This is a Validated Antibody Database (VAD) review about human FOXA2, based on 34 published articles (read how Labome selects the articles), using FOXA2 antibody in all methods. It is aimed to help Labome visitors find the most suited FOXA2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FOXA2 synonym: HNF3B; TCF3B

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D56D6)
  • western blot knockout validation; human; fig 6b
In order to identify transcription factors involved in pancreatic ductal adenocarcinoma pathogenesis, Cell Signaling Technology FOXA2 antibody (Cell Signaling, 8189) was used in western blot knockout validation on human samples (fig 6b). Am J Physiol Gastrointest Liver Physiol (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR4466)
  • immunohistochemistry; mouse; 1:1000; fig 3e
Abcam FOXA2 antibody (Abcam, ab108422) was used in immunohistochemistry on mouse samples at 1:1000 (fig 3e). Cell Rep Methods (2022) ncbi
domestic rabbit monoclonal (EPR4466)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 2a
Abcam FOXA2 antibody (Abcam, ab108422) was used in immunohistochemistry on mouse samples at 1:1000 (fig 2a). Nat Commun (2021) ncbi
domestic rabbit monoclonal (EPR4466)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 4e
Abcam FOXA2 antibody (Abcam, ab108422) was used in immunohistochemistry on mouse samples at 1:1000 (fig 4e). Genes Dev (2021) ncbi
domestic rabbit monoclonal (EPR4466)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 4a
Abcam FOXA2 antibody (Abcam, ab108422) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 4a). Sci Rep (2021) ncbi
mouse monoclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 1e
Abcam FOXA2 antibody (Abcam, ab60721) was used in immunohistochemistry - paraffin section on human samples (fig 1e). Stem Cell Reports (2020) ncbi
domestic rabbit monoclonal (EPR4466)
  • western blot; mouse; loading ...; fig 3c
Abcam FOXA2 antibody (Abcam, ab108422) was used in western blot on mouse samples (fig 3c). Acta Naturae (2019) ncbi
mouse monoclonal
  • western blot; human; 1:1000; loading ...; fig 4f
Abcam FOXA2 antibody (abcam, ab60721) was used in western blot on human samples at 1:1000 (fig 4f). Biosci Rep (2019) ncbi
domestic rabbit monoclonal (EPR4466)
  • western blot; human; 1:1000; loading ...; fig 6d
Abcam FOXA2 antibody (Abcam, ab108422) was used in western blot on human samples at 1:1000 (fig 6d). Stem Cells (2019) ncbi
mouse monoclonal
  • immunocytochemistry; mouse; fig s2c
In order to identify and characterize extended pluripotent stem cells, Abcam FOXA2 antibody (Abcam, ab60721) was used in immunocytochemistry on mouse samples (fig s2c). Cell (2017) ncbi
mouse monoclonal
  • immunocytochemistry; human; 5 ug/ml; fig 2
Abcam FOXA2 antibody (Abcam, ab60721) was used in immunocytochemistry on human samples at 5 ug/ml (fig 2). Sci Rep (2016) ncbi
domestic rabbit monoclonal (EPR4466)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 7d
Abcam FOXA2 antibody (Abcam, AB108422) was used in immunohistochemistry - paraffin section on mouse samples (fig 7d). Sci Rep (2016) ncbi
mouse monoclonal
  • western blot; human; 1:200; fig 1d
Abcam FOXA2 antibody (Abcam, ab60721) was used in western blot on human samples at 1:200 (fig 1d). Nat Commun (2015) ncbi
domestic rabbit monoclonal (EPR4466)
  • immunohistochemistry - paraffin section; mouse; 1:250
In order to study the role of TGFBR1 for mouse myometrial development, Abcam FOXA2 antibody (Abcam, ab108422) was used in immunohistochemistry - paraffin section on mouse samples at 1:250. Mol Endocrinol (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-4)
  • immunocytochemistry; human; 1:50; loading ...; fig 1g
Santa Cruz Biotechnology FOXA2 antibody (SantaCruz, sc374376) was used in immunocytochemistry on human samples at 1:50 (fig 1g). Stem Cell Res (2018) ncbi
mouse monoclonal (RY-7)
  • immunocytochemistry; human; 1:100; fig 6
