This is a Validated Antibody Database (VAD) review about human FLNA, based on 20 published articles (read how Labome selects the articles), using FLNA antibody in all methods. It is aimed to help Labome visitors find the most suited FLNA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FLNA synonym: ABP-280; ABPX; CSBS; CVD1; FGS2; FLN; FLN-A; FLN1; FMD; MNS; NHBP; OPD; OPD1; OPD2; XLVD; XMVD

Abcam
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; loading ...
Abcam FLNA antibody (Abcam, ab51217) was used in immunohistochemistry - paraffin section on human samples at 1:200. Int J Mol Sci (2022) ncbi
domestic rabbit monoclonal (EP2405Y)
  • western blot; human; loading ...; fig 5a
Abcam FLNA antibody (Abcam, ab76289) was used in western blot on human samples (fig 5a). Front Cardiovasc Med (2021) ncbi
domestic rabbit monoclonal (EP2405Y)
  • western blot; mouse; 1:1000; loading ...; fig 6g
Abcam FLNA antibody (Abcam, ab76289) was used in western blot on mouse samples at 1:1000 (fig 6g). Nat Commun (2021) ncbi
domestic rabbit monoclonal (EP2405Y)
  • immunocytochemistry; human; 1:100; loading ...; fig 5d
  • western blot; human; 1:10,000; loading ...; fig 5b
Abcam FLNA antibody (Abcam, ab76289) was used in immunocytochemistry on human samples at 1:100 (fig 5d) and in western blot on human samples at 1:10,000 (fig 5b). Nat Commun (2018) ncbi
domestic rabbit monoclonal (EP2405Y)
  • western blot; human; 1:10,000; loading ...; fig 1c
  • western blot; mouse; 1:10,000; loading ...; fig 1b
In order to demonstrate that actin-binding protein filamin A interacts with actin-nucleating protein formin 2, Abcam FLNA antibody (Abcam, ab76289) was used in western blot on human samples at 1:10,000 (fig 1c) and in western blot on mouse samples at 1:10,000 (fig 1b). Development (2016) ncbi
domestic rabbit monoclonal (EP2405Y)
  • immunohistochemistry; human; loading ...; fig 6a
In order to elucidate how cytoskeletal filamin A suppresses cell proliferation, Abcam FLNA antibody (Abcam, ab76289) was used in immunohistochemistry on human samples (fig 6a). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (EP2405Y)
  • immunocytochemistry; human; 1:1000
Abcam FLNA antibody (Abcam, ab76289) was used in immunocytochemistry on human samples at 1:1000. J Cell Physiol (2014) ncbi
domestic rabbit monoclonal (EP2405Y)
  • western blot; mouse
In order to study the roles of calpain-1 and calpain-2 in murine aortic aneurysms induced by angiotensin II, Abcam FLNA antibody (Abcam, ab76289) was used in western blot on mouse samples . PLoS ONE (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (E-3)
  • immunocytochemistry; human; 1:100; loading ...; fig 7b
Santa Cruz Biotechnology FLNA antibody (Santa Cruz, sc-17749) was used in immunocytochemistry on human samples at 1:100 (fig 7b). Nat Commun (2018) ncbi
mouse monoclonal (G-9)
  • western blot; mouse; loading ...; fig 5a
In order to show that PTI-125 therapeutically alters filamin A and reverses proteopathy, Santa Cruz Biotechnology FLNA antibody (SantaCruz, SC-271440) was used in western blot on mouse samples (fig 5a). Neurobiol Aging (2017) ncbi
mouse monoclonal (E-3)
  • western blot; human; 1:2000; loading ...; fig 1e
Santa Cruz Biotechnology FLNA antibody (Santa Cruz, sc-17749) was used in western blot on human samples at 1:2000 (fig 1e). J Cell Sci (2017) ncbi
mouse monoclonal (PM6/317)
  • western blot; human; 1:1000; loading ...; fig 1c
  • immunocytochemistry; mouse; 1:100; loading ...; fig s1a
  • immunohistochemistry; mouse; 1:100; loading ...; fig 1f
  • western blot; mouse; 1:1000; loading ...; fig 1b
In order to demonstrate that actin-binding protein filamin A interacts with actin-nucleating protein formin 2, Santa Cruz Biotechnology FLNA antibody (Santa Cruz, sc-58764) was used in western blot on human samples at 1:1000 (fig 1c), in immunocytochemistry on mouse samples at 1:100 (fig s1a), in immunohistochemistry on mouse samples at 1:100 (fig 1f) and in western blot on mouse samples at 1:1000 (fig 1b). Development (2016) ncbi
mouse monoclonal (E-3)
  • immunocytochemistry; human; 1:100
Santa Cruz Biotechnology FLNA antibody (Santa Cruz Biotechnology, sc-17749) was used in immunocytochemistry on human samples at 1:100. AIDS (2014) ncbi
Abnova
mouse monoclonal (4E10-1B2)
  • western blot; human; 1:1000; loading ...; fig 3d
Abnova FLNA antibody (Abnova, H00002316-M01) was used in western blot on human samples at 1:1000 (fig 3d). Biol Open (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4d
In order to explore the role of TPM4 in platelet biogenesis, Invitrogen FLNA antibody (Thermo Scientific, PA5-29598) was used in western blot on human samples (fig 4d). J Clin Invest (2017) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
Cell Signaling Technology FLNA antibody (Cell Signaling Technology, 4762) was used . Theranostics (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4d
