This is a Validated Antibody Database (VAD) review about human FOSB, based on 32 published articles (read how Labome selects the articles), using FOSB antibody in all methods. It is aimed to help Labome visitors find the most suited FOSB antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FOSB synonym: AP-1; G0S3; GOS3; GOSB

Santa Cruz Biotechnology
mouse monoclonal (C-10)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 4b
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, SC271243) was used in immunohistochemistry on mouse samples at 1:1000 (fig 4b). Cell Biosci (2022) ncbi
mouse monoclonal (E-8)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1b
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-166940) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1b). Dis Model Mech (2022) ncbi
mouse monoclonal (6-2H-2F)
  • western blot; mouse; loading ...; fig 3c
Santa Cruz Biotechnology FOSB antibody (Santa Cruz Biotechnology, sc-447) was used in western blot on mouse samples (fig 3c). Mol Med Rep (2021) ncbi
mouse monoclonal (E-8)
  • western blot; mouse; loading ...; fig 2c
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-166940) was used in western blot on mouse samples (fig 2c). Sci Rep (2021) ncbi
mouse monoclonal (E-8)
  • western blot; rat; loading ...; fig 3c
Santa Cruz Biotechnology FOSB antibody (Santa Cruz Biotechnology, sc-166940) was used in western blot on rat samples (fig 3c). Acta Neuropathol Commun (2021) ncbi
mouse monoclonal (C-10)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4a
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-271243) was used in immunohistochemistry - paraffin section on mouse samples (fig 4a). Oncogene (2021) ncbi
mouse monoclonal (E-8)
  • immunohistochemistry - paraffin section; mouse; 1:150; loading ...; fig 3b
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-166940) was used in immunohistochemistry - paraffin section on mouse samples at 1:150 (fig 3b). Nat Commun (2020) ncbi
mouse monoclonal (E-8)
  • immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig 6c
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-166940) was used in immunohistochemistry - free floating section on mouse samples at 1:1000 (fig 6c). J Clin Invest (2021) ncbi
mouse monoclonal (6-2H-2F)
  • western blot; mouse; loading ...; fig 2d
Santa Cruz Biotechnology FOSB antibody (Santa Cruz Biotechnology, sc-447) was used in western blot on mouse samples (fig 2d). Cell Death Dis (2020) ncbi
mouse monoclonal (E-8)
  • immunohistochemistry; rat; 1:1000; loading ...
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-166940) was used in immunohistochemistry on rat samples at 1:1000. Transl Psychiatry (2020) ncbi
mouse monoclonal (C-10)
  • immunohistochemistry; rat; 1:250; loading ...
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-271243) was used in immunohistochemistry on rat samples at 1:250. Transl Psychiatry (2020) ncbi
mouse monoclonal (E-8)
  • immunocytochemistry; human; loading ...; fig 4b
Santa Cruz Biotechnology FOSB antibody (Santa, sc-166940) was used in immunocytochemistry on human samples (fig 4b). Cancer Cell Int (2019) ncbi
mouse monoclonal (E-8)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 6c
Santa Cruz Biotechnology FOSB antibody (Santa Cruz Biotechnology, E-8) was used in immunohistochemistry - frozen section on mouse samples (fig 6c). elife (2019) ncbi
mouse monoclonal (E-8)
  • western blot; zebrafish ; 1:100; loading ...; fig 4k
Santa Cruz Biotechnology FOSB antibody (SantaCruz, sc-166940X) was used in western blot on zebrafish samples at 1:100 (fig 4k). Genetics (2017) ncbi
mouse monoclonal (C-10)
  • immunohistochemistry; mouse; loading ...; fig 1b
Santa Cruz Biotechnology FOSB antibody (SantaCruz, SC-271243) was used in immunohistochemistry on mouse samples (fig 1b). Neuron (2017) ncbi
mouse monoclonal (C-10)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4a
