This is a Validated Antibody Database (VAD) review about human ERbeta, based on 32 published articles (read how Labome selects the articles), using ERbeta antibody in all methods. It is aimed to help Labome visitors find the most suited ERbeta antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ERbeta synonym: ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8

Knockout validation
Invitrogen
mouse monoclonal (PPZ0506)
  • western blot knockout validation; mouse; loading ...; fig 1c
Invitrogen ERbeta antibody (Thermo Fisher, PPZ0506) was used in western blot knockout validation on mouse samples (fig 1c). Front Cell Dev Biol (2021) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:3000; loading ...; fig 4b
Invitrogen ERbeta antibody (Invitrogen, PA1-311) was used in western blot knockout validation on mouse samples at 1:3000 (fig 4b). Int J Mol Sci (2019) ncbi
Developmental Studies Hybridoma Bank
mouse monoclonal (CWK-F12)
  • western blot knockout validation; mouse; loading ...; fig 1c
  • immunoprecipitation; mouse; loading ...; fig 3b
Developmental Studies Hybridoma Bank ERbeta antibody (DSHB, CWK-F12) was used in western blot knockout validation on mouse samples (fig 1c) and in immunoprecipitation on mouse samples (fig 3b). Front Cell Dev Biol (2021) ncbi
Invitrogen
mouse monoclonal (PPZ0506)
  • western blot knockout validation; mouse; loading ...; fig 1c
Invitrogen ERbeta antibody (Thermo Fisher, PPZ0506) was used in western blot knockout validation on mouse samples (fig 1c). Front Cell Dev Biol (2021) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig 3b
Invitrogen ERbeta antibody (Thermo Fisher, 51-7700) was used in immunoprecipitation on mouse samples (fig 3b). Front Cell Dev Biol (2021) ncbi
mouse monoclonal (MC10)
  • immunoprecipitation; mouse; loading ...; fig 3b
Invitrogen ERbeta antibody (Thermo Fisher, MC10) was used in immunoprecipitation on mouse samples (fig 3b). Front Cell Dev Biol (2021) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig 3b
Invitrogen ERbeta antibody (Thermo Fisher, PAI-311) was used in immunoprecipitation on mouse samples (fig 3b). Front Cell Dev Biol (2021) ncbi
mouse monoclonal (PPZ0506)
  • western blot; human; 1:500; loading ...; fig 1
Invitrogen ERbeta antibody (Thermo Fisher, MA5-24807) was used in western blot on human samples at 1:500 (fig 1). BMC Cancer (2019) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:3000; loading ...; fig 4b
Invitrogen ERbeta antibody (Invitrogen, PA1-311) was used in western blot knockout validation on mouse samples at 1:3000 (fig 4b). Int J Mol Sci (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 3a
In order to report how hormonal changes affect striae distensae pathogenesis, Invitrogen ERbeta antibody (Thermo Fisher Scientific, PA1-310B) was used in immunohistochemistry - paraffin section on human samples (fig 3a). J Cosmet Dermatol (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; 1:1000; loading ...; fig 5d
In order to examine the cross talk between the aryl hydrocarbon receptor and the estrogen receptor on a mRNA transcriptome wide scale, Invitrogen ERbeta antibody (Thermo Fisher Scientific, PA1-311) was used in immunohistochemistry - paraffin section on rat samples at 1:1000 (fig 5d). J Steroid Biochem Mol Biol (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; hamsters; loading ...; fig 3
  • western blot; hamsters; 1:600; loading ...; fig 4a
