This is a Validated Antibody Database (VAD) review about human FBXW7, based on 13 published articles (read how Labome selects the articles), using FBXW7 antibody in all methods. It is aimed to help Labome visitors find the most suited FBXW7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FBXW7 synonym: AGO; CDC4; FBW6; FBW7; FBX30; FBXO30; FBXW6; SEL-10; SEL10; hAgo; hCdc4

Abcam
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5h
  • western blot; human; 1:1000; loading ...; fig 5h
Abcam FBXW7 antibody (Abcam, ab109617) was used in western blot on mouse samples at 1:1000 (fig 5h) and in western blot on human samples at 1:1000 (fig 5h). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4d
Abcam FBXW7 antibody (Abcam, ab109617) was used in western blot on human samples (fig 4d). Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (SP237)
  • western blot; human; 1:1000; loading ...; fig 6a
Abcam FBXW7 antibody (Abcam, ab227677) was used in western blot on human samples at 1:1000 (fig 6a). Biosci Rep (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:1000; loading ...; fig 6a
Abcam FBXW7 antibody (Abcam, ab109617) was used in immunohistochemistry on human samples at 1:1000 (fig 6a). Oncogenesis (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s2a
Abcam FBXW7 antibody (Abcam, Ab109617) was used in western blot on human samples (fig s2a). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 4e
Abcam FBXW7 antibody (Abcam, ab109617) was used in western blot on mouse samples (fig 4e). J Cell Biol (2017) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s5b
Invitrogen FBXW7 antibody (Invitrogen, 40-1500) was used in western blot on human samples (fig s5b). J Clin Invest (2018) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:3000; loading ...; fig 3f
In order to describe the mechanism by which FBXW7 stabilizes RigI, Invitrogen FBXW7 antibody (Thermo Fisher, 40-1500) was used in immunocytochemistry on human samples at 1:3000 (fig 3f). Nat Commun (2017) ncbi
OriGene
mouse monoclonal (OTI6F5)
  • immunohistochemistry - paraffin section; human; 1:150; loading ...; fig 1
OriGene FBXW7 antibody (OriGene Technologies, TA802869) was used in immunohistochemistry - paraffin section on human samples at 1:150 (fig 1). Int J Oncol (2015) ncbi
Abnova
mouse monoclonal (3D1)
  • immunoprecipitation; mouse; 1:1000; fig 1d
Abnova FBXW7 antibody (Abnova, H00055294-M02) was used in immunoprecipitation on mouse samples at 1:1000 (fig 1d). EMBO J (2015) ncbi
Diagenode
monoclonal
  • RNA immunoprecipitation; human; loading ...; fig 6a
Diagenode FBXW7 antibody (Diagenode, C15200167) was used in RNA immunoprecipitation on human samples (fig 6a). Nucleic Acids Res (2018) ncbi
MilliporeSigma
mouse monoclonal (3D1)
  • western blot; human; fig 1
MilliporeSigma FBXW7 antibody (Sigma, WH0055294M2) was used in western blot on human samples (fig 1). Int J Mol Sci (2015) ncbi
mouse monoclonal (3D1)
  • immunohistochemistry - paraffin section; human; 1:100
  • western blot; human; 1:1000; fig 6
In order to discuss the anti-tumor effects of Fbxw7 in HCC and the clinical significance, MilliporeSigma FBXW7 antibody (Sigma, WH0055294M2) was used in immunohistochemistry - paraffin section on human samples at 1:100 and in western blot on human samples at 1:1000 (fig 6). Mol Cancer (2014) ncbi
Articles Reviewed
  1. Liu L, Tao T, Liu S, Yang X, Chen X, Liang J, et al. An RFC4/Notch1 signaling feedback loop promotes NSCLC metastasis and stemness. Nat Commun. 2021;12:2693 pubmed publisher
  2. Huang Y, Cai K, Xu P, Wang L, Huang C, Fang Y, et al. CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis. Signal Transduct Target Ther. 2021;6:10 pubmed publisher
  3. Guo Y, Zhang Z, Wang Z, Liu G, Liu Y, Wang H. Astragalus polysaccharides inhibit ovarian cancer cell growth via microRNA-27a/FBXW7 signaling pathway. Biosci Rep. 2020;40: pubmed publisher
  4. Ailiken G, Kitamura K, Hoshino T, Satoh M, Tanaka N, Minamoto T, et al. Post-transcriptional regulation of BRG1 by FIRΔexon2 in gastric cancer. Oncogenesis. 2020;9:26 pubmed publisher
  5. Bonath F, Domingo Prim J, Tarbier M, Friedländer M, Visa N. Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks. Nucleic Acids Res. 2018;46:11869-11882 pubmed publisher
  6. Li L, Guturi K, Gautreau B, Patel P, Saad A, Morii M, et al. Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis. J Clin Invest. 2018;128:4525-4542 pubmed publisher
  7. Song Y, Lai L, Chong Z, He J, Zhang Y, Xue Y, et al. E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses. Nat Commun. 2017;8:14654 pubmed publisher
  8. Gómez Pastor R, Burchfiel E, Neef D, Jaeger A, Cabiscol E, McKinstry S, et al. Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease. Nat Commun. 2017;8:14405 pubmed publisher
  9. Wakatsuki S, Tokunaga S, Shibata M, Araki T. GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration. J Cell Biol. 2017;216:477-493 pubmed publisher
  10. Maskey D, Marlin M, Kim S, Kim S, Ong E, Li G, et al. Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length. EMBO J. 2015;34:2424-40 pubmed publisher
  11. Wang X, Zhang J, Zhou L, Sun W, Zheng Z, Lu P, et al. Fbxw7 regulates hepatocellular carcinoma migration and invasion via Notch1 signaling pathway. Int J Oncol. 2015;47:231-43 pubmed publisher
  12. Li Z, Xiao J, Hu K, Wang G, Li M, Zhang J, et al. FBXW7 acts as an independent prognostic marker and inhibits tumor growth in human osteosarcoma. Int J Mol Sci. 2015;16:2294-306 pubmed publisher
  13. Tu K, Yang W, Li C, Zheng X, Lu Z, Guo C, et al. Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma. Mol Cancer. 2014;13:110 pubmed publisher