential therapeutic target in nasopharyngeal carcinoma. Mol Med Rep. 2015;12:8003-9 pubmed publisher