This is a Validated Antibody Database (VAD) review about human FH, based on 4 published articles (read how Labome selects the articles), using FH antibody in all methods. It is aimed to help Labome visitors find the most suited FH antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FH synonym: FMRD; HLRCC; LRCC; MCL; MCUL1; fumarate hydratase, mitochondrial; fumarase

Knockout validation
Cell Signaling Technology
rabbit monoclonal (D9C5)
  • western blot knockout validation; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology FH antibody (Cell Signaling, 4567) was used in western blot knockout validation on human samples at 1:1000 (fig 2b). Mol Cell Biol (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (J-13)
  • immunohistochemistry - paraffin section; human; fig 1
Santa Cruz Biotechnology FH antibody (Santa Cruz Biotechnology, sc-100743) was used in immunohistochemistry - paraffin section on human samples (fig 1). Am J Surg Pathol (2016) ncbi
mouse monoclonal (J-13)
  • immunohistochemistry; human; 1:2000
Santa Cruz Biotechnology FH antibody (Santa Cruz Biotechnology, sc-100743) was used in immunohistochemistry on human samples at 1:2000. Virchows Arch (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D9C5)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology FH antibody (CST, 4567) was used in western blot on human samples (fig 5a). Oncotarget (2017) ncbi
rabbit monoclonal (D9C5)
  • western blot knockout validation; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology FH antibody (Cell Signaling, 4567) was used in western blot knockout validation on human samples at 1:1000 (fig 2b). Mol Cell Biol (2017) ncbi
Articles Reviewed
  1. Kitazawa S, Ebara S, Ando A, Baba Y, Satomi Y, Soga T, et al. Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors. Oncotarget. 2017;8:28922-28938 pubmed publisher
  2. Kerins M, Vashisht A, Liang B, Duckworth S, Praslicka B, WOHLSCHLEGEL J, et al. Fumarate Mediates a Chronic Proliferative Signal in Fumarate Hydratase-Inactivated Cancer Cells by Increasing Transcription and Translation of Ferritin Genes. Mol Cell Biol. 2017;37: pubmed publisher
  3. Harrison W, Andrici J, Maclean F, Madadi Ghahan R, Farzin M, Sioson L, et al. Fumarate Hydratase-deficient Uterine Leiomyomas Occur in Both the Syndromic and Sporadic Settings. Am J Surg Pathol. 2016;40:599-607 pubmed publisher
  4. Martínek P, Grossmann P, Hes O, Bouda J, Eret V, Frizzell N, et al. Genetic testing of leiomyoma tissue in women younger than 30 years old might provide an effective screening approach for the hereditary leiomyomatosis and renal cell cancer syndrome (HLRCC). Virchows Arch. 2015;467:185-91 pubmed publisher