This is a Validated Antibody Database (VAD) review about human Egr-1, based on 34 published articles (read how Labome selects the articles), using Egr-1 antibody in all methods. It is aimed to help Labome visitors find the most suited Egr-1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Egr-1 synonym: AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (44D5)
  • western blot knockout validation; mouse; loading ...; fig 9b
  • immunocytochemistry; human; 1:400; loading ...; fig 7b
  • western blot; human; loading ...; fig 9d
In order to study the effect of venezuelan equine encephalitis virus on apoptosis and its mechanism, Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4154) was used in western blot knockout validation on mouse samples (fig 9b), in immunocytochemistry on human samples at 1:400 (fig 7b) and in western blot on human samples (fig 9d). J Virol (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR5014(2))
  • western blot; mouse; loading ...; fig e7c
Abcam Egr-1 antibody (Abcam, ab133695) was used in western blot on mouse samples (fig e7c). Nature (2020) ncbi
domestic rabbit monoclonal (EPR5014(2))
  • western blot; human; loading ...; fig s5b
Abcam Egr-1 antibody (Abcam, ab133695) was used in western blot on human samples (fig s5b). Cancer Cell (2019) ncbi
domestic rabbit monoclonal (EPR15916)
  • western blot; human; loading ...; fig 1b
Abcam Egr-1 antibody (Abcam, ab194357) was used in western blot on human samples (fig 1b). Open Biol (2019) ncbi
mouse monoclonal (mAbcam55160)
  • EMSA; human; loading ...; fig 1
Abcam Egr-1 antibody (Abcam, ab55160) was used in EMSA on human samples (fig 1). Oncotarget (2017) ncbi
mouse monoclonal (mAbcam55160)
  • western blot; rat; loading ...; fig 5a
In order to study memory deficits and etomidate anesthesia in aged rat model, Abcam Egr-1 antibody (Abcam, ab55160) was used in western blot on rat samples (fig 5a). Chin Med J (Engl) (2016) ncbi
mouse monoclonal (mAbcam55160)
  • western blot; human; 1:100; fig 5
Abcam Egr-1 antibody (Abcam, ab55160) was used in western blot on human samples at 1:100 (fig 5). Biomed Res Int (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (S-25)
  • western blot; human; 1:1000; loading ...; fig s2h
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz, sc-101033) was used in western blot on human samples at 1:1000 (fig s2h). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (S-25)
  • immunohistochemistry; human; 1:500
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz, SC-101033) was used in immunohistochemistry on human samples at 1:500. Neuropsychopharmacology (2014) ncbi
Invitrogen
domestic rabbit monoclonal (T.126.1)
  • immunohistochemistry; mouse; loading ...; fig s16b
  • western blot; mouse; loading ...; fig 4e
In order to study the roll of a mammalian circular RNA locus in miRNA homeostasis and brain function, Invitrogen Egr-1 antibody (Thermo Fisher, MA5-15009) was used in immunohistochemistry on mouse samples (fig s16b) and in western blot on mouse samples (fig 4e). Science (2017) ncbi
domestic rabbit monoclonal (T.160.5)
  • immunohistochemistry - paraffin section; human; 1:50
Invitrogen Egr-1 antibody (ThermoFisher Scientific, T.160.5) was used in immunohistochemistry - paraffin section on human samples at 1:50. Diagn Pathol (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (15F7)
  • immunocytochemistry; human; 1:200; loading ...; fig s2a
Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4153) was used in immunocytochemistry on human samples at 1:200 (fig s2a). Int J Oncol (2021) ncbi
domestic rabbit monoclonal (44D5)
  • western blot; human; 1:1000; loading ...; fig s2a
  • western blot; mouse; 1:1000; loading ...; fig s2k
Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4154S) was used in western blot on human samples at 1:1000 (fig s2a) and in western blot on mouse samples at 1:1000 (fig s2k). Nat Commun (2021) ncbi
domestic rabbit monoclonal (15F7)
  • western blot; rat; 1:1000; loading ...; fig 1a
Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4153) was used in western blot on rat samples at 1:1000 (fig 1a). J Neurosci (2021) ncbi
domestic rabbit monoclonal (15F7)
  • western blot; mouse; fig 1c
  • western blot; Pseudomonas aeruginosa; loading ...; fig 1c
