This is a Validated Antibody Database (VAD) review about human ESRRA, based on 12 published articles (read how Labome selects the articles), using ESRRA antibody in all methods. It is aimed to help Labome visitors find the most suited ESRRA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ESRRA synonym: ERR1; ERRa; ERRalpha; ESRL1; NR3B1; steroid hormone receptor ERR1; ERR-alpha; estrogen receptor-like 1; estrogen-related nuclear receptor alpha; nuclear receptor subfamily 3 group B member 1

Knockout validation
Abcam
rabbit monoclonal (EPR46Y)
  • western blot knockout validation; mouse; fig 1f
Abcam ESRRA antibody (Abcam, ab76228) was used in western blot knockout validation on mouse samples (fig 1f). Endocrinology (2016) ncbi
Cell Signaling Technology
rabbit monoclonal (E1G1J)
  • western blot; human; fig s11b
  • western blot knockout validation; mouse; fig s14c
Cell Signaling Technology ESRRA antibody (Cell Signaling, 13826) was used in western blot on human samples (fig s11b) and in western blot knockout validation on mouse samples (fig s14c). J Clin Invest (2017) ncbi
Abcam
rabbit monoclonal (EPR46Y)
  • western blot; human; loading ...; fig 4a
Abcam ESRRA antibody (abcam, ab76228) was used in western blot on human samples (fig 4a). Cell Rep (2019) ncbi
rabbit monoclonal (EPR46Y)
  • western blot knockout validation; mouse; fig 1f
Abcam ESRRA antibody (Abcam, ab76228) was used in western blot knockout validation on mouse samples (fig 1f). Endocrinology (2016) ncbi
rabbit monoclonal (EPR46Y)
  • ChIP-Seq; human; fig s1c
  • immunohistochemistry; human; 1:100; fig s1a
  • western blot; human; 1:500; fig s1a
Abcam ESRRA antibody (Abcam, 2131-1) was used in ChIP-Seq on human samples (fig s1c), in immunohistochemistry on human samples at 1:100 (fig s1a) and in western blot on human samples at 1:500 (fig s1a). Nat Commun (2016) ncbi
rabbit monoclonal (EPR46Y)
Abcam ESRRA antibody (Abcam, ab76228) was used . J Am Heart Assoc (2012) ncbi
rabbit monoclonal (EPR46Y)
  • immunoprecipitation; human; 1:40
  • immunocytochemistry; human
  • western blot; human; 1:1000
Abcam ESRRA antibody (Abcam, ab76228) was used in immunoprecipitation on human samples at 1:40, in immunocytochemistry on human samples and in western blot on human samples at 1:1000. Mol Pharmacol (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (1ERR87)
  • western blot; human; loading ...; fig 2c
Santa Cruz Biotechnology ESRRA antibody (Santa Cruz, sc-65715) was used in western blot on human samples (fig 2c). Oncotarget (2016) ncbi
mouse monoclonal (1ERR87)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Santa Cruz Biotechnology ESRRA antibody (Santa Cruz Biotechnology, 1ERR87) was used in immunohistochemistry - paraffin section on human samples (fig 1a). J Clin Pathol (2014) ncbi
GeneTex
rabbit polyclonal
  • western blot; human; fig 1
GeneTex ESRRA antibody (Gentex, GTX108166) was used in western blot on human samples (fig 1). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:2500; fig 3
GeneTex ESRRA antibody (Genetex, GTX108166) was used in western blot on human samples at 1:2500 (fig 3). PLoS ONE (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (E1G1J)
  • western blot; human; fig s11b
  • western blot knockout validation; mouse; fig s14c
Cell Signaling Technology ESRRA antibody (Cell Signaling, 13826) was used in western blot on human samples (fig s11b) and in western blot knockout validation on mouse samples (fig s14c). J Clin Invest (2017) ncbi
rabbit monoclonal (E1G1J)
  • western blot; human; loading ...; fig s3
In order to research the oncogenic effect of NRF2 and its mechanism, Cell Signaling Technology ESRRA antibody (Cell Signaling, 13826) was used in western blot on human samples (fig s3). Oncotarget (2016) ncbi
rabbit monoclonal (E1G1J)
  • western blot; human; 1:1000; loading ...; fig s6d
In order to show that the transcriptional the peroxisome proliferator-activated receptor gamma co-activator alpha suppresses prostate cancer progression and metastasis, Cell Signaling Technology ESRRA antibody (Cell Signalling, 13826) was used in western blot on human samples at 1:1000 (fig s6d). Nat Cell Biol (2016) ncbi
Articles Reviewed
  1. Park S, Safi R, Liu X, Baldi R, Liu W, Liu J, et al. Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer. Cell Rep. 2019;27:3587-3601.e4 pubmed publisher
  2. Bae S, Lee M, Mun S, Giannopoulou E, Yong Gonzalez V, Cross J, et al. MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERR?. J Clin Invest. 2017;127:2555-2568 pubmed publisher
  3. Gantner M, Hazen B, Eury E, Brown E, Kralli A. Complementary Roles of Estrogen-Related Receptors in Brown Adipocyte Thermogenic Function. Endocrinology. 2016;157:4770-4781 pubmed
  4. Zhang C, Wang H, Bao Q, Wang L, Guo T, Chen W, et al. NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction. Oncotarget. 2016;7:73593-73606 pubmed publisher
  5. Deblois G, Smith H, Tam I, Gravel S, Caron M, Savage P, et al. ERR? mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nat Commun. 2016;7:12156 pubmed publisher
  6. Tribollet V, Barenton B, Kroiss A, Vincent S, Zhang L, Forcet C, et al. miR-135a Inhibits the Invasion of Cancer Cells via Suppression of ERR?. PLoS ONE. 2016;11:e0156445 pubmed publisher
  7. Torrano V, Valcarcel Jimenez L, Cortazar A, Liu X, Urosevic J, Castillo Martin M, et al. The metabolic co-regulator PGC1α suppresses prostate cancer metastasis. Nat Cell Biol. 2016;18:645-656 pubmed publisher
  8. Matsushima H, Mori T, Ito F, Yamamoto T, Akiyama M, Kokabu T, et al. Anti-tumor effect of estrogen-related receptor alpha knockdown on uterine endometrial cancer. Oncotarget. 2016;7:34131-48 pubmed publisher
  9. Carnesecchi J, Malbouyres M, de Mets R, Balland M, Beauchef G, Vié K, et al. Estrogens induce rapid cytoskeleton re-organization in human dermal fibroblasts via the non-classical receptor GPR30. PLoS ONE. 2015;10:e0120672 pubmed publisher
  10. Harada K, Kakuda Y, Sato Y, Ikeda H, Shimoda S, Yamamoto Y, et al. Alteration of energy metabolism in the pathogenesis of bile duct lesions in primary biliary cirrhosis. J Clin Pathol. 2014;67:396-402 pubmed publisher
  11. Wan X, Gupta S, Zago M, Davidson M, Dousset P, Amoroso A, et al. Defects of mtDNA replication impaired mitochondrial biogenesis during Trypanosoma cruzi infection in human cardiomyocytes and chagasic patients: the role of Nrf1/2 and antioxidant response. J Am Heart Assoc. 2012;1:e003855 pubmed publisher
  12. Krzysik Walker S, González Mariscal I, Scheibye Knudsen M, Indig F, Bernier M. The biarylpyrazole compound AM251 alters mitochondrial physiology via proteolytic degradation of ERR?. Mol Pharmacol. 2013;83:157-66 pubmed publisher