This is a Validated Antibody Database (VAD) review about human EMC2, based on 5 published articles (read how Labome selects the articles), using EMC2 antibody in all methods. It is aimed to help Labome visitors find the most suited EMC2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
EMC2 synonym: KIAA0103; TTC35; ER membrane protein complex subunit 2; TPR repeat protein 35; tetratricopeptide repeat domain 35; tetratricopeptide repeat protein 35

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (D-7)
  • western blot knockout validation; human; 1:200; fig 2
In order to suggest a role for ER-associated protein degradation in West Nile virus-induced cell death, Santa Cruz Biotechnology EMC2 antibody (santa Cruz, Sc166011) was used in western blot knockout validation on human samples at 1:200 (fig 2). Cell Rep (2015) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 1b
Proteintech Group EMC2 antibody (Proteintech, 25443-1-AP) was used in western blot on human samples at 1:2000 (fig 1b). J Cell Sci (2019) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4d
Proteintech Group EMC2 antibody (Proteintech, 25443-1-AP) was used in western blot on human samples (fig 4d). Science (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4e
Proteintech Group EMC2 antibody (Proteintech, 25443-1-AP) was used in western blot on human samples (fig 4e). EMBO Mol Med (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-7)
  • western blot knockout validation; human; 1:200; fig 2
In order to suggest a role for ER-associated protein degradation in West Nile virus-induced cell death, Santa Cruz Biotechnology EMC2 antibody (santa Cruz, Sc166011) was used in western blot knockout validation on human samples at 1:200 (fig 2). Cell Rep (2015) ncbi
mouse monoclonal (D-7)
  • western blot; human; fig 7
Santa Cruz Biotechnology EMC2 antibody (Santa Cruz Biotechnology, sc-166011) was used in western blot on human samples (fig 7). Genome Med (2012) ncbi
Articles Reviewed
  1. Volkmar N, Thezenas M, Louie S, Juszkiewicz S, Nomura D, Hegde R, et al. The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis. J Cell Sci. 2019;132: pubmed publisher
  2. Guna A, Volkmar N, Christianson J, Hegde R. The ER membrane protein complex is a transmembrane domain insertase. Science. 2018;359:470-473 pubmed publisher
  3. Janer A, Prudent J, Paupe V, Fahiminiya S, Majewski J, Sgarioto N, et al. SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome. EMBO Mol Med. 2016;8:1019-38 pubmed publisher
  4. Ma H, Dang Y, Wu Y, Jia G, Anaya E, Zhang J, et al. A CRISPR-Based Screen Identifies Genes Essential for West-Nile-Virus-Induced Cell Death. Cell Rep. 2015;12:673-83 pubmed publisher
  5. Louie R, Guo J, Rodgers J, White R, Shah N, Pagant S, et al. A yeast phenomic model for the gene interaction network modulating CFTR-?F508 protein biogenesis. Genome Med. 2012;4:103 pubmed publisher