In order to elucidate the role of estrogen in embryo implantation in golden hamster, Invitrogen ERbeta antibody (Thermo fisher, PA1-311) was used in immunohistochemistry - paraffin section on hamsters samples (fig 3) and in western blot on hamsters samples at 1:600 (fig 4a). Life Sci (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:150; loading ...; fig 6a
In order to determine the incidence of adenomyosis and the expression of estrogen receptors in uterus of mice exposed to TCDD., Invitrogen ERbeta antibody (Thermo-Scientific, PA1-310B) was used in immunohistochemistry - paraffin section on mouse samples at 1:150 (fig 6a). Biol Reprod (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig 1
In order to analyze a Wisconsin oncology network study of metastatic triple-negative breast cancer where targeting estrogen receptor beta in a phase 2 study of high-dose estradiol, Invitrogen ERbeta antibody (Thermo Scientific, PA1-313) was used in immunohistochemistry - paraffin section on human samples (fig 1). Clin Breast Cancer (2016) ncbi
domestic rabbit polyclonal
  • flow cytometry; bovine; 1:50; fig 6
In order to study bovine mammary epithelial cells during staphylococcus aureus internalization and the antimicrobial and anti-inflammatory effects of estradiol, Invitrogen ERbeta antibody (Life technologies, 517700) was used in flow cytometry on bovine samples at 1:50 (fig 6). Mediators Inflamm (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:100; fig 4
In order to discover how estrogenic compounds reduce infuenza A virus replication in nasal epithelial cells from females and not males, Invitrogen ERbeta antibody (Thermo, PA1-310B) was used in western blot on human samples at 1:100 (fig 4). Am J Physiol Lung Cell Mol Physiol (2016) ncbi
domestic rabbit polyclonal
In order to determine the critical window for estrogen therapy, Invitrogen ERbeta antibody (Invitrogen, 51-7700) was used . J Neurosci (2015) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:500; fig 2
  • western blot; human; fig 1
In order to test if osteoblasts regulate the intratumoral steroidogenesis of castration-resistant prostate cancer, Invitrogen ERbeta antibody (Thermo Scientific, PA1-311) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 2) and in western blot on human samples (fig 1). Mol Cell Endocrinol (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; fig 1
  • western blot; mouse; fig 1
In order to investigate how estrogen receptor-alpha signaling suppresses visceral fat development, Invitrogen ERbeta antibody (Invitrogen, 51-7700) was used in immunocytochemistry on mouse samples (fig 1) and in western blot on mouse samples (fig 1). FASEB J (2016) ncbi
domestic rabbit polyclonal
In order to test if H3K27Me3 demethylation affects transcription and cell differentiation, Invitrogen ERbeta antibody (Thermo Scientific, PA1-313) was used . Nat Commun (2015) ncbi
domestic rabbit polyclonal
In order to examine the association between ERbeta1 and Ki67 expression in non-metastatic triple negative breast cancer, Invitrogen ERbeta antibody (Thermo Scientific, PA1-313) was used . Am J Transl Res (2015) ncbi
domestic rabbit polyclonal
In order to determine the contribution of ESR2 to medulloblastoma growth in vitro and in vivo, Invitrogen ERbeta antibody (Affinity BioReagents, PA1-310B) was used . Endocrinology (2015) ncbi
domestic rabbit polyclonal
In order to study STAT3 and mTOR signaling in patients with polycystic ovary syndrome, Invitrogen ERbeta antibody (Pierce Biotechnology, PA1-310B) was used . Hum Reprod (2015) ncbi
domestic rabbit polyclonal
In order to test the effect of methoxychlor/HPTE on FSH-stimulated cAMP production in cultured granulosa cells, Invitrogen ERbeta antibody (Pierce, PA1310B) was used . Reprod Toxicol (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-1)
