This is a Validated Antibody Database (VAD) review about human FGFR4, based on 12 published articles (read how Labome selects the articles), using FGFR4 antibody in all methods. It is aimed to help Labome visitors find the most suited FGFR4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FGFR4 synonym: CD334; JTK2; TKF

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (A-10)
  • western blot knockout validation; human; loading ...; fig s1
Santa Cruz Biotechnology FGFR4 antibody (Santa Cruz Biotechnology, sc-136988) was used in western blot knockout validation on human samples (fig s1). Cancers (Basel) (2020) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D3B12)
  • western blot knockout validation; human; loading ...; fig 3b
Cell Signaling Technology FGFR4 antibody (CST, 8562) was used in western blot knockout validation on human samples (fig 3b). Theranostics (2021) ncbi
Abcam
mouse monoclonal (5B5)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1
Abcam FGFR4 antibody (Abcam, ab44971) was used in immunohistochemistry - frozen section on mouse samples (fig 2) and in immunohistochemistry - paraffin section on mouse samples (fig 1). Hepatol Commun (2022) ncbi
domestic rabbit monoclonal
  • western blot; human; 1:500; loading ...; fig 2k
Abcam FGFR4 antibody (Abcam, ab178396) was used in western blot on human samples at 1:500 (fig 2k). Aging (Albany NY) (2021) ncbi
mouse monoclonal (5B5)
  • flow cytometry; human; 1:100
  • immunocytochemistry; human; 1:100
Abcam FGFR4 antibody (Abcam, ab44971) was used in flow cytometry on human samples at 1:100 and in immunocytochemistry on human samples at 1:100. PLoS ONE (2013) ncbi
BioLegend
mouse monoclonal (4FR6D3)
  • flow cytometry; human; loading ...; fig 4b
BioLegend FGFR4 antibody (Biolegend, 4FR6D3) was used in flow cytometry on human samples (fig 4b). Mol Cancer Ther (2022) ncbi
mouse monoclonal (4FR6D3)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, BioLegend FGFR4 antibody (BioLegen d, 324306) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-10)
  • western blot knockout validation; human; loading ...; fig s1
Santa Cruz Biotechnology FGFR4 antibody (Santa Cruz Biotechnology, sc-136988) was used in western blot knockout validation on human samples (fig s1). Cancers (Basel) (2020) ncbi
mouse monoclonal (A-10)
  • western blot; human
Santa Cruz Biotechnology FGFR4 antibody (Santa Cruz, SC-136988) was used in western blot on human samples . J Thyroid Res (2014) ncbi
mouse monoclonal (A-10)
  • western blot; hamsters
Santa Cruz Biotechnology FGFR4 antibody (Santa Cruz, sc-136988) was used in western blot on hamsters samples . Protein Expr Purif (2014) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 8e
Invitrogen FGFR4 antibody (Invitrogen, PA5-105531) was used in western blot on mouse samples (fig 8e). Sci Rep (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D3B12)
  • western blot knockout validation; human; loading ...; fig 3b
Cell Signaling Technology FGFR4 antibody (CST, 8562) was used in western blot knockout validation on human samples (fig 3b). Theranostics (2021) ncbi
domestic rabbit monoclonal (D3B12)
  • western blot; human; loading ...; fig 5b
Cell Signaling Technology FGFR4 antibody (Cell Signalling, 8562) was used in western blot on human samples (fig 5b). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D3B12)
  • immunohistochemistry - frozen section; human; fig 3
  • western blot; human; fig 2
Cell Signaling Technology FGFR4 antibody (Cell Signalling, 8562) was used in immunohistochemistry - frozen section on human samples (fig 3) and in western blot on human samples (fig 2). Sci Rep (2015) ncbi
Articles Reviewed
  1. Sullivan P, Kumar R, Li W, Hoglund V, Wang L, Zhang Y, et al. FGFR4-Targeted Chimeric Antigen Receptors Combined with Anti-Myeloid Polypharmacy Effectively Treat Orthotopic Rhabdomyosarcoma. Mol Cancer Ther. 2022;21:1608-1621 pubmed publisher
  2. O Brien A, Zhou T, White T, Medford A, Chen L, Kyritsi K, et al. FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2-/- Mouse Model of Primary Sclerosing Cholangitis. Hepatol Commun. 2022;6:1574-1588 pubmed publisher
  3. Guo T, Gu C, Li B, Xu C. Dual inhibition of FGFR4 and BCL-xL inhibits multi-resistant ovarian cancer with BCL2L1 gain. Aging (Albany NY). 2021;13:19750-19759 pubmed publisher
  4. Homer Bouthiette C, Xiao L, Hurley M. Gait disturbances and muscle dysfunction in fibroblast growth factor 2 knockout mice. Sci Rep. 2021;11:11005 pubmed publisher
  5. Wang J, Zhao H, Zheng L, Zhou Y, Wu L, Xu Y, et al. FGF19/SOCE/NFATc2 signaling circuit facilitates the self-renewal of liver cancer stem cells. Theranostics. 2021;11:5045-5060 pubmed publisher
  6. Alijaj N, Moutel S, Gouveia Z, Gray M, Roveri M, Dzhumashev D, et al. Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma. Cancers (Basel). 2020;12: pubmed publisher
  7. Milkiewicz M, Klak M, Kempińska Podhorodecka A, Wiechowska Kozlowska A, Urasinska E, Blatkiewicz M, et al. Impaired Hepatic Adaptation to Chronic Cholestasis induced by Primary Sclerosing Cholangitis. Sci Rep. 2016;6:39573 pubmed publisher
  8. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  9. Wunsch E, Milkiewicz M, Wasik U, Trottier J, Kempińska Podhorodecka A, Elias E, et al. Expression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the disease. Sci Rep. 2015;5:13462 pubmed publisher
  10. Tohyama O, Matsui J, Kodama K, Hata Sugi N, Kimura T, Okamoto K, et al. Antitumor activity of lenvatinib (e7080): an angiogenesis inhibitor that targets multiple receptor tyrosine kinases in preclinical human thyroid cancer models. J Thyroid Res. 2014;2014:638747 pubmed publisher
  11. Sokolowska Wedzina A, Borek A, Chudzian J, Jakimowicz P, Zakrzewska M, Otlewski J. Efficient production and purification of extracellular domain of human FGFR-Fc fusion proteins from Chinese hamster ovary cells. Protein Expr Purif. 2014;99:50-7 pubmed publisher
  12. Zuliani T, Saiagh S, Knol A, Esbelin J, Dreno B. Fetal fibroblasts and keratinocytes with immunosuppressive properties for allogeneic cell-based wound therapy. PLoS ONE. 2013;8:e70408 pubmed publisher