This is a Validated Antibody Database (VAD) review about human FIS1, based on 14 published articles (read how Labome selects the articles), using FIS1 antibody in all methods. It is aimed to help Labome visitors find the most suited FIS1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FIS1 synonym: CGI-135; TTC11; mitochondrial fission 1 protein; FIS1 homolog; H_NH0132A01.6; TPR repeat protein 11; fission 1 (mitochondrial outer membrane) homolog; hFis1; mitochondrial fission molecule; tetratricopeptide repeat domain 11; tetratricopeptide repeat protein 11

Abcam
rabbit polyclonal
  • western blot; mouse; loading ...; fig s1c
Abcam FIS1 antibody (Abcam, ab71498) was used in western blot on mouse samples (fig s1c). Cell Rep (2018) ncbi
rabbit monoclonal (EPR8412)
  • western blot; human; 1:1000; fig s1
Abcam FIS1 antibody (Abcam, ab156865) was used in western blot on human samples at 1:1000 (fig s1). Autophagy (2016) ncbi
rabbit polyclonal
  • western blot; human; fig s2
Abcam FIS1 antibody (abcam, ab71498) was used in western blot on human samples (fig s2). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; rat
  • western blot; human
Abcam FIS1 antibody (Abcam, ab71498) was used in western blot on rat samples and in western blot on human samples . Cell Death Dis (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-10)
  • western blot; human; loading ...; fig 4a, 8a
Santa Cruz Biotechnology FIS1 antibody (Santa Cruz, sc-376469) was used in western blot on human samples (fig 4a, 8a). Nucleic Acids Res (2019) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s7e
In order to investigate how LACTB suppresses breast cancer cell growth, Proteintech Group FIS1 antibody (Proteintech, 10956-1-AP) was used in western blot on human samples at 1:1000 (fig s7e). Nature (2017) ncbi
rabbit polyclonal
  • western blot; mouse; fig s2
In order to analyze delay of neurodegeneration by preventing stress-induced OPA1 processing in mitochondria by loss of OMA1, Proteintech Group FIS1 antibody (ProteinTech, 10956-1-AP) was used in western blot on mouse samples (fig s2). J Cell Biol (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4
Proteintech Group FIS1 antibody (Proteintech, 10956-1-AP) was used in western blot on mouse samples (fig 4). Mol Psychiatry (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 2
Proteintech Group FIS1 antibody (Proteintech, 10956-1-AP) was used in western blot on mouse samples (fig 2). Autophagy (2014) ncbi
Invitrogen
rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 5c
In order to study the role of succinyl-CoA synthase ADP-forming beta subunit in mtDNA stability and mitochondrial dynamics, Invitrogen FIS1 antibody (Thermo Scientific, PA1-41082) was used in western blot on mouse samples at 1:500 (fig 5c). Sci Rep (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
In order to determine how mitochondrial homeostasis is affected by ubiquitin-mediated regulation of E3 ligase GP78 by MGRN1 in trans, Invitrogen FIS1 antibody (Thermo Scientific, PA22142) was used in western blot on human samples at 1:1000 (fig 3). J Cell Sci (2016) ncbi
GeneTex
rabbit polyclonal
  • western blot; human; fig 1
In order to characterize how dengue virus cleaves mitofusins and impairs mitochondrial fusion, GeneTex FIS1 antibody (GeneTex, GTX111010) was used in western blot on human samples (fig 1). PLoS Pathog (2015) ncbi
MilliporeSigma
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 4b
In order to test if the severe neurodegeneration observed in mutUNG1-expressing mice is prevented by a ketogenic diet, MilliporeSigma FIS1 antibody (Sigma, HPA017430) was used in western blot on mouse samples at 1:1000 (fig 4b). Neurobiol Aging (2016) ncbi
EMD Millipore
mouse monoclonal (4D1.1)
  • western blot; mouse; 1:500; fig 6
In order to study affects of acute minimization of brown adipose tissue function by increased reliance on muscle based thermogenesis, EMD Millipore FIS1 antibody (EMD Millipore, MABN391) was used in western blot on mouse samples at 1:500 (fig 6). J Biol Chem (2016) ncbi
Articles Reviewed
  1. Zheng J, Croteau D, Bohr V, Akbari M. Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells. Nucleic Acids Res. 2019;: pubmed publisher
  2. Simula L, Pacella I, Colamatteo A, Procaccini C, Cancila V, Bordi M, et al. Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming. Cell Rep. 2018;25:3059-3073.e10 pubmed publisher
  3. Zhao Y, Tian J, Sui S, Yuan X, Chen H, Qu C, et al. Loss of succinyl-CoA synthase ADP-forming β subunit disrupts mtDNA stability and mitochondrial dynamics in neurons. Sci Rep. 2017;7:7169 pubmed publisher
  4. Keckesova Z, Donaher J, De Cock J, Freinkman E, Lingrell S, Bachovchin D, et al. LACTB is a tumour suppressor that modulates lipid metabolism and cell state. Nature. 2017;543:681-686 pubmed publisher
  5. Lauritzen K, Hasan Olive M, Regnell C, Kleppa L, Scheibye Knudsen M, Gjedde A, et al. A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain. Neurobiol Aging. 2016;48:34-47 pubmed publisher
  6. Bal N, Maurya S, Singh S, Wehrens X, Periasamy M. Increased Reliance on Muscle-based Thermogenesis upon Acute Minimization of Brown Adipose Tissue Function. J Biol Chem. 2016;291:17247-57 pubmed publisher
  7. Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, et al. Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways. Autophagy. 2016;12:999-1014 pubmed publisher
  8. Korwitz A, Merkwirth C, Richter Dennerlein R, Tröder S, Sprenger H, Quirós P, et al. Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria. J Cell Biol. 2016;212:157-66 pubmed publisher
  9. Mukherjee R, Chakrabarti O. Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis. J Cell Sci. 2016;129:757-73 pubmed publisher
  10. Yu C, Liang J, Li J, Lee Y, Chang B, Su C, et al. Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins. PLoS Pathog. 2015;11:e1005350 pubmed publisher
  11. Sharoar M, Shi Q, Ge Y, He W, Hu X, Perry G, et al. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Mol Psychiatry. 2016;21:1263-71 pubmed publisher
  12. Fan S, Liu B, Sun L, Lv X, Lin Z, Chen W, et al. Mitochondrial fission determines cisplatin sensitivity in tongue squamous cell carcinoma through the BRCA1-miR-593-5p-MFF axis. Oncotarget. 2015;6:14885-904 pubmed
  13. Furuya N, Ikeda S, Sato S, Soma S, Ezaki J, Oliva Trejo J, et al. PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation. Autophagy. 2014;10:631-41 pubmed publisher
  14. Xu S, Pi H, Chen Y, Zhang N, Guo P, Lu Y, et al. Cadmium induced Drp1-dependent mitochondrial fragmentation by disturbing calcium homeostasis in its hepatotoxicity. Cell Death Dis. 2013;4:e540 pubmed publisher