  • immunohistochemistry; rat; 1:700; loading ...; fig 1a
In order to elucidate RAS-mediated signaling induced by estradiol treatment, Santa Cruz Biotechnology ERbeta antibody (Santa Cruz, sc-390243) was used in immunohistochemistry on rat samples at 1:700 (fig 1a). Neuropsychopharmacology (2016) ncbi
mouse monoclonal (1531)
  • western blot; rat; fig 9
Santa Cruz Biotechnology ERbeta antibody (Santa Cruz, sc-53494) was used in western blot on rat samples (fig 9). J Am Heart Assoc (2016) ncbi
mouse monoclonal (B-1)
  • western blot; human; fig 1
Santa Cruz Biotechnology ERbeta antibody (Santa Cruz, sc-390243) was used in western blot on human samples (fig 1). Front Endocrinol (Lausanne) (2015) ncbi
mouse monoclonal (B-3)
  • western blot; human
Santa Cruz Biotechnology ERbeta antibody (Santa Cruz, sc-373853) was used in western blot on human samples . Cancer Res (2014) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; mouse; 1:750; loading ...; fig s4a
Abcam ERbeta antibody (Abcam, ab3576) was used in western blot on mouse samples at 1:750 (fig s4a). Nat Commun (2018) ncbi
mouse monoclonal (14C8)
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 1
Abcam ERbeta antibody (Abcam, 28-8) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 1). Neurosurgery (2018) ncbi
mouse monoclonal (14C8)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3a
Abcam ERbeta antibody (Abcam, 28-8) was used in immunohistochemistry - paraffin section on mouse samples (fig 3a). Science (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:100; fig 1
  • western blot; mouse; 1:500; fig 1
Abcam ERbeta antibody (Abcam, ab3576) was used in immunohistochemistry on mouse samples at 1:100 (fig 1) and in western blot on mouse samples at 1:500 (fig 1). Sci Rep (2016) ncbi
Bio-Rad
mouse monoclonal (57/3)
  • immunocytochemistry; human; 1:100
Bio-Rad ERbeta antibody (Serotec, 57/3) was used in immunocytochemistry on human samples at 1:100. Breast Cancer Res Treat (2014) ncbi
mouse monoclonal (5/25)
  • immunohistochemistry - paraffin section; human; 1:250
Bio-Rad ERbeta antibody (Serotec, 5/25) was used in immunohistochemistry - paraffin section on human samples at 1:250. Breast Cancer Res Treat (2014) ncbi
mouse monoclonal (5/25)
  • immunohistochemistry - paraffin section; human; loading ...
In order to study the sensitivity of the rabbit monoclonal antibodies SP1 and 1D5 towards the estrogen receptor, Bio-Rad ERbeta antibody (Serotec, 5/25) was used in immunohistochemistry - paraffin section on human samples . Appl Immunohistochem Mol Morphol (2013) ncbi
GeneTex
mouse monoclonal (7B10.7)
  • western blot; human; 1:200; loading ...; fig 1c
In order to validate ERbeta antibodies in n MCF-7 and LNCaP cancer cell lines., GeneTex ERbeta antibody (GeneTex, 70182) was used in western blot on human samples at 1:200 (fig 1c). Mol Cell Endocrinol (2017) ncbi
mouse monoclonal (7B10.7)
  • chromatin immunoprecipitation; human
GeneTex ERbeta antibody (GeneTex, GTX70182) was used in chromatin immunoprecipitation on human samples . Endocrinology (2010) ncbi
mouse monoclonal (7B10.7)
  • chromatin immunoprecipitation; human; fig 1
GeneTex ERbeta antibody (GeneTex, GTX70182) was used in chromatin immunoprecipitation on human samples (fig 1). Mol Endocrinol (2010) ncbi
Abnova
mouse monoclonal (3F3)
  • western blot; rat; 1:500; fig s2
Abnova ERbeta antibody (Abnova, H00002100-M01) was used in western blot on rat samples at 1:500 (fig s2). Life Sci (2015) ncbi
Developmental Studies Hybridoma Bank
