This is a Validated Antibody Database (VAD) review about human FKBP51, based on 10 published articles (read how Labome selects the articles), using FKBP51 antibody in all methods. It is aimed to help Labome visitors find the most suited FKBP51 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FKBP51 synonym: AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D5G2)
  • western blot knockout validation; human; 1:1000; fig s3c, s3d
Cell Signaling Technology FKBP51 antibody (Cell Signaling, 12210) was used in western blot knockout validation on human samples at 1:1000 (fig s3c, s3d). Signal Transduct Target Ther (2021) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2a
Abcam FKBP51 antibody (Abcam, 2901) was used in western blot on human samples at 1:1000 (fig 2a). Mol Ther Nucleic Acids (2021) ncbi
domestic rabbit monoclonal (EPR6617)
  • immunohistochemistry - paraffin section; human; 1:250; loading ...; fig 1a
  • western blot; human; loading ...; fig 1b
Abcam FKBP51 antibody (Abcam, ab126715) was used in immunohistochemistry - paraffin section on human samples at 1:250 (fig 1a) and in western blot on human samples (fig 1b). Exp Ther Med (2020) ncbi
domestic rabbit monoclonal (EPR6617)
  • western blot; human; loading ...; fig 4c
Abcam FKBP51 antibody (Abcam, ab126715) was used in western blot on human samples (fig 4c). Cancer Sci (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; rat; 1:250; loading ...; fig 9a
In order to test if a Western-like high-fat diet predisposes rats to post-traumatic stress responsivity, Abcam FKBP51 antibody (Abcam, ab2901) was used in immunohistochemistry - frozen section on rat samples at 1:250 (fig 9a). Eneuro (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 6a
In order to test if a Western-like high-fat diet predisposes rats to post-traumatic stress responsivity, Invitrogen FKBP51 antibody (ThermoFisher, PA1-020) was used in western blot on rat samples at 1:1000 (fig 6a). Eneuro (2016) ncbi
domestic rabbit polyclonal
In order to determine if HIF-1 links glucocorticoids and oxidative stress, Invitrogen FKBP51 antibody (ThermoScientific, pa1-020) was used . Neurosci Lett (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-4)
  • immunoprecipitation; human; loading ...; fig 1c
Santa Cruz Biotechnology FKBP51 antibody (Santa Cruz, sc-271547) was used in immunoprecipitation on human samples (fig 1c). Cancer Sci (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D5G2)
  • western blot knockout validation; human; 1:1000; fig s3c, s3d
Cell Signaling Technology FKBP51 antibody (Cell Signaling, 12210) was used in western blot knockout validation on human samples at 1:1000 (fig s3c, s3d). Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (D5G2)
  • western blot; human; 1:1000
Cell Signaling Technology FKBP51 antibody (CST, 12210) was used in western blot on human samples at 1:1000. Nat Commun (2021) ncbi
domestic rabbit monoclonal (D5G2)
  • western blot; human; 1:1000; loading ...; fig 5b
Cell Signaling Technology FKBP51 antibody (Cell Signaling, 12210S) was used in western blot on human samples at 1:1000 (fig 5b). Mol Cancer Ther (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 1s1c, 3c
Cell Signaling Technology FKBP51 antibody (Cell Signaling, 8245) was used in western blot on human samples at 1:500 (fig 1s1c, 3c). elife (2019) ncbi
domestic rabbit monoclonal (D5G2)
  • western blot; human; fig 7b
In order to elucidate the mechanisms by which cancer cells overcome anoikis, Cell Signaling Technology FKBP51 antibody (Cell Signaling Technology, 12210) was used in western blot on human samples (fig 7b). Cell Death Differ (2016) ncbi
Articles Reviewed
  1. Luo R, Fan Y, Yang J, Ye M, Zhang D, Guo K, et al. A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. Signal Transduct Target Ther. 2021;6:325 pubmed publisher
  2. Tang X, Li G, Shi L, Su F, Qian M, Liu Z, et al. Combined intermittent fasting and ERK inhibition enhance the anti-tumor effects of chemotherapy via the GSK3β-SIRT7 axis. Nat Commun. 2021;12:5058 pubmed publisher
  3. Corbin J, Georgescu C, Wren J, Xu C, Asch A, Ruiz Echevarría M. Seed-mediated RNA interference of androgen signaling and survival networks induces cell death in prostate cancer cells. Mol Ther Nucleic Acids. 2021;24:337-351 pubmed publisher
  4. Chen Y, Liu Z, Wang Y, Zhuang J, Peng Y, Mo X, et al. FKBP51 induces p53-dependent apoptosis and enhances drug sensitivity of human non-small-cell lung cancer cells. Exp Ther Med. 2020;19:2236-2242 pubmed publisher
  5. Mao N, Gao D, Hu W, Hieronymus H, Wang S, Lee Y, et al. Aberrant Expression of ERG Promotes Resistance to Combined PI3K and AR Pathway Inhibition through Maintenance of AR Target Genes. Mol Cancer Ther. 2019;18:1577-1586 pubmed publisher
  6. Lee E, Wongvipat J, Choi D, Wang P, Lee Y, Zheng D, et al. GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistance. elife. 2019;8: pubmed publisher
  7. Takaoka M, Ito S, Miki Y, Nakanishi A. FKBP51 regulates cell motility and invasion via RhoA signaling. Cancer Sci. 2017;108:380-389 pubmed publisher
  8. Kalyan Masih P, Vega Torres J, Miles C, Haddad E, Rainsbury S, Baghchechi M, et al. Western High-Fat Diet Consumption during Adolescence Increases Susceptibility to Traumatic Stress while Selectively Disrupting Hippocampal and Ventricular Volumes. Eneuro. 2016;3: pubmed
  9. Mason J, Davison Versagli C, Leliaert A, Pape D, McCallister C, Zuo J, et al. Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells. Cell Death Differ. 2016;23:1271-82 pubmed publisher
  10. Harrell C, Rowson S, Neigh G. Pharmacological stimulation of hypoxia inducible factor-1α facilitates the corticosterone response to a mild acute stressor. Neurosci Lett. 2015;600:75-9 pubmed publisher