This is a Validated Antibody Database (VAD) review about human EphB4, based on 13 published articles (read how Labome selects the articles), using EphB4 antibody in all methods. It is aimed to help Labome visitors find the most suited EphB4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
EphB4 synonym: CMAVM2; HFASD; HTK; LMPHM7; MYK1; TYRO11

Invitrogen
mouse monoclonal (3D7G8)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
In order to examine if EphA2 and EphB4 proteins are suitable targets for image-guided oncologic surgery of colorectal cancer, Invitrogen EphB4 antibody (Life Technologies, 37-1800) was used in immunohistochemistry - paraffin section on human samples (fig 1a). Int J Mol Sci (2017) ncbi
mouse monoclonal (3D7G8)
  • immunoprecipitation; human; fig 4
In order to elucidate how YES contributes to colorectal cancer progression, Invitrogen EphB4 antibody (Biosource, 3D7G8) was used in immunoprecipitation on human samples (fig 4). Am J Cancer Res (2015) ncbi
mouse monoclonal (3D7G8)
  • western blot; human; 1:500
In order to study the role of ABC transporter subfamily C member 10 plays in paclitaxel-induced resistance to chemotherapy, Invitrogen EphB4 antibody (Life technologies, 3D7G8) was used in western blot on human samples at 1:500. Oncotarget (2015) ncbi
mouse monoclonal (3D7G8)
  • western blot; human; 1:200
Invitrogen EphB4 antibody (Zymed Laboratories, 3D7G8) was used in western blot on human samples at 1:200. Tumour Biol (2014) ncbi
mouse monoclonal (3D7G8)
  • immunohistochemistry - paraffin section; human; 1:50
Invitrogen EphB4 antibody (Invitrogen, 3D7G8) was used in immunohistochemistry - paraffin section on human samples at 1:50. Ann Diagn Pathol (2014) ncbi
mouse monoclonal (3D7G8)
  • immunohistochemistry - paraffin section; human; 10 ug/ml; fig 2
In order to investigate the prognostic value of EPHB4 in colorectal cancer therapy, Invitrogen EphB4 antibody (EPHB4, 37-1,800) was used in immunohistochemistry - paraffin section on human samples at 10 ug/ml (fig 2). Med Oncol (2013) ncbi
mouse monoclonal (3D7F8)
  • western blot; human; fig 1
In order to investigate the epigenetic silencing of Wnt/beta-catenin targets during colorectal tumorigenesis, Invitrogen EphB4 antibody (Invitrogen, 35-2900) was used in western blot on human samples (fig 1). Epigenetics (2011) ncbi
mouse monoclonal (3D7G8)
  • immunohistochemistry - paraffin section; human; fig 1
  • western blot; human; 1:200; fig 3
In order to study the role of EPHB4 in colorectal cancer and determine its value as a prognostic marker, Invitrogen EphB4 antibody (Zymed, 3D7G8) was used in immunohistochemistry - paraffin section on human samples (fig 1) and in western blot on human samples at 1:200 (fig 3). Cancer Res (2006) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; 1:50; fig 4
  • immunocytochemistry; rat; 1:50; fig 4
Abcam EphB4 antibody (Abcam, ab76657) was used in immunohistochemistry - paraffin section on rat samples at 1:50 (fig 4) and in immunocytochemistry on rat samples at 1:50 (fig 4). Physiol Rep (2016) ncbi
rat monoclonal (RM0056-6A14)
  • proximity ligation assay; mouse; fig 3
Abcam EphB4 antibody (abcam, ab73259) was used in proximity ligation assay on mouse samples (fig 3). Sci Rep (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (5G2F8)
  • western blot; mouse; fig 3d
Santa Cruz Biotechnology EphB4 antibody (santa cruz, sc-130081) was used in western blot on mouse samples (fig 3d). Int J Mol Med (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D1C7N)
  • immunohistochemistry - paraffin section; human; loading ...; fig 6a
Cell Signaling Technology EphB4 antibody (Cell Signaling, 14960) was used in immunohistochemistry - paraffin section on human samples (fig 6a). Cancer Res (2021) ncbi
domestic rabbit monoclonal (D1C7N)
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 3c
Cell Signaling Technology EphB4 antibody (Cell signaling, D1C7 N) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 3c). Histochem Cell Biol (2017) ncbi
Articles Reviewed
  1. Davenport M, Echols J, Silva A, Anderson J, Owens P, Yates C, et al. miR-31 displays subtype specificity in lung cancer. Cancer Res. 2021;: pubmed publisher
  2. Stammes M, Prevoo H, Ter Horst M, Groot S, Van De Velde C, Chan A, et al. Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery. Int J Mol Sci. 2017;18: pubmed publisher
  3. Moser G, Weiss G, Sundl M, Gauster M, Siwetz M, Lang Olip I, et al. Extravillous trophoblasts invade more than uterine arteries: evidence for the invasion of uterine veins. Histochem Cell Biol. 2017;147:353-366 pubmed publisher
  4. Bai H, Wang M, Foster T, Hu H, He H, Hashimoto T, et al. Pericardial patch venoplasty heals via attraction of venous progenitor cells. Physiol Rep. 2016;4: pubmed publisher
  5. Chen I, Caprioli A, Ohnuki H, Kwak H, Porcher C, Tosato G. EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta. Sci Rep. 2016;6:27195 pubmed publisher
  6. Wu M, Ai W, Chen L, Zhao S, Liu E. Bradykinin receptors and EphB2/EphrinB2 pathway in response to high glucose-induced osteoblast dysfunction and hyperglycemia-induced bone deterioration in mice. Int J Mol Med. 2016;37:565-74 pubmed publisher
  7. Dubois F, Leroy C, Simon V, Benistant C, Roche S. YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells. Am J Cancer Res. 2015;5:1972-87 pubmed
  8. Kathawala R, Wei L, Anreddy N, Chen K, Patel A, Alqahtani S, et al. The small molecule tyrosine kinase inhibitor NVP-BHG712 antagonizes ABCC10-mediated paclitaxel resistance: a preclinical and pharmacokinetic study. Oncotarget. 2015;6:510-21 pubmed
  9. Li M, Zhao J, Qiao J, Song C, Zhao Z. EphB4 regulates the growth and migration of pancreatic cancer cells. Tumour Biol. 2014;35:6855-9 pubmed publisher
  10. Villarreal Calderon R, Luévano González A, Aragón Flores M, Zhu H, Yuan Y, Xiang Q, et al. Antral atrophy, intestinal metaplasia, and preneoplastic markers in Mexican children with Helicobacter pylori-positive and Helicobacter pylori-negative gastritis. Ann Diagn Pathol. 2014;18:129-35 pubmed publisher
  11. Guijarro Muñoz I, Sanchez A, Martínez Martínez E, Garcia J, Salas C, Provencio M, et al. Gene expression profiling identifies EPHB4 as a potential predictive biomarker in colorectal cancer patients treated with bevacizumab. Med Oncol. 2013;30:572 pubmed publisher
  12. Rönsch K, Jäger M, Schöpflin A, Danciu M, Lassmann S, Hecht A. Class I and III HDACs and loss of active chromatin features contribute to epigenetic silencing of CDX1 and EPHB tumor suppressor genes in colorectal cancer. Epigenetics. 2011;6:610-22 pubmed
  13. Davalos V, Dopeso H, Castaño J, Wilson A, Vilardell F, Romero Gimenez J, et al. EPHB4 and survival of colorectal cancer patients. Cancer Res. 2006;66:8943-8 pubmed