This is a Validated Antibody Database (VAD) review about human FGR, based on 18 published articles (read how Labome selects the articles), using FGR antibody in all methods. It is aimed to help Labome visitors find the most suited FGR antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FGR synonym: SRC2; c-fgr; c-src2; p55-Fgr; p55c-fgr; p58-Fgr; p58c-fgr; tyrosine-protein kinase Fgr; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; c-fgr protooncogene; c-src-2 proto-oncogene; feline Gardner-Rasheed sarcoma viral oncogene homolog; p55-c-fgr protein; proto-oncogene c-Fgr; proto-oncogene tyrosine-protein kinase FGR; v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog

Santa Cruz Biotechnology
mouse monoclonal
  • western blot; human; 1:1000; loading ...; fig s9b
In order to examine whether p140Cap protein levels in ERBB2-amplified breast cancer patients correlate with survival, Santa Cruz Biotechnology FGR antibody (Santa Cruz, B-12) was used in western blot on human samples at 1:1000 (fig s9b). Nat Commun (2017) ncbi
mouse monoclonal (B-12)
  • western blot; human; 1:1000; loading ...; fig s9b
In order to examine whether p140Cap protein levels in ERBB2-amplified breast cancer patients correlate with survival, Santa Cruz Biotechnology FGR antibody (Santa Cruz, B-12) was used in western blot on human samples at 1:1000 (fig s9b). Nat Commun (2017) ncbi
mouse monoclonal (B-12)
  • western blot; rat; loading ...
In order to examine the impact of ischemia/reperfusion injury on sodium potassium ATPase enzymatic and signaling functions, Santa Cruz Biotechnology FGR antibody (Santa Cruz, Sc-8056) was used in western blot on rat samples . Physiol Rep (2016) ncbi
mouse monoclonal (B-12)
  • western blot; human; fig 2
In order to determine an enrichment in insulin-like growth factor I receptor, c-Src, G-protein-coupled receptor kinases, and focal adhesion kinase in porstate cancer cell exosomes, Santa Cruz Biotechnology FGR antibody (Santa Cruz, sc8056) was used in western blot on human samples (fig 2). J Cell Biochem (2017) ncbi
mouse monoclonal (B-12)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
  • immunoprecipitation; human; 1:50; fig 4
  • immunocytochemistry; human; 1:100; fig 4
  • western blot; human; 1:200; fig 1
In order to study improvement of the pathology of hypertrophic scar by simultaneous deactivation of FAK and Src, Santa Cruz Biotechnology FGR antibody (Santa Cruz Biotechnology, sc-8056) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1), in immunoprecipitation on human samples at 1:50 (fig 4), in immunocytochemistry on human samples at 1:100 (fig 4) and in western blot on human samples at 1:200 (fig 1). Sci Rep (2016) ncbi
mouse monoclonal (B-12)
  • western blot; human; 1:200; fig 1
Santa Cruz Biotechnology FGR antibody (Santa Cruz, sc-8056;) was used in western blot on human samples at 1:200 (fig 1). Int J Mol Med (2016) ncbi
mouse monoclonal (B-12)
  • western blot; rat; loading ...; fig 8a
Santa Cruz Biotechnology FGR antibody (Santa Cruz, sc8056) was used in western blot on rat samples (fig 8a). J Cell Mol Med (2016) ncbi
mouse monoclonal (B-12)
  • immunocytochemistry; mouse
In order to investigate the molecular mechanisms involved in TASK1 internalization in PC12 cells, Santa Cruz Biotechnology FGR antibody (Santa Cruz Biotechnology, sc-8056) was used in immunocytochemistry on mouse samples . Am J Physiol Cell Physiol (2015) ncbi
mouse monoclonal (B-12)
  • western blot; human
Santa Cruz Biotechnology FGR antibody (Santa Cruz, sc-8056) was used in western blot on human samples . Mol Cell Endocrinol (2015) ncbi
mouse monoclonal (B-12)
  • western blot; human; 1:1000; fig 5
Santa Cruz Biotechnology FGR antibody (Santa Cruz, sc-8056 B-12) was used in western blot on human samples at 1:1000 (fig 5). PLoS ONE (2015) ncbi
mouse monoclonal (B-12)
  • immunohistochemistry - paraffin section; human; 1:50
Santa Cruz Biotechnology FGR antibody (Santa Cruz, sc8056) was used in immunohistochemistry - paraffin section on human samples at 1:50. Exp Dermatol (2015) ncbi
mouse monoclonal (B-12)
  • immunocytochemistry; human; 1:50
  • western blot; human; 1:200
Santa Cruz Biotechnology FGR antibody (Santa Cruz, Sc-8056) was used in immunocytochemistry on human samples at 1:50 and in western blot on human samples at 1:200. Cell Signal (2015) ncbi
mouse monoclonal (B-12)
  • western blot; mouse; fig 8
Santa Cruz Biotechnology FGR antibody (Santa Cruz Biotechnology, sc-8056) was used in western blot on mouse samples (fig 8). J Neurosci (2015) ncbi
mouse monoclonal (B-12)
  • western blot; pig
In order to study the effect of ouabain on Src kinase and Na(+)/K(+)-ATPase, Santa Cruz Biotechnology FGR antibody (Santa Cruz Biotechnology, sc-8056) was used in western blot on pig samples . Biochem Biophys Res Commun (2014) ncbi
mouse monoclonal (B-12)
  • immunohistochemistry - paraffin section; human; 1:150
