This is a Validated Antibody Database (VAD) review about human EXO1, based on 7 published articles (read how Labome selects the articles), using EXO1 antibody in all methods. It is aimed to help Labome visitors find the most suited EXO1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
EXO1 synonym: HEX1; hExoI; exonuclease 1; rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1

Knockout validation
Bethyl
rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig s1b
Bethyl EXO1 antibody (Bethyl Laboratories, A302-639A) was used in western blot knockout validation on human samples at 1:1000 (fig s1b). Nat Commun (2018) ncbi
Bethyl
rabbit polyclonal
  • western blot knockout validation; mouse; 1:5000; fig 1d
Bethyl EXO1 antibody (Bethyl, A302-640A) was used in western blot knockout validation on mouse samples at 1:5000 (fig 1d). Nucleic Acids Res (2015) ncbi
Bethyl
rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig s1b
Bethyl EXO1 antibody (Bethyl Laboratories, A302-639A) was used in western blot knockout validation on human samples at 1:1000 (fig s1b). Nat Commun (2018) ncbi
rabbit polyclonal
  • western blot; mouse; fig 5d
Bethyl EXO1 antibody (Bethyl Laboratories, A302-640A) was used in western blot on mouse samples (fig 5d). Mol Cell (2016) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; 1:5000; fig 1d
Bethyl EXO1 antibody (Bethyl, A302-640A) was used in western blot knockout validation on mouse samples at 1:5000 (fig 1d). Nucleic Acids Res (2015) ncbi
rabbit polyclonal
  • reverse phase protein lysate microarray; human; 1:1000; fig 4
In order to identify a novel DNA2- and WRN-dependent mechanism of reversed replication fork processing and restart after prolonged genotoxic stress, Bethyl EXO1 antibody (Bethyl, A302-639A) was used in reverse phase protein lysate microarray on human samples at 1:1000 (fig 4). J Cell Biol (2015) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; fig 5
Bethyl EXO1 antibody (Bethyl Laboratories, A302-639A) was used in chromatin immunoprecipitation on human samples (fig 5). Cell (2015) ncbi
Abcam
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Abcam EXO1 antibody (Abcam, ab95012) was used in western blot on human samples at 1:1000 (fig 3). Nat Commun (2015) ncbi
Invitrogen
mouse monoclonal (266)
  • western blot; human; 1:200
In order to study the effect of ASF1 depletion on the alternative lengthening of telomeres, Invitrogen EXO1 antibody (Thermo, MS-1534) was used in western blot on human samples at 1:200. Nat Struct Mol Biol (2014) ncbi
Articles Reviewed
  1. Zou X, Owusu M, Harris R, Jackson S, Loizou J, Nik Zainal S. Validating the concept of mutational signatures with isogenic cell models. Nat Commun. 2018;9:1744 pubmed publisher
  2. Kibe T, Zimmermann M, de Lange T. TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres. Mol Cell. 2016;61:236-46 pubmed publisher
  3. Lee K, Im J, Shibata E, Park J, Handa N, Kowalczykowski S, et al. MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex. Nat Commun. 2015;6:7744 pubmed publisher
  4. Rein K, Yanez D, Terré B, Palenzuela L, Aivio S, Wei K, et al. EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele. Nucleic Acids Res. 2015;43:7371-87 pubmed publisher
  5. Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, et al. DNA2 drives processing and restart of reversed replication forks in human cells. J Cell Biol. 2015;208:545-62 pubmed publisher
  6. Puc J, Kozbial P, Li W, Tan Y, Liu Z, Suter T, et al. Ligand-dependent enhancer activation regulated by topoisomerase-I activity. Cell. 2015;160:367-80 pubmed publisher
  7. O Sullivan R, Arnoult N, Lackner D, Oganesian L, Haggblom C, Corpet A, et al. Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1. Nat Struct Mol Biol. 2014;21:167-74 pubmed publisher