mouse monoclonal (CWK-F12)
  • western blot knockout validation; mouse; loading ...; fig 1c
  • immunoprecipitation; mouse; loading ...; fig 3b
Developmental Studies Hybridoma Bank ERbeta antibody (DSHB, CWK-F12) was used in western blot knockout validation on mouse samples (fig 1c) and in immunoprecipitation on mouse samples (fig 3b). Front Cell Dev Biol (2021) ncbi
Articles Reviewed
  1. Yuan B, Yang J, Dubeau L, Hu Y, Li R. A Phosphotyrosine Switch in Estrogen Receptor β Is Required for Mouse Ovarian Function. Front Cell Dev Biol. 2021;9:649087 pubmed publisher
  2. Treeck O, Diepolder E, Skrzypczak M, Schüler Toprak S, Ortmann O. Knockdown of estrogen receptor β increases proliferation and affects the transcriptome of endometrial adenocarcinoma cells. BMC Cancer. 2019;19:745 pubmed publisher
  3. Kim H, Park J, Leem H, Cho M, Yoon J, Maeng H, et al. Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress. Int J Mol Sci. 2019;20: pubmed publisher
  4. Maani N, Sabha N, Rezai K, Ramani A, Groom L, Eltayeb N, et al. Tamoxifen therapy in a murine model of myotubular myopathy. Nat Commun. 2018;9:4849 pubmed publisher
  5. Pratt D, Dominah G, Lobel G, Obungu A, Lynes J, Sanchez V, et al. Programmed Death Ligand 1 Is a Negative Prognostic Marker in Recurrent Isocitrate Dehydrogenase-Wildtype Glioblastoma. Neurosurgery. 2018;: pubmed publisher
  6. Youssef S, El Khateeb E, Aly D, Moussa M. Striae distensae: Immunohistochemical assessment of hormone receptors in multigravida and nulligravida. J Cosmet Dermatol. 2017;16:279-286 pubmed publisher
  7. Helle J, Keiler A, Zierau O, Dörfelt P, Vollmer G, Lehmann L, et al. Effects of the aryl hydrocarbon receptor agonist 3-methylcholanthrene on the 17?-estradiol regulated mRNA transcriptome of the rat uterus. J Steroid Biochem Mol Biol. 2017;171:133-143 pubmed publisher
  8. Kumar R, Yadav A, Pakrasi P. Expression of ER-? and ER-? during peri-implantation period in uterus is essential for implantation and decidualization in golden hamster. Life Sci. 2017;170:115-122 pubmed publisher
  9. Nelson A, Groen A, Miller J, Warren A, Holmes K, Tarulli G, et al. Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity. Mol Cell Endocrinol. 2017;440:138-150 pubmed publisher
  10. Bruner Tran K, Duleba A, Taylor H, Osteen K. Developmental Toxicant Exposure Is Associated with Transgenerational Adenomyosis in a Murine Model. Biol Reprod. 2016;95:73 pubmed publisher
  11. Dorand R, Nthale J, Myers J, Barkauskas D, Avril S, Chirieleison S, et al. Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity. Science. 2016;353:399-403 pubmed publisher
  12. Wang W, Kantorovich S, Babayan A, Hou B, Gall C, Lynch G. Estrogen's Effects on Excitatory Synaptic Transmission Entail Integrin and TrkB Transactivation and Depend Upon ?1-integrin function. Neuropsychopharmacology. 2016;41:2723-32 pubmed publisher
  13. Wisinski K, Xu W, Tevaarwerk A, Saha S, Kim K, Traynor A, et al. Targeting Estrogen Receptor Beta in a Phase 2 Study of High-Dose Estradiol in Metastatic Triple-Negative Breast Cancer: A Wisconsin Oncology Network Study. Clin Breast Cancer. 2016;16:256-61 pubmed publisher
  14. Medina Estrada I, López Meza J, Ochoa Zarzosa A. Anti-Inflammatory and Antimicrobial Effects of Estradiol in Bovine Mammary Epithelial Cells during Staphylococcus aureus Internalization. Mediators Inflamm. 2016;2016:6120509 pubmed publisher
  15. Ma Y, Guo H, Zhang L, Tao L, Yin A, Liu Z, et al. Estrogen replacement therapy-induced neuroprotection against brain ischemia-reperfusion injury involves the activation of astrocytes via estrogen receptor β. Sci Rep. 2016;6:21467 pubmed publisher
