This is a Validated Antibody Database (VAD) review about
human FEN1, based on 12 published articles (
read how Labome selects the articles), using FEN1 antibody in all methods. It is aimed to help Labome visitors find the most suited FEN1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FEN1 synonym: FEN-1; MF1; RAD2; flap endonuclease 1; DNase IV; maturation factor-1
GeneTex
| mouse monoclonal (4E7) | - immunohistochemistry - paraffin section; human; loading ...; fig 1b
- western blot; human; loading ...; fig 2a
| In order to show that flap endonuclease 1 is critical for the rapid proliferation of lung cancer cells, GeneTex FEN1 antibody (Gentex, 70185) was used in immunohistochemistry - paraffin section on human samples (fig 1b) and in western blot on human samples (fig 2a). Mol Oncol (2017) ncbi |
| mouse monoclonal (4E7) | - immunoprecipitation; human; loading ...; fig 5a
- western blot; human; loading ...; fig 5a
| GeneTex FEN1 antibody (GeneTex, GTX70185) was used in immunoprecipitation on human samples (fig 5a) and in western blot on human samples (fig 5a). EMBO J (2015) ncbi |
| mouse monoclonal (4E7) | | GeneTex FEN1 antibody (Genetex, GTX70185) was used in western blot on human samples . Mol Cell Biol (2008) ncbi |
| mouse monoclonal (4E7) | | GeneTex FEN1 antibody (Genetex, GTX70185) was used in western blot on human samples . Mol Cell Biol (2008) ncbi |
| mouse monoclonal (4E7) | | GeneTex FEN1 antibody (Genetex Company, GTX70185) was used in western blot on human samples . J Mol Biol (2008) ncbi |
Abcam
| rabbit monoclonal (EPR4460(2)) | - western blot; human; 1:5000; loading ...; fig 5n
| Abcam FEN1 antibody (Abcam, AB109132) was used in western blot on human samples at 1:5000 (fig 5n). Aging (Albany NY) (2018) ncbi |
Santa Cruz Biotechnology
| mouse monoclonal (4E7) | - western blot; human; loading ...; fig s3
| Santa Cruz Biotechnology FEN1 antibody (SantaCruz, sc-56675) was used in western blot on human samples (fig s3). Oncogene (2017) ncbi |
Bethyl
| rabbit polyclonal | - western blot; human; loading ...; fig 1
| Bethyl FEN1 antibody (Bethyl Laboratories, A300-256) was used in western blot on human samples (fig 1). Nucleic Acids Res (2017) ncbi |
| rabbit polyclonal | - western blot; human; fig 2
| Bethyl FEN1 antibody (Bethyl, A300-255A) was used in western blot on human samples (fig 2). J Biol Chem (2015) ncbi |
| rabbit polyclonal | - immunoprecipitation; human; fig 1
- western blot; human; fig 1
| Bethyl FEN1 antibody (Bethyl Lab, A300-255A) was used in immunoprecipitation on human samples (fig 1) and in western blot on human samples (fig 1). Biochem J (2015) ncbi |
Cell Signaling Technology
| rabbit polyclonal | - western blot; human; loading ...; fig 7b
| Cell Signaling Technology FEN1 antibody (Cell Signaling, 2746) was used in western blot on human samples (fig 7b). Oncol Rep (2016) ncbi |
| rabbit polyclonal | - western blot; human; loading ...; fig 6c
| In order to study quinacrine-induced apoptosis, Cell Signaling Technology FEN1 antibody (Cell Signaling, 2746) was used in western blot on human samples (fig 6c). Biochem Pharmacol (2016) ncbi |
Ma S, Yang D, Liu Y, Wang Y, Lin T, Li Y,
et al. LncRNA BANCR promotes tumorigenesis and enhances adriamycin resistance in colorectal cancer. Aging (Albany NY). 2018;10:2062-2078
pubmed publisher Bj Rås K, Sousa M, Sharma A, Fonseca D, S Gaard C, Bj Rås M,
et al. Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication. Nucleic Acids Res. 2017;45:8291-8301
pubmed publisher He L, Luo L, Zhu H, Yang H, Zhang Y, Wu H,
et al. FEN1 promotes tumor progression and confers cisplatin resistance in non-small-cell lung cancer. Mol Oncol. 2017;11:640-654
pubmed publisher Sun H, He L, Wu H, Pan F, Wu X, Zhao J,
et al. The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation. Oncogene. 2017;36:194-207
pubmed publisher Sumiyoshi H, Matsushita A, Nakamura Y, Matsuda Y, Ishiwata T, Naito Z,
et al. Suppression of STAT5b in pancreatic cancer cells leads to attenuated gemcitabine chemoresistance, adhesion and invasion. Oncol Rep. 2016;35:3216-26
pubmed publisher Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D,
et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33
pubmed publisher Teasley D, Parajuli S, Nguyen M, Moore H, Alspach E, Lock Y,
et al. Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand. J Biol Chem. 2015;290:15133-45
pubmed publisher Liu S, Lu G, Ali S, Liu W, Zheng L, Dai H,
et al. Okazaki fragment maturation involves α-segment error editing by the mammalian FEN1/MutSα functional complex. EMBO J. 2015;34:1829-43
pubmed publisher Sami F, Lu X, Parvathaneni S, Roy R, Gary R, Sharma S. RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin. Biochem J. 2015;468:227-44
pubmed publisher Liu P, Qian L, Sung J, de Souza Pinto N, Zheng L, Bogenhagen D,
et al. Removal of oxidative DNA damage via FEN1-dependent long-patch base excision repair in human cell mitochondria. Mol Cell Biol. 2008;28:4975-87
pubmed publisher Guo Z, Qian L, Liu R, Dai H, Zhou M, Zheng L,
et al. Nucleolar localization and dynamic roles of flap endonuclease 1 in ribosomal DNA replication and damage repair. Mol Cell Biol. 2008;28:4310-9
pubmed publisher Guo Z, Chavez V, Singh P, Finger L, Hang H, Hegde M,
et al. Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways. J Mol Biol. 2008;377:679-90
pubmed publisher
- If you are aware of any publication with knockout studies validating a monoclonal or recombinant antibody, either purchased from a supplier or developed by the author(s), please notify us through feedback.