Cell Signaling Technology Egr-1 antibody (Cell Signaling Technologies, 4153) was used in western blot on mouse samples (fig 1c) and in western blot on Pseudomonas aeruginosa samples (fig 1c). Infect Immun (2019) ncbi
domestic rabbit monoclonal (15F7)
  • immunohistochemistry; mouse; loading ...; fig 2i
Cell Signaling Technology Egr-1 antibody (Cell signaling, 4153) was used in immunohistochemistry on mouse samples (fig 2i). Nat Commun (2019) ncbi
domestic rabbit monoclonal (15F7)
  • immunohistochemistry; rat; 1:1000; loading ...; fig 4
  • western blot; rat; 1:1000; loading ...; fig 3a, 3e, 3i, 3m
Cell Signaling Technology Egr-1 antibody (Cell Signalling Technology, 4153) was used in immunohistochemistry on rat samples at 1:1000 (fig 4) and in western blot on rat samples at 1:1000 (fig 3a, 3e, 3i, 3m). J Oral Rehabil (2019) ncbi
domestic rabbit monoclonal (44D5)
  • immunohistochemistry; mouse; 1:800; loading ...; fig s11d
Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4154) was used in immunohistochemistry on mouse samples at 1:800 (fig s11d). Science (2018) ncbi
domestic rabbit monoclonal (44D5)
  • western blot; mouse; 1:1000; loading ...; fig 3g
Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4154) was used in western blot on mouse samples at 1:1000 (fig 3g). J Biol Chem (2018) ncbi
domestic rabbit monoclonal (15F7)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4b
Cell Signaling Technology Egr-1 antibody (Cell Signaling Technology, 4153) was used in immunohistochemistry on mouse samples at 1:100 (fig 4b). Proc Natl Acad Sci U S A (2017) ncbi
domestic rabbit monoclonal (15F7)
  • western blot; human; 1:1000; loading ...; fig 2d
Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4153S) was used in western blot on human samples at 1:1000 (fig 2d). PLoS ONE (2017) ncbi
domestic rabbit monoclonal (15F7)
  • western blot; human; 1:1000; loading ...; fig s6c
Cell Signaling Technology Egr-1 antibody (CST, 4153) was used in western blot on human samples at 1:1000 (fig s6c). Oncogene (2017) ncbi
domestic rabbit monoclonal (15F7)
  • western blot; human; loading ...; fig 6g
Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4153) was used in western blot on human samples (fig 6g). Oncotarget (2016) ncbi
domestic rabbit monoclonal (15F7)
  • chromatin immunoprecipitation; human; fig s2
  • western blot; human; 1:1000; fig s2
Cell Signaling Technology Egr-1 antibody (Cell Signaling Tech, 4153) was used in chromatin immunoprecipitation on human samples (fig s2) and in western blot on human samples at 1:1000 (fig s2). Nat Commun (2016) ncbi
domestic rabbit monoclonal (15F7)
  • chromatin immunoprecipitation; human; 1:40; fig 3
Cell Signaling Technology Egr-1 antibody (Cell Signaling Tech, 15F7) was used in chromatin immunoprecipitation on human samples at 1:40 (fig 3). Nat Commun (2016) ncbi
domestic rabbit monoclonal (15F7)
  • western blot; mouse; 1:1000; tbl 1
In order to study novelty-induced and brain-specific basal alternations in PI3K-Akt and MAPK/ERK signaling in a middle-aged A-betaPP/PS1 mouse model of Alzheimer's disease, Cell Signaling Technology Egr-1 antibody (CST, 4153) was used in western blot on mouse samples at 1:1000 (tbl 1). J Alzheimers Dis (2016) ncbi
domestic rabbit monoclonal (44D5)
  • western blot knockout validation; mouse; loading ...; fig 9b
  • immunocytochemistry; human; 1:400; loading ...; fig 7b
  • western blot; human; loading ...; fig 9d
In order to study the effect of venezuelan equine encephalitis virus on apoptosis and its mechanism, Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4154) was used in western blot knockout validation on mouse samples (fig 9b), in immunocytochemistry on human samples at 1:400 (fig 7b) and in western blot on human samples (fig 9d). J Virol (2016) ncbi
domestic rabbit monoclonal (15F7)
  • chromatin immunoprecipitation; human; fig s3
Cell Signaling Technology Egr-1 antibody (Cell Signaling Techn, 4153) was used in chromatin immunoprecipitation on human samples (fig s3). BMC Cell Biol (2015) ncbi
domestic rabbit monoclonal (15F7)
  • western blot; human; fig 8a
Cell Signaling Technology Egr-1 antibody (Cell signaling, 4153) was used in western blot on human samples (fig 8a). Biomolecules (2015) ncbi