Cell Signaling Technology FLNA antibody (CST, 4762) was used in western blot on mouse samples at 1:1000 (fig 4d). Transl Psychiatry (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology FLNA antibody (Cell Signaling Technology, 4761) was used in western blot on human samples (fig 2a). Infect Immun (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4a
Cell Signaling Technology FLNA antibody (Cell Signalling Technology, 4761S) was used in western blot on mouse samples at 1:1000 (fig 4a). Front Cell Neurosci (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5a
In order to study the nuclear functions of SQSTM1, Cell Signaling Technology FLNA antibody (Cell Signaling, 4762) was used in western blot on mouse samples at 1:1000 (fig 5a). Autophagy (2016) ncbi
MilliporeSigma
mouse monoclonal (PM6/317)
  • immunocytochemistry; dogs; 1:100; fig 5
MilliporeSigma FLNA antibody (Sigma, F6682) was used in immunocytochemistry on dogs samples at 1:100 (fig 5). Sci Rep (2016) ncbi
mouse monoclonal (PM6/317)
  • immunocytochemistry; dogs; fig 5
MilliporeSigma FLNA antibody (Sigma-Aldrich, F6682) was used in immunocytochemistry on dogs samples (fig 5). Mol Biol Cell (2016) ncbi
Articles Reviewed
  1. Nishtala K, Panigrahi T, Shetty R, Kumar D, Khamar P, Mohan R, et al. Quantitative Proteomics Reveals Molecular Network Driving Stromal Cell Differentiation: Implications for Corneal Wound Healing. Int J Mol Sci. 2022;23: pubmed publisher
  2. Chen Y, Wei X, Zhang Z, He Y, Huo B, Guo X, et al. Downregulation of Filamin a Expression in the Aorta Is Correlated With Aortic Dissection. Front Cardiovasc Med. 2021;8:690846 pubmed publisher
  3. Chen L, Luo S, Dupre A, Vasoya R, Parthasarathy A, Aita R, et al. The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac. Nat Commun. 2021;12:2886 pubmed publisher
  4. Wang H, Guo S, Kim S, Shao F, Ho J, Wong K, et al. Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel. Theranostics. 2021;11:2442-2459 pubmed publisher
  5. Amal H, Gong G, Gjoneska E, Lewis S, Wishnok J, Tsai L, et al. S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy. Transl Psychiatry. 2019;9:44 pubmed publisher
  6. Bhalla M, Van Ngo H, Gyanwali G, Ireton K. The Host Scaffolding Protein Filamin A and the Exocyst Complex Control Exocytosis during InlB-Mediated Entry of Listeria monocytogenes. Infect Immun. 2019;87: pubmed publisher
  7. Latham S, Ehmke N, Reinke P, Taft M, Eicke D, Reindl T, et al. Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia. Nat Commun. 2018;9:4250 pubmed publisher
  8. O Neill A, Kyrousi C, Einsiedler M, Burtscher I, Drukker M, Markie D, et al. Mob2 Insufficiency Disrupts Neuronal Migration in the Developing Cortex. Front Cell Neurosci. 2018;12:57 pubmed publisher
  9. Wang H, Lee K, Pei Z, Khan A, Bakshi K, Burns L. PTI-125 binds and reverses an altered conformation of filamin A to reduce Alzheimer's disease pathogenesis. Neurobiol Aging. 2017;55:99-114 pubmed publisher
  10. Ludwig A, Nguyen T, Leong D, Ravi L, Tan B, Sandin S, et al. Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly. J Cell Sci. 2017;130:1037-1050 pubmed publisher
  11. Pleines I, Woods J, Chappaz S, Kew V, Foad N, Ballester Beltrán J, et al. Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia. J Clin Invest. 2017;127:814-829 pubmed publisher
  12. Lian G, Dettenhofer M, Lu J, Downing M, Chenn A, Wong T, et al. Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway. Development. 2016;143:4509-4520 pubmed
  13. Gay O, Gilquin B, Assard N, Stuelsatz P, Delphin C, Lachuer J, et al. Refilins are short-lived Actin-bundling proteins that regulate lamellipodium protrusion dynamics. Biol Open. 2016;5:1351-1361 pubmed publisher
  14. Wang J, Zhao S, Wei Y, Zhou Y, Shore P, Deng W. Cytoskeletal Filamin A Differentially Modulates RNA Polymerase III Gene Transcription in Transformed Cell Lines. J Biol Chem. 2016;291:25239-25246 pubmed
  15. Hewitt G, Carroll B, Sarallah R, Correia Melo C, Ogrodnik M, Nelson G, et al. SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. Autophagy. 2016;12:1917-1930 pubmed
  16. Chiba T, Ishihara E, Miyamura N, Narumi R, Kajita M, Fujita Y, et al. MDCK cells expressing constitutively active Yes-associated protein (YAP) undergo apical extrusion depending on neighboring cell status. Sci Rep. 2016;6:28383 pubmed publisher
  17. Yamamoto S, Yako Y, Fujioka Y, Kajita M, Kameyama T, Kon S, et al. A role of the sphingosine-1-phosphate (S1P)-S1P receptor 2 pathway in epithelial defense against cancer (EDAC). Mol Biol Cell. 2016;27:491-9 pubmed publisher
  18. Lopez Camacho C, Van Wijnen A, Lian J, Stein J, Stein G. Core binding factor ? (CBF?) is retained in the midbody during cytokinesis. J Cell Physiol. 2014;229:1466-74 pubmed publisher
  19. Dever S, COSTIN B, Xu R, El Hage N, Balinang J, Samoshkin A, et al. Differential expression of the alternatively spliced OPRM1 isoform ?-opioid receptor-1K in HIV-infected individuals. AIDS. 2014;28:19-30 pubmed publisher
  20. Subramanian V, Moorleghen J, Balakrishnan A, Howatt D, Chishti A, Uchida H. Calpain-2 compensation promotes angiotensin II-induced ascending and abdominal aortic aneurysms in calpain-1 deficient mice. PLoS ONE. 2013;8:e72214 pubmed publisher