This is a Validated Antibody Database (VAD) review about human EME1, based on 4 published articles (read how Labome selects the articles), using EME1 antibody in all methods. It is aimed to help Labome visitors find the most suited EME1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
EME1 synonym: MMS4L; SLX2A; crossover junction endonuclease EME1; MMS4 homolog; SLX2 structure-specific endonuclease subunit homolog A; essential meiotic endonuclease 1 homolog 1; essential meiotic endonuclease 1 homolog 2; hMMS4; homolog of yeast EME1 endonuclease

Santa Cruz Biotechnology
mouse monoclonal (MTA31 7h2/1)
  • western blot; human; fig 1B
Santa Cruz Biotechnology EME1 antibody (Santa Cruz, MTA31 7h2/1) was used in western blot on human samples (fig 1B). Mol Cell (2017) ncbi
mouse monoclonal (MTA31 7h2/1)
  • western blot; human; fig 1
Santa Cruz Biotechnology EME1 antibody (Santa Cruz, sc-53275) was used in western blot on human samples (fig 1). Cell (2014) ncbi
ImmuQuest
mouse monoclonal ('7h2/1)
  • western blot; human; fig 8
ImmuQuest EME1 antibody (ImmuQuest, IQ284) was used in western blot on human samples (fig 8). Mol Cell Proteomics (2015) ncbi
mouse monoclonal ('7h2/1)
  • western blot; human
In order to study a novel Fanconi anemia subtype in which SLX4 is mutated, ImmuQuest EME1 antibody (ImmuQuest, IQ284) was used in western blot on human samples . Nat Genet (2011) ncbi
Abcam
mouse polyclonal
  • western blot; human; fig 1
Abcam EME1 antibody (Abcam, ab88878) was used in western blot on human samples (fig 1). Cell (2014) ncbi
Articles Reviewed
  1. Wyatt H, Laister R, Martin S, Arrowsmith C, West S. The SMX DNA Repair Tri-nuclease. Mol Cell. 2017;65:848-860.e11 pubmed publisher
  2. Xiao Z, Chang J, Hendriks I, Sigurðsson J, Olsen J, Vertegaal A. System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability. Mol Cell Proteomics. 2015;14:1419-34 pubmed publisher
  3. Laguette N, Brégnard C, Hue P, Basbous J, Yatim A, Larroque M, et al. Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing. Cell. 2014;156:134-45 pubmed publisher
  4. Stoepker C, Hain K, Schuster B, Hilhorst Hofstee Y, Rooimans M, Steltenpool J, et al. SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet. 2011;43:138-41 pubmed publisher