domestic rabbit monoclonal (15F7)
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 7
In order to elucidate role of androgen signaling in beta-catenin-initiated prostate tumorigenesis, Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4153) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 7). Oncogene (2016) ncbi
domestic rabbit monoclonal (15F7)
  • immunohistochemistry - paraffin section; rat; 1:200
Cell Signaling Technology Egr-1 antibody (Cell Signaling, #4153) was used in immunohistochemistry - paraffin section on rat samples at 1:200. Neuroscience (2015) ncbi
domestic rabbit monoclonal (15F7)
  • western blot; human; fig 5
Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4153) was used in western blot on human samples (fig 5). Sci Rep (2015) ncbi
domestic rabbit monoclonal (15F7)
  • western blot; human; fig  3
Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4153) was used in western blot on human samples (fig  3). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (15F7)
  • immunohistochemistry; rat; 1:250
Cell Signaling Technology Egr-1 antibody (Cell Signalling Technology, 15F7) was used in immunohistochemistry on rat samples at 1:250. J Chem Neuroanat (2014) ncbi
domestic rabbit monoclonal (15F7)
  • immunohistochemistry - frozen section; human; 1:50; fig 4
In order to analyze developing cerebral cortex and low-coverage single-cell mRNA sequencing that reveals activated signaling pathways and cellular heterogeneity, Cell Signaling Technology Egr-1 antibody (Cell signaling, 41535) was used in immunohistochemistry - frozen section on human samples at 1:50 (fig 4). Nat Biotechnol (2014) ncbi
Articles Reviewed
  1. Takenaga K, Ochiya T, Endo H. Inhibition of the invasion and metastasis of mammary carcinoma cells by NBD peptide targeting S100A4 via the suppression of the Sp1/MMP‑14 axis. Int J Oncol. 2021;58:397-408 pubmed publisher
  2. Vaughan C, Singh S, Subler M, Windle J, Inoue K, Fry E, et al. The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3. Nat Commun. 2021;12:704 pubmed publisher
  3. Jiang S, Sweat S, Dahlke S, Loane K, Drossel G, Xu W, et al. Cocaine-Dependent Acquisition of Locomotor Sensitization and Conditioned Place Preference Requires D1 Dopaminergic Signaling through a Cyclic AMP, NCS-Rapgef2, ERK, and Egr-1/Zif268 Pathway. J Neurosci. 2021;41:711-725 pubmed publisher
  4. Lu Z, Zou J, Li S, Topper M, Tao Y, Zhang H, et al. Epigenetic therapy inhibits metastases by disrupting premetastatic niches. Nature. 2020;579:284-290 pubmed publisher
  5. Pang Z, Raudonis R, McCormick C, Cheng Z. Early Growth Response 1 Deficiency Protects the Host against Pseudomonas aeruginosa Lung Infection. Infect Immun. 2019;88: pubmed publisher
  6. Gomes A, Ilter D, Low V, Rosenzweig A, Shen Z, Schild T, et al. Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization. Cancer Cell. 2019;36:402-417.e13 pubmed publisher
  7. Littler S, Sloss O, Geary B, Pierce A, Whetton A, Taylor S. Oncogenic MYC amplifies mitotic perturbations. Open Biol. 2019;9:190136 pubmed publisher
  8. Zhu Y, Huang M, Bushong E, Phan S, Uytiepo M, Beutter E, et al. Class IIa HDACs regulate learning and memory through dynamic experience-dependent repression of transcription. Nat Commun. 2019;10:3469 pubmed publisher
  9. Zhang H, Liu Q, Liu J, Wang J, Yang H, Xu X, et al. Molecular changes in peripheral blood involving osteoarthritic joint remodelling. J Oral Rehabil. 2019;: pubmed publisher
  10. Bugaj L, Sabnis A, Mitchell A, Garbarino J, Toettcher J, Bivona T, et al. Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway. Science. 2018;361: pubmed publisher
  11. Choi S, Neequaye P, French S, Gonzalez F, Gyamfi M. Pregnane X receptor promotes ethanol-induced hepatosteatosis in mice. J Biol Chem. 2018;293:1-17 pubmed publisher
  12. Piwecka M, Glažar P, Hernández Miranda L, Memczak S, Wolf S, Rybak Wolf A, et al. Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function. Science. 2017;357: pubmed publisher
  13. Oh J, Wang Y, Chen S, Li P, Du N, Yu Z, et al. Genetic background-dependent role of Egr1 for eyelid development. Proc Natl Acad Sci U S A. 2017;114:E7131-E7139 pubmed publisher
