This is a Validated Antibody Database (VAD) review about human FAP, based on 21 published articles (read how Labome selects the articles), using FAP antibody in all methods. It is aimed to help Labome visitors find the most suited FAP antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FAP synonym: DPPIV; FAPA; FAPalpha; SIMP

Abcam
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig s5
Abcam FAP antibody (Abcam, ab53066) was used in immunocytochemistry on human samples (fig s5). Front Cell Dev Biol (2021) ncbi
domestic rabbit monoclonal (EPR20021)
  • immunohistochemistry - paraffin section; human; loading ...; fig 2b
  • immunohistochemistry - paraffin section; mouse; loading ...; fig e3a
Abcam FAP antibody (Abcam, ab207178) was used in immunohistochemistry - paraffin section on human samples (fig 2b) and in immunohistochemistry - paraffin section on mouse samples (fig e3a). Nature (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4a
Abcam FAP antibody (Abcam, ab28244) was used in western blot on human samples (fig 4a). J Exp Med (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig 3
  • immunocytochemistry; mouse; loading ...; fig 6a
Abcam FAP antibody (Abcam, ab28244) was used in immunohistochemistry - frozen section on mouse samples (fig 3) and in immunocytochemistry on mouse samples (fig 6a). Wound Repair Regen (2018) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 2a
In order to test if metastasis can be reduced by targeting cancer-associated fibroblasts with Pirfenidone, Abcam FAP antibody (Abcam, ab53066) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 2a). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; fig 5
Abcam FAP antibody (Abcam, ab28244) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 5). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:100; fig s15
  • western blot; human; 1:500; fig 3
  • immunohistochemistry - frozen section; mouse; 1:100; fig 2
Abcam FAP antibody (Abcam, ab53066) was used in immunocytochemistry on human samples at 1:100 (fig s15), in western blot on human samples at 1:500 (fig 3) and in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 2). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; fig s2
In order to propose that epithelial tension and matricellular fibrosis contribute to the aggressiveness of SMAD4 mutant pancreatic tumors, Abcam FAP antibody (Abcam, AB53066) was used in immunohistochemistry on mouse samples at 1:500 (fig s2). Nat Med (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:300; fig 2
  • western blot; mouse; 1:500; fig 3
Abcam FAP antibody (Abcam, ab28244) was used in immunohistochemistry - frozen section on mouse samples at 1:300 (fig 2) and in western blot on mouse samples at 1:500 (fig 3). Mol Med Rep (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:100; fig s6b
Abcam FAP antibody (Abcam, ab28244) was used in immunocytochemistry on mouse samples at 1:100 (fig s6b). Nat Commun (2016) ncbi
Invitrogen
mouse monoclonal (F11-24)
  • immunohistochemistry - frozen section; human; loading ...; fig 1a
Invitrogen FAP antibody (eBioscience, F11-24) was used in immunohistochemistry - frozen section on human samples (fig 1a). Nature (2019) ncbi
mouse monoclonal (F11-24)
  • western blot; human; loading ...; fig 3a
In order to examine the mechanisms by which IL-6/STAT3 signaling and TIMP-1 modulate the crosstalk between tumor cells and cancer associated fibroblasts in the tumor microenvironment, Invitrogen FAP antibody (eBiosciences, BMS168) was used in western blot on human samples (fig 3a). Cell Signal (2016) ncbi
mouse monoclonal (F11-24)
  • immunocytochemistry; human; fig s1
In order to study the role of MAPK-microRNA in the interaction between cancer cells and neighboring fibroblasts, Invitrogen FAP antibody (eBioscience, BMS168) was used in immunocytochemistry on human samples (fig s1). Cancer Biol Ther (2015) ncbi
mouse monoclonal (F11-24)
  • immunohistochemistry; human; 1:400; tbl s4
In order to study the involvement of COX/mPGES-1/PGE2 pathway in tumor inflammatory environment, Invitrogen FAP antibody (eBioscience, BMS168) was used in immunohistochemistry on human samples at 1:400 (tbl s4). Proc Natl Acad Sci U S A (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F11-24)
  • immunohistochemistry - frozen section; human; loading ...; fig 1i
Santa Cruz Biotechnology FAP antibody (Santa Cruz, sc-65398) was used in immunohistochemistry - frozen section on human samples (fig 1i). Oncogene (2019) ncbi
mouse monoclonal (F11-24)
  • immunocytochemistry; human; fig 8
  • western blot; human; fig 4
Santa Cruz Biotechnology FAP antibody (santa Cruz, sc-65398) was used in immunocytochemistry on human samples (fig 8) and in western blot on human samples (fig 4). Oncotarget (2015) ncbi
mouse monoclonal (SS-13)
  • immunocytochemistry; human
  • western blot; human
Santa Cruz Biotechnology FAP antibody (Santa-Cruz Biotechnologies, sc-100528) was used in immunocytochemistry on human samples and in western blot on human samples . BMC Cell Biol (2014) ncbi
R&D Systems
domestic sheep polyclonal
  • western blot; human; 1:2000; fig s5
R&D Systems FAP antibody (R&D Systems, AF3715) was used in western blot on human samples at 1:2000 (fig s5). J Exp Clin Cancer Res (2021) ncbi