Santa Cruz Biotechnology FOXA2 antibody (Santa Cruz, sc-101060) was used in immunocytochemistry on human samples at 1:100 (fig 6). Sci Rep (2016) ncbi
mouse monoclonal (RY-7)
  • immunocytochemistry; human; fig 6
Santa Cruz Biotechnology FOXA2 antibody (Santa Cruz, sc-101060) was used in immunocytochemistry on human samples (fig 6). Nat Commun (2016) ncbi
mouse monoclonal (H-8)
  • immunocytochemistry; human; 1:200; fig 2
Santa Cruz Biotechnology FOXA2 antibody (Santa Cruz, sc-271104) was used in immunocytochemistry on human samples at 1:200 (fig 2). Nat Commun (2016) ncbi
Abnova
mouse monoclonal (7.00E+06)
  • immunohistochemistry - frozen section; human; 1:500; loading ...; fig 7e
Abnova FOXA2 antibody (Novus, H00003170-M01) was used in immunohistochemistry - frozen section on human samples at 1:500 (fig 7e). Nature (2019) ncbi
mouse monoclonal (7.00E+06)
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 1g
In order to use naked mole-rat-induced pluripotent stem cells to study mechanisms of cancer resistance, Abnova FOXA2 antibody (ABNOVA, 7E6) was used in immunocytochemistry on mouse samples at 1:1000 (fig 1g). Nat Commun (2016) ncbi
BioLegend
mouse monoclonal (P87H4B7)
  • immunocytochemistry; human; 1:100; loading ...; fig 4d
  • western blot; human; loading ...; fig 4c
BioLegend FOXA2 antibody (BioLegend, 685802) was used in immunocytochemistry on human samples at 1:100 (fig 4d) and in western blot on human samples (fig 4c). Sci Adv (2020) ncbi
Novus Biologicals
mouse monoclonal (OTI3C10)
  • western blot; mouse; loading ...; fig 4o
Novus Biologicals FOXA2 antibody (Novus, NBP2-02088) was used in western blot on mouse samples (fig 4o). Dev Biol (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D56D6)
Cell Signaling Technology FOXA2 antibody (Cell signalling, 8186) was used . Nat Cell Biol (2021) ncbi
domestic rabbit monoclonal (D56D6)
  • immunohistochemistry; mouse; 1:200; loading ...; fig e10d
Cell Signaling Technology FOXA2 antibody (Cell Signalling Technologies, D56D6) was used in immunohistochemistry on mouse samples at 1:200 (fig e10d). Nature (2020) ncbi
domestic rabbit monoclonal (D56D6)
  • immunocytochemistry; human; loading ...; fig s1d
Cell Signaling Technology FOXA2 antibody (Cell Signaling, 8186S) was used in immunocytochemistry on human samples (fig s1d). Nucleic Acids Res (2020) ncbi
domestic rabbit monoclonal (D56D6)
  • immunohistochemistry; mouse; fig 2b
Cell Signaling Technology FOXA2 antibody (CST, 8186) was used in immunohistochemistry on mouse samples (fig 2b). Dev Cell (2019) ncbi
domestic rabbit monoclonal (D56D6)
  • immunohistochemistry - paraffin section; mouse; 1:250; loading ...; fig 4s1b
Cell Signaling Technology FOXA2 antibody (CST, D56D6) was used in immunohistochemistry - paraffin section on mouse samples at 1:250 (fig 4s1b). elife (2019) ncbi
domestic rabbit monoclonal (D56D6)
  • immunohistochemistry; mouse; loading ...; fig s6c
Cell Signaling Technology FOXA2 antibody (Cell Signaling, 8186) was used in immunohistochemistry on mouse samples (fig s6c). Nature (2019) ncbi
domestic rabbit monoclonal (D56D6)
  • immunocytochemistry; human; fig s1d
Cell Signaling Technology FOXA2 antibody (Cell Signaling, 8186P) was used in immunocytochemistry on human samples (fig s1d). Cell (2018) ncbi
domestic rabbit monoclonal (D56D6)
  • immunocytochemistry; mouse; 1:400; loading ...; fig 1a
In order to investigate the gene expression dynamics of early mouse embryonic stem cell differentiation, Cell Signaling Technology FOXA2 antibody (Cell Signaling, 8186) was used in immunocytochemistry on mouse samples at 1:400 (fig 1a). elife (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; fig 6
Cell Signaling Technology FOXA2 antibody (Cell Signaling, 3143S) was used in immunohistochemistry on mouse samples (fig 6). Cell (2016) ncbi
domestic rabbit monoclonal (D56D6)
  • western blot; zebrafish ; 1:1000; fig 3