  14. Collombet S, van Oevelen C, Sardina Ortega J, Abou Jaoudé W, Di Stefano B, Thomas Chollier M, et al. Logical modeling of lymphoid and myeloid cell specification and transdifferentiation. Proc Natl Acad Sci U S A. 2017;114:5792-5799 pubmed publisher
  15. Zhang Y, Zhou X, Cheng F, Qi Y, Hou P, Zhao M, et al. Autophagy-related gene LRRK2 is likely a susceptibility gene for systemic lupus erythematosus in northern Han Chinese. Oncotarget. 2017;8:13754-13761 pubmed publisher
  16. Laporte A, Barrott J, Yao R, Poulin N, Brodin B, Jones K, et al. HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma. PLoS ONE. 2017;12:e0169407 pubmed publisher
  17. Kesarwani A, Ramirez O, Gupta A, Yang X, Murthy T, Minella A, et al. Cancer-associated SF3B1 mutants recognize otherwise inaccessible cryptic 3' splice sites within RNA secondary structures. Oncogene. 2017;36:1123-1133 pubmed publisher
  18. Laporte A, Ji J, Ma L, Nielsen T, Brodin B. Identification of cytotoxic agents disrupting synovial sarcoma oncoprotein interactions by proximity ligation assay. Oncotarget. 2016;7:34384-94 pubmed publisher
  19. Wu S, Rupaimoole R, Shen F, Pradeep S, Pecot C, Ivan C, et al. A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer. Nat Commun. 2016;7:11169 pubmed publisher
  20. Weigel C, Veldwijk M, Oakes C, Seibold P, Slynko A, Liesenfeld D, et al. Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis. Nat Commun. 2016;7:10893 pubmed publisher
  21. Guillot F, Kemppainen S, Lavasseur G, Miettinen P, Laroche S, Tanila H, et al. Brain-Specific Basal and Novelty-Induced Alternations in PI3K-Akt and MAPK/ERK Signaling in a Middle-Aged AβPP/PS1 Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2016;51:1157-73 pubmed publisher
  22. Baer A, Lundberg L, Swales D, Waybright N, Pinkham C, Dinman J, et al. Venezuelan Equine Encephalitis Virus Induces Apoptosis through the Unfolded Protein Response Activation of EGR1. J Virol. 2016;90:3558-72 pubmed publisher
  23. Li X, Lu F, Li W, Xu J, Sun X, Qin L, et al. Underlying Mechanisms of Memory Deficits Induced by Etomidate Anesthesia in Aged Rat Model: Critical Role of Immediate Early Genes. Chin Med J (Engl). 2016;129:48-53 pubmed publisher
  24. Ponti D, Bastianelli D, Rosa P, Pacini L, Ibrahim M, Rendina E, et al. The expression of B23 and EGR1 proteins is functionally linked in tumor cells under stress conditions. BMC Cell Biol. 2015;16:27 pubmed publisher
  25. Sobolewski C, Sanduja S, Blanco F, Hu L, Dixon D. Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells. Biomolecules. 2015;5:2035-55 pubmed publisher
  26. Marthandan S, Priebe S, Baumgart M, Groth M, Cellerino A, Guthke R, et al. Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts. Biomed Res Int. 2015;2015:731938 pubmed publisher
  27. Lee S, Luong R, Johnson D, Cunha G, Rivina L, Gonzalgo M, et al. Androgen signaling is a confounding factor for β-catenin-mediated prostate tumorigenesis. Oncogene. 2016;35:702-14 pubmed publisher
  28. Liu W, Crews F. Adolescent intermittent ethanol exposure enhances ethanol activation of the nucleus accumbens while blunting the prefrontal cortex responses in adult rat. Neuroscience. 2015;293:92-108 pubmed publisher
  29. Kobayashi K, Sakurai K, Hiramatsu H, Inada K, Shiogama K, Nakamura S, et al. The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines. Sci Rep. 2015;5:8428 pubmed publisher
  30. Dong A, Wodziak D, Lowe A. Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface. J Biol Chem. 2015;290:8016-27 pubmed publisher
  31. Vogels R, Vlenterie M, Versleijen Jonkers Y, Ruijter E, Bekers E, Verdijk M, et al. Solitary fibrous tumor - clinicopathologic, immunohistochemical and molecular analysis of 28 cases. Diagn Pathol. 2014;9:224 pubmed publisher
  32. Hoefflin S, Carter D. Neuronal expression of SOX2 is enriched in specific hypothalamic cell groups. J Chem Neuroanat. 2014;61-62:153-60 pubmed publisher
  33. Pollen A, Nowakowski T, Shuga J, Wang X, Leyrat A, Lui J, et al. Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex. Nat Biotechnol. 2014;32:1053-8 pubmed publisher
  34. Bannon M, Johnson M, Michelhaugh S, Hartley Z, Halter S, David J, et al. A molecular profile of cocaine abuse includes the differential expression of genes that regulate transcription, chromatin, and dopamine cell phenotype. Neuropsychopharmacology. 2014;39:2191-9 pubmed publisher