Santa Cruz Biotechnology FOSB antibody (Santa Cruz Biotechnology, sc-271243) was used in immunohistochemistry on mouse samples at 1:500 (fig 4a). Dis Model Mech (2017) ncbi
mouse monoclonal (C-10)
  • western blot; human; 1:1000; fig 4
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-271243) was used in western blot on human samples at 1:1000 (fig 4). Mol Med Rep (2016) ncbi
mouse monoclonal (E-8)
  • western blot; human; loading ...; fig 9a
In order to demonstrate that both Ras and Rap1 are required for cyclic adenosine monophosphate signaling to extracellular signal-regulated kinase, Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-166940) was used in western blot on human samples (fig 9a). J Biol Chem (2016) ncbi
mouse monoclonal (83B1138)
  • immunohistochemistry; mouse; 1:500; loading ...; fig s4
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-52) was used in immunohistochemistry on mouse samples at 1:500 (fig s4). Nat Commun (2016) ncbi
mouse monoclonal (6-2H-2F)
  • western blot; mouse; fig 5
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-447) was used in western blot on mouse samples (fig 5). Int J Mol Med (2016) ncbi
mouse monoclonal (83B1138)
  • immunohistochemistry; mouse; 1:5000; loading ...; fig 6a
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc52) was used in immunohistochemistry on mouse samples at 1:5000 (fig 6a). Cereb Cortex (2016) ncbi
mouse monoclonal (6-2H-2F)
  • EMSA; human; loading ...; fig 4b
Santa Cruz Biotechnology FOSB antibody (Santa Cruz Biotechnology, sc-447) was used in EMSA on human samples (fig 4b). Int J Mol Med (2015) ncbi
mouse monoclonal (6-2H-2F)
  • western blot; human; fig 2
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-447) was used in western blot on human samples (fig 2). Arch Med Sci (2015) ncbi
mouse monoclonal (E-8)
  • immunohistochemistry - paraffin section; rat; 1:5000
Santa Cruz Biotechnology FOSB antibody (Santa Cruz, sc-166940) was used in immunohistochemistry - paraffin section on rat samples at 1:5000. Neuroscience (2015) ncbi
mouse monoclonal (C-10)
  • EMSA; human
Santa Cruz Biotechnology FOSB antibody (Santa Cruz Biotechnology, sc271243) was used in EMSA on human samples . Int Immunol (2014) ncbi
Abcam
domestic rabbit monoclonal (EPR15905)
  • immunohistochemistry; mouse; 1:2000; loading ...; fig 4a
Abcam FOSB antibody (Abcam, ab184938) was used in immunohistochemistry on mouse samples at 1:2000 (fig 4a). J Neurosci (2018) ncbi
mouse monoclonal (83B1138)
  • immunohistochemistry; rat; 1:500; loading ...; fig 8a
In order to elucidate the effects of endomorphin-2 on substance P release within lamina I of the spinal dorsal horn in rats with diabetic neuropathic pain, Abcam FOSB antibody (abcam, ab11959) was used in immunohistochemistry on rat samples at 1:500 (fig 8a). Front Mol Neurosci (2016) ncbi
mouse monoclonal (83B1138)
  • immunohistochemistry - frozen section; rat; 1:500
Abcam FOSB antibody (Abcam, ab11959) was used in immunohistochemistry - frozen section on rat samples at 1:500. Front Neural Circuits (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (5G4)
  • immunohistochemistry - paraffin section; mouse; fig 6i
  • immunohistochemistry - paraffin section; human; fig 6j
Cell Signaling Technology FOSB antibody (CST, 2251) was used in immunohistochemistry - paraffin section on mouse samples (fig 6i) and in immunohistochemistry - paraffin section on human samples (fig 6j). Oncogene (2021) ncbi
domestic rabbit monoclonal (5G4)
  • western blot; human; 1:1000; loading ...; fig 2c
In order to report FOSL1 as a common transcriptional signature across mutant KRAS cancers of distinct tissue origin, Cell Signaling Technology FOSB antibody (Cell Signaling, 2251) was used in western blot on human samples at 1:1000 (fig 2c). Nat Commun (2017) ncbi
domestic rabbit monoclonal (5G4)
  • western blot; human; 1:1000
