This is a Validated Antibody Database (VAD) review about human FGFR3, based on 13 published articles (read how Labome selects the articles), using FGFR3 antibody in all methods. It is aimed to help Labome visitors find the most suited FGFR3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FGFR3 synonym: ACH; CD333; CEK2; HSFGFR3EX; JTK4; fibroblast growth factor receptor 3; FGFR-3; fibroblast growth factor receptor 3 variant 4; hydroxyaryl-protein kinase; tyrosine kinase JTK4

Santa Cruz Biotechnology
mouse monoclonal (B-9)
  • immunocytochemistry; human; 1:1000; loading ...; fig s10b
  • western blot; human; 1:1000; fig 2a
Santa Cruz Biotechnology FGFR3 antibody (Santa Cruz, sc-13121) was used in immunocytochemistry on human samples at 1:1000 (fig s10b) and in western blot on human samples at 1:1000 (fig 2a). Nature (2018) ncbi
mouse monoclonal (B-9)
  • immunohistochemistry - paraffin section; human; fig 1
Santa Cruz Biotechnology FGFR3 antibody (Santa Cruz, SC-3121) was used in immunohistochemistry - paraffin section on human samples (fig 1). Cancer Med (2016) ncbi
mouse monoclonal (B-9)
  • immunohistochemistry - paraffin section; human; 1:50; tbl 1
Santa Cruz Biotechnology FGFR3 antibody (Santa Cruz Biotechnology, SC-13121) was used in immunohistochemistry - paraffin section on human samples at 1:50 (tbl 1). Cancer Res Treat (2016) ncbi
mouse monoclonal (B-9)
  • immunohistochemistry; human; 1:50
Santa Cruz Biotechnology FGFR3 antibody (Santa Cruz, B-9) was used in immunohistochemistry on human samples at 1:50. Appl Immunohistochem Mol Morphol (2015) ncbi
mouse monoclonal (B-9)
  • immunohistochemistry; human; 1:25
Santa Cruz Biotechnology FGFR3 antibody (Santa Cruz, sc-13121) was used in immunohistochemistry on human samples at 1:25. Hum Reprod (2013) ncbi
R&D Systems
mouse monoclonal (136334)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, R&D Systems FGFR3 antibody (R&D Systems, FAB766P) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
OriGene
mouse monoclonal (OTI1B10)
  • immunohistochemistry; human; 1:200
  • western blot; human; 1:400
OriGene FGFR3 antibody (Origene, TA801078) was used in immunohistochemistry on human samples at 1:200 and in western blot on human samples at 1:400. Mol Cell Endocrinol (2015) ncbi
Abcam
rabbit polyclonal
  • immunocytochemistry; mouse; 1:1000
Abcam FGFR3 antibody (Abcam, ab10651) was used in immunocytochemistry on mouse samples at 1:1000. PLoS ONE (2014) ncbi
MilliporeSigma
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 2f
MilliporeSigma FGFR3 antibody (Sigma, F0425) was used in western blot on human samples at 1:2000 (fig 2f). Dis Model Mech (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:600; fig 4
In order to develop and characterize patient-derived primary xenografts to a model of muscle invasive bladder cancer, MilliporeSigma FGFR3 antibody (Sigma-Aldrich, F0425) was used in immunohistochemistry - paraffin section on human samples at 1:600 (fig 4). Oncotarget (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (C51F2)
  • immunohistochemistry; human; fig 6a
  • western blot; human; fig 4a
Cell Signaling Technology FGFR3 antibody (Cell Signaling, C51F2) was used in immunohistochemistry on human samples (fig 6a) and in western blot on human samples (fig 4a). Oncotarget (2015) ncbi
rabbit monoclonal (C51F2)
  • western blot; human
Cell Signaling Technology FGFR3 antibody (Cell Signaling, 4574) was used in western blot on human samples . J Thyroid Res (2014) ncbi
rabbit monoclonal (C51F2)
  • western blot; human
In order to study mechanism of resistance to the FGFR inhibitor BGJ398 and the FGFR inhibitor ponatinib, Cell Signaling Technology FGFR3 antibody (cell signaling, 4574S) was used in western blot on human samples . Oncogene (2015) ncbi
Articles Reviewed
  1. Frattini V, Pagnotta S, Tala -, Fan J, Russo M, Lee S, et al. A metabolic function of FGFR3-TACC3 gene fusions in cancer. Nature. 2018;553:222-227 pubmed publisher
  2. Yin Y, Ren X, Smith C, Guo Q, Malabunga M, Guernah I, et al. Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody. Dis Model Mech. 2016;9:563-71 pubmed publisher
  3. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  4. Koole K, van Kempen P, Swartz J, Peeters T, van Diest P, Koole R, et al. Fibroblast growth factor receptor 3 protein is overexpressed in oral and oropharyngeal squamous cell carcinoma. Cancer Med. 2016;5:275-84 pubmed publisher
  5. Inaguma S, Ito H, Riku M, Ikeda H, Kasai K. Addiction of pancreatic cancer cells to zinc-finger transcription factor ZIC2. Oncotarget. 2015;6:28257-68 pubmed publisher
  6. Park S, Nam S, Keam B, Kim T, Jeon Y, Lee S, et al. VEGF and Ki-67 Overexpression in Predicting Poor Overall Survival in Adenoid Cystic Carcinoma. Cancer Res Treat. 2016;48:518-26 pubmed publisher
  7. Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt A, et al. Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies. Oncotarget. 2015;6:21522-32 pubmed
  8. Tohyama O, Matsui J, Kodama K, Hata Sugi N, Kimura T, Okamoto K, et al. Antitumor activity of lenvatinib (e7080): an angiogenesis inhibitor that targets multiple receptor tyrosine kinases in preclinical human thyroid cancer models. J Thyroid Res. 2014;2014:638747 pubmed publisher
  9. Mansoor A, Akhter A, Pournazari P, Mahe E, Shariff S, Farooq F, et al. Protein Expression for Novel Prognostic Markers (Cyclins D1, D2, D3, B1, B2, ITGβ7, FGFR3, PAX5) Correlate With Previously Reported Gene Expression Profile Patterns in Plasma Cell Myeloma. Appl Immunohistochem Mol Morphol. 2015;23:327-33 pubmed publisher
  10. Winge S, Nielsen J, Jørgensen A, Owczarek S, Ewen K, Nielsen J, et al. Biglycan is a novel binding partner of fibroblast growth factor receptor 3c (FGFR3c) in the human testis. Mol Cell Endocrinol. 2015;399:235-43 pubmed publisher
  11. Wang J, Mikse O, Liao R, Li Y, Tan L, Jänne P, et al. Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells. Oncogene. 2015;34:2167-77 pubmed publisher
  12. Liu D, Huang X, Guo X, Meng X, Wu Y, Lu H, et al. Voltage dependent potassium channel remodeling in murine intestinal smooth muscle hypertrophy induced by partial obstruction. PLoS ONE. 2014;9:e86109 pubmed publisher
  13. Kossack N, Terwort N, Wistuba J, Ehmcke J, Schlatt S, Scholer H, et al. A combined approach facilitates the reliable detection of human spermatogonia in vitro. Hum Reprod. 2013;28:3012-25 pubmed publisher