In order to identify Fscn1 as a molecular linker between TGF-beta receptors and actin filaments, Cell Signaling Technology FOXA2 antibody (Cell Signaling, 8186S) was used in western blot on zebrafish samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D56D6)
  • immunocytochemistry; mouse; 1:200; fig 4
Cell Signaling Technology FOXA2 antibody (Cell signaling, D56D6) was used in immunocytochemistry on mouse samples at 1:200 (fig 4). Cell Reprogram (2016) ncbi
domestic rabbit monoclonal (D56D6)
  • western blot knockout validation; human; fig 6b
In order to identify transcription factors involved in pancreatic ductal adenocarcinoma pathogenesis, Cell Signaling Technology FOXA2 antibody (Cell Signaling, 8189) was used in western blot knockout validation on human samples (fig 6b). Am J Physiol Gastrointest Liver Physiol (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:200
Cell Signaling Technology FOXA2 antibody (Cell Signaling, 3143) was used in immunocytochemistry on human samples at 1:200. Nature (2016) ncbi
BD Biosciences
mouse monoclonal (N17-280)
  • flow cytometry; human; 1:80; fig s1
In order to assess the impact of thyroid dysregulation on the development of human embryonic stem cells-derived progenitor cells in vivo, BD Biosciences FOXA2 antibody (BD, 561589) was used in flow cytometry on human samples at 1:80 (fig s1). Diabetes (2016) ncbi
Articles Reviewed
  1. Tischler J, Swank Z, Hsiung H, Vianello S, Lutolf M, Maerkl S. An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates. Cell Rep Methods. 2022;2:100244 pubmed publisher
  2. Scheibner K, Schirge S, Burtscher I, Büttner M, Sterr M, Yang D, et al. Epithelial cell plasticity drives endoderm formation during gastrulation. Nat Cell Biol. 2021;23:692-703 pubmed publisher
  3. Monsivais D, Nagashima T, Prunskaite Hyyryläinen R, Nozawa K, Shimada K, Tang S, et al. Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis. Nat Commun. 2021;12:3386 pubmed publisher
  4. Olsen R, Ireland A, Kastner D, Groves S, Spainhower K, Pozo K, et al. ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer. Genes Dev. 2021;35:847-869 pubmed publisher
  5. Ni N, Fang X, Li Q. Functional similarity between TGF-beta type 2 and type 1 receptors in the female reproductive tract. Sci Rep. 2021;11:9294 pubmed publisher
  6. Kyprianou C, Christodoulou N, Hamilton R, Nahaboo W, Boomgaard D, Amadei G, et al. Basement membrane remodelling regulates mouse embryogenesis. Nature. 2020;582:253-258 pubmed publisher
  7. Hu H, Ji Q, Song M, Ren J, Liu Z, Wang Z, et al. ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin. Nucleic Acids Res. 2020;48:6001-6018 pubmed publisher
  8. Chen Y, Li Y, Chou C, Chiew M, Huang H, Ho J, et al. Control of matrix stiffness promotes endodermal lineage specification by regulating SMAD2/3 via lncRNA LINC00458. Sci Adv. 2020;6:eaay0264 pubmed publisher
  9. Ahfeldt T, Ordureau A, Bell C, Sarrafha L, Sun C, Piccinotti S, et al. Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons. Stem Cell Reports. 2020;14:75-90 pubmed publisher
  10. Sozen B, Cox A, De Jonghe J, Bao M, Hollfelder F, Glover D, et al. Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid. Dev Cell. 2019;51:698-712.e8 pubmed publisher
  11. Sergeeva O, Korinfskaya S, Kurochkin I, Zatsepin T. Long Noncoding RNA LL35/Falcor Regulates Expression of Transcription Factor Foxa2 in Hepatocytes in Normal and Fibrotic Mouse Liver. Acta Naturae. 2019;11:66-74 pubmed publisher
  12. Zhang J, Zhang Z, Sun J, Ma Q, Zhao W, Chen X, et al. MiR-942 regulates the function of breast cancer cell by targeting FOXA2. Biosci Rep. 2019;39: pubmed publisher
  13. van Veen J, Scherzer M, Boshuizen J, Chu M, Liu A, Landman A, et al. Mutationally-activated PI3'-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase. elife. 2019;8: pubmed publisher
  14. Menon V, Thomas R, Elgueta C, Horl M, Osborn T, Hallett P, et al. Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells. Stem Cells. 2019;37:1293-1306 pubmed publisher