In order to show that tamoxifen prevents myofibroblast differentiation, Cell Signaling Technology FOSB antibody (Cell Signaling, 2251) was used in western blot on human samples at 1:1000. J Cell Physiol (2015) ncbi
domestic rabbit monoclonal (5G4)
  • chromatin immunoprecipitation; human; fig 2
  • immunocytochemistry; human; fig 7
  • western blot; human; fig 1
Cell Signaling Technology FOSB antibody (Cell signaling, 5G4) was used in chromatin immunoprecipitation on human samples (fig 2), in immunocytochemistry on human samples (fig 7) and in western blot on human samples (fig 1). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (5G4)
  • western blot; mouse; 1:500
Cell Signaling Technology FOSB antibody (Cell Signaling, 2251S) was used in western blot on mouse samples at 1:500. PLoS ONE (2014) ncbi
Articles Reviewed
  1. Singh I, Wang L, Xia B, Liu J, Tahiri A, El Ouaamari A, et al. Activation of arcuate nucleus glucagon-like peptide-1 receptor-expressing neurons suppresses food intake. Cell Biosci. 2022;12:178 pubmed publisher
  2. Owaki T, Kamimura K, Ko M, Nagayama I, Nagoya T, Shibata O, et al. Involvement of the liver-gut peripheral neural axis in nonalcoholic fatty liver disease pathologies via hepatic HTR2A. Dis Model Mech. 2022;15: pubmed publisher
  3. Yuan S, Zhang P, Wen L, Jia S, Wu Y, Zhang Z, et al. miR-22 promotes stem cell traits via activating Wnt/β-catenin signaling in cutaneous squamous cell carcinoma. Oncogene. 2021;40:5799-5813 pubmed publisher
  4. Kim M, Kim J, Hong S, Kwon B, Kim E, Jung H, et al. Effects of Melandrium firmum Rohrbach on RANKL‑induced osteoclast differentiation and OVX rats. Mol Med Rep. 2021;24: pubmed publisher
  5. Liu Y, Zienkiewicz J, Boyd K, Smith T, Xu Z, Hawiger J. Hyperlipidemic hypersensitivity to lethal microbial inflammation and its reversal by selective targeting of nuclear transport shuttles. Sci Rep. 2021;11:11907 pubmed publisher
  6. Sadeghi M, Hemmati S, Mohammadi S, Yousefi Manesh H, Vafaei A, Zare M, et al. Chronically altered NMDAR signaling in epilepsy mediates comorbid depression. Acta Neuropathol Commun. 2021;9:53 pubmed publisher
  7. Riedel M, Berthelsen M, Cai H, Haldrup J, Borre M, Paludan S, et al. In vivo CRISPR inactivation of Fos promotes prostate cancer progression by altering the associated AP-1 subunit Jun. Oncogene. 2021;40:2437-2447 pubmed publisher
  8. Zhang J, Chen D, Sweeney P, Yang Y. An excitatory ventromedial hypothalamus to paraventricular thalamus circuit that suppresses food intake. Nat Commun. 2020;11:6326 pubmed publisher
  9. Borie A, Dromard Y, Guillon G, Olma A, Manning M, Muscatelli F, et al. Correction of vasopressin deficit in the lateral septum ameliorates social deficits of mouse autism model. J Clin Invest. 2021;131: pubmed publisher
  10. Du T, Yan Z, Zhu S, Chen G, Wang L, Ye Z, et al. QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism. Cell Death Dis. 2020;11:330 pubmed publisher
  11. Cohen S, Matar M, Vainer E, Zohar J, Kaplan Z, Cohen H. Significance of the orexinergic system in modulating stress-related responses in an animal model of post-traumatic stress disorder. Transl Psychiatry. 2020;10:10 pubmed publisher
  12. Del Mar Díaz González S, Rodríguez Aguilar E, Meneses Acosta A, Valadez Graham V, Deas J, Gómez Cerón C, et al. Transregulation of microRNA miR-21 promoter by AP-1 transcription factor in cervical cancer cells. Cancer Cell Int. 2019;19:214 pubmed publisher
  13. Chowdhury S, Hung C, Izawa S, Inutsuka A, Kawamura M, Kawashima T, et al. Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice. elife. 2019;8: pubmed publisher
  14. Niraula A, Wang Y, Godbout J, Sheridan J. Corticosterone Production during Repeated Social Defeat Causes Monocyte Mobilization from the Bone Marrow, Glucocorticoid Resistance, and Neurovascular Adhesion Molecule Expression. J Neurosci. 2018;38:2328-2340 pubmed publisher