  • immunoprecipitation; human
  • western blot; human; 1:1000
Santa Cruz Biotechnology FGR antibody (Santa Cruz, sc-8056) was used in immunohistochemistry - paraffin section on human samples at 1:150, in immunoprecipitation on human samples and in western blot on human samples at 1:1000. Int J Cancer (2014) ncbi
mouse monoclonal (B-12)
  • western blot; human
Santa Cruz Biotechnology FGR antibody (Santa Cruz Biotechnology, sc-8056) was used in western blot on human samples . Eur J Cancer (2014) ncbi
mouse monoclonal (B-12)
  • western blot; mouse
Santa Cruz Biotechnology FGR antibody (Santa Cruz, sc-8056) was used in western blot on mouse samples . J Hepatol (2014) ncbi
ProMab
mouse monoclonal (#6G2)
  • western blot; mouse; fig 7
In order to determine the response threshold of immunoreceptor tyrosine-based activation motifs, ProMab FGR antibody (ProMab, 20318) was used in western blot on mouse samples (fig 7). elife (2015) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human
In order to study the molecular signaling responsible for retinoic acid-induced differentiation, Cell Signaling Technology FGR antibody (Cell Signaling, 2755) was used in western blot on human samples . PLoS ONE (2015) ncbi
Articles Reviewed
  1. Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, et al. The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries. Nat Commun. 2017;8:14797 pubmed publisher
  2. Belliard A, Gulati G, Duan Q, Alves R, Brewer S, Madan N, et al. Ischemia/reperfusion-induced alterations of enzymatic and signaling functions of the rat cardiac Na+/K+-ATPase: protection by ouabain preconditioning. Physiol Rep. 2016;4: pubmed
  3. DeRita R, Zerlanko B, Singh A, Lu H, Iozzo R, Benovic J, et al. c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes. J Cell Biochem. 2017;118:66-73 pubmed publisher
  4. Su L, Li X, Wu X, Hui B, Han S, Gao J, et al. Simultaneous deactivation of FAK and Src improves the pathology of hypertrophic scar. Sci Rep. 2016;6:26023 pubmed publisher
  5. Wu X, Yang L, Zheng Z, Li Z, Shi J, Li Y, et al. Src promotes cutaneous wound healing by regulating MMP-2 through the ERK pathway. Int J Mol Med. 2016;37:639-48 pubmed publisher
  6. Peng K, Tian X, Qian Y, Skibba M, Zou C, Liu Z, et al. Novel EGFR inhibitors attenuate cardiac hypertrophy induced by angiotensin II. J Cell Mol Med. 2016;20:482-94 pubmed publisher
  7. Freedman T, Tan Y, Skrzypczynska K, Manz B, Sjaastad F, Goodridge H, et al. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. elife. 2015;4: pubmed publisher
  8. Bunaciu R, Jensen H, Macdonald R, Latocha D, Varner J, Yen A. 6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells. PLoS ONE. 2015;10:e0135668 pubmed publisher
  9. Matsuoka H, Inoue M. Src mediates endocytosis of TWIK-related acid-sensitive K+ 1 channels in PC12 cells in response to nerve growth factor. Am J Physiol Cell Physiol. 2015;309:C251-63 pubmed publisher
  10. Chien P, Lin C, Hsiao L, Yang C. c-Src/Pyk2/EGFR/PI3K/Akt/CREB-activated pathway contributes to human cardiomyocyte hypertrophy: Role of COX-2 induction. Mol Cell Endocrinol. 2015;409:59-72 pubmed publisher
  11. Carnesecchi J, Malbouyres M, de Mets R, Balland M, Beauchef G, Vié K, et al. Estrogens induce rapid cytoskeleton re-organization in human dermal fibroblasts via the non-classical receptor GPR30. PLoS ONE. 2015;10:e0120672 pubmed publisher
  12. Choi C, Kim Y, Sohn J, Lee H, Kim W. Focal adhesion kinase and Src expression in premalignant and malignant skin lesions. Exp Dermatol. 2015;24:361-4 pubmed publisher
  13. Tamilzhalagan S, Muthuswami M, Periasamy J, Lee M, Rha S, Tan P, et al. Upregulated, 7q21-22 amplicon candidate gene SHFM1 confers oncogenic advantage by suppressing p53 function in gastric cancer. Cell Signal. 2015;27:1075-86 pubmed publisher
  14. Sheng L, Leshchyns ka I, Sytnyk V. Neural cell adhesion molecule 2 promotes the formation of filopodia and neurite branching by inducing submembrane increases in Ca2+ levels. J Neurosci. 2015;35:1739-52 pubmed publisher
  15. Gable M, Abdallah S, Najjar S, Liu L, Askari A. Digitalis-induced cell signaling by the sodium pump: on the relation of Src to Na(+)/K(+)-ATPase. Biochem Biophys Res Commun. 2014;446:1151-4 pubmed publisher
  16. Bouchekioua Bouzaghou K, Poulard C, Rambaud J, Lavergne E, Hussein N, Billaud M, et al. LKB1 when associated with methylatedER? is a marker of bad prognosis in breast cancer. Int J Cancer. 2014;135:1307-18 pubmed publisher
  17. Cao M, Hou D, Liang H, Gong F, Wang Y, Yan X, et al. miR-150 promotes the proliferation and migration of lung cancer cells by targeting SRC kinase signalling inhibitor 1. Eur J Cancer. 2014;50:1013-24 pubmed publisher
  18. Hou J, Xia Y, Jiang R, Chen D, Xu J, Deng L, et al. PTPRO plays a dual role in hepatic ischemia reperfusion injury through feedback activation of NF-?B. J Hepatol. 2014;60:306-12 pubmed publisher