domestic sheep polyclonal
  • western blot; human; 1:2000; fig s5
R&D Systems FAP antibody (R&D Systems, AF3715) was used in western blot on human samples at 1:2000 (fig s5). Schizophr Bull (2021) ncbi
domestic sheep polyclonal
  • western blot; human; loading ...; fig 1a
R&D Systems FAP antibody (R&D Systems, AF3715) was used in western blot on human samples (fig 1a). Cancers (Basel) (2021) ncbi
Abnova
mouse monoclonal (1.00E+05)
  • western blot; human; fig 2A
Abnova FAP antibody (Abnova, H00002191-M01) was used in western blot on human samples (fig 2A). Prostate (2014) ncbi
MilliporeSigma
mouse monoclonal (100000)
  • western blot; human; loading ...; fig 5c
MilliporeSigma FAP antibody (Sigma-Aldrich, WH0002191M1) was used in western blot on human samples (fig 5c). Breast Cancer Res (2019) ncbi
Articles Reviewed
  1. Zhang J, Qi J, Wei H, Lei Y, Yu H, Liu N, et al. TGFβ1 in Cancer-Associated Fibroblasts Is Associated With Progression and Radiosensitivity in Small-Cell Lung Cancer. Front Cell Dev Biol. 2021;9:667645 pubmed publisher
  2. Ray U, Roy D, Jin L, Thirusangu P, Staub J, Xiao Y, et al. Group III phospholipase A2 downregulation attenuated survival and metastasis in ovarian cancer and promotes chemo-sensitization. J Exp Clin Cancer Res. 2021;40:182 pubmed publisher
  3. Dwir D, Cabungcal J, Xin L, Giangreco B, Parietti E, Cleusix M, et al. Timely N-Acetyl-Cysteine and Environmental Enrichment Rescue Oxidative Stress-Induced Parvalbumin Interneuron Impairments via MMP9/RAGE Pathway: A Translational Approach for Early Intervention in Psychosis. Schizophr Bull. 2021;47:1782-1794 pubmed publisher
  4. Ganig N, Baenke F, Thepkaysone M, Lin K, Rao V, Wong F, et al. Proteomic Analyses of Fibroblast- and Serum-Derived Exosomes Identify QSOX1 as a Marker for Non-invasive Detection of Colorectal Cancer. Cancers (Basel). 2021;13: pubmed publisher
  5. Zhou Q, Wu X, Wang X, Yu Z, Pan T, Li Z, et al. The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis. Oncogene. 2019;: pubmed publisher
  6. Ren J, Smid M, Iaria J, Salvatori D, van Dam H, Zhu H, et al. Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression. Breast Cancer Res. 2019;21:109 pubmed publisher
  7. Aghajanian H, Kimura T, Rurik J, Hancock A, Leibowitz M, Li L, et al. Targeting cardiac fibrosis with engineered T cells. Nature. 2019;573:430-433 pubmed publisher
  8. Croft A, Campos J, Jansen K, Turner J, Marshall J, Attar M, et al. Distinct fibroblast subsets drive inflammation and damage in arthritis. Nature. 2019;570:246-251 pubmed publisher
  9. Gao Q, Yang Z, Xu S, Li X, Yang X, Jin P, et al. Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer. J Exp Med. 2019;216:688-703 pubmed publisher
  10. Xu K, Pan X, Qiu X, Wang D, Dong N, Yang L, et al. Neural crest-derived cells migrate from nerve to participate in Achilles tendon remodeling. Wound Repair Regen. 2018;26:54-63 pubmed publisher
  11. Takai K, Le A, Weaver V, Werb Z. Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer. Oncotarget. 2016;7:82889-82901 pubmed publisher
  12. Evrard S, Lecce L, Michelis K, Nomura Kitabayashi A, Pandey G, Purushothaman K, et al. Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability. Nat Commun. 2016;7:11853 pubmed publisher
  13. Zheng X, Xu M, Yao B, Wang C, Jia Y, Liu Q. IL-6/STAT3 axis initiated CAFs via up-regulating TIMP-1 which was attenuated by acetylation of STAT3 induced by PCAF in HCC microenvironment. Cell Signal. 2016;28:1314-24 pubmed publisher
  14. Laklai H, Miroshnikova Y, Pickup M, Collisson E, Kim G, Barrett A, et al. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med. 2016;22:497-505 pubmed publisher
  15. Li M, Li M, Yin T, Shi H, Wen Y, Zhang B, et al. Targeting of cancer‑associated fibroblasts enhances the efficacy of cancer chemotherapy by regulating the tumor microenvironment. Mol Med Rep. 2016;13:2476-84 pubmed publisher
  16. Avgustinova A, Iravani M, Robertson D, Fearns A, Gao Q, Klingbeil P, et al. Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness. Nat Commun. 2016;7:10305 pubmed publisher
  17. Doldi V, Callari M, Giannoni E, D Aiuto F, Maffezzini M, Valdagni R, et al. Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation. Oncotarget. 2015;6:31441-60 pubmed publisher
  18. Shah S, Miller P, Garcia Contreras M, Ao Z, Machlin L, Issa E, et al. Hierarchical paracrine interaction of breast cancer associated fibroblasts with cancer cells via hMAPK-microRNAs to drive ER-negative breast cancer phenotype. Cancer Biol Ther. 2015;16:1671-81 pubmed publisher
  19. Larsson K, Kock A, Idborg H, Arsenian Henriksson M, Martinsson T, Johnsen J, et al. COX/mPGES-1/PGE2 pathway depicts an inflammatory-dependent high-risk neuroblastoma subset. Proc Natl Acad Sci U S A. 2015;112:8070-5 pubmed publisher
  20. Jia J, Martin T, Ye L, Jiang W. FAP-? (Fibroblast activation protein-?) is involved in the control of human breast cancer cell line growth and motility via the FAK pathway. BMC Cell Biol. 2014;15:16 pubmed publisher
  21. Bohonowych J, Hance M, Nolan K, DEFEE M, Parsons C, Isaacs J. Extracellular Hsp90 mediates an NF-?B dependent inflammatory stromal program: implications for the prostate tumor microenvironment. Prostate. 2014;74:395-407 pubmed publisher