  15. Pena I, Roussel Y, Daniel K, Mongeon K, Johnstone D, Weinschutz Mendes H, et al. Pyridoxine-Dependent Epilepsy in Zebrafish Caused by Aldh7a1 Deficiency. Genetics. 2017;207:1501-1518 pubmed publisher
  16. Liu J, Conde K, Zhang P, Lilascharoen V, Xu Z, Lim B, et al. Enhanced AMPA Receptor Trafficking Mediates the Anorexigenic Effect of Endogenous Glucagon-like Peptide-1 in the Paraventricular Hypothalamus. Neuron. 2017;96:897-909.e5 pubmed publisher
  17. Vallejo A, Perurena N, Guruceaga E, Mazur P, Martínez Canarias S, Zandueta C, et al. An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer. Nat Commun. 2017;8:14294 pubmed publisher
  18. Ladrón de Guevara Miranda D, Millón C, Rosell Valle C, Pérez Fernández M, Missiroli M, Serrano A, et al. Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult neurogenesis. Dis Model Mech. 2017;10:323-336 pubmed publisher
  19. Wan F, Bai Y, Kou Z, Zhang T, Li H, Wang Y, et al. Endomorphin-2 Inhibition of Substance P Signaling within Lamina I of the Spinal Cord Is Impaired in Diabetic Neuropathic Pain Rats. Front Mol Neurosci. 2016;9:167 pubmed publisher
  20. Shang W, Zhao L, Dong X, Zhao Z, Li J, Zhang B, et al. Curcumin inhibits osteoclastogenic potential in PBMCs from rheumatoid arthritis patients via the suppression of MAPK/RANK/c-Fos/NFATc1 signaling pathways. Mol Med Rep. 2016;14:3620-6 pubmed publisher
  21. Li Y, Dillon T, Takahashi M, Earley K, Stork P. Protein Kinase A-independent Ras Protein Activation Cooperates with Rap1 Protein to Mediate Activation of the Extracellular Signal-regulated Kinases (ERK) by cAMP. J Biol Chem. 2016;291:21584-21595 pubmed
  22. Roman C, Derkach V, Palmiter R. Genetically and functionally defined NTS to PBN brain circuits mediating anorexia. Nat Commun. 2016;7:11905 pubmed publisher
  23. Kim J, Kim E, Lee B, Min J, Song D, Lim J, et al. The effects of Lycii Radicis Cortex on RANKL-induced osteoclast differentiation and activation in RAW 264.7 cells. Int J Mol Med. 2016;37:649-58 pubmed publisher
  24. Wagener R, Witte M, Guy J, Mingo Moreno N, Kügler S, Staiger J. Thalamocortical Connections Drive Intracortical Activation of Functional Columns in the Mislaminated Reeler Somatosensory Cortex. Cereb Cortex. 2016;26:820-37 pubmed publisher
  25. Liu B, Wu S, Han L, Zhang C. β-catenin signaling induces the osteoblastogenic differentiation of human pre-osteoblastic and bone marrow stromal cells mainly through the upregulation of osterix expression. Int J Mol Med. 2015;36:1572-82 pubmed publisher
  26. Lan G, Yang L, Xie X, Peng L, Wang Y. MicroRNA-490-5p is a novel tumor suppressor targeting c-FOS in human bladder cancer. Arch Med Sci. 2015;11:561-9 pubmed publisher
  27. Carthy J, Sundqvist A, Heldin A, van Dam H, Kletsas D, Heldin C, et al. Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2. J Cell Physiol. 2015;230:3084-92 pubmed publisher
  28. Liu W, Crews F. Adolescent intermittent ethanol exposure enhances ethanol activation of the nucleus accumbens while blunting the prefrontal cortex responses in adult rat. Neuroscience. 2015;293:92-108 pubmed publisher
  29. Butin Israeli V, Adam S, Jain N, Otte G, Neems D, Wiesmüller L, et al. Role of lamin b1 in chromatin instability. Mol Cell Biol. 2015;35:884-98 pubmed publisher
  30. Yin J, Wu H, Dong Y, Zhang T, Wang J, Zhang Y, et al. Neurochemical properties of BDNF-containing neurons projecting to rostral ventromedial medulla in the ventrolateral periaqueductal gray. Front Neural Circuits. 2014;8:137 pubmed publisher
  31. Yan T, Li L, Sun B, Liu F, Yang P, Chen T, et al. Luteolin inhibits behavioral sensitization by blocking methamphetamine-induced MAPK pathway activation in the caudate putamen in mice. PLoS ONE. 2014;9:e98981 pubmed publisher
  32. Davidson C, Cameron L, Burshtyn D. The AP-1 transcription factor JunD activates the leukocyte immunoglobulin-like receptor 1 distal promoter. Int Immunol. 2014;26:21-33 pubmed publisher