This is a Validated Antibody Database (VAD) review about human FNDC5, based on 4 published articles (read how Labome selects the articles), using FNDC5 antibody in all methods. It is aimed to help Labome visitors find the most suited FNDC5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FNDC5 synonym: FRCP2; irisin

Knockout validation
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2d
Abcam FNDC5 antibody (Abcam, ab131390) was used in western blot knockout validation on mouse samples at 1:1000 (fig 2d). Theranostics (2021) ncbi
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2d
Abcam FNDC5 antibody (Abcam, ab131390) was used in western blot knockout validation on mouse samples at 1:1000 (fig 2d). Theranostics (2021) ncbi
domestic rabbit monoclonal (EPR12209)
  • western blot; mouse; loading ...; fig 4
Abcam FNDC5 antibody (Abcam, Ab174833) was used in western blot on mouse samples (fig 4). Physiol Rep (2017) ncbi
domestic rabbit monoclonal (EPR12209)
  • western blot; pigs ; loading ...; fig 6e
Abcam FNDC5 antibody (Abcam, ab174833) was used in western blot on pigs samples (fig 6e). Oncotarget (2017) ncbi
domestic rabbit monoclonal (EPR12209)
  • immunohistochemistry - paraffin section; rat; 1:100
  • western blot; rat; 1:1000; fig 4b
In order to analyze FNDC5, produced in the stomach, and its role in body composition, Abcam FNDC5 antibody (Abcam, ab-174833) was used in immunohistochemistry - paraffin section on rat samples at 1:100 and in western blot on rat samples at 1:1000 (fig 4b). Sci Rep (2016) ncbi
Articles Reviewed
  1. Li D, Sun S, Fu J, Ouyang S, Zhao Q, Su L, et al. NAD+-boosting therapy alleviates nonalcoholic fatty liver disease via stimulating a novel exerkine Fndc5/irisin. Theranostics. 2021;11:4381-4402 pubmed publisher
  2. Guilford B, Parson J, Grote C, Vick S, Ryals J, Wright D. Increased FNDC5 is associated with insulin resistance in high fat-fed mice. Physiol Rep. 2017;5: pubmed publisher
  3. Cai C, Qian L, Jiang S, Sun Y, Wang Q, Ma D, et al. Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs. Oncotarget. 2017;8:34911-34922 pubmed publisher
  4. Barja Fernández S, Folgueira C, Castelao C, Al Massadi O, Bravo S, Garcia Caballero T, et al. FNDC5 is produced in the stomach and associated to body composition. Sci Rep. 2016;6:23067 pubmed publisher