  16. Iorga A, Li J, Sharma S, Umar S, Bopassa J, Nadadur R, et al. Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. J Am Heart Assoc. 2016;5: pubmed publisher
  17. Peretz J, Pekosz A, Lane A, Klein S. Estrogenic compounds reduce influenza A virus replication in primary human nasal epithelial cells derived from female, but not male, donors. Am J Physiol Lung Cell Mol Physiol. 2016;310:L415-25 pubmed publisher
  18. Bean L, Kumar A, Rani A, Guidi M, Rosario A, Cruz P, et al. Re-Opening the Critical Window for Estrogen Therapy. J Neurosci. 2015;35:16077-93 pubmed publisher
  19. Hagberg Thulin M, Nilsson M, Thulin P, Céraline J, Ohlsson C, Damber J, et al. Osteoblasts promote castration-resistant prostate cancer by altering intratumoral steroidogenesis. Mol Cell Endocrinol. 2016;422:182-191 pubmed publisher
  20. Radhika N, Govindaraj V, Sarangi S, Rao A. Neonatal exposure to 17β-estradiol down-regulates the expression of synaptogenesis related genes in selected brain regions of adult female rats. Life Sci. 2015;141:1-7 pubmed publisher
  21. Pedram A, Razandi M, Blumberg B, Levin E. Membrane and nuclear estrogen receptor α collaborate to suppress adipogenesis but not triglyceride content. FASEB J. 2016;30:230-40 pubmed publisher
  22. Manna S, Kim J, Baugé C, Cam M, Zhao Y, Shetty J, et al. Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation. Nat Commun. 2015;6:8152 pubmed publisher
  23. Shanle E, Onitilo A, Huang W, Kim K, Zang C, Engel J, et al. Prognostic significance of full-length estrogen receptor beta expression in stage I-III triple negative breast cancer. Am J Transl Res. 2015;7:1246-59 pubmed
  24. Montt Guevara M, Giretti M, Russo E, Giannini A, Mannella P, Genazzani A, et al. Estetrol Modulates Endothelial Nitric Oxide Synthesis in Human Endothelial Cells. Front Endocrinol (Lausanne). 2015;6:111 pubmed publisher
  25. Cookman C, Belcher S. Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma. Endocrinology. 2015;156:2395-408 pubmed publisher
  26. Maliqueo M, Sundström Poromaa I, Vanky E, Fornes R, Benrick A, Åkerud H, et al. Placental STAT3 signaling is activated in women with polycystic ovary syndrome. Hum Reprod. 2015;30:692-700 pubmed publisher
  27. Harvey C, Chen J, Bagnell C, Uzumcu M. Methoxychlor and its metabolite HPTE inhibit cAMP production and expression of estrogen receptors α and β in the rat granulosa cell in vitro. Reprod Toxicol. 2015;51:72-8 pubmed publisher
  28. Wimberly H, Han G, Pinnaduwage D, Murphy L, Yang X, Andrulis I, et al. ER? splice variant expression in four large cohorts of human breast cancer patient tumors. Breast Cancer Res Treat. 2014;146:657-67 pubmed publisher
  29. von Roemeling C, Radisky D, Marlow L, Cooper S, Grebe S, ANASTASIADIS P, et al. Neuronal pentraxin 2 supports clear cell renal cell carcinoma by activating the AMPA-selective glutamate receptor-4. Cancer Res. 2014;74:4796-810 pubmed publisher
  30. Welsh A, Harigopal M, Wimberly H, Prasad M, Rimm D. Quantitative analysis of estrogen receptor expression shows SP1 antibody is more sensitive than 1D5. Appl Immunohistochem Mol Morphol. 2013;21:139-47 pubmed publisher
  31. Vivar O, Saunier E, Leitman D, Firestone G, Bjeldanes L. Selective activation of estrogen receptor-beta target genes by 3,3'-diindolylmethane. Endocrinology. 2010;151:1662-7 pubmed publisher
  32. Charn T, Liu E, Chang E, Lee Y, Katzenellenbogen J, Katzenellenbogen B. Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selection. Mol Endocrinol. 2010;24:47-59 pubmed publisher