  15. Oz Levi D, Olender T, Bar Joseph I, Zhu Y, Marek Yagel D, Barozzi I, et al. Noncoding deletions reveal a gene that is critical for intestinal function. Nature. 2019;: pubmed publisher
  16. Walter D, Yates T, Ruiz Torres M, Kim Kiselak C, Gudiel A, Deshpande C, et al. RB constrains lineage fidelity and multiple stages of tumour progression and metastasis. Nature. 2019;569:423-427 pubmed publisher
  17. Rajderkar S, Mann J, Panaretos C, Yumoto K, Li H, Mishina Y, et al. Trim33 is required for appropriate development of pre-cardiogenic mesoderm. Dev Biol. 2019;450:101-114 pubmed publisher
  18. Klein T, Günther K, Kwok C, Edenhofer F, Uceyler N. Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene. Stem Cell Res. 2018;31:222-226 pubmed publisher
  19. Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al. Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2018;172:423-438.e25 pubmed publisher
  20. Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, et al. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017;169:243-257.e25 pubmed publisher
  21. Jang S, Choubey S, Furchtgott L, Zou L, Doyle A, Menon V, et al. Dynamics of embryonic stem cell differentiation inferred from single-cell transcriptomics show a series of transitions through discrete cell states. elife. 2017;6: pubmed publisher
  22. La Manno G, Gyllborg D, Codeluppi S, Nishimura K, Salto C, Zeisel A, et al. Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells. Cell. 2016;167:566-580.e19 pubmed publisher
  23. Pettinato G, Ramanathan R, Fisher R, Mangino M, Zhang N, Wen X. Scalable Differentiation of Human iPSCs in a Multicellular Spheroid-based 3D Culture into Hepatocyte-like Cells through Direct Wnt/?-catenin Pathway Inhibition. Sci Rep. 2016;6:32888 pubmed publisher
  24. Liu Z, Ning G, Xu R, Cao Y, Meng A, Wang Q. Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation. Nat Commun. 2016;7:12603 pubmed publisher
  25. Pijuan Galitó S, Tamm C, Schuster J, Sobol M, Forsberg L, Merry C, et al. Human serum-derived protein removes the need for coating in defined human pluripotent stem cell culture. Nat Commun. 2016;7:12170 pubmed publisher
  26. Leon S, Fernandois D, Sull A, Sull J, Calder M, Hayashi K, et al. Beyond the brain-Peripheral kisspeptin signaling is essential for promoting endometrial gland development and function. Sci Rep. 2016;6:29073 pubmed publisher
  27. Shirouzu Y, Yanai G, Yang K, Sumi S. Effects of Activin in Embryoid Bodies Expressing Fibroblast Growth Factor 5. Cell Reprogram. 2016;18:171-86 pubmed publisher
  28. Miyawaki S, Kawamura Y, Oiwa Y, Shimizu A, Hachiya T, Bono H, et al. Tumour resistance in induced pluripotent stem cells derived from naked mole-rats. Nat Commun. 2016;7:11471 pubmed publisher
  29. Vorvis C, Hatziapostolou M, Mahurkar Joshi S, Koutsioumpa M, Williams J, Donahue T, et al. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. Am J Physiol Gastrointest Liver Physiol. 2016;310:G1124-37 pubmed publisher
  30. Sagi I, Chia G, Golan Lev T, Peretz M, Weissbein U, Sui L, et al. Derivation and differentiation of haploid human embryonic stem cells. Nature. 2016;532:107-11 pubmed publisher
  31. Bruin J, Saber N, O Dwyer S, Fox J, Mojibian M, Arora P, et al. Hypothyroidism Impairs Human Stem Cell-Derived Pancreatic Progenitor Cell Maturation in Mice. Diabetes. 2016;65:1297-309 pubmed publisher
  32. Guye P, Ebrahimkhani M, Kipniss N, Velazquez J, Schoenfeld E, Kiani S, et al. Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Nat Commun. 2016;7:10243 pubmed publisher
  33. Yu J, Ramasamy T, Murphy N, Holt M, Czapiewski R, Wei S, et al. PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation. Nat Commun. 2015;6:7212 pubmed publisher
  34. Gao Y, Bayless K, Li Q. TGFBR1 is required for mouse myometrial development. Mol Endocrinol. 2014;28:380-94 pubmed publisher